etanercept 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
Tumour Necrosis Factor (TNF) receptors 4978 185243-69-0

Description:

MoleculeDescription

Synonyms:

  • etanercept-szzs
  • erelzi
  • etanercept
  • enbrel
  • TNR 001
  • TNR-001
  • etanercept (genetical recombination)
A recombinant version of soluble human TNF receptor fused to an IgG FC fragment that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS.
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
7 mg P

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Jan. 19, 2005 PMDA WYETH LEDERLE JAPAN, WYETH
Nov. 2, 1998 FDA IMMUNEX
Feb. 3, 2000 EMA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Injection site erythema 39616.98 13.85 21455 951472 55993 55263147
Injection site pain 39290.26 13.85 24664 948263 92454 55226686
Injection site pruritus 22177.45 13.85 11895 961032 30036 55289104
Injection site swelling 21285.73 13.85 11728 961199 31850 55287290
Injection site reaction 16569.28 13.85 10720 962207 42527 55276613
Injection site bruising 13087.20 13.85 8201 964726 30320 55288820
Injection site warmth 11665.86 13.85 5442 967485 8801 55310339
Rheumatoid arthritis 9862.55 13.85 20894 952033 361710 54957430
Drug ineffective 8628.75 13.85 34877 938050 884112 54435028
Injection site rash 6678.59 13.85 3971 968956 12987 55306153
Psoriasis 5971.96 13.85 7676 965251 85016 55234124
Arthralgia 5797.24 13.85 20401 952526 481268 54837872
Injection site urticaria 5525.75 13.85 3180 969747 9603 55309537
Wrong technique in product usage process 5353.73 13.85 5784 967143 52384 55266756
Injection site haemorrhage 5332.48 13.85 3813 969114 18388 55300752
Joint swelling 3575.22 13.85 12064 960863 277736 55041404
Therapeutic product effect decreased 3477.94 13.85 8478 964449 160974 55158166
Injection site discolouration 3366.09 13.85 1891 971036 5368 55313772
Therapeutic product effect incomplete 3244.47 13.85 6237 966690 99794 55219346
Injection site induration 3190.88 13.85 1940 970987 6675 55312465
Pain in extremity 2909.64 13.85 11486 961441 285945 55033195
Acute kidney injury 2881.52 13.85 379 972548 240384 55078756
Toxicity to various agents 2771.71 13.85 319 972608 224245 55094895
Hypotension 2723.56 13.85 516 972411 249992 55069148
Death 2697.43 13.85 1266 971661 340160 54978980
Drug interaction 2626.35 13.85 283 972644 209472 55109668
Product storage error 2624.32 13.85 2025 970902 11188 55307952
Accidental exposure to product 2477.29 13.85 2570 970357 22077 55297063
Pain 2320.31 13.85 19431 953496 643753 54675387
Anaemia 2261.11 13.85 898 972029 266613 55052527
Nasopharyngitis 2244.06 13.85 8639 964288 212320 55106820
Device issue 2237.57 13.85 2265 970662 18841 55300299
Completed suicide 2235.48 13.85 13 972914 133820 55185320
Sinusitis 2130.09 13.85 7875 965052 189706 55129434
Injection site mass 2021.92 13.85 1932 970995 14861 55304279
Treatment failure 1880.17 13.85 6844 966083 163548 55155592
Dyspnoea 1788.31 13.85 4841 968086 587736 54731404
Musculoskeletal stiffness 1771.76 13.85 6326 966601 149681 55169459
Constipation 1693.95 13.85 685 972242 201258 55117882
Febrile neutropenia 1648.53 13.85 36 972891 105509 55213631
Diarrhoea 1600.68 13.85 5676 967251 632831 54686309
Mobility decreased 1583.16 13.85 4517 968410 94474 55224666
Product dose omission issue 1532.60 13.85 7301 965626 197452 55121688
Hyponatraemia 1507.31 13.85 59 972868 102080 55217060
Neutropenia 1460.12 13.85 458 972469 157709 55161431
Swelling 1400.63 13.85 7980 964947 231791 55087349
Thrombocytopenia 1380.08 13.85 329 972598 135895 55183245
Abdominal pain 1364.09 13.85 1477 971450 257328 55061812
Dehydration 1350.86 13.85 527 972400 158298 55160842
Therapeutic response decreased 1341.45 13.85 2876 970051 49882 55269258
Contraindicated product administered 1298.68 13.85 6510 966417 179776 55139364
Injection site haematoma 1293.66 13.85 982 971945 5270 55313870
Drug intolerance 1278.22 13.85 8389 964538 256429 55062711
Injection site discomfort 1252.97 13.85 822 972105 3338 55315802
Vomiting 1244.43 13.85 4432 968495 493796 54825344
Malignant neoplasm progression 1224.12 13.85 8 972919 73579 55245561
Seizure 1151.57 13.85 364 972563 124755 55194385
Musculoskeletal pain 1146.00 13.85 3544 969383 77608 55241532
Cardiac arrest 1144.51 13.85 92 972835 86222 55232918
Joint stiffness 1140.18 13.85 2131 970796 33294 55285846
Disease progression 1128.18 13.85 223 972704 104950 55214190
Intentional overdose 1076.49 13.85 20 972907 68097 55251043
Tachycardia 1063.83 13.85 260 972667 105616 55213524
Hypokalaemia 1063.08 13.85 177 972750 94260 55224880
Drug abuse 1036.73 13.85 28 972899 67582 55251558
Haemoglobin decreased 1036.29 13.85 511 972416 133626 55185514
Bradycardia 1006.14 13.85 36 972891 67468 55251672
Psoriatic arthropathy 989.74 13.85 3172 969755 70836 55248304
Somnolence 975.08 13.85 834 972093 162579 55156561
Arthropathy 946.27 13.85 6313 966614 193962 55125178
Pancytopenia 941.24 13.85 193 972734 88522 55230618
Underdose 938.94 13.85 1564 971363 22193 55296947
Oxygen saturation decreased 922.16 13.85 134 972793 78933 55240207
Overdose 913.12 13.85 343 972584 105487 55213653
Respiratory failure 904.66 13.85 260 972667 94802 55224338
Nausea 904.06 13.85 8658 964269 755520 54563620
Electrocardiogram QT prolonged 897.76 13.85 8 972919 54580 55264560
Pulmonary embolism 893.29 13.85 366 972561 106758 55212382
Synovitis 863.94 13.85 5250 967677 156055 55163085
Renal failure 860.96 13.85 416 972511 110084 55209056
Arthritis 846.53 13.85 3696 969231 96156 55222984
Peripheral swelling 831.03 13.85 6910 966017 227816 55091324
Gastrointestinal haemorrhage 822.99 13.85 157 972770 75794 55243346
Platelet count decreased 818.98 13.85 407 972520 105976 55213164
Decreased appetite 810.44 13.85 1602 971325 217629 55101511
Suicide attempt 803.32 13.85 49 972878 57787 55261353
Depressed level of consciousness 795.47 13.85 44 972883 56389 55262751
Hyperkalaemia 791.52 13.85 18 972909 50847 55268293
Injection site recall reaction 780.37 13.85 287 972640 126 55319014
Syncope 780.09 13.85 450 972477 107749 55211391
Injection site macule 774.23 13.85 303 972624 213 55318927
Respiratory tract congestion 761.17 13.85 1131 971796 14460 55304680
Cardio-respiratory arrest 759.02 13.85 50 972877 55271 55263869
Injection site extravasation 750.45 13.85 813 972114 7371 55311769
Musculoskeletal disorder 741.28 13.85 1249 971678 17898 55301242
Atrial fibrillation 740.47 13.85 485 972442 108412 55210728
Asthenia 730.07 13.85 3247 969680 339726 54979414
Multiple sclerosis relapse 727.27 13.85 9 972918 44894 55274246
Deep vein thrombosis 726.04 13.85 214 972713 76763 55242377
Hypoxia 724.14 13.85 54 972873 53843 55265297
Hypoglycaemia 722.08 13.85 66 972861 55749 55263391
Coma 702.87 13.85 98 972829 59557 55259583
Agitation 696.95 13.85 77 972850 55959 55263181
Sepsis 695.76 13.85 835 972092 139005 55180135
Product use in unapproved indication 695.21 13.85 846 972081 139976 55179164
Weight decreased 671.75 13.85 2036 970891 238678 55080462
Cardiac failure 665.90 13.85 292 972635 81801 55237339
Exposure during pregnancy 659.49 13.85 832 972095 135510 55183630
Finger deformity 653.78 13.85 682 972245 5895 55313245
International normalised ratio increased 651.06 13.85 25 972902 44016 55275124
Knee arthroplasty 650.77 13.85 1961 970966 42298 55276842
Tremor 639.36 13.85 689 972238 120400 55198740
Infection 636.71 13.85 5757 967170 194449 55124691
Injection site irritation 619.55 13.85 560 972367 3976 55315164
Neutrophil count decreased 615.74 13.85 70 972857 49752 55269388
Rhabdomyolysis 608.24 13.85 21 972906 40637 55278503
Dizziness 607.08 13.85 3909 969018 372231 54946909
Surgery 605.35 13.85 1569 971358 30917 55288223
Pleural effusion 604.11 13.85 364 972563 85116 55234024
Blood pressure increased 601.51 13.85 988 971939 144188 55174952
Confusional state 598.42 13.85 1736 971191 206419 55112721
Blood pressure decreased 594.99 13.85 144 972783 58906 55260234
Cardiac failure congestive 585.11 13.85 399 972528 87321 55231819
Lactic acidosis 582.07 13.85 5 972922 35341 55283799
Fear of injection 574.41 13.85 634 972293 5881 55313259
Condition aggravated 573.00 13.85 8749 964178 336149 54982991
Therapy non-responder 572.53 13.85 2339 970588 59016 55260124
Injury associated with device 572.17 13.85 469 972458 2864 55316276
Fall 571.95 13.85 3725 969202 353785 54965355
Metabolic acidosis 571.83 13.85 31 972896 40423 55278717
Plasma cell myeloma 570.34 13.85 68 972859 46578 55272562
Anxiety 567.77 13.85 1594 971333 191578 55127562
Nodule 563.12 13.85 1091 971836 17528 55301612
White blood cell count decreased 556.67 13.85 821 972106 125169 55193971
Hallucination 555.49 13.85 91 972836 49058 55270082
Pulmonary oedema 553.42 13.85 106 972821 51037 55268103
Sedation 539.71 13.85 13 972914 34841 55284299
Skin plaque 539.45 13.85 637 972290 6401 55312739
Injection site vesicles 521.65 13.85 408 972519 2305 55316835
Heart rate increased 521.27 13.85 405 972522 82868 55236272
Drug hypersensitivity 519.70 13.85 7140 965787 268065 55051075
Incorrect dose administered by device 518.74 13.85 469 972458 3331 55315809
Multiple organ dysfunction syndrome 517.55 13.85 136 972791 52634 55266506
Device expulsion 507.91 13.85 3 972924 30446 55288694
Neoplasm progression 503.37 13.85 10 972917 32006 55287134
Neuropathy peripheral 496.31 13.85 629 972298 102264 55216876
Chest pain 495.83 13.85 1653 971274 188144 55130996
Blood creatinine increased 495.66 13.85 395 972532 79796 55239344
Mental status changes 491.41 13.85 42 972885 37459 55281681
Suicidal ideation 488.21 13.85 193 972734 57549 55261591
Foetal exposure during pregnancy 487.33 13.85 23 972904 33800 55285340
C-reactive protein abnormal 482.16 13.85 1567 971360 35242 55283898
Oropharyngeal pain 473.61 13.85 2767 970160 81021 55238119
Red blood cell sedimentation rate abnormal 467.54 13.85 1012 971915 17661 55301479
Injection site inflammation 467.09 13.85 422 972505 2994 55316146
Ascites 465.83 13.85 52 972875 37492 55281648
Hyperglycaemia 462.63 13.85 58 972869 38223 55280917
Therapy interrupted 460.42 13.85 1221 971706 24404 55294736
Orthostatic hypotension 458.39 13.85 29 972898 33170 55285970
Mucosal inflammation 452.18 13.85 94 972833 42716 55276424
Dyspnoea exertional 449.08 13.85 191 972736 54498 55264642
Flushing 443.75 13.85 337 972590 69763 55249377
Encephalopathy 443.19 13.85 47 972880 35278 55283862
Drug dose omission by device 441.35 13.85 400 972527 2851 55316289
Blood bilirubin increased 440.78 13.85 36 972891 33318 55285822
Unresponsive to stimuli 440.16 13.85 27 972900 31698 55287442
Respiratory arrest 437.47 13.85 22 972905 30603 55288537
Cerebrovascular accident 436.39 13.85 649 972278 98621 55220519
Dysarthria 425.75 13.85 83 972844 39467 55279673
Blood alkaline phosphatase increased 425.04 13.85 79 972848 38866 55280274
Alanine aminotransferase increased 419.87 13.85 604 972323 93058 55226082
Drug reaction with eosinophilia and systemic symptoms 416.83 13.85 27 972900 30277 55288863
Influenza 416.55 13.85 2948 969979 92313 55226827
Bronchitis 416.39 13.85 3343 969584 108968 55210172
Serotonin syndrome 413.58 13.85 9 972918 26481 55292659
Hypertension 410.33 13.85 2506 970421 241772 55077368
Pneumonia aspiration 401.84 13.85 45 972882 32366 55286774
Paranasal sinus hypersecretion 401.63 13.85 381 972546 2899 55316241
Hypersensitivity 393.99 13.85 6422 966505 249986 55069154
Pulmonary arterial hypertension 391.88 13.85 15 972912 26488 55292652
Cognitive disorder 390.18 13.85 180 972747 48953 55270187
Alopecia 389.11 13.85 7178 965749 286280 55032860
Inflammation 385.77 13.85 2274 970653 66797 55252343
Osteonecrosis of jaw 383.19 13.85 59 972868 33299 55285841
Transplant dysfunction 377.81 13.85 438 972489 4308 55314832
Dysphagia 377.72 13.85 518 972409 81429 55237711
Hepatic function abnormal 375.22 13.85 71 972856 34487 55284653
Blood pressure systolic increased 375.13 13.85 119 972808 40717 55278423
Foot deformity 374.34 13.85 1081 971846 22744 55296396
Hypomagnesaemia 373.88 13.85 13 972914 25002 55294138
Intentional self-injury 373.50 13.85 13 972914 24979 55294161
Respiratory distress 373.05 13.85 52 972875 31615 55287525
Renal impairment 372.23 13.85 510 972417 80203 55238937
Melaena 367.10 13.85 33 972894 28257 55290883
Drug withdrawal syndrome 364.86 13.85 20 972907 25837 55293303
Aspartate aminotransferase increased 364.04 13.85 539 972388 82063 55237077
Disorientation 361.62 13.85 93 972834 36520 55282620
Acute respiratory failure 360.20 13.85 53 972874 30941 55288199
Adverse reaction 359.63 13.85 611 972316 8816 55310324
Hypervolaemia 356.84 13.85 26 972901 26432 55292708
Chronic kidney disease 356.46 13.85 140 972787 41916 55277224
Palpitations 356.20 13.85 742 972185 98930 55220210
Pulmonary hypertension 355.59 13.85 91 972836 35853 55283287
Blood glucose increased 354.53 13.85 467 972460 74684 55244456
Gamma-glutamyltransferase increased 351.27 13.85 57 972870 30948 55288192
Lymphocyte count decreased 350.94 13.85 37 972890 27902 55291238
Gastrooesophageal reflux disease 350.87 13.85 560 972367 82697 55236443
Loss of consciousness 349.42 13.85 865 972062 108484 55210656
Heart rate decreased 346.92 13.85 132 972795 40295 55278845
Haematochezia 345.86 13.85 161 972766 43557 55275583
Grip strength decreased 345.85 13.85 826 972101 15430 55303710
Pharyngitis streptococcal 345.81 13.85 603 972324 8895 55310245
Oedema 345.24 13.85 551 972376 81369 55237771
Ear infection 344.99 13.85 1258 971669 30037 55289103
Hand deformity 343.48 13.85 3696 969231 130796 55188344
Coronary artery disease 339.24 13.85 61 972866 30735 55288405
Ankylosing spondylitis 337.83 13.85 612 972315 9318 55309822
Acute myocardial infarction 337.41 13.85 59 972868 30334 55288806
Asthma 336.69 13.85 923 972004 111847 55207293
Hepatic failure 336.64 13.85 82 972845 33404 55285736
Blood creatine phosphokinase increased 333.78 13.85 44 972883 27908 55291232
Pneumonia 330.16 13.85 5000 967927 402098 54917042
Fluid retention 328.37 13.85 271 972656 53807 55265333
Bone marrow failure 327.27 13.85 49 972878 28237 55290903
Unevaluable event 324.02 13.85 1656 971271 46031 55273109
Haematemesis 323.28 13.85 54 972873 28704 55290436
Hepatocellular injury 323.26 13.85 39 972888 26475 55292665
Depression 322.41 13.85 1810 971117 178307 55140833
Cholestasis 322.25 13.85 42 972885 26871 55292269
Drug level increased 319.85 13.85 8 972919 20717 55298423
Loss of personal independence in daily activities 319.67 13.85 2455 970472 78914 55240226
General physical health deterioration 316.62 13.85 1686 971241 168324 55150816
Red blood cell sedimentation rate increased 314.15 13.85 1361 971566 35262 55283878
Chest discomfort 312.73 13.85 786 972141 98071 55221069
Rectal haemorrhage 312.47 13.85 163 972764 41304 55277836
Injection site hypersensitivity 310.23 13.85 260 972667 1645 55317495
Jaundice 309.61 13.85 50 972877 27244 55291896
Balance disorder 306.39 13.85 532 972395 75988 55243152
Generalised tonic-clonic seizure 304.95 13.85 54 972873 27512 55291628
Herpes zoster 304.46 13.85 2301 970626 73588 55245552
Blood pressure fluctuation 302.13 13.85 160 972767 40200 55278940
Pyrexia 301.89 13.85 5257 967670 413516 54905624
Delirium 301.80 13.85 180 972747 42337 55276803
Juvenile idiopathic arthritis 301.49 13.85 392 972535 4381 55314759
Myalgia 301.07 13.85 1216 971711 130809 55188331
Psychotic disorder 299.00 13.85 30 972897 23528 55295612
Urinary retention 297.81 13.85 61 972866 28013 55291127
Product quality issue 295.95 13.85 90 972837 31646 55287494
Angioedema 292.13 13.85 177 972750 41276 55277864
Blood urea increased 291.09 13.85 39 972888 24434 55294706
Toxic epidermal necrolysis 290.68 13.85 24 972903 22018 55297122
Haemorrhage 287.54 13.85 330 972597 56067 55263073
Blood calcium decreased 287.24 13.85 36 972891 23733 55295407
Septic shock 283.92 13.85 381 972546 60454 55258686
Systemic lupus erythematosus 283.68 13.85 4530 968397 175548 55143592
Altered state of consciousness 282.80 13.85 33 972894 22988 55296152
Arrhythmia 280.94 13.85 127 972800 34956 55284184
Lethargy 275.50 13.85 289 972638 51152 55267988
Aggression 271.69 13.85 31 972896 21975 55297165
Oedema peripheral 270.33 13.85 1790 971137 169464 55149676
Aphasia 269.96 13.85 94 972833 30321 55288819
Myocardial infarction 269.87 13.85 770 972157 92100 55227040
Ejection fraction decreased 269.01 13.85 19 972908 19822 55299318
Device dislocation 268.94 13.85 36 972891 22570 55296570
Upper respiratory tract infection 267.93 13.85 2129 970798 69159 55249981
Sinus tachycardia 266.39 13.85 36 972891 22408 55296732
Hypocalcaemia 265.60 13.85 83 972844 28677 55290463
Agranulocytosis 265.05 13.85 38 972889 22621 55296519
Circulatory collapse 262.70 13.85 27 972900 20776 55298364
Shock 262.35 13.85 33 972894 21695 55297445
Pancreatitis acute 261.57 13.85 57 972870 25067 55294073
Withdrawal syndrome 261.37 13.85 14 972913 18448 55300692
Impaired healing 260.31 13.85 2467 970460 84374 55234766
Blood potassium decreased 259 13.85 175 972752 38497 55280643
Epilepsy 257.15 13.85 60 972867 25171 55293969
Haematoma 256.25 13.85 116 972811 31903 55287237
Leukopenia 254.35 13.85 527 972400 70413 55248727
Full blood count decreased 253.42 13.85 48 972879 23301 55295839
Cerebral haemorrhage 252.89 13.85 89 972838 28517 55290623
Leukocytosis 251.73 13.85 52 972875 23739 55295401
Diabetic ketoacidosis 250.37 13.85 20 972907 18851 55300289
Stevens-Johnson syndrome 249.39 13.85 45 972882 22618 55296522
Ventricular tachycardia 248.41 13.85 10 972917 16891 55302249
Neurotoxicity 248.03 13.85 5 972922 15790 55303350
Joint destruction 247.14 13.85 367 972560 4688 55314452
Blood pressure diastolic decreased 246.83 13.85 24 972903 19299 55299841
Foot operation 246.78 13.85 412 972515 5855 55313285
Accidental overdose 244.81 13.85 32 972895 20429 55298711
Epistaxis 242.76 13.85 495 972432 66528 55252612
Acute hepatic failure 239.71 13.85 11 972916 16567 55302573
Sinus headache 239.59 13.85 358 972569 4600 55314540
Thrombosis 238.95 13.85 412 972515 59015 55260125
Therapeutic product effect delayed 238.19 13.85 238 972689 1944 55317196
Upper gastrointestinal haemorrhage 238.14 13.85 14 972913 17040 55302100
Myoclonus 237.99 13.85 5 972922 15198 55303942
No adverse event 237.76 13.85 169 972758 36205 55282935
Small intestinal obstruction 237.44 13.85 13 972914 16812 55302328
Contusion 237.32 13.85 3321 969606 125109 55194031
Status epilepticus 236.94 13.85 5 972922 15136 55304004
Electrolyte imbalance 236.79 13.85 20 972907 18013 55301127
Blood lactate dehydrogenase increased 234.23 13.85 38 972889 20637 55298503
Abdominal distension 234.16 13.85 632 972295 76994 55242146
Adverse drug reaction 233.29 13.85 1924 971003 63208 55255932
Posterior reversible encephalopathy syndrome 232.71 13.85 10 972917 15950 55303190
Haematocrit decreased 230.55 13.85 179 972748 36650 55282490
Injection site nodule 230.09 13.85 294 972633 3225 55315915
Rhinorrhoea 227.39 13.85 1727 971200 55310 55263830
Eosinophilia 227.23 13.85 37 972890 20040 55299100
Right ventricular failure 224.06 13.85 15 972912 16364 55302776
Neutropenic sepsis 223.13 13.85 9 972918 15176 55303964
Emotional distress 222.76 13.85 118 972809 29645 55289495
Abnormal behaviour 221.46 13.85 41 972886 20231 55298909
Cerebral infarction 220.65 13.85 58 972869 22447 55296693
Rubber sensitivity 219.90 13.85 218 972709 1762 55317378
Colitis 219.32 13.85 239 972688 41572 55277568
Dyskinesia 218.45 13.85 115 972812 28993 55290147
Increased tendency to bruise 217.96 13.85 506 972421 9272 55309868
Pemphigus 217.24 13.85 3872 969055 153340 55165800
Hallucination, visual 217.18 13.85 24 972903 17444 55301696
Urinary incontinence 216.02 13.85 121 972806 29464 55289676
Neck pain 215.47 13.85 1809 971118 59746 55259394
Gait disturbance 215.00 13.85 3992 968935 159329 55159811
Cardiogenic shock 214.65 13.85 18 972909 16307 55302833
Inappropriate antidiuretic hormone secretion 213.47 13.85 5 972922 13751 55305389
Hemiparesis 213.34 13.85 54 972873 21436 55297704
Hip arthroplasty 211.99 13.85 1266 971661 37357 55281783
Gastritis 211.78 13.85 173 972754 34529 55284611
Joint range of motion decreased 211.71 13.85 935 971992 24430 55294710
Pancreatitis 211.70 13.85 281 972646 44799 55274341
Restlessness 211.69 13.85 97 972830 26489 55292651
Tachypnoea 211.46 13.85 14 972913 15416 55303724
Infusion site pain 209.80 13.85 6 972921 13756 55305384
Rash maculo-papular 208.53 13.85 120 972807 28787 55290353
Myelosuppression 207.16 13.85 28 972899 17427 55301713
Therapy cessation 206.74 13.85 977 971950 26287 55292853
Haematuria 206.42 13.85 104 972823 26883 55292257
COVID-19 205.30 13.85 640 972287 74418 55244722
Sinus congestion 204.61 13.85 668 972259 15056 55304084
Clostridium difficile colitis 204.48 13.85 38 972889 18700 55300440
Pericardial effusion 203.00 13.85 108 972819 27067 55292073
Premature delivery 200.01 13.85 109 972818 26951 55292189
Metastases to bone 199.58 13.85 46 972881 19462 55299678
Respiratory depression 199.13 13.85 3 972924 12432 55306708
Cholelithiasis 198.92 13.85 233 972694 39231 55279909
Coagulopathy 197.83 13.85 41 972886 18675 55300465
Obstructive airways disorder 197.50 13.85 31 972896 17251 55301889
Chondrolysis 197.03 13.85 90 972837 134 55319006
Drug ineffective for unapproved indication 196.54 13.85 99 972828 25594 55293546
Shoulder arthroplasty 195.22 13.85 279 972648 3434 55315706
Knee operation 193.39 13.85 337 972590 4968 55314172
Bone erosion 192.03 13.85 633 972294 14341 55304799
Wheezing 191.87 13.85 659 972268 74367 55244773
Tuberculin test positive 191.63 13.85 262 972665 3085 55316055
Cyanosis 188.50 13.85 25 972902 15785 55303355
Abdominal discomfort 188.00 13.85 6192 966735 271082 55048058
Sinus bradycardia 187.15 13.85 12 972915 13574 55305566
Rheumatoid nodule 186.92 13.85 624 972303 14233 55304907
Poisoning 186.91 13.85 8 972919 12805 55306335
Injection site injury 186.42 13.85 120 972807 468 55318672
Rheumatoid factor positive 185.12 13.85 1917 971010 67143 55251997
Hypothermia 184.56 13.85 7 972920 12463 55306677
Ischaemic stroke 184.12 13.85 34 972893 16808 55302332
Adverse event 183.10 13.85 1607 971320 53769 55265371
Osteonecrosis 182.83 13.85 86 972841 23129 55296011
Neuroleptic malignant syndrome 182.83 13.85 3 972924 11475 55307665
Presyncope 181.98 13.85 108 972819 25474 55293666
Blood sodium decreased 181.73 13.85 79 972848 22255 55296885
Angina pectoris 181.52 13.85 131 972796 27845 55291295
Acute respiratory distress syndrome 180.90 13.85 76 972851 21850 55297290
Face oedema 180.06 13.85 48 972879 18404 55300736
Labelled drug-drug interaction medication error 176.82 13.85 5 972922 11581 55307559
Disturbance in attention 176.28 13.85 181 972746 32359 55286781
Extrapyramidal disorder 176.08 13.85 9 972918 12347 55306793
Intestinal obstruction 173.75 13.85 137 972790 27834 55291306
Gastroenteritis 173.74 13.85 103 972824 24309 55294831
Speech disorder 173.72 13.85 236 972691 37257 55281883
Blood pressure diastolic abnormal 173.42 13.85 6 972921 11592 55307548
Anuria 172.70 13.85 7 972920 11753 55307387
Product prescribing error 171.94 13.85 93 972834 23093 55296047
Subdural haematoma 171.81 13.85 17 972910 13482 55305658
Medication error 170.65 13.85 293 972634 42042 55277098
Transient ischaemic attack 170.57 13.85 197 972730 33380 55285760
Antibiotic therapy 170.29 13.85 141 972786 875 55318265
Premature baby 169.33 13.85 60 972867 19145 55299995
Full blood count abnormal 168.98 13.85 126 972801 26336 55292804
Lymphopenia 168.75 13.85 41 972886 16733 55302407
Chronic obstructive pulmonary disease 168.26 13.85 474 972453 56941 55262199
Dystonia 168.09 13.85 12 972915 12409 55306731
Intentional product misuse 167.37 13.85 1489 971438 50015 55269125
Arthropod bite 167.02 13.85 364 972563 6382 55312758
Brain oedema 165.58 13.85 18 972909 13253 55305887
Cytomegalovirus infection 165.55 13.85 63 972864 19233 55299907
Haemorrhage intracranial 165.16 13.85 15 972912 12740 55306400
Rash 164.19 13.85 10240 962687 482807 54836333
Metastases to liver 163.88 13.85 84 972843 21502 55297638
Bacteraemia 163.66 13.85 35 972892 15596 55303544
Corrective lens user 163.50 13.85 78 972849 136 55319004
Treatment noncompliance 162.93 13.85 194 972733 32429 55286711
Ataxia 161.98 13.85 27 972900 14376 55304764
Hepatic enzyme increased 159.44 13.85 3984 968943 167400 55151740
Complication associated with device 157.43 13.85 36 972891 15314 55303826
Flatulence 157.40 13.85 185 972742 31103 55288037
Transfusion 157.37 13.85 23 972904 13497 55305643
Mycobacterium tuberculosis complex test positive 156.98 13.85 182 972745 1790 55317350
Anhedonia 156.23 13.85 3 972924 9911 55309229
Haemoptysis 155.24 13.85 138 972789 26422 55292718
Acidosis 155.05 13.85 6 972921 10495 55308645
Renal tubular necrosis 153.94 13.85 8 972919 10820 55308320
Mania 153.42 13.85 12 972915 11508 55307632
Cardiomegaly 152.99 13.85 47 972880 16420 55302720
Demyelination 152.90 13.85 336 972591 5926 55313214
Hypothyroidism 152.45 13.85 266 972661 37930 55281210
Tubulointerstitial nephritis 152.27 13.85 49 972878 16616 55302524
Respiratory rate increased 151.66 13.85 17 972910 12220 55306920
Ill-defined disorder 151.54 13.85 1832 971095 66711 55252429
Osteoarthritis 151.34 13.85 2084 970843 78212 55240928
Dyspepsia 151.27 13.85 835 972092 82636 55236504
Vision blurred 151.25 13.85 828 972099 82115 55237025
Infusion site erythema 151.00 13.85 3 972924 9603 55309537
Acne 149.88 13.85 743 972184 20393 55298747
Sleep disorder due to general medical condition, insomnia type 149.72 13.85 1270 971657 42068 55277072
Tricuspid valve incompetence 148.70 13.85 25 972902 13228 55305912
Glossodynia 148.07 13.85 3565 969362 148893 55170247
Left ventricular dysfunction 146.98 13.85 12 972915 11111 55308029
Acute myeloid leukaemia 146.30 13.85 55 972872 16917 55302223
Red blood cell count decreased 146.15 13.85 255 972672 36362 55282778
Decreased immune responsiveness 145.52 13.85 268 972659 4135 55315005
Sleep apnoea syndrome 144.56 13.85 142 972785 25919 55293221
Myelodysplastic syndrome 143.38 13.85 52 972875 16354 55302786
Supraventricular tachycardia 142.81 13.85 28 972899 13263 55305877
Disseminated intravascular coagulation 142.79 13.85 65 972862 17820 55301320
Metastases to central nervous system 142.77 13.85 20 972907 12116 55307024
Parkinsonism 142.52 13.85 5 972922 9541 55309599
Extra dose administered 142.03 13.85 301 972626 5172 55313968
Taste disorder 141.93 13.85 6 972921 9709 55309431
Transaminases increased 141.65 13.85 173 972754 28597 55290543
Dysgeusia 141.59 13.85 310 972617 40605 55278535
Malnutrition 141.39 13.85 34 972893 13974 55305166
Shock haemorrhagic 141.28 13.85 3 972924 9030 55310110
Mitral valve incompetence 140.28 13.85 69 972858 18084 55301056
Ear pain 140.21 13.85 965 971962 29925 55289215
Sneezing 140.18 13.85 587 972340 14973 55304167
Abdominal pain lower 138.59 13.85 117 972810 22975 55296165
Acute generalised exanthematous pustulosis 138.11 13.85 8 972919 9861 55309279
Ileus 137.58 13.85 35 972892 13847 55305293
Joint arthroplasty 137.48 13.85 197 972730 2431 55316709
Urinary tract infection 136.80 13.85 3139 969788 237374 55081766
Hyperhidrosis 135.81 13.85 1009 971918 93079 55226061
Mydriasis 135.66 13.85 16 972911 11055 55308085
Diabetes mellitus inadequate control 135.22 13.85 37 972890 13943 55305197
Injection site papule 134.83 13.85 108 972819 635 55318505
Blood iron abnormal 134.30 13.85 223 972704 3154 55315986
Ventricular fibrillation 133.77 13.85 16 972911 10936 55308204
Cardiac disorder 133.59 13.85 380 972547 45507 55273633
Weight increased 133.44 13.85 2988 969939 226715 55092425
Joint warmth 133.29 13.85 145 972782 1321 55317819
Cholecystitis chronic 133.13 13.85 9 972918 9739 55309401
Blood magnesium decreased 131.90 13.85 23 972904 11851 55307289
Schizophrenia 131.61 13.85 14 972913 10485 55308655
Localised infection 131.39 13.85 868 972059 26544 55292596
Disability 131.17 13.85 581 972346 15199 55303941
Tooth infection 130.20 13.85 579 972348 15173 55303967
Heart rate irregular 130.07 13.85 100 972827 20579 55298561
COVID-19 pneumonia 128.96 13.85 19 972908 11083 55308057
Device related infection 128.70 13.85 113 972814 21767 55297373
Body temperature decreased 128.02 13.85 77 972850 18031 55301109
Oliguria 127.50 13.85 4 972923 8436 55310704
Troponin increased 127.27 13.85 5 972922 8630 55310510
Joint effusion 127.24 13.85 553 972374 14345 55304795
Muscle rigidity 126.92 13.85 17 972910 10654 55308486
Joint injury 126.41 13.85 818 972109 24836 55294304
Frequent bowel movements 126.05 13.85 63 972864 16361 55302779
Spinal operation 125.57 13.85 344 972583 7012 55312128
Myocardial ischaemia 125.09 13.85 28 972899 12088 55307052
Thrombotic microangiopathy 124.78 13.85 10 972917 9401 55309739
Hallucination, auditory 124.40 13.85 24 972903 11500 55307640
Tardive dyskinesia 124.31 13.85 3 972924 8028 55311112
Urine output decreased 123.91 13.85 19 972908 10758 55308382
Anal incontinence 123.83 13.85 30 972897 12268 55306872
Infusion site extravasation 123.63 13.85 4 972923 8206 55310934
Limb operation 123.62 13.85 223 972704 3383 55315757
Vertigo 122.81 13.85 505 972422 54067 55265073
Irritability 122.74 13.85 201 972726 29387 55289753
Intentional product use issue 121.89 13.85 1118 971809 98615 55220525
Hypoalbuminaemia 121.15 13.85 19 972908 10580 55308560
Acute coronary syndrome 119.98 13.85 14 972913 9754 55309386
Nightmare 119.73 13.85 71 972856 16755 55302385
Delusion 119.72 13.85 24 972903 11191 55307949
Clostridium difficile infection 119.26 13.85 178 972749 27020 55292120
Infusion site swelling 118.78 13.85 4 972923 7917 55311223
Muscle spasms 118.68 13.85 1665 971262 135706 55183434
Device failure 118.29 13.85 285 972642 5354 55313786
Joint fluid drainage 117.90 13.85 60 972867 129 55319011
Toxic skin eruption 117.49 13.85 29 972898 11710 55307430
Joint lock 116.84 13.85 165 972762 2007 55317133
Paranoia 116.78 13.85 22 972905 10722 55308418
Prothrombin time prolonged 116.39 13.85 11 972916 9049 55310091
Renal injury 116.29 13.85 10 972917 8877 55310263
Blood albumin decreased 116.07 13.85 45 972882 13583 55305557
Pustular psoriasis 115.89 13.85 246 972681 4232 55314908
Haemodynamic instability 115.80 13.85 7 972920 8322 55310818
Dermatitis atopic 115.31 13.85 7 972920 8292 55310848
Fibromyalgia 115.18 13.85 1554 971373 58049 55261091
Joint noise 115.12 13.85 223 972704 3581 55315559
Malaise 115.09 13.85 7601 965326 360259 54958881
Breast cancer metastatic 114.77 13.85 62 972865 15407 55303733
Drug dependence 114.67 13.85 132 972795 22401 55296739
Atelectasis 114.44 13.85 99 972828 19209 55299931
Device malfunction 114.25 13.85 567 972360 15569 55303571
Myopathy 113.50 13.85 17 972910 9795 55309345
Mental disorder 113.00 13.85 145 972782 23459 55295681
Blood loss anaemia 112.32 13.85 8 972919 8289 55310851
Rash pruritic 111.60 13.85 1395 971532 51199 55267941
Hepatic cytolysis 111.00 13.85 26 972901 10880 55308260
Haematotoxicity 110.89 13.85 9 972918 8374 55310766
Aspiration 110.53 13.85 17 972910 9604 55309536
Lower gastrointestinal haemorrhage 110.05 13.85 3 972924 7184 55311956
Transplant rejection 110.02 13.85 400 972527 9534 55309606
Rales 110.02 13.85 26 972901 10814 55308326
Glomerular filtration rate decreased 109.59 13.85 38 972889 12291 55306849
Walking aid user 109.23 13.85 358 972569 8085 55311055
Drug-induced liver injury 108.92 13.85 274 972653 34188 55284952
Haemodialysis 108.86 13.85 11 972916 8580 55310560
Blood pressure systolic abnormal 108.47 13.85 19 972908 9758 55309382
Cardiac failure acute 108.29 13.85 13 972914 8860 55310280
Cardiomyopathy 108.28 13.85 74 972853 16184 55302956
Cytopenia 108.13 13.85 19 972908 9736 55309404
Cough 108.01 13.85 5511 967416 254450 55064690
Haemorrhoids 107.63 13.85 114 972813 20092 55299048
Lipase increased 107.52 13.85 14 972913 8965 55310175
Headache 107.34 13.85 11130 961797 547914 54771226
Haemolytic anaemia 107.06 13.85 19 972908 9666 55309474
Wrist surgery 107.00 13.85 99 972828 727 55318413
Product complaint 106.70 13.85 35 972892 11725 55307415
White blood cell count increased 106.56 13.85 405 972522 44354 55274786
Insomnia 106.25 13.85 2514 970413 189346 55129794
Nasal congestion 106.18 13.85 1463 971464 54907 55264233
Vaginal haemorrhage 105.94 13.85 175 972752 25498 55293642
Injection site paraesthesia 104.88 13.85 79 972848 418 55318722
Hypophagia 104.76 13.85 213 972714 28663 55290477
Poor venous access 104.21 13.85 41 972886 12265 55306875
Hyperthermia 103.97 13.85 11 972916 8274 55310866
Hospitalisation 103.65 13.85 814 972113 74186 55244954
Hypovolaemia 103.57 13.85 21 972906 9714 55309426
Atrioventricular block first degree 102.94 13.85 3 972924 6762 55312378
Colitis ulcerative 102.76 13.85 164 972763 24227 55294913
Impaired work ability 102.43 13.85 511 972416 14061 55305079
Injury 102.36 13.85 610 972317 59241 55259899
Peritonitis 102.35 13.85 78 972849 16124 55303016
Pneumonitis 102.07 13.85 248 972679 31316 55287824
Oesophagitis 101.89 13.85 58 972869 13999 55305141
Iritis 101.34 13.85 176 972751 2587 55316553
Faecaloma 101.24 13.85 7 972920 7434 55311706
Ventricular extrasystoles 101.03 13.85 31 972896 10839 55308301
Second primary malignancy 100.60 13.85 7 972920 7395 55311745
Hypernatraemia 100.50 13.85 3 972924 6617 55312523
Nephropathy toxic 100.43 13.85 14 972913 8513 55310627
Injection site laceration 100.08 13.85 45 972882 63 55319077
Aplastic anaemia 99.82 13.85 17 972910 8911 55310229
Drug resistance 99.58 13.85 125 972802 20417 55298723
Uterine perforation 98.57 13.85 3 972924 6502 55312638
Pallor 98.36 13.85 166 972761 23983 55295157
Blood potassium increased 98.12 13.85 92 972835 17169 55301971
Klebsiella infection 98.10 13.85 10 972917 7746 55311394
Pharyngitis 96.85 13.85 600 972327 17938 55301202
Sinus disorder 96.63 13.85 652 972275 20082 55299058
Anaphylactic shock 96.57 13.85 141 972786 21599 55297541
Atrioventricular block complete 96.53 13.85 9 972918 7485 55311655
Urosepsis 96.32 13.85 88 972839 16628 55302512
Apathy 96.22 13.85 12 972915 7942 55311198
Hydronephrosis 96.14 13.85 21 972906 9221 55309919
Product substitution issue 95.18 13.85 68 972859 14531 55304609
Myocarditis 94.46 13.85 19 972908 8839 55310301
Enterococcal infection 94.24 13.85 8 972919 7176 55311964
Therapeutic response delayed 94.12 13.85 79 972848 501 55318639
Chromaturia 94.00 13.85 76 972851 15249 55303891
Breast cancer 93.86 13.85 1272 971655 47561 55271579
Normal newborn 93.54 13.85 10 972917 7460 55311680
Skin haemorrhage 93.38 13.85 339 972588 8074 55311066
Tumour lysis syndrome 93.34 13.85 13 972914 7910 55311230
Neutrophil count increased 93.32 13.85 73 972854 14892 55304248
Miosis 93.31 13.85 5 972922 6587 55312553
Bronchospasm 93.28 13.85 80 972847 15589 55303551
Incorrect product administration duration 93.22 13.85 31 972896 10295 55308845
Failure to thrive 92.95 13.85 5 972922 6565 55312575
Ovarian cyst 92.54 13.85 504 972423 14362 55304778
Drug level decreased 92.30 13.85 8 972919 7056 55312084
Eye disorder 92.27 13.85 638 972289 19814 55299326
Secretion discharge 92.01 13.85 394 972533 10152 55308988
Polyneuropathy 91.55 13.85 56 972871 12994 55306146
Proteinuria 91.51 13.85 101 972826 17469 55301671
Muscular weakness 91.26 13.85 1263 971664 103189 55215951
Incorrect disposal of product 91.12 13.85 81 972846 561 55318579
Fine motor skill dysfunction 90.82 13.85 223 972704 4242 55314898
Stress 90.36 13.85 1476 971451 57434 55261706
Chondropathy 90.32 13.85 148 972779 2069 55317071
Hypertensive crisis 89.40 13.85 67 972860 13969 55305171
Respiratory acidosis 89.40 13.85 4 972923 6159 55312981
Viral upper respiratory tract infection 89.18 13.85 302 972625 6940 55312200
Spinal fusion surgery 89.00 13.85 221 972706 4235 55314905
Colitis ischaemic 88.86 13.85 31 972896 9989 55309151
Circumstance or information capable of leading to medication error 88.75 13.85 189 972738 3259 55315881
Hepatomegaly 88.43 13.85 42 972885 11233 55307907
Acute pulmonary oedema 88.25 13.85 13 972914 7584 55311556
Bone pain 88.20 13.85 507 972420 49678 55269462
Faeces discoloured 88.19 13.85 98 972829 16898 55302242
Cholecystitis 88.03 13.85 72 972855 14363 55304777
Lower respiratory tract infection 88.03 13.85 2603 970324 112191 55206949
Psychomotor hyperactivity 87.75 13.85 30 972897 9790 55309350
Tinnitus 87.28 13.85 249 972678 29793 55289347
Swollen tongue 86.88 13.85 253 972674 30071 55289069
Liver function test increased 86.62 13.85 804 972123 27329 55291811
Chills 85.99 13.85 1251 971676 101353 55217787
Hyperlipidaemia 85.91 13.85 112 972815 17997 55301143
Furuncle 85.77 13.85 265 972662 5794 55313346
Anti-cyclic citrullinated peptide antibody positive 85.73 13.85 2272 970655 96328 55222812
Deformity 85.55 13.85 378 972549 9877 55309263
End stage renal disease 85.37 13.85 5 972922 6106 55313034
Abortion induced 85.26 13.85 30 972897 9615 55309525
Bronchitis chronic 85.21 13.85 203 972724 3785 55315355
Limb deformity 85.10 13.85 200 972727 3695 55315445
Sudden death 84.98 13.85 30 972897 9595 55309545
Renal disorder 84.82 13.85 247 972680 29358 55289782
Stress cardiomyopathy 84.59 13.85 20 972907 8316 55310824
Anaphylactic reaction 84.47 13.85 634 972293 58361 55260779
Wound 83.91 13.85 3060 969867 135744 55183396
Deafness transitory 83.69 13.85 133 972794 1809 55317331
Macule 83.45 13.85 122 972805 1535 55317605
Subarachnoid haemorrhage 83.43 13.85 46 972881 11301 55307839
Angina unstable 83.23 13.85 10 972917 6811 55312329
Haemolysis 83.13 13.85 7 972920 6321 55312819
Hepatitis acute 82.95 13.85 21 972906 8336 55310804
Apnoea 82.73 13.85 13 972914 7229 55311911
Dialysis 82.69 13.85 32 972895 9670 55309470
Folliculitis 82.65 13.85 1373 971554 53606 55265534
Metastases to lung 82.60 13.85 50 972877 11668 55307472
Shoulder operation 82.45 13.85 139 972788 1992 55317148
Activated partial thromboplastin time prolonged 82.41 13.85 9 972918 6603 55312537
Lip swelling 82.16 13.85 210 972717 26062 55293078
Hypotonia 82 13.85 24 972903 8653 55310487
Blood lactic acid increased 81.65 13.85 6 972921 6058 55313082
Ageusia 81.17 13.85 58 972869 12393 55306747
Muscle injury 80.74 13.85 1316 971611 51184 55267956
Erythema multiforme 80.63 13.85 32 972895 9522 55309618
Atrial flutter 80.23 13.85 29 972898 9140 55310000
Hemiplegia 79.87 13.85 23 972904 8381 55310759
Incontinence 79.68 13.85 43 972884 10692 55308448
Lung infiltration 79.54 13.85 72 972855 13666 55305474
Device use error 79.45 13.85 241 972686 5215 55313925
Arthrodesis 79.11 13.85 155 972772 2511 55316629
Paraesthesia oral 78.68 13.85 80 972847 14369 55304771
Hepatic necrosis 78.62 13.85 3 972924 5313 55313827
Eosinophil count increased 78.54 13.85 34 972893 9603 55309537
Hiatus hernia 78.29 13.85 137 972790 19515 55299625
Metabolic encephalopathy 78.02 13.85 3 972924 5277 55313863
Limb discomfort 77.58 13.85 752 972175 25870 55293270
Salivary hypersecretion 77.56 13.85 14 972913 7036 55312104
Hyperthyroidism 77.28 13.85 70 972857 13282 55305858
Increased upper airway secretion 76.98 13.85 174 972753 3130 55316010
Polyuria 76.86 13.85 18 972909 7533 55311607
Hip surgery 76.82 13.85 161 972766 2744 55316396
Low birth weight baby 76.79 13.85 9 972918 6249 55312891
Dysuria 76.46 13.85 273 972654 30456 55288684
Macular degeneration 76.06 13.85 131 972796 18777 55300363
Infusion related reaction 76.04 13.85 2897 970030 206034 55113106
Fistula 75.81 13.85 29 972898 8826 55310314
Jaundice cholestatic 75.65 13.85 5 972922 5514 55313626
Scratch 75.58 13.85 241 972686 5362 55313778
Rash papular 74.91 13.85 441 972486 12942 55306198
Head injury 74.86 13.85 205 972722 24861 55294279
Cholecystitis acute 74.85 13.85 18 972909 7398 55311742
Genital haemorrhage 74.69 13.85 14 972913 6848 55312292
Asphyxia 74.44 13.85 7 972920 5782 55313358
Sickle cell anaemia with crisis 73.81 13.85 3 972924 5025 55314115
Uveitis 73.73 13.85 383 972544 10712 55308428
Foetal death 73.72 13.85 28 972899 8559 55310581
Pneumothorax 73.61 13.85 89 972838 14778 55304362
Rash erythematous 73.37 13.85 974 971953 36247 55282893
Enteritis 73.31 13.85 19 972908 7424 55311716
Hospice care 73.13 13.85 10 972917 6170 55312970
Arteriosclerosis 72.94 13.85 36 972891 9417 55309723
Blood triglycerides increased 72.76 13.85 57 972870 11620 55307520
Exostosis 72.72 13.85 475 972452 14468 55304672
Toothache 72.70 13.85 544 972383 17336 55301804
Dementia 72.63 13.85 115 972812 17043 55302097
Depressed mood 71.87 13.85 353 972574 36006 55283134
Aspergillus infection 71.74 13.85 20 972907 7445 55311695
Affect lability 71.65 13.85 43 972884 10082 55309058
Amylase increased 71.56 13.85 8 972919 5763 55313377
Decubitus ulcer 71.33 13.85 40 972887 9735 55309405
Bradyphrenia 71.01 13.85 14 972913 6606 55312534
Bradykinesia 70.91 13.85 3 972924 4851 55314289
Atypical femur fracture 70.91 13.85 4 972923 5043 55314097
Enterocolitis 70.23 13.85 18 972909 7086 55312054
Blood pressure diastolic increased 70.10 13.85 30 972897 8531 55310609
Personality disorder 69.99 13.85 5 972922 5168 55313972
Concomitant disease aggravated 69.84 13.85 29 972898 8397 55310743
Immune system disorder 69.62 13.85 320 972607 8507 55310633
Atrial septal defect 69.28 13.85 14 972913 6492 55312648
Device breakage 69.17 13.85 45 972882 10102 55309038
Blood pressure systolic decreased 68.92 13.85 13 972914 6330 55312810
Vascular device infection 68.69 13.85 8 972919 5582 55313558
Foetal growth restriction 68.26 13.85 19 972908 7080 55312060
Panic attack 68.23 13.85 158 972769 20289 55298851
Hereditary angioedema 68.18 13.85 17 972910 6818 55312322
Onychomycosis 68.08 13.85 259 972668 6313 55312827
Retching 68.05 13.85 80 972847 13450 55305690
Arteriosclerosis coronary artery 67.76 13.85 25 972902 7780 55311360
Forced expiratory volume decreased 67.67 13.85 3 972924 4657 55314483
Bronchopulmonary aspergillosis 67.60 13.85 29 972898 8235 55310905
Granulocytopenia 67.31 13.85 7 972920 5337 55313803
Atrioventricular block 67.04 13.85 18 972909 6869 55312271
Ankle deformity 66.99 13.85 58 972869 386 55318754
Diplopia 66.68 13.85 159 972768 20210 55298930
Cytomegalovirus viraemia 66.35 13.85 6 972921 5114 55314026
Abdominal pain upper 66.30 13.85 2466 970461 175847 55143293
Rheumatoid factor increased 66.16 13.85 103 972824 1375 55317765
Partial seizures 65.52 13.85 8 972919 5382 55313758
Nystagmus 65.33 13.85 11 972916 5814 55313326
Hypertransaminasaemia 65.31 13.85 4 972923 4703 55314437
Hypovolaemic shock 65.26 13.85 8 972919 5365 55313775
Catheter site infection 65.25 13.85 3 972924 4511 55314629
Hypertriglyceridaemia 65.19 13.85 11 972916 5805 55313335
Orthopnoea 65.19 13.85 11 972916 5805 55313335
Ankle operation 65.05 13.85 93 972834 1145 55317995
Diastolic dysfunction 64.79 13.85 10 972917 5635 55313505
Injection site oedema 64.62 13.85 92 972835 1128 55318012
Rib fracture 64.54 13.85 161 972766 20148 55298992
Intestinal ischaemia 64.34 13.85 20 972907 6935 55312205
Product administration error 64.14 13.85 169 972758 20760 55298380
Petechiae 63.56 13.85 79 972848 12960 55306180
Iron deficiency anaemia 63.46 13.85 134 972793 17785 55301355
Premature labour 63.33 13.85 67 972860 11815 55307325
Major depression 63.02 13.85 26 972901 7558 55311582
Irritable bowel syndrome 62.85 13.85 1589 971338 66869 55252271
Skin ulcer 62.84 13.85 977 971950 37631 55281509
Abnormal dreams 62.83 13.85 45 972882 9604 55309536
Abortion spontaneous 62.73 13.85 470 972457 43283 55275857
Off label use 62.70 13.85 8541 964386 547639 54771501
Peripheral sensory neuropathy 62.59 13.85 21 972906 6935 55312205
Device occlusion 62.39 13.85 18 972909 6551 55312589
Gait inability 62.36 13.85 1043 971884 40775 55278365
Duodenal ulcer 61.98 13.85 23 972904 7132 55312008
Cerebral ischaemia 61.93 13.85 15 972912 6135 55313005
Left ventricular hypertrophy 61.57 13.85 7 972920 4977 55314163
Restless legs syndrome 61.48 13.85 125 972802 16822 55302318
Device power source issue 61.20 13.85 59 972868 459 55318681
Mental impairment 61.05 13.85 78 972849 12644 55306496
Somnambulism 60.83 13.85 8 972919 5084 55314056
Discomfort 60.57 13.85 3014 969913 138747 55180393
Elbow deformity 60.25 13.85 98 972829 1361 55317779
Hypoventilation 60.14 13.85 4 972923 4388 55314752
Rhinitis allergic 59.95 13.85 36 972891 8438 55310702
Electrocardiogram abnormal 59.90 13.85 33 972894 8111 55311029
Nephropathy 59.88 13.85 12 972915 5597 55313543
Coma scale abnormal 59.65 13.85 7 972920 4856 55314284
Oligohydramnios 59.62 13.85 15 972912 5979 55313161
Aplasia pure red cell 59.32 13.85 4 972923 4338 55314802
Middle insomnia 59.20 13.85 61 972866 10889 55308251
Ecchymosis 59.10 13.85 55 972872 10301 55308839
Drug level below therapeutic 58.85 13.85 4 972923 4309 55314831
Protein urine present 58.83 13.85 13 972914 5663 55313477
Hyperreflexia 58.69 13.85 10 972917 5240 55313900
Guttate psoriasis 58.05 13.85 51 972876 347 55318793
Application site erythema 58.00 13.85 6 972921 4594 55314546
Amnesia 57.99 13.85 516 972411 45806 55273334
Ketoacidosis 57.97 13.85 3 972924 4072 55315068
Aortic valve incompetence 57.87 13.85 13 972914 5599 55313541
Laryngitis 57.87 13.85 426 972501 13504 55305636
Potentiating drug interaction 57.82 13.85 3 972924 4063 55315077
Skin discolouration 57.68 13.85 874 972053 33482 55285658
Animal bite 57.65 13.85 135 972792 2488 55316652
Peritonitis bacterial 57.60 13.85 7 972920 4726 55314414
Spinal compression fracture 57.54 13.85 86 972841 13048 55306092
Immune thrombocytopenia 57.47 13.85 49 972878 9576 55309564
Spinal pain 57.36 13.85 377 972550 11507 55307633
Ventricular hypokinesia 57.02 13.85 4 972923 4197 55314943
Low turnover osteopathy 56.86 13.85 3 972924 4005 55315135
Pulmonary haemorrhage 56.78 13.85 23 972904 6760 55312380
Dermatitis bullous 56.70 13.85 30 972897 7543 55311597
Pyelonephritis 56.60 13.85 120 972807 15904 55303236
Tuberculosis 56.39 13.85 355 972572 10674 55308466
Proctalgia 56.33 13.85 13 972914 5496 55313644
Pathogen resistance 55.96 13.85 17 972910 5983 55313157
Hypoxic-ischaemic encephalopathy 55.82 13.85 3 972924 3942 55315198
Stillbirth 55.49 13.85 19 972908 6195 55312945
Rhinovirus infection 55.44 13.85 3 972924 3919 55315221
Bundle branch block right 55.43 13.85 8 972919 4739 55314401
Diverticulum intestinal 55.29 13.85 21 972906 6419 55312721
Product physical issue 55.21 13.85 7 972920 4575 55314565
Venous thrombosis 55.18 13.85 7 972920 4573 55314567
C-reactive protein increased 55.18 13.85 1765 971162 76919 55242221
Throat tightness 55.13 13.85 200 972727 22207 55296933
Feeling abnormal 55.12 13.85 2831 970096 130771 55188369
Gallbladder operation 55.08 13.85 116 972811 1984 55317156
Clonus 55.01 13.85 5 972922 4244 55314896
Femoral neck fracture 55.00 13.85 33 972894 7738 55311402
Body height decreased 54.55 13.85 47 972880 9138 55310002
Gastric ulcer 54.46 13.85 203 972724 22360 55296780
Pre-existing condition improved 54.38 13.85 30 972897 7368 55311772
Pulmonary fibrosis 54.28 13.85 768 972159 28990 55290150
Bundle branch block left 54.20 13.85 21 972906 6341 55312799
Maternal drugs affecting foetus 54.15 13.85 11 972916 5082 55314058
Ileus paralytic 54.14 13.85 5 972922 4190 55314950
Rheumatoid factor negative 53.95 13.85 59 972868 541 55318599
Hyperuricaemia 53.85 13.85 11 972916 5062 55314078
Blood phosphorus decreased 53.69 13.85 4 972923 3993 55315147
Pseudomonas infection 53.44 13.85 57 972870 10014 55309126
Nocturia 53.42 13.85 28 972899 7078 55312062
Blood glucose decreased 53.41 13.85 161 972766 18926 55300214
Serum ferritin increased 53.31 13.85 15 972912 5550 55313590
Cardiovascular disorder 53.05 13.85 66 972861 10823 55308317
Diverticulum 52.95 13.85 68 972859 10998 55308142
Systemic inflammatory response syndrome 52.90 13.85 13 972914 5265 55313875
Blood chloride decreased 52.88 13.85 13 972914 5264 55313876
Brain injury 52.47 13.85 22 972905 6333 55312807
Aortic arteriosclerosis 52.43 13.85 16 972911 5614 55313526
Elbow operation 52.30 13.85 42 972885 248 55318892
Wheelchair user 52.23 13.85 210 972717 5256 55313884
Injection site hypoaesthesia 52.03 13.85 49 972878 369 55318771
Escherichia urinary tract infection 51.94 13.85 68 972859 10907 55308233
Central nervous system lesion 51.90 13.85 57 972870 9881 55309259
Obsessive-compulsive disorder 51.87 13.85 3 972924 3703 55315437
Musculoskeletal deformity 51.84 13.85 94 972833 1432 55317708
Blood calcium increased 51.83 13.85 39 972888 8115 55311025
Intestinal perforation 51.76 13.85 68 972859 10891 55308249
Skin mass 51.61 13.85 206 972721 5138 55314002
SLE arthritis 51.59 13.85 59 972868 571 55318569
Upper respiratory tract congestion 51.23 13.85 107 972820 1819 55317321
Iron deficiency 51.10 13.85 22 972905 6234 55312906
Odynophagia 51.06 13.85 27 972900 6791 55312349
Injection site dryness 51.00 13.85 40 972887 227 55318913
Azotaemia 50.97 13.85 6 972921 4152 55314988
Dyslipidaemia 50.85 13.85 23 972904 6330 55312810
Periorbital oedema 50.64 13.85 14 972913 5240 55313900
Blood thyroid stimulating hormone increased 50.63 13.85 25 972902 6538 55312602
Joint surgery 50.47 13.85 45 972882 313 55318827
Supraventricular extrasystoles 50.37 13.85 6 972921 4114 55315026
Surgical failure 50.31 13.85 71 972856 863 55318277
Hot flush 50.29 13.85 540 972387 46186 55272954
Pemphigoid 50.13 13.85 23 972904 6277 55312863
Metabolic disorder 49.99 13.85 16 972911 5445 55313695
Tendon operation 49.61 13.85 42 972885 270 55318870
Eye movement disorder 49.57 13.85 11 972916 4778 55314362
International normalised ratio decreased 49.16 13.85 7 972920 4189 55314951
Cerebral atrophy 49.14 13.85 11 972916 4749 55314391
Pneumonia fungal 49.14 13.85 12 972915 4881 55314259
Meniscus injury 48.98 13.85 234 972693 6324 55312816
Exercise tolerance decreased 48.94 13.85 14 972913 5124 55314016
Culture urine positive 48.94 13.85 3 972924 3525 55315615
Gastrointestinal disorder 48.93 13.85 2400 970527 110302 55208838
Induration 48.93 13.85 79 972848 1090 55318050
Rebound effect 48.92 13.85 5 972922 3865 55315275
Pollakiuria 48.48 13.85 247 972680 24955 55294185
Device dispensing error 48.28 13.85 28 972899 86 55319054
Respiratory syncytial virus infection 48.25 13.85 17 972910 5444 55313696
Post procedural haemorrhage 48.16 13.85 35 972892 7414 55311726
Product dose omission in error 48.06 13.85 9 972918 4405 55314735
Catatonia 47.90 13.85 6 972921 3958 55315182
Unintended pregnancy 47.89 13.85 15 972912 5176 55313964
Haemorrhagic stroke 47.43 13.85 17 972910 5386 55313754
Gastroenteritis viral 47.36 13.85 551 972376 19873 55299267
Tachyarrhythmia 47.27 13.85 8 972919 4213 55314927
Euphoric mood 47.20 13.85 9 972918 4349 55314791
Toe operation 47.06 13.85 59 972868 634 55318506
Blood culture positive 47.02 13.85 9 972918 4337 55314803
Candida infection 46.89 13.85 256 972671 25411 55293729
Thrombocytosis 46.85 13.85 17 972910 5345 55313795
Diarrhoea haemorrhagic 46.75 13.85 42 972885 8001 55311139
Neck surgery 46.75 13.85 97 972830 1641 55317499
Oral mucosal exfoliation 46.69 13.85 92 972835 1497 55317643
Ischaemia 46.41 13.85 10 972917 4433 55314707
Carpal tunnel decompression 46.37 13.85 63 972864 737 55318403
Portal hypertension 46.29 13.85 4 972923 3537 55315603
Blister 46.28 13.85 2314 970613 106573 55212567
Bone lesion 46.13 13.85 18 972909 5412 55313728
Splenomegaly 46.10 13.85 65 972862 10103 55309037
Ventricular septal defect 46.00 13.85 8 972919 4130 55315010
Tongue oedema 45.98 13.85 7 972920 3985 55315155
Electrocardiogram T wave inversion 45.91 13.85 3 972924 3340 55315800
Endodontic procedure 45.90 13.85 133 972794 2803 55316337
Hypogammaglobulinaemia 45.88 13.85 27 972900 6399 55312741
Respiration abnormal 45.82 13.85 20 972907 5621 55313519
Multiple-drug resistance 45.70 13.85 7 972920 3967 55315173
Blood pressure inadequately controlled 45.62 13.85 11 972916 4513 55314627
Haemophagocytic lymphohistiocytosis 45.61 13.85 59 972868 9513 55309627
Dyspnoea at rest 45.53 13.85 6 972921 3807 55315333
Weight fluctuation 45.38 13.85 43 972884 7985 55311155
Blood prolactin increased 45.35 13.85 3 972924 3306 55315834
Patent ductus arteriosus 45.35 13.85 7 972920 3944 55315196
Amenorrhoea 45.33 13.85 53 972874 8933 55310207
Eye operation 45.15 13.85 106 972821 1957 55317183
Cataract operation 45.12 13.85 183 972744 4599 55314541
Pre-eclampsia 45.06 13.85 48 972879 8438 55310702
Brain natriuretic peptide increased 44.79 13.85 13 972914 4713 55314427
Feeling hot 44.79 13.85 991 971936 40796 55278344
Blood thyroid stimulating hormone decreased 44.76 13.85 10 972917 4323 55314817
Ammonia increased 44.70 13.85 10 972917 4319 55314821
Disease recurrence 44.68 13.85 236 972691 23624 55295516
Respiratory rate decreased 44.58 13.85 3 972924 3259 55315881
Bunion operation 44.51 13.85 77 972850 1128 55318012
Acute graft versus host disease 44.43 13.85 9 972918 4166 55314974
Glycosylated haemoglobin increased 44.32 13.85 78 972849 11087 55308053
Dermatitis exfoliative 44.30 13.85 18 972909 5281 55313859
Coordination abnormal 44.18 13.85 95 972832 12526 55306614
Tumour marker increased 44.16 13.85 10 972917 4283 55314857
Cardiac murmur 44.05 13.85 81 972846 11320 55307820
Spinal column injury 43.85 13.85 100 972827 1810 55317330
Depressive symptom 43.68 13.85 5 972922 3536 55315604
Kidney infection 43.65 13.85 549 972378 20176 55298964
Thirst 43.55 13.85 78 972849 11012 55308128
Gastritis erosive 43.39 13.85 21 972906 5556 55313584
Left ventricular failure 43.38 13.85 16 972911 4980 55314160
Hydrocephalus 43.28 13.85 16 972911 4973 55314167
Wrong product administered 43.16 13.85 22 972905 5650 55313490
Flank pain 42.89 13.85 117 972810 14208 55304932
Laryngeal oedema 42.86 13.85 19 972908 5291 55313849
Peripheral ischaemia 42.81 13.85 12 972915 4451 55314689
Embolic stroke 42.70 13.85 6 972921 3627 55315513
Pericarditis 42.68 13.85 2297 970630 106626 55212514
Lip oedema 42.68 13.85 5 972922 3473 55315667
Oxygen consumption increased 42.67 13.85 6 972921 3625 55315515
Muscle twitching 42.64 13.85 141 972786 16101 55303039
Cachexia 42.62 13.85 16 972911 4926 55314214
Sensory disturbance 42.60 13.85 96 972831 12447 55306693
Blood creatine increased 42.56 13.85 18 972909 5155 55313985
Therapy partial responder 42.50 13.85 43 972884 7742 55311398
Bone swelling 42.46 13.85 86 972841 1429 55317711
Staphylococcus test positive 42.39 13.85 6 972921 3607 55315533
Systemic lupus erythematosus rash 42.26 13.85 100 972827 1856 55317284
Personality change 42.16 13.85 24 972903 5793 55313347
Embolism 42.15 13.85 39 972888 7325 55311815
Non-cardiac chest pain 42.04 13.85 25 972902 5891 55313249
Systemic infection 41.91 13.85 4 972923 3265 55315875
Granuloma skin 41.85 13.85 236 972691 6815 55312325
Cyst 41.79 13.85 370 972557 12408 55306732
Pulmonary arterial pressure increased 41.52 13.85 5 972922 3400 55315740
Injection site coldness 41.49 13.85 23 972904 63 55319077
Swelling face 41.43 13.85 700 972227 55369 55263771
Breath sounds abnormal 41.41 13.85 57 972870 8950 55310190
Vulvovaginal mycotic infection 41.37 13.85 182 972745 4746 55314394
Bedridden 41.33 13.85 313 972614 10012 55309128
Back disorder 41.29 13.85 308 972619 9805 55309335
Pelvic pain 40.98 13.85 90 972837 11777 55307363
Musculoskeletal discomfort 40.91 13.85 447 972480 15871 55303269
Lung consolidation 40.80 13.85 9 972918 3925 55315215
Malignant melanoma 40.72 13.85 321 972606 10398 55308742
Vitamin D deficiency 40.64 13.85 94 972833 12076 55307064
Breast cancer stage I 40.64 13.85 29 972898 6201 55312939
Drooling 40.54 13.85 6 972921 3488 55315652
Lymphoedema 40.52 13.85 75 972852 10455 55308685
Pathological fracture 40.50 13.85 48 972879 8041 55311099
Lymphoma 40.00 13.85 313 972614 10115 55309025
Endophthalmitis 39.89 13.85 4 972923 3139 55316001
Pain in jaw 39.81 13.85 471 972456 39565 55279575
Panniculitis 39.76 13.85 299 972628 9543 55309597
Latent tuberculosis 39.75 13.85 114 972813 2388 55316752
Platelet count increased 39.71 13.85 141 972786 15757 55303383
Blood parathyroid hormone decreased 39.56 13.85 264 972663 8100 55311040
Lung transplant 39.44 13.85 3 972924 2944 55316196
Movement disorder 39.33 13.85 184 972743 19014 55300126
Protein total decreased 39.30 13.85 22 972905 5360 55313780
Crohn's disease 39.26 13.85 32 972895 6395 55312745
Anaemia macrocytic 39.25 13.85 4 972923 3099 55316041
Phlebitis 39.17 13.85 30 972897 6186 55312954
Malabsorption 39.11 13.85 9 972918 3812 55315328
White blood cells urine positive 39.04 13.85 17 972910 4785 55314355
Erythema 39.03 13.85 3166 969761 152773 55166367
Sexual dysfunction 38.89 13.85 6 972921 3382 55315758
Contrast media allergy 38.88 13.85 104 972823 2089 55317051
Large intestine perforation 38.87 13.85 47 972880 7804 55311336
Injection site exfoliation 38.85 13.85 34 972893 230 55318910
Polydipsia 38.84 13.85 5 972922 3230 55315910
Sinus node dysfunction 38.84 13.85 14 972913 4420 55314720
Neutrophilia 38.81 13.85 10 972917 3923 55315217
Physical disability 38.73 13.85 109 972818 2258 55316882
Infection susceptibility increased 38.73 13.85 121 972806 2662 55316478
Cardiac tamponade 38.72 13.85 14 972913 4412 55314728
Intracranial pressure increased 38.72 13.85 15 972912 4530 55314610
Graft versus host disease 38.71 13.85 36 972891 6745 55312395
Blindness 38.66 13.85 175 972752 18246 55300894
Application site pain 38.62 13.85 10 972917 3910 55315230
Eczema 38.41 13.85 279 972648 25874 55293266
Progressive multifocal leukoencephalopathy 38.36 13.85 95 972832 11918 55307222
Red cell distribution width increased 38.22 13.85 64 972863 9276 55309864
Tenoplasty 38.13 13.85 17 972910 23 55319117
Neurogenic bladder 38.07 13.85 4 972923 3025 55316115
Device difficult to use 38.03 13.85 317 972610 10444 55308696
Hypokinesia 38.01 13.85 105 972822 12698 55306442
Drug abuser 38.01 13.85 3 972924 2856 55316284
Purpura 37.95 13.85 76 972851 10286 55308854
Lymphocyte percentage decreased 37.93 13.85 3 972924 2851 55316289
Cerebellar syndrome 37.89 13.85 7 972920 3460 55315680
Urine analysis abnormal 37.88 13.85 17 972910 4700 55314440
Escherichia bacteraemia 37.79 13.85 7 972920 3453 55315687
Thrombotic thrombocytopenic purpura 37.56 13.85 9 972918 3708 55315432
Local reaction 37.33 13.85 51 972876 600 55318540
Fluid intake reduced 37.33 13.85 6 972921 3281 55315859
Neutrophil percentage increased 37.31 13.85 3 972924 2813 55316327
Muscle haemorrhage 37.21 13.85 4 972923 2971 55316169
Urine leukocyte esterase positive 37.16 13.85 5 972922 3123 55316017
Cardiac failure chronic 37.08 13.85 12 972915 4055 55315085
Cystitis haemorrhagic 37.00 13.85 11 972916 3926 55315214
Skin hyperpigmentation 36.70 13.85 24 972903 5373 55313767
Skin reaction 36.60 13.85 366 972561 12697 55306443
Abdominal wall haematoma 36.52 13.85 3 972924 2764 55316376
Incoherent 36.52 13.85 14 972913 4255 55314885
Back pain 36.38 13.85 4656 968271 232514 55086626
Injection site pustule 36.27 13.85 20 972907 54 55319086
Injection site anaesthesia 36.22 13.85 17 972910 28 55319112
Disability assessment scale score increased 36.15 13.85 3 972924 2741 55316399
Dental care 36.14 13.85 63 972864 929 55318211
Anger 35.96 13.85 94 972833 11578 55307562
Necrosis 35.92 13.85 21 972906 4995 55314145
Disturbance in social behaviour 35.80 13.85 5 972922 3036 55316104
Drug screen positive 35.77 13.85 8 972919 3456 55315684
Performance status decreased 35.70 13.85 7 972920 3316 55315824
Eating disorder 35.60 13.85 163 972764 16942 55302198
Blood immunoglobulin E increased 35.30 13.85 5 972922 3004 55316136
Stridor 35.28 13.85 7 972920 3288 55315852
Metastases to lymph nodes 35.12 13.85 46 972881 7377 55311763
Multiple sclerosis 35.10 13.85 309 972618 27493 55291647
Initial insomnia 35.06 13.85 27 972900 5552 55313588
Immune reconstitution inflammatory syndrome 34.97 13.85 28 972899 5646 55313494
Pulmonary alveolar haemorrhage 34.82 13.85 15 972912 4249 55314891
Focal dyscognitive seizures 34.82 13.85 4 972923 2821 55316319
Female genital tract fistula 34.82 13.85 17 972910 4475 55314665
Hyperventilation 34.65 13.85 28 972899 5620 55313520
Galactorrhoea 34.63 13.85 12 972915 3883 55315257
Joint dislocation 34.58 13.85 421 972506 15352 55303788
Pruritus allergic 34.55 13.85 72 972855 1222 55317918
Thrombophlebitis 34.54 13.85 14 972913 4113 55315027
Spider vein 34.50 13.85 33 972894 254 55318886
Red blood cells urine positive 34.47 13.85 5 972922 2951 55316189
Tooth abscess 34.46 13.85 375 972552 13300 55305840
Gallbladder disorder 34.42 13.85 168 972759 17166 55301974
Ventricular hypertrophy 34.41 13.85 7 972920 3231 55315909
Congestive cardiomyopathy 34.29 13.85 30 972897 5789 55313351
Streptococcal infection 34.29 13.85 176 972751 4899 55314241
Scar excision 34.28 13.85 19 972908 52 55319088
Pyelonephritis acute 34.14 13.85 16 972911 4313 55314827
Occult blood positive 34.08 13.85 8 972919 3343 55315797
Fibrin D dimer increased 34.06 13.85 18 972909 4529 55314611
Sensitivity to weather change 33.98 13.85 214 972713 6435 55312705
Escherichia infection 33.96 13.85 97 972830 11602 55307538
Papule 33.94 13.85 164 972763 4453 55314687
Mass excision 33.91 13.85 34 972893 279 55318861
Hepatitis fulminant 33.90 13.85 7 972920 3197 55315943
Gastrointestinal perforation 33.83 13.85 7 972920 3192 55315948
Pulmonary function test decreased 33.81 13.85 10 972917 3581 55315559
Pneumonia bacterial 33.80 13.85 54 972873 7974 55311166
Myositis 33.76 13.85 59 972868 8409 55310731
Diverticulitis 33.74 13.85 835 972092 35017 55284123
Neonatal respiratory distress syndrome 33.69 13.85 4 972923 2750 55316390
Eye infection 33.69 13.85 297 972630 9947 55309193
Psychiatric symptom 33.68 13.85 21 972906 4823 55314317
Device defective 33.63 13.85 79 972848 1459 55317681
Petit mal epilepsy 33.62 13.85 10 972917 3568 55315572
Breast cancer stage II 33.55 13.85 30 972897 5728 55313412
Coronary artery occlusion 33.48 13.85 51 972876 7678 55311462
Renal cyst 33.48 13.85 69 972858 9240 55309900
Ocular icterus 33.30 13.85 10 972917 3546 55315594
Abdominal tenderness 33.29 13.85 50 972877 7571 55311569
Biliary dyskinesia 33.22 13.85 3 972924 2560 55316580
Blood chloride increased 33.21 13.85 3 972924 2559 55316581
Pruritus 33.17 13.85 6084 966843 310539 55008601
Extrasystoles 33.10 13.85 21 972906 4778 55314362
Hip fracture 33.09 13.85 302 972625 26671 55292469
Endocarditis 33.04 13.85 27 972900 5389 55313751
Rash morbilliform 33.02 13.85 6 972921 3001 55316139
Dental operation 33.02 13.85 68 972859 1144 55317996
Hypoaesthesia oral 33.01 13.85 95 972832 11336 55307804
Injection site discharge 33.01 13.85 39 972888 392 55318748
Arterial occlusive disease 32.97 13.85 27 972900 5383 55313757
Hepatitis 32.95 13.85 423 972504 35018 55284122
Exposure via skin contact 32.92 13.85 34 972893 290 55318850
Hyperpyrexia 32.85 13.85 8 972919 3260 55315880
Exposed bone in jaw 32.79 13.85 5 972922 2843 55316297
Human antichimeric antibody positive 32.79 13.85 79 972848 1484 55317656
Intermenstrual bleeding 32.78 13.85 44 972883 6983 55312157
International normalised ratio abnormal 32.73 13.85 6 972921 2982 55316158
Chronic graft versus host disease 32.67 13.85 8 972919 3248 55315892
Low density lipoprotein increased 32.58 13.85 32 972895 5842 55313298
Wrist deformity 32.47 13.85 88 972839 1782 55317358
Motor dysfunction 32.43 13.85 72 972855 9385 55309755
Faeces soft 32.30 13.85 22 972905 4820 55314320
Fracture 32.21 13.85 181 972746 17837 55301303
Self-medication 32.00 13.85 3 972924 2484 55316656
Body height below normal 31.97 13.85 92 972835 1931 55317209
Knee deformity 31.89 13.85 63 972864 1027 55318113
Lupus-like syndrome 31.88 13.85 342 972585 12085 55307055
Retinal haemorrhage 31.71 13.85 21 972906 4670 55314470
Pharyngeal swelling 31.69 13.85 27 972900 5279 55313861
Blood phosphorus increased 31.67 13.85 5 972922 2771 55316369
Plasmacytoma 31.66 13.85 3 972924 2463 55316677
Mucormycosis 31.64 13.85 5 972922 2769 55316371
Neoplasm recurrence 31.63 13.85 3 972924 2461 55316679
Mammoplasty 31.62 13.85 42 972885 480 55318660
Scab 31.59 13.85 216 972711 6682 55312458
Blood uric acid increased 31.47 13.85 17 972910 4225 55314915
Colorectal cancer 31.47 13.85 10 972917 3419 55315721
Post transplant lymphoproliferative disorder 31.47 13.85 21 972906 4651 55314489
Pseudomembranous colitis 31.43 13.85 6 972921 2897 55316243
Periodontitis 31.29 13.85 8 972919 3155 55315985
Injection site cellulitis 31.29 13.85 66 972861 1130 55318010
Bacterial test positive 31.27 13.85 24 972903 4944 55314196
Skin laceration 31.26 13.85 506 972421 19650 55299490
Eyelid ptosis 31.25 13.85 40 972887 6479 55312661
Urine abnormality 31.20 13.85 42 972885 6657 55312483
Scleritis 31.12 13.85 137 972790 3574 55315566
Thyroid neoplasm 31.03 13.85 139 972788 3654 55315486
Areflexia 31.01 13.85 6 972921 2869 55316271
Bilirubin conjugated increased 30.84 13.85 4 972923 2569 55316571
Occupational exposure to product 30.82 13.85 91 972836 1939 55317201
Persecutory delusion 30.79 13.85 4 972923 2566 55316574
Epidural injection 30.75 13.85 10 972917 0 55319140
Drug tolerance decreased 30.74 13.85 361 972566 13050 55306090
Obstruction 30.73 13.85 3 972924 2405 55316735
Peripheral coldness 30.72 13.85 93 972834 10918 55308222
Behaviour disorder 30.70 13.85 5 972922 2708 55316432
Stress at work 30.68 13.85 64 972863 1087 55318053
Faecal calprotectin increased 30.31 13.85 5 972922 2683 55316457
Joint laxity 30.29 13.85 102 972825 2337 55316803
Cytomegalovirus test positive 30.26 13.85 6 972921 2820 55316320
Urine ketone body present 30.23 13.85 3 972924 2374 55316766
Gastrointestinal sounds abnormal 30.11 13.85 14 972913 3791 55315349
Sensitisation 30.09 13.85 3 972924 2365 55316775
Hypoglycaemic coma 30.07 13.85 3 972924 2364 55316776
Abnormal faeces 30.06 13.85 23 972904 4745 55314395
Subileus 30.00 13.85 7 972920 2937 55316203
Dry mouth 30.00 13.85 862 972065 63343 55255797
Rotator cuff repair 29.92 13.85 86 972841 1804 55317336
Jugular vein thrombosis 29.92 13.85 6 972921 2797 55316343
Injection site scar 29.89 13.85 55 972872 848 55318292
Duodenitis 29.81 13.85 11 972916 3423 55315717
Clostridium test positive 29.77 13.85 4 972923 2501 55316639
Post procedural infection 29.74 13.85 246 972681 8086 55311054
Visual field defect 29.57 13.85 37 972890 6052 55313088
Colonoscopy 29.44 13.85 72 972855 1366 55317774
Haemoperitoneum 29.42 13.85 5 972922 2625 55316515
Prescribed overdose 29.40 13.85 245 972682 22051 55297089
Staphylococcal bacteraemia 29.33 13.85 28 972899 5181 55313959
Inflammatory marker increased 29.27 13.85 193 972734 5897 55313243
Oesophageal pain 29.27 13.85 10 972917 3265 55315875
Feeling cold 29.23 13.85 230 972697 20957 55298183
Lacunar infarction 29.17 13.85 9 972918 3136 55316004
Orthosis user 29.17 13.85 19 972908 76 55319064
Laryngospasm 29.11 13.85 7 972920 2877 55316263
Carpal tunnel syndrome 29.08 13.85 458 972469 17686 55301454
Sensory loss 29.05 13.85 70 972857 8865 55310275
Injection site plaque 28.98 13.85 19 972908 77 55319063
Coronary artery stenosis 28.88 13.85 21 972906 4447 55314693
Autonomic nervous system imbalance 28.85 13.85 5 972922 2588 55316552
Increased appetite 28.74 13.85 68 972859 8667 55310473
General symptom 28.73 13.85 106 972821 2545 55316595
Cold sweat 28.72 13.85 95 972832 10848 55308292
Conjunctival haemorrhage 28.67 13.85 10 972917 3223 55315917
Periorbital swelling 28.65 13.85 3 972924 2275 55316865
Cholangitis 28.58 13.85 26 972901 4923 55314217
Pulmonary thrombosis 28.54 13.85 60 972867 7977 55311163
Dysphoria 28.48 13.85 25 972902 4817 55314323
Accident 28.45 13.85 177 972750 5299 55313841
Malignant pleural effusion 28.38 13.85 4 972923 2412 55316728
Urticaria 28.37 13.85 2886 970041 141790 55177350
Proctitis 28.35 13.85 5 972922 2555 55316585
Ventricular dysfunction 28.34 13.85 6 972921 2693 55316447
Bipolar disorder 28.28 13.85 55 972872 7525 55311615
Enthesopathy 28.21 13.85 237 972690 7826 55311314
Diabetic retinopathy 28.19 13.85 3 972924 2246 55316894
Wound dehiscence 28.16 13.85 23 972904 4592 55314548
Polycystic ovaries 28.13 13.85 11 972916 3303 55315837
Non-small cell lung cancer 28.12 13.85 14 972913 3644 55315496
Carotid artery stenosis 28.11 13.85 26 972901 4884 55314256
Caesarean section 28.03 13.85 163 972764 15928 55303212
Animal scratch 28.02 13.85 59 972868 1009 55318131
Urinary tract infection bacterial 28.00 13.85 22 972905 4478 55314662
Leukoencephalopathy 27.97 13.85 18 972909 4064 55315076
Oral pain 27.83 13.85 305 972622 25988 55293152
Skin papilloma 27.81 13.85 152 972775 4337 55314803
Aortic stenosis 27.78 13.85 21 972906 4359 55314781
Haemarthrosis 27.72 13.85 9 972918 3035 55316105
Thinking abnormal 27.71 13.85 84 972843 9857 55309283
Ankle arthroplasty 27.68 13.85 71 972856 1389 55317751
Sciatica 27.61 13.85 616 972311 25394 55293746
Temperature regulation disorder 27.60 13.85 22 972905 4446 55314694
Appendicitis 27.53 13.85 53 972874 7279 55311861
Hepatic lesion 27.50 13.85 20 972907 4235 55314905
Mucous stools 27.48 13.85 12 972915 3372 55315768
Immobile 27.45 13.85 176 972751 5326 55313814
Live birth 27.43 13.85 212 972715 19393 55299747
Ischaemic cardiomyopathy 27.41 13.85 4 972923 2350 55316790
Dental implantation 27.36 13.85 44 972883 605 55318535
Self-injurious ideation 27.35 13.85 4 972923 2346 55316794
Clostridial infection 27.30 13.85 19 972908 4116 55315024
Exposure to communicable disease 27.26 13.85 41 972886 530 55318610
Lung opacity 27.21 13.85 4 972923 2337 55316803
Epstein-Barr virus infection 27.11 13.85 55 972872 7408 55311732
Ear congestion 27.04 13.85 91 972836 2084 55317056
Rotator cuff syndrome 27.01 13.85 325 972602 11818 55307322
Macular oedema 27.01 13.85 16 972911 3778 55315362
Adjustment disorder 26.93 13.85 4 972923 2319 55316821
Eyelid oedema 26.90 13.85 83 972844 9685 55309455
Bone graft 26.80 13.85 52 972875 836 55318304
Product administered at inappropriate site 26.66 13.85 104 972823 2566 55316574
Arthropod sting 26.61 13.85 57 972870 987 55318153
Loose body in joint 26.60 13.85 64 972863 1201 55317939
Acute graft versus host disease in skin 26.57 13.85 11 972916 3191 55315949
Microcytic anaemia 26.57 13.85 11 972916 3191 55315949
Cardiopulmonary failure 26.49 13.85 13 972914 3412 55315728
Duodenal ulcer haemorrhage 26.44 13.85 4 972923 2288 55316852
Lack of injection site rotation 26.43 13.85 31 972896 309 55318831
Hepatitis toxic 26.41 13.85 9 972918 2943 55316197
Small for dates baby 26.40 13.85 14 972913 3516 55315624
Rheumatoid lung 26.39 13.85 116 972811 3024 55316116
Product availability issue 26.36 13.85 10 972917 3059 55316081
Nerve injury 26.31 13.85 253 972674 8684 55310456
Heavy menstrual bleeding 26.25 13.85 168 972759 16041 55303099
Nail pitting 26.17 13.85 27 972900 230 55318910
Nail disorder 26.14 13.85 308 972619 11143 55307997
Normochromic normocytic anaemia 26.14 13.85 22 972905 4327 55314813
Tonsillar ulcer 26.03 13.85 29 972898 272 55318868
Anxiety disorder 25.96 13.85 17 972910 3803 55315337
Ovarian neoplasm 25.92 13.85 51 972876 829 55318311
Nasal polyps 25.86 13.85 12 972915 3253 55315887
Burn infection 25.86 13.85 14 972913 36 55319104
Nasal discharge discolouration 25.82 13.85 81 972846 1786 55317354
Blood parathyroid hormone increased 25.74 13.85 9 972918 2896 55316244
Escherichia sepsis 25.67 13.85 24 972903 4485 55314655
Dermatitis allergic 25.59 13.85 361 972566 13617 55305523
Urinary sediment present 25.56 13.85 3 972924 2081 55317059
Gangrene 25.53 13.85 35 972892 5505 55313635
Spinal cord compression 25.50 13.85 17 972910 3767 55315373
Device related sepsis 25.47 13.85 17 972910 3765 55315375
Hangnail 25.47 13.85 11 972916 13 55319127
Hypertensive heart disease 25.34 13.85 5 972922 2358 55316782
Skin swelling 25.28 13.85 99 972828 2447 55316693
Tooth extraction 25.17 13.85 263 972664 9230 55309910
Mesenteritis 25.16 13.85 26 972901 222 55318918
Swelling of eyelid 25.14 13.85 6 972921 2479 55316661
Anal fistula 25.03 13.85 10 972917 2964 55316176
Social avoidant behaviour 24.99 13.85 9 972918 2843 55316297
Dilatation ventricular 24.96 13.85 5 972922 2333 55316807
Intervertebral disc operation 24.92 13.85 47 972880 739 55318401
Intra-abdominal haemorrhage 24.89 13.85 5 972922 2328 55316812
Pseudomonal sepsis 24.80 13.85 4 972923 2182 55316958
Oral surgery 24.74 13.85 57 972870 1039 55318101
Dissociation 24.70 13.85 7 972920 2578 55316562
Neurological decompensation 24.68 13.85 6 972921 2448 55316692
Polyarthritis 24.67 13.85 245 972682 8483 55310657
Communication disorder 24.58 13.85 5 972922 2308 55316832
Gout 24.52 13.85 118 972809 12103 55307037
Tenosynovitis 24.52 13.85 326 972601 12135 55307005
Oral candidiasis 24.37 13.85 207 972720 18556 55300584
Metastasis 24.37 13.85 28 972899 4756 55314384
Paraparesis 24.29 13.85 4 972923 2149 55316991
Affective disorder 24.24 13.85 37 972890 5566 55313574
Extravasation 24.20 13.85 4 972923 2143 55316997
Procedural pain 24.18 13.85 173 972754 16098 55303042
Decreased activity 24.17 13.85 37 972890 5559 55313581
Generalised oedema 24.15 13.85 149 972778 14352 55304788
Refusal of treatment by patient 24.14 13.85 32 972895 5106 55314034
Internal haemorrhage 24.14 13.85 28 972899 4736 55314404
Injection site infection 24.01 13.85 76 972851 1684 55317456
Haemolytic uraemic syndrome 24.00 13.85 6 972921 2402 55316738
Alcohol abuse 23.98 13.85 3 972924 1981 55317159
Menopause 23.98 13.85 95 972832 2361 55316779
Epicondylitis 23.96 13.85 83 972844 1930 55317210
Hypertonic bladder 23.91 13.85 13 972914 3219 55315921
Micturition urgency 23.91 13.85 75 972852 8706 55310434
Cellulitis 23.86 13.85 1055 971872 73894 55245246
Skin injury 23.84 13.85 72 972855 1554 55317586
Hepatotoxicity 23.64 13.85 387 972540 30766 55288374
Reversible cerebral vasoconstriction syndrome 23.54 13.85 6 972921 2371 55316769
Helicobacter infection 23.53 13.85 1518 971409 71750 55247390
Injection site erosion 23.51 13.85 16 972911 70 55319070
Anal fissure 23.49 13.85 19 972908 3812 55315328
Acute lymphocytic leukaemia 23.47 13.85 9 972918 2735 55316405
Intraventricular haemorrhage 23.40 13.85 3 972924 1944 55317196
Synovial cyst 23.37 13.85 253 972674 8961 55310179
Essential hypertension 23.33 13.85 28 972899 4665 55314475
Biliary colic 23.31 13.85 15 972912 3387 55315753
Paralysis 23.30 13.85 79 972848 8953 55310187
Pneumonia klebsiella 23.17 13.85 5 972922 2214 55316926
Hypoproteinaemia 23.10 13.85 3 972924 1925 55317215
Alcoholism 23.02 13.85 5 972922 2204 55316936
Body temperature abnormal 23.01 13.85 70 972857 1517 55317623
Choking 23.00 13.85 79 972848 8918 55310222
Drug effective for unapproved indication 22.93 13.85 8 972919 2578 55316562
Autoimmune haemolytic anaemia 22.91 13.85 24 972903 4252 55314888
Haemorrhoidal haemorrhage 22.83 13.85 21 972906 3955 55315185
Product label confusion 22.80 13.85 53 972874 972 55318168
Intervertebral disc protrusion 22.78 13.85 513 972414 21181 55297959
Intramedullary rod insertion 22.72 13.85 4 972923 2047 55317093
Procedural haemorrhage 22.72 13.85 8 972919 2563 55316577
Cell death 22.69 13.85 6 972921 2313 55316827
Hypopnoea 22.67 13.85 7 972920 2438 55316702
Paranasal sinus discomfort 22.60 13.85 117 972810 3268 55315872
Acute psychosis 22.58 13.85 6 972921 2306 55316834
Intestinal haemorrhage 22.49 13.85 17 972910 3529 55315611
Arteriospasm coronary 22.48 13.85 18 972909 3629 55315511
Cyst removal 22.47 13.85 33 972894 417 55318723
Lactose intolerance 22.46 13.85 9 972918 2663 55316477
Hepatic cyst 22.37 13.85 30 972897 4763 55314377
Iridocyclitis 22.34 13.85 88 972839 2181 55316959
Haemothorax 22.34 13.85 4 972923 2022 55317118
Haemoglobin abnormal 22.33 13.85 28 972899 4576 55314564
Onychomadesis 22.32 13.85 149 972778 4572 55314568
Reaction to preservatives 22.29 13.85 23 972904 196 55318944
Dysaesthesia 22.17 13.85 23 972904 4093 55315047
Large intestinal ulcer 22.15 13.85 14 972913 3192 55315948
Growth failure 22.12 13.85 28 972899 304 55318836
Mass 22.08 13.85 328 972599 12511 55306629
Upper-airway cough syndrome 22.05 13.85 255 972672 9183 55309957
Prosthesis user 21.97 13.85 15 972912 66 55319074
Metastases to meninges 21.97 13.85 6 972921 2264 55316876
Appetite disorder 21.95 13.85 51 972876 6542 55312598
Spinal osteoarthritis 21.92 13.85 158 972769 14678 55304462
Bradyarrhythmia 21.88 13.85 4 972923 1992 55317148
Compression fracture 21.87 13.85 44 972883 5945 55313195
Sarcoidosis 21.86 13.85 166 972761 5314 55313826
Gastric ulcer haemorrhage 21.84 13.85 29 972898 4624 55314516
Gastrointestinal necrosis 21.83 13.85 9 972918 2617 55316523
Central venous catheterisation 21.82 13.85 8 972919 2499 55316641
Maternal exposure before pregnancy 21.75 13.85 54 972873 6769 55312371
Nasal ulcer 21.72 13.85 79 972848 1883 55317257
Hyperaemia 21.71 13.85 5 972922 2117 55317023
Hypochromic anaemia 21.69 13.85 3 972924 1835 55317305
Skin fissures 21.64 13.85 257 972670 9316 55309824
Bruxism 21.64 13.85 14 972913 3152 55315988
Eosinophilic pneumonia 21.59 13.85 4 972923 1973 55317167
Blood sodium increased 21.55 13.85 8 972919 2480 55316660
Cardiac dysfunction 21.48 13.85 4 972923 1966 55317174
Liver transplant 21.47 13.85 6 972921 2230 55316910
Monocyte count decreased 21.33 13.85 4 972923 1956 55317184
Escherichia test positive 21.31 13.85 6 972921 2219 55316921
Ligament rupture 21.26 13.85 106 972821 2916 55316224
Injection related reaction 21.25 13.85 39 972888 600 55318540
Investigation abnormal 21.22 13.85 72 972855 1656 55317484
Nocardiosis 21.22 13.85 3 972924 1805 55317335
Hypercalcaemia 21.21 13.85 310 972617 25101 55294039
Troponin I increased 21.10 13.85 5 972922 2076 55317064
Vaginal discharge 21.07 13.85 47 972880 6116 55313024
Organ failure 21.06 13.85 8 972919 2445 55316695
Osteoporosis 21.04 13.85 1101 971826 50951 55268189
Mean cell haemoglobin concentration decreased 21.03 13.85 15 972912 3208 55315932
Haemoglobin increased 20.95 13.85 16 972911 3304 55315836
Enuresis 20.92 13.85 7 972920 2316 55316824
Metastases to peritoneum 20.92 13.85 13 972914 2991 55316149
Neutrophil count abnormal 20.86 13.85 10 972917 2660 55316480
Dyschezia 20.83 13.85 5 972922 2058 55317082
Mood altered 20.83 13.85 140 972787 13215 55305925
Arthritis infective 20.80 13.85 175 972752 5781 55313359
Humerus fracture 20.77 13.85 71 972856 8026 55311114
Blood immunoglobulin G decreased 20.74 13.85 6 972921 2180 55316960
Basal cell carcinoma 20.72 13.85 577 972350 24644 55294496
Vulvovaginal candidiasis 20.69 13.85 13 972914 2973 55316167
Mean cell volume increased 20.67 13.85 15 972912 3180 55315960
Fibrosis 20.67 13.85 22 972905 3869 55315271
Product preparation error 20.65 13.85 32 972895 4784 55314356
Autoimmune hepatitis 20.63 13.85 69 972858 7852 55311288
Herpes simplex 20.62 13.85 64 972863 7454 55311686
Left atrial dilatation 20.56 13.85 3 972924 1763 55317377
Large intestinal stenosis 20.56 13.85 3 972924 1763 55317377
Oesophageal candidiasis 20.50 13.85 37 972890 5208 55313932
Dactylitis 20.49 13.85 81 972846 2011 55317129
Eye irritation 20.43 13.85 220 972707 18808 55300332
Diffuse large B-cell lymphoma recurrent 20.42 13.85 3 972924 1754 55317386
Anaemia postoperative 20.38 13.85 6 972921 2155 55316985
Megacolon 20.33 13.85 3 972924 1748 55317392
Haematocrit increased 20.28 13.85 6 972921 2148 55316992
Alcohol use 20.27 13.85 5 972922 2020 55317120
Pulmonary infarction 20.25 13.85 9 972918 2503 55316637
Craniocerebral injury 19.97 13.85 10 972917 2594 55316546
Disease susceptibility 19.91 13.85 21 972906 184 55318956
Mood swings 19.90 13.85 189 972738 16558 55302582
Red cell distribution width decreased 19.87 13.85 68 972859 1571 55317569
Carbohydrate antigen 125 increased 19.87 13.85 10 972917 2587 55316553
Gastric haemorrhage 19.83 13.85 46 972881 5904 55313236
Hyperparathyroidism 19.80 13.85 10 972917 2582 55316558
Upper respiratory tract inflammation 19.78 13.85 9 972918 2468 55316672
Atrial tachycardia 19.76 13.85 7 972920 2234 55316906
Polyp 19.76 13.85 46 972881 5896 55313244
Cutaneous vasculitis 19.70 13.85 146 972781 4638 55314502
Synovial disorder 19.65 13.85 53 972874 1070 55318070
Fungal infection 19.58 13.85 726 972201 32267 55286873
Anaphylactoid reaction 19.56 13.85 19 972908 3487 55315653
Feeling drunk 19.53 13.85 22 972905 3770 55315370
Retinal toxicity 19.49 13.85 55 972872 1141 55317999
Transaminases abnormal 19.48 13.85 36 972891 557 55318583
Lymph node pain 19.47 13.85 59 972868 1276 55317864
Nephrotic syndrome 19.30 13.85 39 972888 5261 55313879
Renal artery stenosis 19.25 13.85 4 972923 1819 55317321
Hepatorenal syndrome 19.21 13.85 4 972923 1816 55317324
Miliaria 19.13 13.85 50 972877 990 55318150
Meningitis aseptic 19.08 13.85 29 972898 4370 55314770
Angle closure glaucoma 19.08 13.85 6 972921 2065 55317075
Right ventricular dysfunction 19.06 13.85 3 972924 1666 55317474
Portal vein thrombosis 19.04 13.85 9 972918 2414 55316726
Spinal nerve stimulator implantation 19.01 13.85 15 972912 86 55319054
Defaecation urgency 18.98 13.85 18 972909 3341 55315799
Maternal exposure during breast feeding 18.95 13.85 21 972906 3626 55315514
Cerebrovascular disorder 18.94 13.85 11 972916 2626 55316514
Blood glucose fluctuation 18.93 13.85 28 972899 4267 55314873
Rocky mountain spotted fever 18.93 13.85 10 972917 24 55319116
Product administered to patient of inappropriate age 18.92 13.85 13 972914 2835 55316305
Staphylococcal infection 18.89 13.85 813 972114 36805 55282335
Listless 18.88 13.85 11 972916 2621 55316519
Sudden cardiac death 18.83 13.85 6 972921 2048 55317092
Paradoxical drug reaction 18.77 13.85 23 972904 3797 55315343
Aphthous ulcer 18.74 13.85 126 972801 11893 55307247
Angiopathy 18.67 13.85 28 972899 4242 55314898
Synovectomy 18.58 13.85 19 972908 160 55318980
Gastrointestinal motility disorder 18.57 13.85 33 972894 4673 55314467
Amyotrophic lateral sclerosis 18.51 13.85 52 972875 1076 55318064
Prothrombin time shortened 18.50 13.85 4 972923 1769 55317371
Eructation 18.49 13.85 68 972859 7520 55311620
Electric shock 18.48 13.85 51 972876 1044 55318096
Varices oesophageal 18.47 13.85 14 972913 2902 55316238
Pharyngeal operation 18.45 13.85 6 972921 0 55319140
Compartment syndrome 18.40 13.85 6 972921 2018 55317122
High density lipoprotein decreased 18.33 13.85 4 972923 1758 55317382
Oral herpes 18.33 13.85 522 972405 22368 55296772
Anal haemorrhage 18.33 13.85 5 972922 1888 55317252
Vascular access complication 18.29 13.85 68 972859 1639 55317501
Spinal stenosis 18.21 13.85 342 972585 13672 55305468
Hypertensive emergency 18.19 13.85 3 972924 1610 55317530
X-ray abnormal 18.17 13.85 133 972794 4208 55314932
Facial paralysis 18.13 13.85 145 972782 13166 55305974
Sputum increased 18.11 13.85 7 972920 2117 55317023
Prescribed underdose 18.10 13.85 249 972678 20368 55298772
Stem cell transplant 18.06 13.85 4 972923 1740 55317400
Dizziness postural 18.05 13.85 55 972872 6443 55312697
Polyhydramnios 17.99 13.85 7 972920 2108 55317032
Diabetic neuropathy 17.96 13.85 23 972904 3725 55315415
Chronic sinusitis 17.94 13.85 79 972848 8299 55310841
Product use complaint 17.90 13.85 7 972920 2102 55317038
Rash pustular 17.86 13.85 185 972742 6478 55312662
Malignant neoplasm of conjunctiva 17.85 13.85 11 972916 39 55319101
BK virus infection 17.81 13.85 16 972911 3048 55316092
Duodenal ulcer perforation 17.81 13.85 1392 971535 66950 55252190
Cor pulmonale 17.79 13.85 6 972921 1975 55317165
Neuralgia 17.77 13.85 295 972632 23400 55295740
Catheterisation cardiac 17.77 13.85 29 972898 4246 55314894
Injection site streaking 17.64 13.85 10 972917 29 55319111
Gastrointestinal stoma complication 17.61 13.85 3 972924 1572 55317568
Decreased interest 17.59 13.85 16 972911 3030 55316110
Lower respiratory tract infection viral 17.56 13.85 42 972885 785 55318355
Hearing aid user 17.55 13.85 12 972915 53 55319087
Liver injury 17.54 13.85 570 972357 41278 55277862
Night sweats 17.53 13.85 876 972051 40337 55278803
Coronavirus infection 17.49 13.85 19 972908 3310 55315830
Infiltration anaesthesia 17.47 13.85 19 972908 173 55318967
Red blood cell sedimentation rate 17.47 13.85 131 972796 4177 55314963
Dermatitis exfoliative generalised 17.44 13.85 20 972907 3400 55315740
Kyphosis 17.41 13.85 9 972918 2293 55316847
Infected bite 17.41 13.85 66 972861 1606 55317534
Pelvic inflammatory disease 17.39 13.85 3 972924 1558 55317582
Abdominal adhesions 17.38 13.85 15 972912 2914 55316226
Glaucoma 17.33 13.85 407 972520 16922 55302218
Rhonchi 17.31 13.85 10 972917 2394 55316746
Oesophageal ulcer 17.27 13.85 28 972899 4111 55315029
Incorrect dosage administered 17.26 13.85 69 972858 1722 55317418
Discontinued product administered 17.26 13.85 11 972916 42 55319098
Mouth haemorrhage 17.20 13.85 55 972872 6346 55312794
Peripheral motor neuropathy 17.19 13.85 3 972924 1545 55317595
Staphylococcal skin infection 17.19 13.85 43 972884 828 55318312
Emotional disorder 17.18 13.85 133 972794 12162 55306978
Maternal exposure during pregnancy 17.17 13.85 2947 969980 186606 55132534
Hepatitis B virus test positive 17.15 13.85 20 972907 198 55318942
Hepatosplenic T-cell lymphoma 17.14 13.85 35 972892 585 55318555
Bile duct stone 17.14 13.85 20 972907 3374 55315766
Pregnancy 17.11 13.85 437 972490 32596 55286544
Hepatocellular carcinoma 17.11 13.85 10 972917 2379 55316761
SARS-CoV-2 test positive 17.10 13.85 53 972874 6176 55312964
Tenderness 17.09 13.85 463 972464 19692 55299448
Peripheral arterial occlusive disease 17.07 13.85 25 972902 3825 55315315
Quadriparesis 17.03 13.85 5 972922 1799 55317341
Intra-abdominal haematoma 17.02 13.85 4 972923 1670 55317470
Bite 17.01 13.85 28 972899 393 55318747
Hysterectomy 17.00 13.85 225 972702 8366 55310774
Butterfly rash 16.98 13.85 61 972866 1445 55317695
Bacterial sepsis 16.96 13.85 24 972903 3725 55315415
Trismus 16.88 13.85 22 972905 3536 55315604
Bone disorder 16.87 13.85 450 972477 19093 55300047
Carbon dioxide decreased 16.81 13.85 6 972921 1906 55317234
Type IV hypersensitivity reaction 16.79 13.85 12 972915 2564 55316576
Rheumatic fever 16.78 13.85 633 972294 28194 55290946
Mucosal disorder 16.75 13.85 7 972920 2019 55317121
Dermatitis psoriasiform 16.74 13.85 70 972857 1784 55317356
Hypersomnia 16.72 13.85 191 972736 16150 55302990
Nephrogenic anaemia 16.70 13.85 6 972921 1898 55317242
Gestational diabetes 16.69 13.85 77 972850 7987 55311153
Psychogenic seizure 16.65 13.85 4 972923 1645 55317495
Sunburn 16.62 13.85 88 972839 2480 55316660
Acinetobacter infection 16.61 13.85 3 972924 1507 55317633
Abdominal abscess 16.59 13.85 29 972898 4133 55315007
Blood urine present 16.52 13.85 152 972775 13403 55305737
Pneumonia influenzal 16.52 13.85 3 972924 1501 55317639
Multiple injuries 16.48 13.85 5 972922 1761 55317379
Product taste abnormal 16.47 13.85 6 972921 1882 55317258
Poor quality sleep 16.47 13.85 212 972715 17543 55301597
Enteritis infectious 16.44 13.85 7 972920 1997 55317143
Pulmonary sarcoidosis 16.43 13.85 45 972882 917 55318223
Blood creatinine decreased 16.38 13.85 41 972886 5125 55314015
Injection site hyperaesthesia 16.35 13.85 11 972916 47 55319093
Laryngeal disorder 16.28 13.85 45 972882 922 55318218
Conjunctival hyperaemia 16.27 13.85 9 972918 2207 55316933
Weight bearing difficulty 16.23 13.85 84 972843 2346 55316794
Neoplasm malignant 16.21 13.85 596 972331 26459 55292681
Tinea pedis 16.21 13.85 55 972872 1265 55317875
Mole excision 16.17 13.85 16 972911 129 55319011
Oropharyngeal discomfort 16.17 13.85 33 972894 4435 55314705
Liver abscess 16.13 13.85 14 972913 2712 55316428
Infected cyst 16.11 13.85 44 972883 895 55318245
Sputum culture positive 16.09 13.85 5 972922 1734 55317406
Intentional dose omission 16.07 13.85 169 972758 5941 55313199
Osteomyelitis 16.07 13.85 310 972617 24036 55295104
Spinal laminectomy 16.02 13.85 36 972891 645 55318495
Splenic infarction 15.95 13.85 4 972923 1598 55317542
Immunosuppression 15.94 13.85 209 972718 7755 55311385
Extradural haematoma 15.92 13.85 4 972923 1596 55317544
Staphylococcal sepsis 15.91 13.85 69 972858 7280 55311860
Mean cell haemoglobin increased 15.88 13.85 11 972916 2389 55316751
Red blood cell sedimentation rate decreased 15.86 13.85 17 972910 152 55318988
Seronegative arthritis 15.86 13.85 91 972836 2645 55316495
Apraxia 15.80 13.85 5 972922 1714 55317426
Hair colour changes 15.79 13.85 16 972911 2879 55316261
Metastases to spine 15.77 13.85 17 972910 2972 55316168
Premature rupture of membranes 15.75 13.85 37 972890 4728 55314412
Folate deficiency 15.75 13.85 9 972918 2168 55316972
Pelvic venous thrombosis 15.71 13.85 3 972924 1448 55317692
Asthmatic crisis 15.67 13.85 5 972922 1705 55317435
Talipes 15.57 13.85 3 972924 1439 55317701
Type I hypersensitivity 15.56 13.85 12 972915 2466 55316674
Vocal cord paralysis 15.52 13.85 7 972920 1930 55317210
Peripheral vascular disorder 15.51 13.85 49 972878 5676 55313464
Vascular pseudoaneurysm 15.51 13.85 3 972924 1435 55317705
Intentional underdose 15.50 13.85 5 972922 1693 55317447
False positive tuberculosis test 15.49 13.85 7 972920 10 55319130
Spinal fusion acquired 15.49 13.85 7 972920 10 55319130
Ligament operation 15.48 13.85 8 972919 18 55319122
Colitis microscopic 15.48 13.85 206 972721 7669 55311471
Dyspareunia 15.44 13.85 10 972917 2250 55316890
Vitamin B12 deficiency 15.43 13.85 33 972894 4360 55314780
Bipolar I disorder 15.38 13.85 5 972922 1685 55317455
Smear cervix 15.38 13.85 5 972922 0 55319140
Infected bunion 15.38 13.85 5 972922 0 55319140
Strabismus 15.37 13.85 7 972920 1919 55317221
Device allergy 15.35 13.85 10 972917 40 55319100
Anticonvulsant drug level increased 15.25 13.85 3 972924 1418 55317722
Device alarm issue 15.25 13.85 3 972924 1418 55317722
Parosmia 15.24 13.85 37 972890 4674 55314466
Cerebral venous thrombosis 15.20 13.85 7 972920 1906 55317234
Rash macular 15.18 13.85 465 972462 20139 55299001
Expired product administered 15.14 13.85 48 972879 5554 55313586
Chorea 15.12 13.85 3 972924 1409 55317731
Food allergy 15.04 13.85 90 972837 8734 55310406
Suicidal behaviour 15.00 13.85 12 972915 2421 55316719
Enterocolitis haemorrhagic 14.95 13.85 3 972924 1398 55317742
Cutaneous T-cell lymphoma 14.92 13.85 55 972872 1320 55317820
Bone sequestrum 14.89 13.85 3 972924 1394 55317746
Ulcer 14.88 13.85 501 972426 21984 55297156
Muscle atrophy 14.88 13.85 60 972867 6461 55312679
Therapy change 14.85 13.85 47 972880 5441 55313699
Lip ulceration 14.84 13.85 68 972859 1805 55317335
Hyporeflexia 14.83 13.85 6 972921 1765 55317375
Cytomegalovirus colitis 14.77 13.85 9 972918 2093 55317047
Mallory-Weiss syndrome 14.74 13.85 3 972924 1384 55317756
Spinal meningioma benign 14.71 13.85 14 972913 107 55319033
Oesophageal spasm 14.71 13.85 16 972911 2786 55316354
Hiccups 14.70 13.85 8 972919 1980 55317160
Salivary gland disorder 14.68 13.85 17 972910 167 55318973
Gastrointestinal inflammation 14.65 13.85 41 972886 4937 55314203
Hyperparathyroidism secondary 14.62 13.85 3 972924 1376 55317764
Sternal fracture 14.62 13.85 9 972918 2081 55317059
Throat irritation 14.59 13.85 698 972229 31985 55287155
Respiratory symptom 14.57 13.85 16 972911 2774 55316366
Anorectal discomfort 14.57 13.85 11 972916 2285 55316855
Dry eye 14.54 13.85 756 972171 34960 55284180
Interstitial lung disease 14.52 13.85 822 972105 56241 55262899
Concomitant disease progression 14.51 13.85 9 972918 2073 55317067
Menstruation irregular 14.50 13.85 59 972868 6337 55312803
Hepatic pain 14.49 13.85 17 972910 2861 55316279
Psychotic symptom 14.47 13.85 3 972924 1366 55317774
Femur fracture 14.45 13.85 544 972383 38751 55280389
Musculoskeletal injury 14.42 13.85 14 972913 110 55319030
Gingival injury 14.41 13.85 8 972919 22 55319118
Application site vesicles 14.41 13.85 3 972924 1362 55317778
Myoglobin blood increased 14.39 13.85 3 972924 1361 55317779
Meniscus operation 14.35 13.85 15 972912 130 55319010
Metastatic bronchial carcinoma 14.35 13.85 15 972912 130 55319010
Optic neuropathy 14.33 13.85 8 972919 1952 55317188
In vitro fertilisation 14.31 13.85 12 972915 76 55319064
Intracardiac thrombus 14.31 13.85 11 972916 2264 55316876
Anticipatory anxiety 14.22 13.85 45 972882 997 55318143
Congenital anomaly 14.20 13.85 5 972922 1602 55317538
Localised oedema 14.20 13.85 42 972885 4967 55314173
Antibody test positive 14.19 13.85 81 972846 2350 55316790
Thoracic vertebral fracture 14.17 13.85 33 972894 4230 55314910
Hypercoagulation 14.17 13.85 8 972919 1940 55317200
Impaired quality of life 14.15 13.85 87 972840 8387 55310753
Jaw disorder 14.13 13.85 43 972884 5040 55314100
Intervertebral discitis 14.13 13.85 90 972837 2717 55316423
Tooth fracture 14.13 13.85 253 972674 10023 55309117
Hepatitis E 14.10 13.85 3 972924 1342 55317798
Soft tissue injury 14.09 13.85 5 972922 1594 55317546
Meningitis staphylococcal 14.08 13.85 7 972920 14 55319126
Mean platelet volume decreased 14.07 13.85 75 972852 2119 55317021
Recurrent cancer 14.05 13.85 7 972920 1821 55317319
Ureteric obstruction 14.02 13.85 6 972921 1706 55317434
Pelvic fracture 14.02 13.85 139 972788 12074 55307066
Pneumocystis jirovecii pneumonia 14.01 13.85 189 972738 15512 55303628
Psychiatric decompensation 14.00 13.85 3 972924 1335 55317805
Intervertebral disc compression 13.97 13.85 43 972884 938 55318202
Focal segmental glomerulosclerosis 13.95 13.85 4 972923 1462 55317678
Vaginal operation 13.93 13.85 6 972921 7 55319133
Labelled drug-disease interaction medication error 13.92 13.85 15 972912 135 55319005
Faeces hard 13.91 13.85 7 972920 1811 55317329
Toxoplasmosis 13.90 13.85 4 972923 1458 55317682
Enterococcal sepsis 13.88 13.85 3 972924 1327 55317813
Platelet disorder 13.85 13.85 6 972921 1694 55317446

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Injection site pain 11203.39 14.20 5381 234201 29253 31428509
Psoriasis 9324.23 14.20 5250 234332 41469 31416293
Injection site erythema 7173.25 14.20 3033 236549 11429 31446333
Rheumatoid arthritis 5310.48 14.20 3708 235874 44101 31413661
Arthralgia 4675.32 14.20 5722 233860 145702 31312060
Drug ineffective 4620.92 14.20 9549 230033 386024 31071738
Injection site swelling 4383.49 14.20 1928 237654 8159 31449603
Injection site pruritus 3887.65 14.20 1539 238043 4655 31453107
Injection site reaction 3103.34 14.20 1590 237992 10061 31447701
Injection site bruising 2771.37 14.20 1305 238277 6670 31451092
Therapeutic product effect decreased 2705.58 14.20 2098 237484 29524 31428238
Joint swelling 2586.75 14.20 2563 237019 50868 31406894
Injection site haemorrhage 2577.26 14.20 1294 238288 7791 31449971
Wrong technique in product usage process 2522.61 14.20 2058 237524 31285 31426477
Therapeutic product effect incomplete 2482.65 14.20 2290 237292 41406 31416356
Nasopharyngitis 2390.20 14.20 2658 236924 60587 31397175
Pain in extremity 2138.86 14.20 3433 236149 112770 31344992
Pain 2024.65 14.20 4393 235189 182366 31275396
Accidental exposure to product 1979.81 14.20 1177 238405 10318 31447444
Product dose omission issue 1904.88 14.20 3092 236490 102494 31355268
Psoriatic arthropathy 1778.00 14.20 1355 238227 18528 31439234
Injection site warmth 1685.12 14.20 606 238976 1268 31456494
Musculoskeletal stiffness 1671.29 14.20 1801 237781 39524 31418238
Acute kidney injury 1546.63 14.20 161 239421 279553 31178209
Device issue 1495.55 14.20 882 238700 7602 31450160
Product storage error 1452.50 14.20 812 238770 6254 31451508
Injection site rash 1414.50 14.20 649 238933 3087 31454675
Mobility decreased 1271.00 14.20 1287 238295 26182 31431580
Drug interaction 1194.09 14.20 104 239478 208439 31249323
Toxicity to various agents 1187.04 14.20 42 239540 181445 31276317
Therapeutic response decreased 1146.79 14.20 1198 238384 25311 31432451
Sinusitis 1077.31 14.20 1357 238225 35339 31422423
Arthritis 1015.50 14.20 1141 238441 26244 31431518
Joint stiffness 1014.23 14.20 736 238846 9285 31448477
Hypotension 1000.79 14.20 172 239410 204446 31253316
Anaemia 935.89 14.20 232 239350 213290 31244472
Ankylosing spondylitis 916.49 14.20 565 239017 5316 31452446
Underdose 914.28 14.20 760 238822 11847 31445915
Musculoskeletal pain 854.66 14.20 1090 238492 28738 31429024
Treatment failure 831.01 14.20 1265 238317 39527 31418235
Death 830.74 14.20 904 238678 359665 31098097
Arthropathy 817.25 14.20 958 238624 23093 31434669
Skin plaque 788.77 14.20 448 239134 3567 31454195
Febrile neutropenia 760.30 14.20 39 239543 121810 31335952
Injection site mass 734.57 14.20 491 239091 5373 31452389
Injection site discomfort 700.67 14.20 297 239285 1120 31456642
Synovitis 681.32 14.20 636 238946 11647 31446115
Knee arthroplasty 673.44 14.20 486 239096 6072 31451690
Injection site discolouration 662.55 14.20 282 239300 1077 31456685
Swelling 660.61 14.20 1086 238496 36272 31421490
Injection site urticaria 653.68 14.20 299 239283 1409 31456353
Thrombocytopenia 624.98 14.20 155 239427 142592 31315170
Diarrhoea 595.09 14.20 1101 238481 351308 31106454
Completed suicide 594.78 14.20 22 239560 91492 31366270
Neutropenia 588.69 14.20 166 239416 140198 31317564
Drug abuse 584.90 14.20 17 239565 87741 31370021
Injection site induration 584.54 14.20 319 239263 2328 31455434
Confusional state 571.70 14.20 151 239431 133183 31324579
Injection site extravasation 552.82 14.20 306 239276 2304 31455458
Malignant neoplasm progression 546.93 14.20 10 239572 78988 31378774
Dyspnoea 526.56 14.20 1135 238447 342344 31115418
Vomiting 521.65 14.20 555 239027 223418 31234344
Contraindicated product administered 514.06 14.20 689 238893 19083 31438679
Peripheral swelling 489.37 14.20 1369 238213 66496 31391266
Influenza 485.55 14.20 1050 238532 43275 31414487
Hyponatraemia 468.54 14.20 21 239561 73778 31383984
Dehydration 466.77 14.20 159 239423 118952 31338810
Drug intolerance 457.06 14.20 1130 238452 50903 31406859
Hyperkalaemia 441.96 14.20 9 239573 64342 31393420
Constipation 441.95 14.20 192 239390 123799 31333963
Surgery 441.44 14.20 510 239072 12089 31445673
Rhabdomyolysis 436.24 14.20 9 239573 63572 31394190
Bradycardia 423.46 14.20 25 239557 69302 31388460
Decreased appetite 397.89 14.20 344 239238 152873 31304889
Respiratory tract congestion 393.49 14.20 329 239253 5168 31452594
General physical health deterioration 383.53 14.20 189 239393 113246 31344516
Respiratory failure 382.78 14.20 144 239438 101305 31356457
Cardiac arrest 381.27 14.20 101 239481 88961 31368801
Gastrointestinal haemorrhage 372.11 14.20 84 239498 82465 31375297
Disease progression 366.22 14.20 114 239468 90350 31367412
Therapy non-responder 365.68 14.20 797 238785 33014 31424748
Injection site haematoma 349.62 14.20 189 239393 1350 31456412
C-reactive protein abnormal 348.08 14.20 358 239224 7411 31450351
Bone erosion 346.64 14.20 251 239331 3152 31454610
Intentional product misuse 344.65 14.20 835 238747 37116 31420646
Tachycardia 344.58 14.20 77 239505 76130 31381632
Seizure 343.68 14.20 162 239420 99606 31358156
Blood creatinine increased 343.53 14.20 122 239460 88956 31368806
Hip arthroplasty 342.72 14.20 268 239314 3807 31453955
Overdose 335.06 14.20 111 239471 84553 31373209
Hypokalaemia 334.35 14.20 17 239565 53557 31404205
Back pain 327.20 14.20 1663 237919 107750 31350012
Syncope 326.20 14.20 118 239464 85064 31372698
Pancytopenia 322.62 14.20 128 239454 87188 31370574
Abdominal pain 321.41 14.20 378 239204 145574 31312188
Haemoglobin decreased 317.45 14.20 233 239349 112442 31345320
Headache 316.00 14.20 2421 237161 181231 31276531
Hypoglycaemia 315.31 14.20 17 239565 50929 31406833
Plasma cell myeloma 310.10 14.20 33 239549 56498 31401264
Pyrexia 307.91 14.20 1219 238363 302621 31155141
Platelet count decreased 305.15 14.20 233 239349 110202 31347560
Renal impairment 297.69 14.20 140 239442 86209 31371553
Apparent death 294.37 14.20 233 239349 3372 31454390
Atrial fibrillation 293.36 14.20 257 239325 113526 31344236
Cardio-respiratory arrest 289.42 14.20 28 239554 51698 31406064
Iritis 286.04 14.20 157 239425 1160 31456602
International normalised ratio increased 280.15 14.20 15 239567 45208 31412554
Oropharyngeal pain 277.64 14.20 685 238897 30798 31426964
Hypoxia 274.35 14.20 30 239552 50283 31407479
Intentional overdose 272.09 14.20 9 239573 41380 31416382
Agitation 272.08 14.20 42 239540 54127 31403635
Electrocardiogram QT prolonged 270.61 14.20 3 239579 37984 31419778
Neck pain 264.89 14.20 555 239027 22355 31435407
Condition aggravated 263.72 14.20 2129 237453 161880 31295882
Hand deformity 261.90 14.20 203 239379 2844 31454918
Neutrophil count decreased 259.86 14.20 25 239557 46369 31411393
Disability 259.66 14.20 242 239340 4419 31453343
Unevaluable event 258.85 14.20 655 238927 29920 31427842
Incorrect dose administered by device 253.95 14.20 158 239424 1512 31456250
Metabolic acidosis 251.98 14.20 11 239571 39566 31418196
Drug hypersensitivity 248.16 14.20 1147 238435 71452 31386310
Diverticulitis 245.76 14.20 477 239105 18168 31439594
Cardiac failure 245.60 14.20 175 239407 85778 31371984
Tuberculin test positive 244.03 14.20 134 239448 991 31456771
Product use in unapproved indication 242.55 14.20 235 239347 98936 31358826
Infection 234.11 14.20 1230 238352 80701 31377061
Sepsis 233.49 14.20 500 239082 151429 31306333
Foetal exposure during pregnancy 231.67 14.20 21 239561 40855 31416907
Hallucination 230.77 14.20 37 239545 46373 31411389
Delirium 230.20 14.20 23 239559 41398 31416364
Injection site vesicles 226.05 14.20 103 239479 480 31457282
Musculoskeletal disorder 225.93 14.20 247 239335 5497 31452265
Suicide attempt 222.70 14.20 15 239567 37233 31420529
Fall 222.64 14.20 695 238887 185394 31272368
Injection site irritation 221.40 14.20 125 239457 982 31456780
Somnolence 217.21 14.20 259 239323 99186 31358576
Multiple organ dysfunction syndrome 216.57 14.20 123 239459 68080 31389682
Blood pressure decreased 216.51 14.20 49 239533 48042 31409720
Grip strength decreased 213.86 14.20 170 239412 2476 31455286
Rhinorrhoea 212.79 14.20 510 239072 22502 31435260
Red blood cell sedimentation rate abnormal 212.42 14.20 179 239403 2843 31454919
Joint lock 212.11 14.20 124 239458 1048 31456714
Septic shock 209.09 14.20 120 239462 66038 31391724
Mental status changes 207.87 14.20 17 239565 35951 31421811
Localised infection 206.65 14.20 395 239187 14870 31442892
Lactic acidosis 206.25 14.20 8 239574 31929 31425833
Depressed level of consciousness 205.49 14.20 25 239557 38576 31419186
Melaena 204.87 14.20 10 239572 32644 31425118
Coma 204.16 14.20 33 239549 41117 31416645
Foot deformity 203.83 14.20 201 239381 3948 31453814
Herpes zoster 203.05 14.20 617 238965 31376 31426386
Sinus congestion 200.74 14.20 217 239365 4766 31452996
Red blood cell sedimentation rate increased 198.99 14.20 279 239303 8067 31449695
Nodule 198.72 14.20 230 239352 5460 31452302
Paranasal sinus hypersecretion 197.54 14.20 108 239474 791 31456971
Skin laceration 196.93 14.20 328 239254 11063 31446699
Oxygen saturation decreased 196.69 14.20 63 239519 49052 31408710
Joint range of motion decreased 196.27 14.20 247 239335 6414 31451348
Loss of consciousness 194.15 14.20 179 239403 77176 31380586
Inflammation 193.42 14.20 521 239061 24720 31433042
Pneumonia aspiration 192.25 14.20 31 239551 38695 31419067
Finger deformity 191.60 14.20 118 239464 1107 31456655
Blood creatine phosphokinase increased 190.49 14.20 42 239540 41932 31415830
Chondropathy 190.21 14.20 107 239475 834 31456928
Fear of injection 189.32 14.20 118 239464 1133 31456629
Hyperglycaemia 188.44 14.20 26 239556 36450 31421312
Aggression 187.05 14.20 29 239553 37262 31420500
Osteoarthritis 186.54 14.20 432 239150 18635 31439127
Feeling abnormal 184.06 14.20 886 238696 56116 31401646
Injury associated with device 183.72 14.20 103 239479 797 31456965
Hypersensitivity 181.12 14.20 868 238714 54875 31402887
Limb discomfort 179.70 14.20 297 239285 9952 31447810
Haematuria 175.79 14.20 65 239517 46249 31411513
Asthenia 175.28 14.20 990 238592 223765 31233997
Loss of personal independence in daily activities 175.26 14.20 541 239041 27747 31430015
Cardiac failure congestive 175.20 14.20 205 239377 79182 31378580
Acute myocardial infarction 172.63 14.20 84 239498 50739 31407023
Impaired work ability 171.69 14.20 217 239365 5660 31452102
Injection site macule 171.58 14.20 47 239535 13 31457749
Knee operation 170.11 14.20 124 239458 1574 31456188
Drug reaction with eosinophilia and systemic symptoms 168.55 14.20 16 239566 30002 31427760
Upper respiratory tract infection 167.93 14.20 547 239035 28875 31428887
Sleep disorder due to general medical condition, insomnia type 166.24 14.20 110 239472 1181 31456581
Respiratory distress 164.01 14.20 28 239554 33525 31424237
Dysphagia 163.95 14.20 118 239464 57558 31400204
Mycobacterium tuberculosis complex test positive 163.50 14.20 104 239478 1038 31456724
Sarcoidosis 161.88 14.20 147 239435 2592 31455170
Infusion related reaction 160.84 14.20 81 239501 47974 31409788
Weight decreased 158.78 14.20 646 238936 159306 31298456
Spinal operation 158.71 14.20 141 239441 2413 31455349
Urinary retention 158.70 14.20 31 239551 33694 31424068
Unresponsive to stimuli 158.40 14.20 9 239573 25791 31431971
Shoulder operation 157.72 14.20 95 239487 853 31456909
Cerebral haemorrhage 156.87 14.20 29 239553 32783 31424979
Orthostatic hypotension 155.88 14.20 6 239576 24113 31433649
Musculoskeletal discomfort 153.10 14.20 225 239357 6798 31450964
Uveitis 152.40 14.20 221 239361 6595 31451167
Spinal fusion surgery 152.11 14.20 91 239491 806 31456956
Blood bilirubin increased 149.96 14.20 40 239542 35096 31422666
Nausea 149.49 14.20 1548 238034 306399 31151363
Lymphoma 147.91 14.20 283 239299 10660 31447102
Therapeutic product effect delayed 145.82 14.20 98 239484 1082 31456680
Chronic kidney disease 144.61 14.20 53 239529 37922 31419840
Injection site recall reaction 144.03 14.20 37 239545 0 31457762
Renal failure 142.85 14.20 467 239115 122863 31334899
Pleural effusion 141.39 14.20 217 239365 74703 31383059
Impaired healing 141.33 14.20 323 239259 13809 31443953
Therapy cessation 139.53 14.20 334 239248 14721 31443041
Coronary artery disease 139.41 14.20 88 239494 45999 31411763
Blood glucose increased 138.81 14.20 154 239428 60929 31396833
Mucosal inflammation 138.11 14.20 44 239538 34383 31423379
Haematemesis 138.05 14.20 16 239566 25637 31432125
Bone marrow failure 137.72 14.20 23 239559 27985 31429777
Inappropriate schedule of product administration 136.89 14.20 751 238831 50072 31407690
Haemorrhage 135.62 14.20 96 239486 47238 31410524
Neoplasm progression 134.69 14.20 4 239578 20268 31437494
Ill-defined disorder 134.22 14.20 295 239287 12282 31445480
Blood urea increased 133.73 14.20 28 239554 28984 31428778
Skin haemorrhage 133.42 14.20 158 239424 3846 31453916
Ascites 133 14.20 72 239510 40941 31416821
Joint noise 132.04 14.20 71 239511 501 31457261
Oedema 131.89 14.20 79 239503 42482 31415280
Drug dose omission by device 131.22 14.20 100 239482 1364 31456398
Encephalopathy 131.17 14.20 41 239541 32433 31425329
Iridocyclitis 131.05 14.20 102 239480 1438 31456324
Nasal congestion 130.17 14.20 394 239188 19987 31437775
Blood pressure increased 129.88 14.20 253 239329 79380 31378382
Agranulocytosis 128.65 14.20 8 239574 21239 31436523
Drug level increased 127.20 14.20 6 239576 20180 31437582
Haematocrit decreased 126.82 14.20 35 239547 30026 31427736
Pulmonary oedema 126.52 14.20 91 239491 44411 31413351
Cardiogenic shock 125.66 14.20 12 239570 22396 31435366
Neuropathy peripheral 125.41 14.20 238 239344 75411 31382351
Therapy interrupted 125.14 14.20 259 239323 10337 31447425
Cholestasis 124.61 14.20 20 239562 25055 31432707
Hypoacusis 124.48 14.20 319 239263 14680 31443082
Arthropod bite 124.23 14.20 123 239459 2428 31455334
Hypervolaemia 123.50 14.20 3 239579 18248 31439514
Joint destruction 122.38 14.20 56 239526 264 31457498
Tooth infection 122.05 14.20 187 239395 5867 31451895
Sedation 121.61 14.20 5 239577 18960 31438802
Mass 121.27 14.20 207 239375 7124 31450638
Hepatic failure 118.96 14.20 49 239533 32653 31425109
Decreased immune responsiveness 118.58 14.20 95 239487 1400 31456362
Abnormal behaviour 118.42 14.20 19 239563 23809 31433953
Dysarthria 118.06 14.20 47 239535 31970 31425792
Leukopenia 116.46 14.20 160 239422 57668 31400094
Joint effusion 116.02 14.20 158 239424 4441 31453321
Lymphocyte count decreased 115.94 14.20 11 239571 20638 31437124
Hypocalcaemia 115.10 14.20 15 239567 21963 31435799
Psychotic disorder 114.88 14.20 16 239566 22277 31435485
Sneezing 114.80 14.20 160 239422 4599 31453163
Rash maculo-papular 114.15 14.20 27 239555 25692 31432070
Drug withdrawal syndrome 113.70 14.20 7 239575 18743 31439019
Device difficult to use 113.46 14.20 104 239478 1857 31455905
Bronchitis 113.03 14.20 585 238997 38132 31419630
Blood alkaline phosphatase increased 112.32 14.20 41 239541 29412 31428350
Respiratory arrest 111.84 14.20 30 239552 26227 31431535
Device malfunction 111.20 14.20 228 239354 9038 31448724
White blood cell count decreased 111.09 14.20 317 239265 87081 31370681
Toxic epidermal necrolysis 110.69 14.20 10 239572 19514 31438248
Shock 110.44 14.20 19 239563 22626 31435136
Pharyngitis streptococcal 110.40 14.20 109 239473 2144 31455618
Pneumonia 110.19 14.20 1828 237754 333484 31124278
Upper gastrointestinal haemorrhage 109.72 14.20 21 239561 23162 31434600
Suicidal ideation 109.44 14.20 70 239512 36336 31421426
Heart rate increased 109.31 14.20 90 239492 41020 31416742
Adverse event 108.62 14.20 325 239257 16380 31441382
Sinus disorder 108.45 14.20 181 239401 6114 31451648
Gait disturbance 108.39 14.20 976 238606 76519 31381243
Furuncle 108.19 14.20 125 239457 2961 31454801
Adverse reaction 108.10 14.20 121 239461 2766 31454996
Anaphylactic reaction 107.96 14.20 44 239538 29509 31428253
Shoulder arthroplasty 107.66 14.20 58 239524 411 31457351
Dizziness 104.82 14.20 981 238601 198166 31259596
Disorientation 104.10 14.20 51 239531 30693 31427069
Ear infection 103.61 14.20 216 239366 8665 31449097
Pneumonitis 103.56 14.20 51 239531 30601 31427161
Heart rate decreased 103.39 14.20 42 239540 28224 31429538
Skin exfoliation 102.97 14.20 405 239177 23469 31434293
Tumour lysis syndrome 102.34 14.20 3 239579 15382 31442380
Chest pain 102.27 14.20 495 239087 116462 31341300
Extra dose administered 101.63 14.20 127 239455 3273 31454489
Jaundice 101.41 14.20 51 239531 30236 31427526
Foot operation 100.81 14.20 63 239519 608 31457154
Diabetic ketoacidosis 100.48 14.20 7 239575 16898 31440864
Injection site injury 100.43 14.20 45 239537 200 31457562
Pancreatitis acute 100.43 14.20 34 239548 25566 31432196
Eosinophilia 100.12 14.20 26 239556 23227 31434535
Tooth fracture 99.66 14.20 125 239457 3234 31454528
Palmar-plantar erythrodysaesthesia syndrome 99.55 14.20 4 239578 15479 31442283
Ventricular tachycardia 99.22 14.20 28 239554 23673 31434089
Hypoaesthesia 98.43 14.20 743 238839 55279 31402483
Abdominal distension 98.31 14.20 144 239438 50540 31407222
Sinus headache 97.81 14.20 71 239511 895 31456867
Altered state of consciousness 97.68 14.20 20 239562 21031 31436731
Joint arthroplasty 97.65 14.20 66 239516 736 31457026
Demyelination 97.46 14.20 116 239466 2839 31454923
Dyspnoea exertional 97.23 14.20 90 239492 38747 31419015
Wheezing 96.65 14.20 78 239504 35908 31421854
Angioedema 96.53 14.20 68 239514 33550 31424212
Tubulointerstitial nephritis 95.96 14.20 13 239569 18483 31439279
Rheumatoid factor negative 95.88 14.20 67 239515 792 31456970
Synovial cyst 95.83 14.20 97 239485 1968 31455794
Circulatory collapse 95.34 14.20 17 239565 19727 31438035
Arrhythmia 94.85 14.20 67 239515 33010 31424752
Dyskinesia 94.70 14.20 21 239561 20889 31436873
Tachypnoea 94.65 14.20 8 239574 16475 31441287
Gamma-glutamyltransferase increased 94.45 14.20 46 239536 27779 31429983
Erythema 94.37 14.20 976 238606 79429 31378333
Scratch 93.99 14.20 114 239468 2847 31454915
Injection site papule 92.88 14.20 46 239536 267 31457495
Acute respiratory failure 92.80 14.20 48 239534 28007 31429755
Bone cyst 92.56 14.20 74 239508 1087 31456675
Restlessness 91.69 14.20 31 239551 23330 31434432
Haemoptysis 91.26 14.20 66 239516 32123 31425639
Blood lactate dehydrogenase increased 90.96 14.20 21 239561 20318 31437444
Subdural haematoma 90.17 14.20 17 239565 18954 31438808
Sinus tachycardia 90.17 14.20 8 239574 15841 31441921
Urticaria 90.15 14.20 743 238839 56774 31400988
Hallucination, visual 89.78 14.20 8 239574 15786 31441976
Generalised tonic-clonic seizure 88.30 14.20 21 239561 19910 31437852
Injection site inflammation 87.82 14.20 59 239523 651 31457111
Aspartate aminotransferase increased 87.63 14.20 217 239365 62502 31395260
Acute respiratory distress syndrome 87.29 14.20 38 239544 24502 31433260
Pulmonary hypertension 87.07 14.20 22 239560 20019 31437743
Influenza like illness 86.87 14.20 402 239180 25035 31432727
Onychoclasis 86.39 14.20 86 239496 1709 31456053
Myoclonus 85.51 14.20 5 239577 13985 31443777
Ventricular fibrillation 85.22 14.20 19 239563 18829 31438933
Renal tubular necrosis 85.20 14.20 7 239575 14752 31443010
Cough 85.18 14.20 1462 238120 133352 31324410
Contusion 84.87 14.20 482 239100 32546 31425216
Drug-induced liver injury 84.66 14.20 39 239543 24324 31433438
Hyperbilirubinaemia 84.30 14.20 10 239572 15740 31442022
Osteonecrosis of jaw 83.96 14.20 14 239568 17057 31440705
Anti-cyclic citrullinated peptide antibody positive 83.51 14.20 76 239506 1344 31456418
Cognitive disorder 83.39 14.20 42 239540 24881 31432881
Urinary tract infection 82.88 14.20 300 239282 76569 31381193
Nail disorder 82.49 14.20 86 239496 1809 31455953
Leukocytosis 82.29 14.20 32 239550 22082 31435680
Juvenile idiopathic arthritis 81.51 14.20 82 239500 1651 31456111
Myelosuppression 81.04 14.20 9 239573 14911 31442851
Cerebral infarction 80.78 14.20 48 239534 25929 31431833
Sensitivity to weather change 79.90 14.20 76 239506 1425 31456337
Haemorrhage intracranial 79.72 14.20 10 239572 15078 31442684
COVID-19 79.49 14.20 186 239396 54635 31403127
Nerve compression 79.36 14.20 104 239478 2814 31454948
Joint warmth 78.44 14.20 41 239541 271 31457491
Intentional self-injury 77.74 14.20 6 239576 13309 31444453
Epilepsy 77.38 14.20 31 239551 21010 31436752
Acne cystic 76.91 14.20 48 239534 462 31457300
Exostosis 76.88 14.20 119 239463 3767 31453995
Rheumatoid nodule 76.74 14.20 98 239484 2583 31455179
Tremor 76.73 14.20 307 239275 76113 31381649
Intentional product use issue 75.98 14.20 162 239420 49185 31408577
Dislocation of vertebra 75.93 14.20 45 239537 391 31457371
Rectal haemorrhage 75.56 14.20 98 239484 36206 31421556
Enthesopathy 74.83 14.20 124 239458 4163 31453599
Tuberculosis 74.02 14.20 182 239400 8159 31449603
Circumstance or information capable of leading to medication error 73.85 14.20 75 239507 1528 31456234
Tenderness 73.67 14.20 148 239434 5780 31451982
Urinary incontinence 73.36 14.20 20 239562 17300 31440462
Device use error 73.29 14.20 87 239495 2123 31455639
Accidental overdose 72.62 14.20 24 239558 18326 31439436
Alanine aminotransferase abnormal 72.30 14.20 117 239465 3850 31453912
Joint ankylosis 71.88 14.20 62 239520 1018 31456744
Atlantoaxial instability 71.83 14.20 40 239542 305 31457457
Injection site paraesthesia 71.19 14.20 30 239552 111 31457651
Alanine aminotransferase increased 71.16 14.20 306 239276 74350 31383412
Malaise 71.11 14.20 1721 237861 166790 31290972
Treatment noncompliance 71.08 14.20 54 239528 25630 31432132
Small intestinal obstruction 71.01 14.20 9 239573 13463 31444299
Medication error 70.91 14.20 42 239540 22730 31435032
Full blood count decreased 70.24 14.20 19 239563 16521 31441241
Coagulopathy 70.21 14.20 26 239556 18489 31439273
Joint fluid drainage 70.04 14.20 27 239555 74 31457688
Stevens-Johnson syndrome 70.03 14.20 22 239560 17350 31440412
Chondrolysis 69.86 14.20 28 239554 88 31457674
Spinal instability 69.73 14.20 40 239542 325 31457437
Hypophagia 69.57 14.20 40 239542 22002 31435760
Mineral metabolism disorder 69.02 14.20 40 239542 332 31457430
Pancreatitis 69.00 14.20 102 239480 35669 31422093
Neutropenic sepsis 68.43 14.20 7 239575 12372 31445390
Intervertebral disc space narrowing 68.22 14.20 57 239525 894 31456868
Disseminated intravascular coagulation 68.12 14.20 35 239547 20502 31437260
Hepatic encephalopathy 67.71 14.20 11 239571 13660 31444102
Fluid retention 67.55 14.20 53 239529 24749 31433013
Pallor 67.55 14.20 43 239539 22381 31435381
Wrist deformity 67.06 14.20 39 239543 326 31457436
Cytomegalovirus infection 67.03 14.20 53 239529 24654 31433108
Drug eruption 67.02 14.20 294 239288 17893 31439869
Acute hepatic failure 66.80 14.20 9 239573 12850 31444912
Nephropathy toxic 66.61 14.20 5 239577 11348 31446414
Cyanosis 66.55 14.20 6 239576 11729 31446033
Haematoma 66.48 14.20 51 239531 24088 31433674
Immune system disorder 66.43 14.20 121 239461 4387 31453375
Upper respiratory tract congestion 66.23 14.20 51 239531 707 31457055
Blood sodium decreased 66.17 14.20 17 239565 15298 31442464
Rotator cuff repair 66.14 14.20 36 239546 261 31457501
Limb operation 66.13 14.20 48 239534 605 31457157
Clostridium difficile colitis 65.95 14.20 13 239569 14043 31443719
Poisoning 65.76 14.20 3 239579 10388 31447374
Ileus 65.23 14.20 17 239565 15152 31442610
Neutrophil count increased 65.08 14.20 19 239563 15712 31442050
Anxiety 64.93 14.20 412 239170 90621 31367141
Spinal pain 64.92 14.20 130 239452 5065 31452697
Red blood cell count decreased 64.90 14.20 64 239518 26743 31431019
Angina pectoris 64.85 14.20 77 239505 29564 31428198
Blood potassium decreased 64.11 14.20 22 239560 16404 31441358
Corrective lens user 63.66 14.20 23 239559 49 31457713
Therapeutic response delayed 63.14 14.20 43 239539 486 31457276
Adrenal insufficiency 63.11 14.20 10 239572 12649 31445113
Hepatocellular injury 62.61 14.20 43 239539 21501 31436261
Palpitations 62.52 14.20 103 239479 34480 31423282
Latent tuberculosis 61.43 14.20 60 239522 1164 31456598
Intestinal obstruction 61.43 14.20 40 239542 20570 31437192
Joint injury 61.20 14.20 163 239419 7678 31450084
Ischaemic stroke 60.80 14.20 26 239556 16945 31440817
Tenosynovitis 60.77 14.20 112 239470 4098 31453664
Skin discolouration 60.38 14.20 264 239318 16043 31441719
Aphasia 60.33 14.20 38 239544 19893 31437869
White blood cell count increased 60.06 14.20 128 239454 38872 31418890
Intervertebral disc protrusion 60.06 14.20 178 239404 8922 31448840
Brain oedema 59.93 14.20 12 239570 12820 31444942
Troponin increased 59.85 14.20 4 239578 9998 31447764
Electrolyte imbalance 59.66 14.20 10 239572 12138 31445624
Speech disorder 59.49 14.20 57 239525 24144 31433618
Myocardial ischaemia 58.97 14.20 26 239556 16641 31441121
Tooth extraction 58.94 14.20 113 239469 4262 31453500
Hypertension 58.62 14.20 652 238930 127448 31330314
Cerebrovascular accident 58.61 14.20 356 239226 79128 31378634
Tooth disorder 58.59 14.20 188 239394 9841 31447921
Pulmonary arterial hypertension 58.56 14.20 4 239578 9817 31447945
Anuria 58.51 14.20 4 239578 9810 31447952
Atrial flutter 58.29 14.20 19 239563 14636 31443126
Throat irritation 57.54 14.20 178 239404 9136 31448626
Blood potassium increased 57.43 14.20 22 239560 15323 31442439
Endodontic procedure 57.29 14.20 36 239546 351 31457411
No adverse event 57.26 14.20 39 239543 19586 31438176
Oral surgery 57.23 14.20 42 239540 539 31457223
Flushing 57.05 14.20 87 239495 30041 31427721
Drug tolerance decreased 57.05 14.20 69 239513 1718 31456044
Antibiotic therapy 56.54 14.20 21 239561 50 31457712
Blood pressure fluctuation 56.53 14.20 53 239529 22683 31435079
Delusion 56.49 14.20 11 239571 11986 31445776
Increased tendency to bruise 56.48 14.20 100 239482 3545 31454217
Muscle rigidity 56.29 14.20 5 239577 9892 31447870
Skin disorder 55.94 14.20 212 239370 12069 31445693
Sudden death 55.33 14.20 20 239562 14437 31443325
Presyncope 55.32 14.20 31 239551 17297 31440465
Pruritus 55.08 14.20 1286 238296 123881 31333881
Hallucination, auditory 54.41 14.20 7 239575 10353 31447409
Skin ulcer 54.22 14.20 296 239286 19689 31438073
Rheumatoid factor increased 54.21 14.20 40 239542 518 31457244
Renal injury 54.14 14.20 8 239574 10657 31447105
Prescribed overdose 54.07 14.20 4 239578 9188 31448574
Skin fissures 54.01 14.20 109 239473 4271 31453491
Face oedema 53.81 14.20 8 239574 10608 31447154
Hypothermia 53.80 14.20 5 239577 9539 31448223
Myocarditis 53.79 14.20 12 239570 11888 31445874
Acute coronary syndrome 53.73 14.20 15 239567 12774 31444988
Pathogen resistance 53.51 14.20 3 239579 8698 31449064
Cardiomegaly 53.46 14.20 21 239561 14404 31443358
Malignant melanoma 53.02 14.20 153 239429 7554 31450208
Haemodynamic instability 52.60 14.20 3 239579 8572 31449190
Physical disability 51.79 14.20 57 239525 1278 31456484
Anaphylactic shock 51.75 14.20 21 239561 14124 31443638
Atelectasis 51.63 14.20 29 239553 16160 31441602
Glomerular filtration rate decreased 51.59 14.20 13 239569 11852 31445910
Meniscus injury 51.54 14.20 70 239512 1962 31455800
Cardiac operation 51.33 14.20 83 239499 2729 31455033
Malnutrition 51.13 14.20 12 239570 11481 31446281
COVID-19 pneumonia 51.06 14.20 16 239566 12639 31445123
Vein rupture 51.03 14.20 44 239538 722 31457040
Urine output decreased 50.82 14.20 6 239576 9480 31448282
Skin mass 50.73 14.20 95 239487 3519 31454243
Prostate cancer 50.71 14.20 470 239112 37131 31420631
Prostate infection 50.65 14.20 46 239536 811 31456951
Rheumatoid factor positive 50.62 14.20 42 239540 652 31457110
Hypothyroidism 50.60 14.20 37 239545 17910 31439852
Ataxia 50.59 14.20 17 239565 12846 31444916
Alopecia 50.54 14.20 298 239284 20397 31437365
Blood pressure systolic increased 50.06 14.20 44 239538 19426 31438336
Transplant rejection 49.94 14.20 7 239575 9701 31448061
Fibromyalgia 49.67 14.20 82 239500 2744 31455018
Chronic obstructive pulmonary disease 49.50 14.20 175 239407 44991 31412771
Irritability 49.49 14.20 60 239522 22829 31434933
Bronchospasm 49.44 14.20 8 239574 9964 31447798
Feeling hot 49.25 14.20 248 239334 15985 31441777
Terminal state 49.19 14.20 95 239487 3603 31454159
Bacteraemia 48.89 14.20 37 239545 17597 31440165
Electrocardiogram abnormal 48.72 14.20 3 239579 8033 31449729
Mania 48.69 14.20 6 239576 9171 31448591
Pulmonary thrombosis 48.64 14.20 138 239444 6747 31451015
Shock haemorrhagic 48.62 14.20 9 239573 10168 31447594
Hepatotoxicity 48.25 14.20 44 239538 19082 31438680
Venous injury 48.09 14.20 29 239553 261 31457501
Balance disorder 48.05 14.20 135 239447 37287 31420475
Mitral valve incompetence 47.92 14.20 23 239559 14010 31443752
Back disorder 47.89 14.20 127 239455 5966 31451796
Haemodialysis 47.74 14.20 9 239573 10036 31447726
Pustular psoriasis 47.69 14.20 60 239522 1557 31456205
Right ventricular failure 47.60 14.20 4 239578 8278 31449484
Lyme disease 47.15 14.20 46 239536 891 31456871
Rotator cuff syndrome 47.13 14.20 115 239467 5130 31452632
Acute myeloid leukaemia 47.05 14.20 43 239539 18629 31439133
Atrioventricular block complete 46.94 14.20 5 239577 8560 31449202
Rash papular 46.94 14.20 155 239427 8237 31449525
Haematochezia 46.92 14.20 153 239429 40311 31417451
Lymphopenia 46.67 14.20 25 239557 14304 31443458
Lipase increased 46.38 14.20 6 239576 8837 31448925
Neck surgery 46.37 14.20 31 239551 339 31457423
Tricuspid valve incompetence 46.29 14.20 6 239576 8823 31448939
Chills 46.24 14.20 349 239233 73801 31383961
Insurance issue 46.14 14.20 52 239530 1198 31456564
Nightmare 46.09 14.20 17 239565 12120 31445642
Prothrombin time prolonged 45.88 14.20 7 239575 9105 31448657
Clostridium difficile infection 45.71 14.20 38 239544 17241 31440521
Product quality issue 45.70 14.20 33 239549 16078 31441684
Tooth loss 45.39 14.20 92 239490 3616 31454146
Thrombotic microangiopathy 45.26 14.20 8 239574 9343 31448419
Urosepsis 45.21 14.20 16 239566 11704 31446058
Myopathy 45.09 14.20 13 239569 10839 31446923
Rash pruritic 44.58 14.20 322 239260 23616 31434146
Activated partial thromboplastin time prolonged 44.57 14.20 5 239577 8220 31449542
Oesophagitis 44.51 14.20 19 239563 12397 31445365
Cytopenia 44.28 14.20 14 239568 10996 31446766
Body temperature decreased 43.84 14.20 17 239565 11753 31446009
Duodenal ulcer 43.82 14.20 10 239572 9754 31448008
Scab 43.81 14.20 97 239485 4058 31453704
Nephrolithiasis 43.79 14.20 355 239227 26984 31430778
Gastric disorder 43.73 14.20 188 239394 11340 31446422
Drug specific antibody present 43.62 14.20 78 239504 2787 31454975
Oliguria 43.62 14.20 4 239578 7713 31450049
Cyst 43.57 14.20 97 239485 4073 31453689
Burning sensation 43.40 14.20 245 239337 16502 31441260
Myelodysplastic syndrome 43.20 14.20 49 239533 19202 31438560
Full blood count abnormal 43.18 14.20 36 239546 16311 31441451
Left ventricular dysfunction 43.18 14.20 9 239573 9348 31448414
Obstructive airways disorder 42.88 14.20 21 239561 12643 31445119
Purpura 42.82 14.20 10 239572 9600 31448162
Ankle deformity 42.69 14.20 25 239557 212 31457550
Hypoalbuminaemia 42.64 14.20 15 239567 11013 31446749
Aspiration 42.62 14.20 14 239568 10732 31447030
Post procedural infection 42.61 14.20 101 239481 4422 31453340
Prescribed underdose 42.51 14.20 6 239576 8272 31449490
Hepatitis 42.47 14.20 63 239519 22003 31435759
Substance abuse 42.43 14.20 3 239579 7155 31450607
Transient ischaemic attack 42.23 14.20 73 239509 23983 31433779
Tooth abscess 42.09 14.20 110 239472 5122 31452640
Blood calcium decreased 42.06 14.20 10 239572 9484 31448278
Dental implantation 42.05 14.20 17 239565 55 31457707
Acne 41.91 14.20 170 239412 9990 31447772
Cytology abnormal 41.87 14.20 30 239552 370 31457392
Proteinuria 41.77 14.20 39 239543 16724 31441038
Anhedonia 41.68 14.20 4 239578 7438 31450324
Hyperuricaemia 41.65 14.20 4 239578 7434 31450328
Oedema peripheral 41.25 14.20 583 238999 109256 31348506
Spondylitis 41.25 14.20 47 239535 1096 31456666
Injection site nodule 41.23 14.20 54 239528 1460 31456302
Hyperthyroidism 41.02 14.20 11 239571 9620 31448142
Elbow operation 40.82 14.20 20 239562 113 31457649
Cardiac failure chronic 40.71 14.20 4 239578 7299 31450463
Gait inability 40.68 14.20 266 239316 18878 31438884
Nail pitting 40.64 14.20 25 239557 234 31457528
Device failure 40.59 14.20 64 239518 2059 31455703
Device related infection 40.52 14.20 38 239544 16261 31441501
Paranasal sinus discomfort 40.49 14.20 38 239544 700 31457062
Respiratory rate increased 40.44 14.20 10 239572 9235 31448527
Failure to thrive 40.35 14.20 6 239576 7956 31449806
Eye operation 40.35 14.20 28 239554 327 31457435
Gastritis 39.97 14.20 57 239525 20235 31437527
Incorrect disposal of product 39.95 14.20 27 239555 301 31457461
Emotional distress 39.95 14.20 30 239552 14326 31443436
Paranoia 39.72 14.20 15 239567 10540 31447222
Subarachnoid haemorrhage 39.66 14.20 14 239568 10257 31447505
Hepatitis cholestatic 39.61 14.20 4 239578 7142 31450620
Klebsiella infection 39.27 14.20 6 239576 7797 31449965
Asthma 39.16 14.20 177 239405 42434 31415328
Toxic skin eruption 39.10 14.20 14 239568 10166 31447596
Toe operation 39.01 14.20 14 239568 29 31457733
Product prescribing error 38.87 14.20 55 239527 19587 31438175
Angina unstable 38.77 14.20 18 239564 11177 31446585
Macule 38.68 14.20 45 239537 1074 31456688
Bronchopulmonary aspergillosis 38.58 14.20 28 239554 13606 31444156
Rash erythematous 38.53 14.20 298 239284 22329 31435433
Hernia repair 38.45 14.20 46 239536 1132 31456630
Exposure during pregnancy 38.20 14.20 9 239573 8589 31449173
Schizophrenia 38.15 14.20 17 239565 10813 31446949
Arthrodesis 38.13 14.20 30 239552 430 31457332
Hypercalcaemia 38.01 14.20 30 239552 13970 31443792
Hyperthermia 38.01 14.20 14 239568 9990 31447772
Pulmonary sarcoidosis 37.52 14.20 32 239550 517 31457245
Hypovolaemic shock 37.48 14.20 3 239579 6459 31451303
Product use issue 37.37 14.20 263 239319 56496 31401266
Withdrawal syndrome 37.35 14.20 21 239561 11696 31446066
Pulmonary haemorrhage 37.31 14.20 13 239569 9602 31448160
Ankle operation 37.23 14.20 23 239559 217 31457545
Hip surgery 37.08 14.20 41 239541 924 31456838
Polyuria 36.93 14.20 7 239575 7776 31449986
Gastric haemorrhage 36.79 14.20 14 239568 9791 31447971
Rash macular 36.64 14.20 177 239405 11218 31446544
Viral upper respiratory tract infection 36.57 14.20 69 239513 2571 31455191
Hepatic cytolysis 36.56 14.20 18 239564 10805 31446957
Transaminases increased 36.55 14.20 81 239501 24260 31433502
Progressive multifocal leukoencephalopathy 36.54 14.20 12 239570 9201 31448561
Intestinal ischaemia 36.43 14.20 5 239577 7040 31450722
Second primary malignancy 36.34 14.20 5 239577 7027 31450735
Sacroiliitis 36.31 14.20 48 239534 1310 31456452
Bundle branch block right 36.28 14.20 5 239577 7019 31450743
Parkinsonism 35.95 14.20 7 239575 7629 31450133
Pericardial effusion 35.86 14.20 72 239510 22351 31435411
Arteriosclerosis coronary artery 35.85 14.20 20 239562 11188 31446574
Dental operation 35.63 14.20 27 239555 365 31457397
Arthropod sting 35.54 14.20 26 239556 332 31457430
Osteosclerosis 35.18 14.20 45 239537 1188 31456574
End stage renal disease 35.03 14.20 9 239573 8100 31449662
Muscle spasms 34.81 14.20 717 238865 67601 31390161
Nail psoriasis 34.70 14.20 15 239567 60 31457702
Haemorrhagic stroke 34.70 14.20 3 239579 6067 31451695
Basal cell carcinoma 34.70 14.20 246 239336 17933 31439829
Discomfort 34.59 14.20 227 239355 16129 31441633
Gallbladder operation 34.54 14.20 29 239553 458 31457304
Acute generalised exanthematous pustulosis 34.49 14.20 3 239579 6037 31451725
Blood pressure diastolic decreased 34.41 14.20 9 239573 8004 31449758
Skin injury 34.34 14.20 54 239528 1733 31456029
Injection site coldness 34.34 14.20 11 239571 13 31457749
Intestinal sepsis 34.30 14.20 31 239551 543 31457219
Pseudomonas infection 34.15 14.20 22 239560 11379 31446383
Depression 34.10 14.20 482 239100 90333 31367429
Polyarthritis 33.80 14.20 89 239493 4163 31453599
Neoplasm malignant 33.74 14.20 252 239330 18679 31439083
Candida infection 33.71 14.20 44 239538 16214 31441548
Hiccups 33.63 14.20 14 239568 9273 31448489
Apnoea 33.59 14.20 4 239578 6278 31451484
Disturbance in attention 33.47 14.20 75 239507 22375 31435387
Coordination abnormal 33.41 14.20 7 239575 7244 31450518
Injection site hypersensitivity 33.12 14.20 23 239559 269 31457493
Injection site hypoaesthesia 33.07 14.20 15 239567 69 31457693
Toothache 32.77 14.20 108 239474 5733 31452029
Guttate psoriasis 32.65 14.20 19 239563 159 31457603
Meniscus operation 32.58 14.20 10 239572 9 31457753
Nail bed disorder 32.58 14.20 10 239572 9 31457753
Blood loss anaemia 32.53 14.20 9 239573 7710 31450052
Neck mass 32.50 14.20 49 239533 1515 31456247
Drug dependence 32.40 14.20 77 239505 22502 31435260
Lethargy 32.31 14.20 166 239416 38475 31419287
Hemiparesis 32.24 14.20 39 239543 14855 31442907
Intestinal polyp 32.14 14.20 38 239544 923 31456839
Left ventricular hypertrophy 31.94 14.20 8 239574 7324 31450438
Hepatic enzyme abnormal 31.84 14.20 62 239520 2366 31455396
Liver injury 31.76 14.20 33 239549 13459 31444303
Eye disorder 31.75 14.20 138 239444 8364 31449398
Nocturia 31.74 14.20 15 239567 9220 31448542
Gastroenteritis viral 31.66 14.20 112 239470 6165 31451597
Weight increased 31.58 14.20 439 239143 82508 31375254
Hepatic enzyme increased 31.42 14.20 412 239170 35496 31422266
Hypogammaglobulinaemia 31.36 14.20 6 239576 6621 31451141
Staphylococcal infection 31.36 14.20 362 239220 30270 31427492
Atrial septal defect 31.28 14.20 7 239575 6920 31450842
Hydronephrosis 30.98 14.20 16 239566 9345 31448417
Ear congestion 30.87 14.20 27 239555 452 31457310
Accident at work 30.77 14.20 32 239550 671 31457091
Psychomotor hyperactivity 30.63 14.20 14 239568 8773 31448989
Peritonitis bacterial 30.62 14.20 4 239578 5848 31451914
Gastroenteritis 30.58 14.20 33 239549 13229 31444533
Myocardial infarction 30.37 14.20 640 238942 112814 31344948
Heart rate irregular 30.32 14.20 38 239544 14251 31443511
Ependymoma malignant 30.28 14.20 10 239572 14 31457748
Transfusion 30.22 14.20 10 239572 7630 31450132
Ventricular extrasystoles 30.10 14.20 24 239558 11118 31446644
Rheumatoid lung 30.08 14.20 33 239549 737 31457025
Cataract operation 30.03 14.20 41 239541 1155 31456607
Arthritis infective 29.89 14.20 68 239514 2897 31454865
Artificial crown procedure 29.49 14.20 10 239572 16 31457746
Appendicitis 29.37 14.20 26 239556 11439 31446323
C-reactive protein increased 29.36 14.20 524 239058 48126 31409636
Peritonitis 29.26 14.20 44 239538 15283 31442479
Gastritis erosive 29.16 14.20 4 239578 5635 31452127
Oral herpes 29.06 14.20 92 239490 4781 31452981
Cholangitis 28.98 14.20 12 239570 7974 31449788
Hyperlipidaemia 28.98 14.20 34 239548 13126 31444636
Head injury 28.83 14.20 51 239531 16607 31441155
Petechiae 28.71 14.20 15 239567 8705 31449057
Interstitial lung disease 28.66 14.20 311 239271 61092 31396670
Lung neoplasm malignant 28.33 14.20 215 239367 16015 31441747
Pulmonary fibrosis 28.14 14.20 219 239363 16441 31441321
Supraventricular tachycardia 28.09 14.20 22 239560 10285 31447477
Viral infection 28.03 14.20 208 239374 15385 31442377
Limb crushing injury 28.03 14.20 14 239568 83 31457679
Rocky mountain spotted fever 27.93 14.20 9 239573 11 31457751
Osteolysis 27.82 14.20 57 239525 2258 31455504
Low birth weight baby 27.78 14.20 9 239573 6961 31450801
Trigger finger 27.71 14.20 31 239551 708 31457054
Arthritis bacterial 27.68 14.20 87 239495 4503 31453259
Asphyxia 27.66 14.20 5 239577 5746 31452016
Cardiac failure acute 27.57 14.20 20 239562 9721 31448041
Aplasia pure red cell 27.57 14.20 5 239577 5732 31452030
Carpal tunnel syndrome 27.55 14.20 84 239498 4277 31453485
Ingrown hair 27.47 14.20 17 239565 161 31457601
Anal incontinence 27.40 14.20 10 239572 7176 31450586
Chest discomfort 27.27 14.20 240 239342 49129 31408633
Lupus-like syndrome 27.16 14.20 59 239523 2436 31455326
Hypotonia 27.07 14.20 10 239572 7123 31450639
Haemophagocytic lymphohistiocytosis 27.00 14.20 29 239553 11649 31446113
Colitis 26.98 14.20 148 239434 33739 31424023
Wrong product administered 26.97 14.20 3 239579 4965 31452797
Drug resistance 26.96 14.20 89 239493 23364 31434398
Prostatic operation 26.86 14.20 22 239560 335 31457427
Rubber sensitivity 26.81 14.20 16 239566 141 31457621
Adverse drug reaction 26.78 14.20 300 239282 24901 31432861
Obsessive-compulsive disorder 26.76 14.20 3 239579 4934 31452828
Device occlusion 26.73 14.20 6 239576 5919 31451843
Breast feeding 26.71 14.20 8 239574 6 31457756
Body temperature increased 26.67 14.20 46 239536 15127 31442635
Axial spondyloarthritis 26.60 14.20 22 239560 340 31457422
Chromaturia 26.54 14.20 37 239545 13261 31444501
Cardiomyopathy 26.49 14.20 47 239535 15286 31442476
Lung infiltration 26.42 14.20 32 239550 12181 31445581
Limb deformity 26.27 14.20 26 239556 513 31457249
Hepatitis acute 26.15 14.20 9 239573 6700 31451062
Glycosylated haemoglobin increased 26.14 14.20 24 239558 10376 31447386
Pemphigoid 26.11 14.20 15 239567 8256 31449506
Dialysis 26.03 14.20 25 239557 10578 31447184
Diabetes mellitus inadequate control 25.89 14.20 35 239547 12706 31445056
Ventricular hypokinesia 25.85 14.20 3 239579 4803 31452959
Benign prostatic hyperplasia 25.72 14.20 37 239545 13088 31444674
Dermatitis contact 25.65 14.20 66 239516 3044 31454718
Gynaecomastia 25.64 14.20 19 239563 9135 31448627
Blood glucose decreased 25.60 14.20 34 239548 12437 31445325
Carpal tunnel decompression 25.58 14.20 17 239565 184 31457578
Iron deficiency anaemia 25.48 14.20 20 239562 9339 31448423
Rales 25.43 14.20 17 239565 8622 31449140
Increased upper airway secretion 25.26 14.20 45 239537 1603 31456159
Colitis ulcerative 25.17 14.20 65 239517 18464 31439298
Acute pulmonary oedema 25.09 14.20 11 239571 7065 31450697
Hepatitis B virus test positive 25.06 14.20 20 239562 293 31457469
Intervertebral disc operation 25.05 14.20 18 239564 223 31457539
Erectile dysfunction 24.97 14.20 69 239513 19166 31438596
Medical device implantation 24.97 14.20 27 239555 593 31457169
Premature baby 24.83 14.20 63 239519 18003 31439759
Eosinophil count increased 24.78 14.20 14 239568 7777 31449985
Dysuria 24.74 14.20 97 239485 24197 31433565
Squamous cell carcinoma 24.72 14.20 152 239430 10559 31447203
Aplastic anaemia 24.64 14.20 20 239562 9183 31448579
Arteriosclerosis 24.60 14.20 27 239555 10740 31447022
Paraesthesia 24.59 14.20 576 239006 55495 31402267
Meningitis viral 24.42 14.20 31 239551 812 31456950
Onychomadesis 24.32 14.20 25 239557 517 31457245
Product complaint 24.12 14.20 6 239576 5518 31452244
Ageusia 24.09 14.20 21 239561 9310 31448452
Bundle branch block left 24.08 14.20 6 239576 5512 31452250
Myositis 24.07 14.20 29 239553 11065 31446697
Blood magnesium decreased 23.91 14.20 7 239575 5779 31451983
Dermatitis atopic 23.88 14.20 4 239578 4858 31452904
Toxic encephalopathy 23.80 14.20 4 239578 4846 31452916
Colitis ischaemic 23.80 14.20 8 239574 6044 31451718
Lung consolidation 23.79 14.20 6 239576 5467 31452295
Decubitus ulcer 23.75 14.20 15 239567 7841 31449921
Amylase increased 23.71 14.20 6 239576 5456 31452306
Injection site hyperaesthesia 23.51 14.20 7 239575 5 31457757
Gastric ulcer haemorrhage 23.49 14.20 5 239577 5118 31452644
Ileus paralytic 23.37 14.20 6 239576 5402 31452360
Tendon sheath incision 23.36 14.20 6 239576 0 31457762
Amyotrophic lateral sclerosis 23.30 14.20 33 239549 963 31456799
Embolism 23.12 14.20 13 239569 7240 31450522
Lower gastrointestinal haemorrhage 23.11 14.20 19 239563 8670 31449092
Memory impairment 23.11 14.20 411 239171 37719 31420043
Liver function test increased 23.08 14.20 170 239412 12544 31445218
Cerebral haematoma 23.01 14.20 3 239579 4392 31453370
Retinal haemorrhage 22.99 14.20 4 239578 4726 31453036
Walking aid user 22.96 14.20 43 239539 1593 31456169
Ecchymosis 22.91 14.20 10 239572 6440 31451322
Haemolysis 22.90 14.20 13 239569 7203 31450559
Pulmonary embolism 22.90 14.20 457 239125 81189 31376573
Pain of skin 22.89 14.20 76 239506 4050 31453712
Limb injury 22.86 14.20 142 239440 9899 31447863
Ischaemic cardiomyopathy 22.83 14.20 8 239574 5889 31451873
Muscle swelling 22.81 14.20 20 239562 336 31457426
Ischaemia 22.79 14.20 3 239579 4360 31453402
Mouth haemorrhage 22.76 14.20 5 239577 5007 31452755
Cachexia 22.73 14.20 11 239571 6668 31451094
Systemic lupus erythematosus 22.68 14.20 62 239520 2966 31454796
International normalised ratio decreased 22.65 14.20 3 239579 4340 31453422
Brain injury 22.54 14.20 8 239574 5842 31451920
Ventricular hypertrophy 22.47 14.20 3 239579 4313 31453449
Ligament operation 22.45 14.20 7 239575 7 31457755
Hypertransaminasaemia 22.38 14.20 3 239579 4301 31453461
Hyperaesthesia teeth 22.20 14.20 23 239559 480 31457282
Dementia 22.16 14.20 37 239545 12323 31445439
Euphoric mood 22.16 14.20 5 239577 4915 31452847
Ligament rupture 22.08 14.20 31 239551 897 31456865
Atrioventricular block 22.06 14.20 14 239568 7301 31450461
Exposure to communicable disease 21.99 14.20 14 239568 140 31457622
Dental caries 21.91 14.20 77 239505 4224 31453538
Haemolytic anaemia 21.90 14.20 25 239557 9771 31447991
Post procedural haemorrhage 21.86 14.20 16 239566 7742 31450020
Pulmonary alveolar haemorrhage 21.75 14.20 12 239570 6754 31451008
Infected bite 21.69 14.20 20 239562 360 31457402
Complication associated with device 21.66 14.20 7 239575 5422 31452340
Stent placement 21.62 14.20 82 239500 4669 31453093
Pulseless electrical activity 21.52 14.20 12 239570 6715 31451047
Nail infection 21.44 14.20 16 239566 211 31457551
Faeces discoloured 21.42 14.20 45 239537 13741 31444021
Incontinence 21.39 14.20 7 239575 5379 31452383
Haemorrhoids 21.35 14.20 38 239544 12344 31445418
Blood phosphorus increased 21.33 14.20 4 239578 4478 31453284
Pulse absent 21.33 14.20 7 239575 5370 31452392
Prostatic specific antigen increased 21.20 14.20 44 239538 13494 31444268
Cutaneous sarcoidosis 21.18 14.20 14 239568 150 31457612
Pneumocystis jirovecii pneumonia 21.16 14.20 69 239513 18182 31439580
Duodenal ulcer haemorrhage 21.02 14.20 5 239577 4741 31453021
Tonsil cancer 20.95 14.20 32 239550 1001 31456761
Immune thrombocytopenia 20.90 14.20 20 239562 8478 31449284
Cardiovascular disorder 20.90 14.20 24 239558 9354 31448408
Pathological fracture 20.86 14.20 3 239579 4079 31453683
Hospice care 20.86 14.20 8 239574 5568 31452194
Metastases to bone 20.85 14.20 31 239551 10817 31446945
Bradyphrenia 20.81 14.20 4 239578 4400 31453362
Protein total decreased 20.62 14.20 5 239577 4679 31453083
Partial seizures 20.56 14.20 4 239578 4362 31453400
Coronary artery stenosis 20.53 14.20 22 239560 8848 31448914
False positive tuberculosis test 20.32 14.20 6 239576 4 31457758
Product administration error 20.32 14.20 54 239528 15193 31442569
Frustration tolerance decreased 20.30 14.20 51 239531 2317 31455445
Herpes ophthalmic 20.28 14.20 22 239560 485 31457277
Nephropathy 20.26 14.20 8 239574 5471 31452291
Sunburn 20.26 14.20 42 239540 1678 31456084
Device dislocation 20.08 14.20 7 239575 5169 31452593
Blood culture positive 20.06 14.20 5 239577 4593 31453169
Tooth impacted 20.06 14.20 10 239572 59 31457703
Systemic lupus erythematosus rash 20.06 14.20 10 239572 59 31457703
Red cell distribution width increased 19.99 14.20 8 239574 5426 31452336
Cerebral ischaemia 19.97 14.20 10 239572 5945 31451817
Lower respiratory tract infection 19.92 14.20 312 239270 27925 31429837
Secretion discharge 19.88 14.20 82 239500 4855 31452907
Blood triglycerides increased 19.77 14.20 45 239537 13352 31444410
Flatulence 19.71 14.20 75 239507 18873 31438889
Injection site anaesthesia 19.66 14.20 7 239575 14 31457748
Soft tissue swelling 19.64 14.20 19 239563 364 31457398
Papule 19.61 14.20 63 239519 3299 31454463
Cartilage injury 19.58 14.20 22 239560 505 31457257
Injection site laceration 19.54 14.20 8 239574 27 31457735
Neonatal respiratory distress syndrome 19.52 14.20 3 239579 3882 31453880
Bunion operation 19.46 14.20 5 239577 0 31457762
Tuberculin test 19.46 14.20 5 239577 0 31457762
Hangnail 19.46 14.20 5 239577 0 31457762
Propionibacterium infection 19.41 14.20 16 239566 246 31457516
Device dispensing error 19.41 14.20 9 239573 44 31457718
Gastric ulcer 19.37 14.20 52 239530 14582 31443180
Limb mass 19.20 14.20 25 239557 672 31457090
Obesity 19.19 14.20 34 239548 11066 31446696
Wrist surgery 19.16 14.20 13 239569 146 31457616
Respiratory syncytial virus infection 19.16 14.20 3 239579 3828 31453934
Oral candidiasis 19.09 14.20 34 239548 11043 31446719
Blood albumin decreased 18.96 14.20 41 239541 12390 31445372
Intervertebral disc disorder 18.95 14.20 42 239540 1758 31456004
Cholecystitis 18.92 14.20 28 239554 9789 31447973
Tendon operation 18.90 14.20 8 239574 30 31457732
Ejection fraction decreased 18.80 14.20 68 239514 17366 31440396
Brain herniation 18.79 14.20 3 239579 3774 31453988
Road traffic accident 18.78 14.20 198 239384 16183 31441579
Gastrointestinal disorder 18.76 14.20 331 239251 30329 31427433
Enterococcal infection 18.75 14.20 23 239559 8708 31449054
Foetal heart rate decreased 18.64 14.20 9 239573 49 31457713
Hypertensive crisis 18.49 14.20 21 239561 8226 31449536
Cervical vertebral fracture 18.45 14.20 42 239540 1790 31455972
Aspergillus infection 18.45 14.20 37 239545 11491 31446271
Cholelithiasis 18.44 14.20 80 239502 19399 31438363
Occupational exposure to product 18.44 14.20 18 239564 349 31457413
Fine motor skill dysfunction 18.44 14.20 40 239542 1650 31456112
Hypertriglyceridaemia 18.43 14.20 19 239563 7779 31449983
Rheumatoid factor 18.43 14.20 10 239572 72 31457690
Pneumatosis intestinalis 18.35 14.20 3 239579 3708 31454054
Generalised oedema 18.33 14.20 37 239545 11464 31446298
General symptom 18.31 14.20 27 239555 818 31456944
Weight fluctuation 18.24 14.20 6 239576 4596 31453166
Cyst removal 18.13 14.20 8 239574 34 31457728
Skin irritation 18.12 14.20 77 239505 4620 31453142
Muscle spasticity 18.10 14.20 10 239572 5625 31452137
Seronegative arthritis 18.08 14.20 29 239553 947 31456815
Injury 18.02 14.20 82 239500 19627 31438135
Metabolic disorder 17.97 14.20 4 239578 3970 31453792
Ligament disorder 17.88 14.20 11 239571 103 31457659
Dysgeusia 17.86 14.20 104 239478 23362 31434400
Immunosuppression 17.83 14.20 87 239495 5536 31452226
Peripheral sensory neuropathy 17.83 14.20 13 239569 6302 31451460
Cytomegalovirus infection reactivation 17.68 14.20 4 239578 3925 31453837
Peripheral ischaemia 17.62 14.20 9 239573 5291 31452471
Device defective 17.60 14.20 22 239560 567 31457195
Swollen tongue 17.56 14.20 45 239537 12817 31444945
Ankle fracture 17.56 14.20 64 239518 3575 31454187
Stomatitis 17.55 14.20 406 239176 39032 31418730
Injection site pustule 17.55 14.20 6 239576 10 31457752
Animal bite 17.54 14.20 21 239561 517 31457245
Mononucleosis syndrome 17.53 14.20 9 239573 57 31457705
Maternal drugs affecting foetus 17.51 14.20 4 239578 3899 31453863
Bladder transitional cell carcinoma recurrent 17.45 14.20 12 239570 138 31457624
Jaundice cholestatic 17.42 14.20 6 239576 4464 31453298
Head discomfort 17.40 14.20 65 239517 3674 31454088
Pneumonia bacterial 17.39 14.20 32 239550 10264 31447498
Spinal disorder 17.30 14.20 67 239515 3853 31453909
Eating disorder 17.27 14.20 19 239563 7550 31450212
Spinal laminectomy 17.25 14.20 15 239567 249 31457513
Malignant melanoma stage I 17.25 14.20 10 239572 83 31457679
Wisdom teeth removal 17.25 14.20 10 239572 83 31457679
Sinus node dysfunction 17.23 14.20 4 239578 3856 31453906
Product distribution issue 17.19 14.20 19 239563 428 31457334
Thyroid cancer 17.19 14.20 38 239544 1588 31456174
Blood thyroid stimulating hormone increased 17.17 14.20 3 239579 3534 31454228
Ankle arthroplasty 17.14 14.20 5 239577 3 31457759
Joint surgery 17.14 14.20 5 239577 3 31457759
Lymphadenopathy 17.07 14.20 285 239297 25836 31431926
Renal tubular disorder 17.05 14.20 6 239576 4404 31453358
Ammonia increased 17.04 14.20 5 239577 4122 31453640
Cholecystitis acute 16.99 14.20 11 239571 5676 31452086
Food intolerance 16.99 14.20 33 239549 1257 31456505
Nocardiosis 16.97 14.20 3 239579 3504 31454258
Acute graft versus host disease 16.94 14.20 13 239569 6140 31451622
Pulmonary function test decreased 16.89 14.20 6 239576 4379 31453383
Carotid artery stenosis 16.87 14.20 7 239575 4645 31453117
Erythrodermic psoriasis 16.84 14.20 26 239556 821 31456941
Body temperature abnormal 16.81 14.20 21 239561 541 31457221
HLA-B*27 positive 16.80 14.20 7 239575 25 31457737
Carbuncle 16.80 14.20 7 239575 25 31457737
Muscle haemorrhage 16.79 14.20 3 239579 3477 31454285
Taste disorder 16.79 14.20 11 239571 5639 31452123
Affect lability 16.69 14.20 3 239579 3462 31454300
Muscular weakness 16.69 14.20 372 239210 65076 31392686
Mental impairment 16.66 14.20 29 239553 9503 31448259
Injection site oedema 16.66 14.20 13 239569 184 31457578
Polychondritis 16.63 14.20 14 239568 222 31457540
Sudden cardiac death 16.58 14.20 3 239579 3446 31454316
Systemic infection 16.58 14.20 3 239579 3446 31454316
Erythema multiforme 16.57 14.20 22 239560 8049 31449713
Fibrin D dimer increased 16.56 14.20 3 239579 3443 31454319
Infected cyst 16.47 14.20 20 239562 500 31457262
BK virus infection 16.43 14.20 9 239573 5086 31452676
Manufacturing product shipping issue 16.39 14.20 7 239575 27 31457735
Hyperhidrosis 16.35 14.20 386 239196 67007 31390755
Nail discolouration 16.34 14.20 26 239556 843 31456919
Hemiplegia 16.32 14.20 16 239566 6706 31451056
Pneumothorax 16.28 14.20 69 239513 16841 31440921
Serum ferritin increased 16.25 14.20 12 239570 5780 31451982
Tongue disorder 16.18 14.20 78 239504 4939 31452823
Intestinal perforation 16.09 14.20 24 239558 8365 31449397
Injection site discharge 16.04 14.20 10 239572 96 31457666
Gingival discolouration 16.04 14.20 5 239577 5 31457757
Ear neoplasm 16.01 14.20 9 239573 70 31457692
Polyneuropathy 15.96 14.20 48 239534 12974 31444788
Intervertebral disc injury 15.95 14.20 6 239576 15 31457747
Frequent bowel movements 15.92 14.20 33 239549 10126 31447636
Odynophagia 15.84 14.20 9 239573 4984 31452778
Spinal fusion acquired 15.82 14.20 7 239575 30 31457732
Gastrointestinal perforation 15.75 14.20 4 239578 3628 31454134
Necrosis 15.71 14.20 10 239572 5206 31452556
Whipple's disease 15.68 14.20 6 239576 16 31457746
Thrombotic thrombocytopenic purpura 15.68 14.20 3 239579 3310 31454452
Skin cancer 15.64 14.20 123 239459 9262 31448500
Nasal discharge discolouration 15.64 14.20 14 239568 242 31457520
Intracranial pressure increased 15.64 14.20 4 239578 3611 31454151
Breath sounds abnormal 15.64 14.20 13 239569 5899 31451863
Secondary amyloidosis 15.60 14.20 9 239573 74 31457688
Cast application 15.57 14.20 4 239578 0 31457762
Anticipatory anxiety 15.57 14.20 4 239578 0 31457762
Dactylitis 15.55 14.20 25 239557 818 31456944
Intraocular pressure increased 15.55 14.20 10 239572 5177 31452585
Metabolic encephalopathy 15.54 14.20 5 239577 3884 31453878
Granuloma 15.54 14.20 53 239529 2864 31454898
Stress 15.53 14.20 270 239312 24671 31433091
Pyelonephritis 15.51 14.20 12 239570 5644 31452118
Graft versus host disease 15.49 14.20 35 239547 10412 31447350
Hospitalisation 15.44 14.20 274 239308 49533 31408229
Protein urine present 15.42 14.20 9 239573 4911 31452851
Drug screen positive 15.31 14.20 5 239577 3847 31453915
Tendonitis 15.29 14.20 114 239468 8444 31449318
Neutrophilia 15.25 14.20 5 239577 3838 31453924
Anger 15.24 14.20 39 239543 11114 31446648
Non-cardiac chest pain 15.23 14.20 6 239576 4109 31453653
Penile squamous cell carcinoma 15.21 14.20 9 239573 78 31457684
Septic arthritis staphylococcal 15.19 14.20 19 239563 490 31457272
Tachyarrhythmia 15.19 14.20 3 239579 3236 31454526
Plantar fasciitis 15.14 14.20 36 239546 1579 31456183
Abdominal operation 15.11 14.20 9 239573 79 31457683
Upper-airway cough syndrome 15.09 14.20 55 239527 3072 31454690
Scar 15.06 14.20 82 239500 5448 31452314
Syringe issue 15.05 14.20 9 239573 4847 31452915
Poor venous access 15.02 14.20 6 239576 4074 31453688
Dermatitis bullous 15.01 14.20 15 239567 6230 31451532
Impaired quality of life 15.00 14.20 4 239578 3512 31454250
Intentional dose omission 15.00 14.20 51 239531 2751 31455011
Abnormal dreams 14.98 14.20 19 239563 7089 31450673
Portal vein thrombosis 14.94 14.20 4 239578 3503 31454259
Systemic inflammatory response syndrome 14.91 14.20 15 239567 6210 31451552
Lower limb fracture 14.90 14.20 63 239519 3772 31453990
Bacterial sepsis 14.90 14.20 9 239573 4819 31452943
Dermatitis acneiform 14.86 14.20 13 239569 5754 31452008
Nasal cavity cancer 14.86 14.20 12 239570 179 31457583
Mixed connective tissue disease 14.81 14.20 7 239575 36 31457726
Proctalgia 14.80 14.20 8 239574 4554 31453208
Tumour necrosis factor receptor-associated periodic syndrome 14.75 14.20 5 239577 8 31457754
Alcohol poisoning 14.73 14.20 3 239579 3168 31454594
Papillary cystadenoma lymphomatosum 14.66 14.20 7 239575 37 31457725
Abdominal pain lower 14.65 14.20 30 239552 9246 31448516
Dental care 14.61 14.20 13 239569 223 31457539
Nail bed bleeding 14.56 14.20 13 239569 224 31457538
Productive cough 14.53 14.20 344 239238 33196 31424566
X-ray abnormal 14.52 14.20 18 239564 460 31457302
Major depression 14.48 14.20 7 239575 4246 31453516
C-reactive protein decreased 14.44 14.20 38 239544 1777 31455985
Spondyloarthropathy 14.42 14.20 20 239562 572 31457190
Blood pressure diastolic abnormal 14.41 14.20 6 239576 3973 31453789
Precancerous skin lesion 14.40 14.20 20 239562 573 31457189
Metastases to lung 14.38 14.20 26 239556 8396 31449366
Miller Fisher syndrome 14.37 14.20 8 239574 61 31457701
Respiratory disorder 14.34 14.20 78 239504 17822 31439940
Hypertonia 14.34 14.20 6 239576 3962 31453800
Muscle tightness 14.31 14.20 70 239512 4459 31453303
International normalised ratio abnormal 14.28 14.20 3 239579 3099 31454663
Skin swelling 14.25 14.20 29 239553 1143 31456619
Eosinophilic pneumonia 14.25 14.20 3 239579 3094 31454668
Skin lesion 14.24 14.20 217 239365 19310 31438452
Drooling 14.23 14.20 3 239579 3092 31454670
Ventricular septal defect 14.22 14.20 5 239577 3672 31454090
Arthroscopy 14.22 14.20 9 239573 89 31457673

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Injection site pain 48905.29 13.85 26149 935479 91470 69875346
Injection site erythema 47036.50 13.85 21860 939768 51064 69915752
Injection site pruritus 25804.64 13.85 11937 949691 27273 69939543
Injection site swelling 25542.25 13.85 12210 949418 30947 69935869
Injection site reaction 18294.56 13.85 10232 951396 39620 69927196
Injection site bruising 16337.82 13.85 8666 952962 29366 69937450
Injection site warmth 13405.59 13.85 5535 956093 8290 69958526
Psoriasis 12772.58 13.85 10613 951015 87820 69878996
Rheumatoid arthritis 12374.30 13.85 17367 944261 274438 69692378
Arthralgia 10212.84 13.85 21589 940039 481801 69485015
Drug ineffective 8625.25 13.85 30040 931588 909712 69057104
Wrong technique in product usage process 8362.36 13.85 7144 954484 61554 69905262
Injection site rash 7957.85 13.85 4059 957569 12351 69954465
Injection site haemorrhage 7736.70 13.85 4631 956997 20896 69945920
Injection site urticaria 6180.82 13.85 3062 958566 8576 69958240
Joint swelling 5637.53 13.85 11308 950320 241903 69724913
Pain in extremity 5476.33 13.85 13044 948584 315038 69651778
Acute kidney injury 4914.92 13.85 410 961218 474214 69492602
Nasopharyngitis 4491.52 13.85 9540 952088 212666 69754150
Pain 4445.61 13.85 18545 943083 610271 69356545
Injection site discolouration 4277.65 13.85 2036 959592 5056 69961760
Product storage error 4037.49 13.85 2495 959133 12046 69954770
Toxicity to various agents 4024.87 13.85 305 961323 381867 69584949
Product dose omission issue 3914.04 13.85 8913 952715 208555 69758261
Drug interaction 3912.74 13.85 342 961286 381099 69585717
Therapeutic product effect decreased 3906.36 13.85 6975 954653 136043 69830773
Sinusitis 3848.77 13.85 7630 953998 161565 69805251
Injection site induration 3808.19 13.85 2045 959583 7123 69959693
Therapeutic product effect incomplete 3800.38 13.85 6247 955381 113635 69853181
Device issue 3671.62 13.85 2855 958773 21170 69945646
Hypotension 3560.85 13.85 603 961025 403778 69563038
Accidental exposure to product 3452.47 13.85 2938 958690 25113 69941703
Musculoskeletal stiffness 3204.69 13.85 6534 955094 141226 69825590
Anaemia 3009.25 13.85 871 960757 402552 69564264
Completed suicide 2938.95 13.85 25 961603 227110 69739706
Injection site mass 2853.24 13.85 2203 959425 16140 69950676
Death 2793.88 13.85 1736 959892 508325 69458491
Mobility decreased 2720.89 13.85 4953 956675 98046 69868770
Febrile neutropenia 2446.42 13.85 70 961558 204248 69762568
Swelling 2394.27 13.85 6775 954853 181764 69785052
Neutropenia 2236.22 13.85 395 961233 256761 69710055
Therapeutic response decreased 2130.72 13.85 3249 958379 55204 69911612
Thrombocytopenia 2079.58 13.85 367 961261 238743 69728073
Dyspnoea 2063.26 13.85 4630 956998 765430 69201386
Psoriatic arthropathy 2057.03 13.85 3380 958248 61391 69905425
Musculoskeletal pain 2037.32 13.85 4062 957566 86265 69880551
Joint stiffness 2020.42 13.85 2439 959189 32737 69934079
Treatment failure 1975.03 13.85 5327 956301 138815 69828001
Hyponatraemia 1919.29 13.85 54 961574 160033 69806783
Arthritis 1862.23 13.85 4108 957520 93872 69872944
Underdose 1854.32 13.85 2138 959490 27245 69939571
Drug abuse 1790.41 13.85 43 961585 147213 69819603
Injection site discomfort 1749.44 13.85 973 960655 3696 69963120
Arthropathy 1635.59 13.85 5110 956518 144947 69821869
Constipation 1613.83 13.85 701 960927 251737 69715079
Cardiac arrest 1605.25 13.85 155 961473 159679 69807137
Malignant neoplasm progression 1590.84 13.85 10 961618 121729 69845087
Dehydration 1541.89 13.85 569 961059 225573 69741243
Diarrhoea 1505.03 13.85 5515 956113 777826 69188990
Bradycardia 1482.76 13.85 45 961583 124570 69842246
Peripheral swelling 1476.21 13.85 6736 954892 229827 69736989
Abdominal pain 1455.90 13.85 1495 960133 340632 69626184
Injection site haematoma 1436.50 13.85 820 960808 3314 69963502
Drug intolerance 1419.77 13.85 6442 955186 219245 69747571
Vomiting 1409.04 13.85 3791 957837 589320 69377496
Respiratory failure 1398.71 13.85 291 961337 168444 69798372
Synovitis 1350.50 13.85 4338 957290 124890 69841926
Contraindicated product administered 1345.83 13.85 4451 957177 130161 69836655
Injection site extravasation 1343.82 13.85 1043 960585 7703 69959113
Disease progression 1338.89 13.85 251 961377 156421 69810395
Tachycardia 1337.96 13.85 262 961366 158284 69808532
Hyperkalaemia 1336.33 13.85 21 961607 106570 69860246
Pancytopenia 1313.04 13.85 232 961396 150875 69815941
Seizure 1301.45 13.85 397 961231 177565 69789251
Haemoglobin decreased 1268.30 13.85 597 961031 204562 69762254
Hypokalaemia 1261.53 13.85 149 961479 131039 69835777
Respiratory tract congestion 1260.24 13.85 1370 960258 16283 69950533
Gastrointestinal haemorrhage 1259.10 13.85 182 961446 137226 69829590
Intentional overdose 1219.05 13.85 23 961605 98412 69868404
Rhabdomyolysis 1195.68 13.85 20 961608 95740 69871076
Overdose 1189.39 13.85 408 961220 169337 69797479
Skin plaque 1181.57 13.85 1014 960614 8769 69958047
Platelet count decreased 1159.23 13.85 482 961146 177740 69789076
Knee arthroplasty 1134.79 13.85 1824 959804 32477 69934339
Cardio-respiratory arrest 1134.21 13.85 55 961573 100622 69866194
Renal failure 1132.46 13.85 574 961054 188496 69778320
Confusional state 1131.72 13.85 1313 960315 283085 69683731
Sepsis 1111.29 13.85 1007 960621 243538 69723278
Atrial fibrillation 1099.14 13.85 563 961065 183785 69783031
Syncope 1094.22 13.85 438 961190 165271 69801545
Electrocardiogram QT prolonged 1075.66 13.85 10 961618 83507 69883309
Musculoskeletal disorder 1031.33 13.85 1313 960315 18658 69948158
Hypoxia 1023.35 13.85 60 961568 93284 69873532
Hypoglycaemia 1021.45 13.85 65 961563 94299 69872517
Decreased appetite 1014.56 13.85 1603 960025 303177 69663639
Oxygen saturation decreased 1008.70 13.85 180 961448 116249 69850567
Surgery 1006.14 13.85 1605 960023 28384 69938432
Depressed level of consciousness 987.34 13.85 47 961581 87384 69879432
Cardiac failure 964.82 13.85 369 961259 143172 69823644
Somnolence 956.81 13.85 907 960721 214699 69752117
Oropharyngeal pain 956.34 13.85 3178 958450 93132 69873684
International normalised ratio increased 950.02 13.85 32 961596 80694 69886122
Product use in unapproved indication 946.51 13.85 851 960777 206627 69760189
Agitation 912.82 13.85 100 961528 93275 69873541
Blood creatinine increased 910.24 13.85 399 961229 142602 69824214
Injection site macule 898.83 13.85 319 961309 210 69966606
Multiple organ dysfunction syndrome 891.13 13.85 191 961437 108324 69858492
Influenza 884.91 13.85 3465 958163 110235 69856581
Cardiac failure congestive 874.83 13.85 370 961258 135087 69831729
Metabolic acidosis 873.03 13.85 30 961598 74316 69892500
Injection site recall reaction 870.83 13.85 288 961340 99 69966717
Coma 864.11 13.85 112 961516 91732 69875084
Suicide attempt 862.85 13.85 54 961574 79456 69887360
Lactic acidosis 831.71 13.85 9 961619 65015 69901801
Neutrophil count decreased 830.86 13.85 84 961544 83472 69883344
Ankylosing spondylitis 829.84 13.85 903 960725 10743 69956073
Pulmonary embolism 824.15 13.85 550 961078 155317 69811499
Therapy interrupted 812.31 13.85 1313 960315 23489 69943327
Bronchitis 808.64 13.85 3442 958186 113801 69853015
Finger deformity 800.67 13.85 665 960963 5471 69961345
Incorrect dose administered by device 784.25 13.85 575 961053 3854 69962962
Nodule 764.30 13.85 1136 960492 18833 69947983
Blood pressure decreased 759.79 13.85 157 961471 91358 69875458
Pleural effusion 747.78 13.85 436 961192 132428 69834388
Renal impairment 734.29 13.85 528 961100 143409 69823407
Infection 732.44 13.85 5131 956497 205654 69761162
Injection site vesicles 732.19 13.85 461 961167 2312 69964504
Plasma cell myeloma 721.60 13.85 76 961552 73125 69893691
Injury associated with device 709.47 13.85 466 961162 2546 69964270
C-reactive protein abnormal 703.67 13.85 1592 960036 36987 69929829
Unevaluable event 701.91 13.85 1914 959714 50149 69916667
Asthenia 681.36 13.85 3541 958087 454125 69512691
White blood cell count decreased 677.86 13.85 784 960844 169357 69797459
Hallucination 671.20 13.85 113 961515 76147 69890669
Mental status changes 669.58 13.85 48 961580 63053 69903763
Red blood cell sedimentation rate abnormal 668.05 13.85 1048 960580 18255 69948561
Deep vein thrombosis 666.27 13.85 336 961292 110706 69856110
General physical health deterioration 659.39 13.85 1382 960246 234649 69732167
Weight decreased 657.77 13.85 2091 959537 308397 69658419
Drug reaction with eosinophilia and systemic symptoms 655.58 13.85 31 961597 57982 69908834
Acute myocardial infarction 654.96 13.85 102 961526 72785 69894031
Drug hypersensitivity 653.76 13.85 5918 955710 256541 69710275
Hyperglycaemia 653.56 13.85 61 961567 64611 69902205
Therapy non-responder 650.17 13.85 2407 959221 74508 69892308
Pulmonary oedema 647.22 13.85 159 961469 82119 69884697
Pneumonia aspiration 628.81 13.85 59 961569 62230 69904586
Fear of injection 627.72 13.85 601 961027 6071 69960745
Ascites 624.35 13.85 87 961541 67460 69899356
Injection site irritation 622.01 13.85 451 961177 2964 69963852
Headache 620.78 13.85 11179 950449 569226 69397590
Hypersensitivity 620.01 13.85 5274 956354 224538 69742278
Melaena 618.34 13.85 36 961592 56319 69910497
Blood creatine phosphokinase increased 615.87 13.85 59 961569 61204 69905612
Blood bilirubin increased 612.04 13.85 54 961574 59847 69906969
Loss of consciousness 605.87 13.85 731 960897 154985 69811831
Septic shock 604.33 13.85 388 961240 111870 69854946
Pyrexia 603.90 13.85 5295 956333 601657 69365159
Paranasal sinus hypersecretion 600.26 13.85 438 961190 2911 69963905
Nausea 598.46 13.85 8057 953571 844031 69122785
Foot deformity 594.41 13.85 1032 960596 19623 69947193
Inflammation 593.03 13.85 2374 959254 76291 69890525
Blood pressure increased 584.63 13.85 1037 960591 187480 69779336
Encephalopathy 580.45 13.85 75 961553 61586 69905230
Unresponsive to stimuli 579.63 13.85 30 961598 51901 69914915
Respiratory arrest 578.14 13.85 39 961589 53894 69912922
Orthostatic hypotension 577.19 13.85 30 961598 51713 69915103
Sedation 566.39 13.85 14 961614 46717 69920099
Injection site inflammation 565.47 13.85 427 961201 3011 69963805
Neoplasm progression 558.15 13.85 11 961617 45217 69921599
Coronary artery disease 556.47 13.85 91 961537 62645 69904171
Mucosal inflammation 553.78 13.85 121 961507 67729 69899087
Dysarthria 544.71 13.85 94 961534 62219 69904597
Alopecia 544.66 13.85 4573 957055 193917 69772899
Ear infection 544.48 13.85 1194 960434 27142 69939674
Rhinorrhoea 541.76 13.85 2054 959574 64317 69902499
Multiple sclerosis relapse 541.07 13.85 8 961620 43009 69923807
Alanine aminotransferase increased 535.79 13.85 729 960899 146751 69820065
Delirium 535.22 13.85 172 961456 74442 69892374
Tremor 534 13.85 801 960827 154823 69811993
Respiratory distress 530.36 13.85 60 961568 54590 69912226
Blood alkaline phosphatase increased 530.13 13.85 80 961548 58441 69908375
Hand deformity 527.40 13.85 2448 959180 84034 69882782
Condition aggravated 526.20 13.85 8428 953200 419207 69547609
Serotonin syndrome 524.78 13.85 9 961619 42105 69924711
Grip strength decreased 518.58 13.85 834 960794 14851 69951965
Pneumonia 516.95 13.85 5380 956248 590852 69375964
Drug dose omission by device 513.57 13.85 439 961189 3773 69963043
Fall 501.87 13.85 3742 957886 440354 69526462
Neck pain 497.10 13.85 2005 959623 64652 69902164
Leukopenia 495.35 13.85 429 961199 106131 69860685
Hypomagnesaemia 494.86 13.85 12 961616 40752 69926064
Heart rate increased 491.42 13.85 429 961199 105719 69861097
Dyspnoea exertional 490.82 13.85 224 961404 78206 69888610
Bone marrow failure 490.53 13.85 48 961580 48962 69917854
Haematuria 490.07 13.85 128 961500 63445 69903371
Hepatic failure 484.24 13.85 96 961532 57529 69909287
Upper respiratory tract infection 484.14 13.85 2245 959383 77029 69889787
Urinary retention 482.22 13.85 69 961559 52451 69914365
Gamma-glutamyltransferase increased 481.08 13.85 60 961568 50625 69916191
Chest pain 481.05 13.85 1767 959861 249493 69717323
Aspartate aminotransferase increased 480.33 13.85 609 961019 126369 69840447
Pharyngitis streptococcal 479.64 13.85 616 961012 8832 69957984
Herpes zoster 476.51 13.85 2353 959275 82882 69883934
Haematemesis 474.98 13.85 53 961575 48744 69918072
Aggression 470.60 13.85 53 961575 48393 69918423
Cholestasis 468.50 13.85 51 961577 47821 69918995
Acute respiratory failure 462.44 13.85 84 961544 53581 69913235
Blood urea increased 459.38 13.85 45 961583 45864 69920952
Disorientation 455.41 13.85 112 961516 57811 69909005
Cerebral haemorrhage 454.16 13.85 89 961539 53775 69913041
Lymphocyte count decreased 453.75 13.85 36 961592 43503 69923313
Dizziness 451.79 13.85 4070 957558 460071 69506745
Cerebrovascular accident 451.25 13.85 782 960846 142688 69824128
Drug level increased 449.50 13.85 9 961619 36460 69930356
Hip arthroplasty 444.91 13.85 1096 960532 26944 69939872
Gait disturbance 443.85 13.85 4141 957487 180965 69785851
Contusion 441.50 13.85 3112 958516 124924 69841892
Jaundice 441.48 13.85 74 961554 50034 69916782
Red blood cell sedimentation rate increased 438.92 13.85 1336 960292 37306 69929510
Hypervolaemia 433.67 13.85 26 961602 39680 69927136
Chronic kidney disease 432.19 13.85 144 961484 60913 69905903
Dysphagia 431.11 13.85 537 961091 112297 69854519
Agranulocytosis 429.43 13.85 30 961598 40268 69926548
Suicidal ideation 428.95 13.85 203 961425 69393 69897423
Shock 428.17 13.85 31 961597 40394 69926422
Heart rate decreased 425.63 13.85 154 961474 61861 69904955
Hypertension 422.88 13.85 2321 959307 293712 69673104
Sinus congestion 418.80 13.85 804 960824 16569 69950247
Angioedema 417.18 13.85 190 961438 66420 69900396
Toxic epidermal necrolysis 417.06 13.85 31 961597 39526 69927290
Loss of personal independence in daily activities 415.01 13.85 2258 959370 82652 69884164
Feeling abnormal 405.76 13.85 3308 958320 139011 69827805
Cardiogenic shock 405.11 13.85 21 961607 36286 69930530
Neuropathy peripheral 404.24 13.85 686 960942 126210 69840606
Impaired healing 402.84 13.85 2035 959593 72339 69894477
Hepatocellular injury 399.63 13.85 71 961557 46020 69920796
Bone erosion 399.19 13.85 729 960899 14444 69952372
Psychotic disorder 396.20 13.85 30 961598 37671 69929145
Sinus headache 395.47 13.85 391 961237 4122 69962694
Upper gastrointestinal haemorrhage 393.34 13.85 30 961598 37447 69929369
Altered state of consciousness 393.27 13.85 42 961586 39980 69926836
Eosinophilia 391.90 13.85 44 961584 40275 69926541
Myocardial infarction 390.28 13.85 1118 960510 170527 69796289
Joint range of motion decreased 386.47 13.85 992 960636 25034 69941782
Ventricular tachycardia 385.57 13.85 28 961600 36395 69930421
Pancreatitis acute 384.93 13.85 73 961555 45151 69921665
Haematochezia 380.58 13.85 262 961366 72819 69893997
Rectal haemorrhage 380.35 13.85 209 961419 65622 69901194
Pulmonary arterial hypertension 379.67 13.85 15 961613 32840 69933976
Blood pressure systolic increased 378.28 13.85 151 961477 57108 69909708
Pulmonary hypertension 375.69 13.85 85 961543 46451 69920365
Generalised tonic-clonic seizure 374.95 13.85 58 961570 41603 69925213
Oedema 371.11 13.85 517 961111 103064 69863752
Adverse event 369.73 13.85 1489 960139 47972 69918844
Hypocalcaemia 368.09 13.85 79 961549 44780 69922036
Circulatory collapse 367.82 13.85 30 961598 35444 69931372
Arrhythmia 364.50 13.85 152 961476 55991 69910825
Knee operation 364.22 13.85 394 961234 4653 69962163
Haemorrhage 364.00 13.85 359 961269 83456 69883360
Blood glucose increased 361.03 13.85 522 961106 102460 69864356
Drug withdrawal syndrome 358.58 13.85 21 961607 32694 69934122
Intentional self-injury 357.31 13.85 17 961611 31633 69935183
Osteonecrosis of jaw 353.67 13.85 64 961564 40938 69925878
Flushing 353.37 13.85 355 961273 81817 69884999
Injection site hypersensitivity 352.64 13.85 247 961381 1525 69965291
Back pain 351.84 13.85 5394 956234 265758 69701058
Rash maculo-papular 351.17 13.85 123 961505 50422 69916394
Accidental overdose 349.90 13.85 35 961593 35086 69931730
Haematocrit decreased 349.82 13.85 169 961459 57089 69909727
Anxiety 348.13 13.85 1668 959960 218662 69748154
Sinus tachycardia 347.99 13.85 30 961598 33883 69932933
Blood lactate dehydrogenase increased 347.38 13.85 36 961592 35091 69931725
Cognitive disorder 347.15 13.85 197 961431 60759 69906057
Leukocytosis 341.98 13.85 62 961566 39606 69927210
Cerebral infarction 340.38 13.85 82 961546 42927 69923889
Injection site nodule 338.90 13.85 315 961313 3055 69963761
Diabetic ketoacidosis 337.11 13.85 23 961605 31489 69935327
Transplant dysfunction 335.96 13.85 441 961187 6468 69960348
Neuroleptic malignant syndrome 335.36 13.85 3 961625 26004 69940812
Osteoarthritis 334.59 13.85 1930 959698 72217 69894599
Cough 333.99 13.85 6231 955397 319146 69647670
Stevens-Johnson syndrome 332.39 13.85 46 961582 35861 69930955
Foot operation 331.12 13.85 368 961260 4489 69962327
Rheumatoid factor positive 327.28 13.85 1413 960215 46987 69919829
Disability 326.88 13.85 665 960963 14318 69952498
Myoclonus 326.86 13.85 6 961622 26349 69940467
Joint destruction 326.79 13.85 359 961269 4319 69962497
Epilepsy 325.05 13.85 65 961563 38719 69928097
Blood pressure fluctuation 324.37 13.85 199 961429 58813 69908003
Therapy cessation 323.16 13.85 1099 960529 32577 69934239
Acute respiratory distress syndrome 321.92 13.85 81 961547 41173 69925643
Malaise 321.67 13.85 7910 953718 425022 69541794
Oedema peripheral 319.18 13.85 1800 959828 226291 69740525
Exposure during pregnancy 314.04 13.85 438 961190 87279 69879537
Tachypnoea 312.01 13.85 19 961609 28619 69938197
Abnormal behaviour 310.82 13.85 49 961579 34660 69932156
Therapeutic product effect delayed 308.37 13.85 274 961354 2493 69964323
Haematoma 306.49 13.85 136 961492 48282 69918534
Sneezing 306.25 13.85 697 960931 16254 69950562
Increased tendency to bruise 305.67 13.85 504 961124 9171 69957645
Ejection fraction decreased 305.56 13.85 31 961597 30731 69936085
Labelled drug-drug interaction medication error 305.55 13.85 4 961624 24123 69942693
Aphasia 304.34 13.85 103 961525 43146 69923670
Acute hepatic failure 302.57 13.85 18 961610 27654 69939162
Status epilepticus 302.48 13.85 6 961622 24520 69942296
Posterior reversible encephalopathy syndrome 300.83 13.85 6 961622 24396 69942420
Adverse reaction 299.80 13.85 468 961160 8114 69958702
Inappropriate antidiuretic hormone secretion 298.65 13.85 3 961625 23273 69943543
Subdural haematoma 297.69 13.85 27 961601 29271 69937545
Hallucination, visual 295.51 13.85 28 961600 29309 69937507
Arthropod bite 294.15 13.85 426 961202 6889 69959927
Adverse drug reaction 294.06 13.85 1467 960161 51877 69914939
Spinal operation 290.98 13.85 415 961213 6613 69960203
Injection site injury 290.45 13.85 156 961472 543 69966273
Sinus disorder 289.14 13.85 730 960898 18229 69948587
Myelosuppression 287.75 13.85 35 961593 30110 69936706
Hepatic function abnormal 287.54 13.85 298 961330 67698 69899118
Restlessness 285.06 13.85 107 961521 42021 69924795
Nasal congestion 285.03 13.85 1692 959936 63980 69902836
Device expulsion 284.82 13.85 3 961625 22243 69944573
Tubulointerstitial nephritis 284.48 13.85 52 961576 33024 69933792
Haemorrhage intracranial 283.99 13.85 12 961616 24765 69942051
Ventricular fibrillation 283.68 13.85 22 961606 27089 69939727
Tooth infection 283.20 13.85 664 960964 15799 69951017
Palpitations 281.65 13.85 682 960946 110071 69856745
Systemic lupus erythematosus 280.91 13.85 2351 959277 99551 69867265
Juvenile idiopathic arthritis 280.15 13.85 369 961259 5431 69961385
Neutropenic sepsis 278.17 13.85 14 961614 24816 69942000
Coagulopathy 278.07 13.85 56 961572 33193 69933623
Pericardial effusion 277.87 13.85 109 961519 41667 69925149
Renal tubular necrosis 276.83 13.85 8 961620 23163 69943653
Electrolyte imbalance 274.96 13.85 24 961604 26837 69939979
Pancreatitis 274.90 13.85 266 961362 62402 69904414
Haemoptysis 273.87 13.85 180 961448 51272 69915544
Angina pectoris 273.18 13.85 158 961470 48225 69918591
Localised infection 272.84 13.85 1029 960599 32129 69934687
Fluid retention 272.34 13.85 274 961354 63111 69903705
Ischaemic stroke 270.42 13.85 46 961582 30774 69936042
Poisoning 269.58 13.85 8 961620 22614 69944202
Blood calcium decreased 269.28 13.85 36 961592 28810 69938006
Limb discomfort 269.03 13.85 951 960677 28754 69938062
Sinus bradycardia 268.91 13.85 12 961616 23611 69943205
Joint lock 267.32 13.85 261 961367 2706 69964110
Sleep disorder due to general medical condition, insomnia type 267.28 13.85 1076 960552 34656 69932160
Acne 267.13 13.85 846 960782 24143 69942673
Iritis 266.92 13.85 275 961353 3057 69963759
Small intestinal obstruction 266.68 13.85 17 961611 24638 69942178
Abdominal distension 266.59 13.85 644 960984 104025 69862791
Clostridium difficile colitis 266.40 13.85 38 961590 28958 69937858
Pneumonitis 264.54 13.85 211 961417 54386 69912430
Cytomegalovirus infection 264.01 13.85 104 961524 39654 69927162
Hepatic encephalopathy 262.92 13.85 8 961620 22110 69944706
Chondrolysis 261.78 13.85 117 961511 236 69966580
Intentional product misuse 260.58 13.85 1911 959717 77684 69889132
Fibromyalgia 259.24 13.85 1310 960318 46564 69920252
Dyskinesia 259.00 13.85 116 961512 40958 69925858
Hyperbilirubinaemia 255.15 13.85 12 961616 22556 69944260
Colitis 254.01 13.85 294 961334 63520 69903296
Device malfunction 251.56 13.85 696 960932 18388 69948428
Extra dose administered 248.88 13.85 393 961235 6884 69959932
Shoulder arthroplasty 248.82 13.85 251 961377 2716 69964100
Lethargy 247.78 13.85 398 961230 74852 69891964
Disseminated intravascular coagulation 247.10 13.85 74 961554 33524 69933292
Blood pressure diastolic decreased 245.91 13.85 30 961598 25750 69941066
Right ventricular failure 245.03 13.85 14 961614 22260 69944556
Extrapyramidal disorder 241.38 13.85 9 961619 20741 69946075
Rheumatoid nodule 241.20 13.85 591 961037 14476 69952340
Gastrooesophageal reflux disease 240.06 13.85 548 961080 90291 69876525
Hemiparesis 237.54 13.85 66 961562 31403 69935413
Urinary incontinence 236.85 13.85 108 961520 37734 69929082
Transaminases increased 235.06 13.85 176 961452 46842 69919974
Corrective lens user 234.72 13.85 98 961530 153 69966663
Mycobacterium tuberculosis complex test positive 234.47 13.85 218 961410 2115 69964701
Presyncope 234.08 13.85 107 961521 37331 69929485
Medication error 233.29 13.85 256 961372 56656 69910160
Hypothermia 232.67 13.85 11 961617 20583 69946233
Withdrawal syndrome 232.66 13.85 31 961597 24873 69941943
Cyanosis 231.50 13.85 23 961605 23183 69943633
Chondropathy 230.70 13.85 220 961408 2210 69964606
Anuria 230.44 13.85 8 961620 19645 69947171
COVID-19 230.04 13.85 703 960925 105054 69861762
Bacteraemia 229.74 13.85 57 961571 29252 69937564
Ileus 229.25 13.85 29 961599 24208 69942608
Balance disorder 227.57 13.85 557 961071 89571 69877245
Spinal fusion surgery 227.52 13.85 276 961352 3721 69963095
Tumour lysis syndrome 227.30 13.85 16 961612 21344 69945472
Brain oedema 226.48 13.85 26 961602 23392 69943424
Shoulder operation 223.89 13.85 216 961412 2204 69964612
Decreased immune responsiveness 222.27 13.85 303 961325 4618 69962198
Chest discomfort 222.15 13.85 899 960729 123482 69843334
Joint noise 222.02 13.85 253 961375 3178 69963638
Dystonia 221.11 13.85 11 961617 19695 69947121
Lymphopenia 220.78 13.85 50 961578 27309 69939507
Obstructive airways disorder 220.43 13.85 43 961585 26070 69940746
Hypophagia 219.13 13.85 147 961481 41423 69925393
Blood potassium decreased 216.99 13.85 155 961473 42266 69924550
Gastritis 216.45 13.85 172 961456 44419 69922397
Drug-induced liver injury 216.43 13.85 265 961363 55848 69910968
Acidosis 215.67 13.85 7 961621 18256 69948560
Joint injury 215.17 13.85 828 960800 26104 69940712
Cardiomegaly 214.55 13.85 37 961591 24508 69942308
Joint arthroplasty 211.82 13.85 215 961413 2345 69964471
Myelodysplastic syndrome 211.20 13.85 70 961558 29715 69937101
Face oedema 210.66 13.85 45 961583 25594 69941222
Skin haemorrhage 210.52 13.85 442 961186 9738 69957078
Intestinal obstruction 210.50 13.85 133 961495 38692 69928124
Ovarian cyst 210.39 13.85 482 961146 11290 69955526
Hepatic enzyme increased 209.92 13.85 3140 958488 153850 69812966
Myalgia 209.07 13.85 1374 960254 166518 69800298
Impaired work ability 208.56 13.85 589 961039 15751 69951065
Joint effusion 207.52 13.85 568 961060 14909 69951907
Intentional product use issue 206.70 13.85 881 960747 119261 69847555
Ear pain 206.34 13.85 831 960797 26768 69940048
Product prescribing error 206.33 13.85 137 961491 38815 69928001
Acute myeloid leukaemia 205.33 13.85 81 961547 30859 69935957
Emotional distress 204.93 13.85 125 961503 37063 69929753
Limb operation 204.69 13.85 230 961398 2842 69963974
Abdominal discomfort 204.02 13.85 4064 957564 210594 69756222
Shock haemorrhagic 203.50 13.85 10 961618 18096 69948720
Rubber sensitivity 203.36 13.85 166 961462 1329 69965487
Tuberculin test positive 201.03 13.85 234 961394 3012 69963804
Rash pruritic 200.84 13.85 1503 960125 61488 69905328
Anti-cyclic citrullinated peptide antibody positive 200.21 13.85 1632 959996 68553 69898263
Blood sodium decreased 199.47 13.85 85 961543 30913 69935903
Transient ischaemic attack 199.21 13.85 197 961431 45747 69921069
Injection site papule 197.09 13.85 130 961498 716 69966100
COVID-19 pneumonia 196.75 13.85 31 961597 21938 69944878
Ataxia 196.47 13.85 38 961590 23179 69943637
Device dislocation 194.39 13.85 35 961593 22472 69944344
Asthma 193.25 13.85 910 960718 119883 69846933
Skin discolouration 192.79 13.85 1008 960620 36317 69930499
Muscle rigidity 192.72 13.85 16 961612 18634 69948182
Myocardial ischaemia 191.76 13.85 46 961582 24154 69942662
Treatment noncompliance 191.45 13.85 209 961419 46365 69920451
Device failure 191.15 13.85 309 961319 5526 69961290
Joint warmth 190.62 13.85 162 961466 1380 69965436
Ill-defined disorder 190.56 13.85 1334 960294 53407 69913409
Acute coronary syndrome 189.97 13.85 24 961604 20055 69946761
Left ventricular dysfunction 189.50 13.85 14 961614 17943 69948873
Wheezing 189.48 13.85 648 960980 93522 69873294
Chronic obstructive pulmonary disease 188.89 13.85 489 961139 77152 69889664
White blood cell count increased 187.66 13.85 415 961213 69158 69897658
Antibiotic therapy 187.37 13.85 122 961506 655 69966161
Troponin increased 187.29 13.85 9 961619 16605 69950211
Atrial flutter 185.90 13.85 27 961601 20300 69946516
Speech disorder 185.61 13.85 248 961380 50332 69916484
Nephropathy toxic 185.60 13.85 18 961610 18496 69948320
Hypoalbuminaemia 185.50 13.85 21 961607 19101 69947715
Mania 185.28 13.85 12 961616 17162 69949654
Respiratory rate increased 184.94 13.85 24 961604 19648 69947168
Myocarditis 183.93 13.85 20 961608 18773 69948043
Circumstance or information capable of leading to medication error 183.69 13.85 235 961393 3355 69963461
Malnutrition 183.47 13.85 28 961600 20289 69946527
Thrombotic microangiopathy 182.55 13.85 16 961612 17832 69948984
Pallor 181.94 13.85 172 961456 40802 69926014
Hypothyroidism 181.88 13.85 211 961417 45544 69921272
Drug ineffective for unapproved indication 181.65 13.85 153 961475 38385 69928431
Sudden death 181.40 13.85 33 961595 21031 69945785
Haemodialysis 179.17 13.85 15 961613 17351 69949465
Device related infection 179.01 13.85 107 961521 32078 69934738
Acute generalised exanthematous pustulosis 178.00 13.85 7 961621 15390 69951426
Toxic skin eruption 177.10 13.85 30 961598 20132 69946684
Oliguria 176.92 13.85 6 961622 15045 69951771
Hepatic cytolysis 176.66 13.85 25 961603 19167 69947649
Product quality issue 176.55 13.85 97 961531 30464 69936352
Body temperature decreased 176.08 13.85 84 961544 28588 69938228
Red blood cell count decreased 175.39 13.85 272 961356 51889 69914927
Mydriasis 175.12 13.85 11 961617 16142 69950674
Haemodynamic instability 174.86 13.85 9 961619 15649 69951167
Neutrophil count increased 174.79 13.85 72 961556 26723 69940093
Pemphigus 174.55 13.85 1808 959820 81228 69885588
Rash 174.08 13.85 8525 953103 502037 69464779
Anhedonia 173.22 13.85 4 961624 14209 69952607
Mitral valve incompetence 172.45 13.85 73 961555 26655 69940161
Gastroenteritis 171.88 13.85 105 961523 31108 69935708
Tricuspid valve incompetence 171.76 13.85 20 961608 17797 69949019
Miosis 171.73 13.85 4 961624 14097 69952719
Delusion 171.73 13.85 27 961601 19138 69947678
Supraventricular tachycardia 171.65 13.85 30 961598 19680 69947136
Anaphylactic shock 171.11 13.85 115 961513 32375 69934441
Pruritus 170.76 13.85 6002 955626 339558 69627258
Anaphylactic reaction 169.07 13.85 490 961138 74484 69892332
Renal injury 168.55 13.85 13 961615 16081 69950735
Hallucination, auditory 168.42 13.85 24 961604 18304 69948512
Transfusion 167.73 13.85 27 961601 18809 69948007
Furuncle 167.60 13.85 323 961305 6675 69960141
Parkinsonism 167.45 13.85 10 961618 15315 69951501
Myopathy 167.27 13.85 26 961602 18586 69948230
Full blood count decreased 166.48 13.85 58 961570 23860 69942956
Glomerular filtration rate decreased 165.36 13.85 39 961589 20717 69946099
Cholelithiasis 164.84 13.85 241 961387 47099 69919717
Bronchospasm 164.37 13.85 52 961576 22740 69944076
Prothrombin time prolonged 164.27 13.85 15 961613 16175 69950641
Blood pressure diastolic abnormal 163.86 13.85 12 961616 15492 69951324
Cytopenia 163.18 13.85 21 961607 17302 69949514
Atrioventricular block complete 162.39 13.85 11 961617 15152 69951664
Scratch 162.03 13.85 324 961304 6886 69959930
Bronchopulmonary aspergillosis 160.48 13.85 43 961585 20959 69945857
Klebsiella infection 160.29 13.85 8 961620 14284 69952532
Joint fluid drainage 159.91 13.85 80 961548 230 69966586
Urine output decreased 158.83 13.85 21 961607 16949 69949867
Cardiac failure acute 158.14 13.85 24 961604 17463 69949353
Walking aid user 157.51 13.85 340 961288 7641 69959175
Breast cancer 157.03 13.85 882 960746 32667 69934149
Stress 156.94 13.85 1509 960119 66457 69900359
Depression 156.71 13.85 1833 959795 197141 69769675
Hypovolaemia 156.57 13.85 17 961611 15976 69950840
Osteonecrosis 156.56 13.85 101 961527 29059 69937757
Atelectasis 155.93 13.85 100 961528 28862 69937954
Skin laceration 155.79 13.85 730 960898 25148 69941668
Epistaxis 155.55 13.85 788 960840 101839 69864977
Angina unstable 155.32 13.85 17 961611 15876 69950940
Drug resistance 155.18 13.85 173 961455 38017 69928799
No adverse event 154.83 13.85 125 961503 32028 69934788
Erythema 154.33 13.85 3668 957960 195895 69770921
Demyelination 154.11 13.85 318 961310 6918 69959898
Exostosis 153.63 13.85 486 961142 13859 69952957
Full blood count abnormal 153.03 13.85 140 961488 33738 69933078
Hyperthermia 152.79 13.85 22 961606 16649 69950167
Hepatitis cholestatic 152.49 13.85 4 961624 12646 69954170
Lipase increased 152.37 13.85 15 961613 15231 69951585
Immune system disorder 152.19 13.85 380 961248 9421 69957395
Aplastic anaemia 151.03 13.85 23 961605 16693 69950123
Oesophagitis 150.81 13.85 59 961569 22593 69944223
Musculoskeletal discomfort 150.53 13.85 558 961070 17274 69949542
Discomfort 150.41 13.85 2133 959495 103303 69863513
Hypernatraemia 150.31 13.85 5 961623 12756 69954060
Aspiration 149.41 13.85 29 961599 17646 69949170
Proteinuria 149.36 13.85 108 961520 29266 69937550
Injection site paraesthesia 147.55 13.85 92 961536 452 69966364
Subarachnoid haemorrhage 147.03 13.85 41 961587 19463 69947353
Disturbance in attention 146.79 13.85 221 961407 42673 69924143
Secretion discharge 146.69 13.85 447 961181 12486 69954330
Blood potassium increased 146.23 13.85 95 961533 27231 69939585
Haematotoxicity 146.21 13.85 10 961618 13664 69953152
Diabetes mellitus inadequate control 145.86 13.85 62 961566 22583 69944233
Blood loss anaemia 144.87 13.85 14 961614 14427 69952389
Paranoia 144.81 13.85 29 961599 17259 69949557
Clostridium difficile infection 142.75 13.85 190 961438 38626 69928190
Heart rate irregular 141.52 13.85 117 961511 29626 69937190
Peritonitis 141.27 13.85 90 961538 26069 69940747
Second primary malignancy 141.15 13.85 9 961619 13042 69953774
Device use error 141.11 13.85 293 961335 6403 69960413
Schizophrenia 140.72 13.85 28 961600 16740 69950076
Cardiomyopathy 140.70 13.85 92 961536 26281 69940535
Metastases to bone 139.81 13.85 64 961564 22312 69944504
Diverticulitis 139.41 13.85 1007 960621 40727 69926089
Blood albumin decreased 138.70 13.85 63 961565 22064 69944752
Drug level decreased 138.66 13.85 8 961620 12616 69954200
Enterocolitis 138.42 13.85 10 961618 13056 69953760
Interstitial lung disease 138.35 13.85 841 960787 103844 69862972
Eye disorder 138.33 13.85 604 961024 20181 69946635
Glossodynia 136.18 13.85 1781 959847 84706 69882110
Cytomegalovirus viraemia 136.16 13.85 5 961623 11680 69955136
Lower gastrointestinal haemorrhage 135.90 13.85 19 961609 14701 69952115
Activated partial thromboplastin time prolonged 135.73 13.85 13 961615 13492 69953324
Urosepsis 135.48 13.85 78 961550 23871 69942945
Pulseless electrical activity 134.74 13.85 12 961616 13203 69953613
Infusion site pain 134.57 13.85 5 961623 11559 69955257
Drug dependence 133.90 13.85 186 961442 37135 69929681
Blood magnesium decreased 132.77 13.85 21 961607 14820 69951996
Feeling hot 132.52 13.85 1120 960508 47550 69919266
Ventricular extrasystoles 132.48 13.85 41 961587 18185 69948631
Back disorder 132.10 13.85 378 961250 10186 69956630
Spinal pain 131.76 13.85 449 961179 13321 69953495
Enterococcal infection 129.63 13.85 21 961607 14561 69952255
Failure to thrive 128.42 13.85 4 961624 10825 69955991
Toothache 128.38 13.85 543 961085 17887 69948929
Hyperthyroidism 127.83 13.85 56 961572 20035 69946781
Duodenal ulcer 127.22 13.85 26 961602 15254 69951562
Haemolytic anaemia 127.17 13.85 35 961593 16759 69950057
Flatulence 126.56 13.85 201 961427 37980 69928836
Blood lactic acid increased 126.12 13.85 6 961622 11167 69955649
Salivary hypersecretion 125.87 13.85 14 961614 12911 69953905
Nightmare 125.57 13.85 72 961556 22084 69944732
Anal incontinence 125.55 13.85 34 961594 16456 69950360
Rales 125.53 13.85 38 961590 17097 69949719
Increased upper airway secretion 124.97 13.85 200 961428 3545 69963271
Respiratory acidosis 124.88 13.85 3 961625 10278 69956538
Faeces discoloured 124.44 13.85 108 961520 26701 69940115
Hepatitis acute 124.36 13.85 20 961608 13942 69952874
Arteriosclerosis coronary artery 124.28 13.85 33 961595 16182 69950634
Gastroenteritis viral 123.90 13.85 598 961030 20857 69945959
Pseudomonas infection 122.35 13.85 52 961576 18942 69947874
Complication associated with device 122.30 13.85 31 961597 15682 69951134
Off label use 121.83 13.85 8556 953072 734504 69232312
Pustular psoriasis 121.78 13.85 223 961405 4427 69962389
Dialysis 121.46 13.85 42 961586 17360 69949456
Hydronephrosis 120.72 13.85 29 961599 15213 69951603
Pathogen resistance 120.60 13.85 18 961610 13261 69953555
Tardive dyskinesia 120.21 13.85 3 961625 9926 69956890
Acute pulmonary oedema 119.94 13.85 19 961609 13393 69953423
Mass 119.36 13.85 482 961146 15544 69951272
Injection site laceration 118.66 13.85 50 961578 81 69966735
Aspergillus infection 118.20 13.85 47 961581 17821 69948995
Colitis ulcerative 117.81 13.85 173 961455 33750 69933066
Erythema multiforme 117.31 13.85 39 961589 16525 69950291
Wound 116.81 13.85 1935 959693 96797 69870019
Granulocytopenia 116.18 13.85 7 961621 10640 69956176
Toxic encephalopathy 116.15 13.85 6 961622 10400 69956416
Bundle branch block right 115.70 13.85 7 961621 10603 69956213
Abdominal pain lower 115.54 13.85 127 961501 28089 69938727
Substance abuse 115.35 13.85 4 961624 9833 69956983
Rash erythematous 113.40 13.85 1136 960492 50582 69916234
Polyuria 113.31 13.85 22 961606 13384 69953432
Metastases to liver 113.29 13.85 110 961518 25768 69941048
Rheumatoid factor increased 113.24 13.85 119 961509 1356 69965460
Wrist surgery 113.20 13.85 90 961538 691 69966125
Hypovolaemic shock 112.80 13.85 9 961619 10828 69955988
Macule 112.64 13.85 157 961471 2446 69964370
Incorrect disposal of product 111.76 13.85 96 961532 831 69965985
Hypoaesthesia 111.66 13.85 2802 958826 150937 69815879
Blood pressure systolic abnormal 111.65 13.85 20 961608 12889 69953927
End stage renal disease 111.14 13.85 11 961617 11122 69955694
Device difficult to use 111.13 13.85 362 961266 10487 69956329
Eosinophil count increased 111.08 13.85 34 961594 15188 69951628
Haemophagocytic lymphohistiocytosis 110.77 13.85 64 961564 19548 69947268
Meniscus injury 109.65 13.85 252 961376 5915 69960901
Fine motor skill dysfunction 109.60 13.85 223 961405 4801 69962015
Pneumothorax 109.56 13.85 113 961515 25733 69941083
Asphyxia 109.31 13.85 8 961620 10334 69956482
Lung infiltration 109.30 13.85 80 961548 21544 69945272
Hyperuricaemia 109.04 13.85 11 961617 10955 69955861
Hypertensive crisis 108.59 13.85 63 961565 19199 69947617
Irritability 108.09 13.85 222 961406 38003 69928813
Faecaloma 107.89 13.85 9 961619 10442 69956374
Immune thrombocytopenia 107.88 13.85 43 961585 16281 69950535
Therapeutic response delayed 107.43 13.85 97 961531 903 69965913
Polyneuropathy 107.24 13.85 80 961548 21335 69945481
Apnoea 107.07 13.85 11 961617 10798 69956018
Rash papular 106.92 13.85 510 961118 17700 69949116
Taste disorder 106.76 13.85 14 961614 11371 69955445
Cholecystitis 105.39 13.85 76 961552 20625 69946191
Cyst 104.86 13.85 395 961233 12324 69954492
Thrombosis 104.82 13.85 596 961032 74809 69892007
Electrocardiogram abnormal 104.78 13.85 34 961594 14630 69952186
Tooth disorder 104.62 13.85 618 961010 23320 69943496
Ankle operation 104.41 13.85 97 961531 940 69965876
Arthrodesis 104.24 13.85 141 961487 2132 69964684
Chromaturia 104.18 13.85 99 961529 23429 69943387
Gait inability 103.33 13.85 1036 960592 46139 69920677
Arteriosclerosis 103.31 13.85 48 961580 16590 69950226
Psychomotor hyperactivity 103.07 13.85 40 961588 15393 69951423
Hypertriglyceridaemia 102.80 13.85 18 961610 11793 69955023
Hyperlipidaemia 102.66 13.85 103 961525 23760 69943056
Colitis ischaemic 102.40 13.85 32 961596 14105 69952711
Throat irritation 102.32 13.85 824 960804 34480 69932336
Kidney infection 102.25 13.85 528 961100 18927 69947889
Viral upper respiratory tract infection 101.38 13.85 300 961328 8242 69958574
Hypoacusis 101.11 13.85 675 960953 26594 69940222
Frequent bowel movements 100.90 13.85 83 961545 21070 69945746
Uveitis 100.79 13.85 434 961194 14411 69952405
Pulmonary haemorrhage 100.75 13.85 30 961598 13643 69953173
Drug level below therapeutic 100.72 13.85 4 961624 8719 69958097
Diastolic dysfunction 100.56 13.85 7 961621 9426 69957390
Upper respiratory tract congestion 100.40 13.85 141 961487 2213 69964603
Cardiac failure chronic 100.31 13.85 11 961617 10258 69956558
Peripheral sensory neuropathy 100.01 13.85 21 961607 12089 69954727
Hepatic necrosis 99.72 13.85 4 961624 8642 69958174
Poor venous access 99.66 13.85 39 961589 14932 69951884
Amylase increased 99.55 13.85 11 961617 10197 69956619
Intestinal ischaemia 99.47 13.85 21 961607 12043 69954773
Pulse absent 99.24 13.85 7 961621 9323 69957493
Laryngitis 99.16 13.85 407 961221 13224 69953592
Atrioventricular block 98.81 13.85 25 961603 12663 69954153
Hip surgery 98.32 13.85 152 961476 2612 69964204
Hepatotoxicity 98.05 13.85 289 961339 43697 69923119
Hemiplegia 97.91 13.85 33 961595 13862 69952954
Ecchymosis 97.63 13.85 36 961592 14296 69952520
Pemphigoid 97.60 13.85 34 961594 13988 69952828
Ventricular hypokinesia 97.50 13.85 3 961625 8209 69958607
Haemorrhagic stroke 97.48 13.85 12 961616 10230 69956586
Haemorrhoids 97.44 13.85 122 961506 25466 69941350
Hypertransaminasaemia 97.22 13.85 6 961622 8937 69957879
Blood triglycerides increased 96.50 13.85 75 961553 19589 69947227
Iridocyclitis 96.42 13.85 167 961461 3168 69963648
Chills 96.16 13.85 1382 960246 143404 69823412
Skin mass 95.38 13.85 269 961359 7187 69959629
Cholecystitis acute 94.64 13.85 23 961605 11971 69954845
Peritonitis bacterial 94.56 13.85 8 961620 9176 69957640
Cataract operation 94.35 13.85 195 961433 4247 69962569
Cholecystitis chronic 94.29 13.85 9 961619 9367 69957449
Hyperhidrosis 94.21 13.85 1237 960391 130349 69836467
Metastases to central nervous system 93.93 13.85 43 961585 14991 69951825
Urticaria 93.48 13.85 2883 958745 160166 69806650
Haemolysis 93.42 13.85 21 961607 11530 69955286
Hepatomegaly 93.34 13.85 61 961567 17431 69949385
Dysgeusia 93.33 13.85 350 961278 49152 69917664
Petechiae 92.98 13.85 74 961554 19098 69947718
Carpal tunnel decompression 92.76 13.85 70 961558 493 69966323
Gallbladder operation 92.70 13.85 119 961509 1705 69965111
Cerebral ischaemia 92.54 13.85 15 961613 10397 69956419
Ankle deformity 92.41 13.85 75 961553 595 69966221
Jaundice cholestatic 91.88 13.85 9 961619 9175 69957641
Vascular device infection 91.66 13.85 4 961624 8026 69958790
Infusion related reaction 90.66 13.85 2013 959615 195521 69771295
Limb deformity 90.53 13.85 166 961462 3299 69963517
Premature delivery 90.46 13.85 93 961535 21211 69945605
Animal bite 90.44 13.85 135 961493 2246 69964570
Left ventricular hypertrophy 90.00 13.85 15 961613 10187 69956629
Neck surgery 89.81 13.85 112 961516 1556 69965260
Metabolic encephalopathy 89.76 13.85 6 961622 8357 69958459
Influenza like illness 89.69 13.85 1313 960315 64018 69902798
Dermatitis atopic 89.65 13.85 9 961619 8998 69957818
Nail disorder 89.50 13.85 328 961300 10096 69956720
Tooth abscess 88.88 13.85 413 961215 14176 69952640
Infusion site erythema 88.58 13.85 3 961625 7532 69959284
Infusion site extravasation 88.19 13.85 5 961623 8003 69958813
Blood pressure systolic decreased 88.08 13.85 13 961615 9658 69957158
Tooth extraction 87.60 13.85 319 961309 9788 69957028
Rheumatoid factor negative 87.00 13.85 91 961537 1031 69965785
Bradyphrenia 86.91 13.85 15 961613 9931 69956885
Ileus paralytic 86.57 13.85 9 961619 8752 69958064
Hypercapnia 86.46 13.85 7 961621 8322 69958494
Intervertebral disc protrusion 86.29 13.85 543 961085 20960 69945856
Bone disorder 85.98 13.85 466 961162 17024 69949792
Stress cardiomyopathy 85.90 13.85 15 961613 9847 69956969
Forced expiratory volume decreased 85.67 13.85 3 961625 7311 69959505
Pneumocystis jirovecii pneumonia 85.65 13.85 174 961454 29908 69936908
Cardiac disorder 85.64 13.85 464 961164 58951 69907865
Systemic inflammatory response syndrome 85.59 13.85 20 961608 10692 69956124
Inappropriate schedule of product administration 85.55 13.85 1985 959643 105570 69861246
Gastric ulcer 85.40 13.85 190 961438 31600 69935216
Purpura 85.15 13.85 71 961557 17904 69948912
Ketoacidosis 85.08 13.85 3 961625 7266 69959550
Azotaemia 84.89 13.85 5 961623 7748 69959068
Partial seizures 84.89 13.85 7 961621 8198 69958618
Ageusia 84.65 13.85 48 961580 14814 69952002
Product complaint 84.54 13.85 30 961598 12201 69954615
Cystitis haemorrhagic 84.46 13.85 9 961619 8584 69958232
Oral surgery 84.38 13.85 85 961543 918 69965898
Rotator cuff repair 84.36 13.85 108 961520 1543 69965273
Myositis 84.19 13.85 68 961560 17421 69949395
Mental disorder 84.17 13.85 159 961469 28081 69938735
Bundle branch block left 83.91 13.85 19 961609 10380 69956436
Head injury 83.81 13.85 214 961414 33927 69932889
Coma scale abnormal 83.76 13.85 7 961621 8109 69958707
Pulmonary alveolar haemorrhage 83.56 13.85 19 961609 10350 69956466
Decubitus ulcer 83.49 13.85 44 961584 14147 69952669
Onychomycosis 83.46 13.85 244 961384 6657 69960159
Appendicitis 83.16 13.85 63 961565 16670 69950146
Apparent death 83.15 13.85 142 961486 2662 69964154
Dysuria 82.98 13.85 329 961299 45465 69921351
Sleep apnoea syndrome 82.68 13.85 202 961426 32511 69934305
Nocturia 82.55 13.85 31 961597 12173 69954643
Device occlusion 82.27 13.85 21 961607 10574 69956242
Hypoxic-ischaemic encephalopathy 82.25 13.85 4 961624 7304 69959512
Cachexia 82.10 13.85 17 961611 9883 69956933
Pyelonephritis 82.10 13.85 76 961552 18213 69948603
Irritable bowel syndrome 82.07 13.85 1052 960576 49798 69917018
Dermatitis bullous 82.05 13.85 35 961593 12722 69954094
Metastases to lung 82.00 13.85 62 961566 16422 69950394
Incontinence 81.80 13.85 37 961591 12991 69953825
Sarcoidosis 81.77 13.85 236 961392 6391 69960425
Skin fissures 81.59 13.85 336 961292 10934 69955882
Toe operation 81.49 13.85 63 961565 462 69966354
Endodontic procedure 81.27 13.85 133 961495 2404 69964412
Tooth fracture 81.05 13.85 322 961306 10305 69956511
Rotator cuff syndrome 80.93 13.85 365 961263 12369 69954447
Gastric haemorrhage 80.52 13.85 46 961582 14139 69952677
Lower respiratory tract infection 80.44 13.85 2037 959591 109876 69856940
Gastritis erosive 80.36 13.85 19 961609 10076 69956740
Hypogammaglobulinaemia 80.27 13.85 28 961600 11510 69955306
Pericarditis 80.12 13.85 1603 960025 83102 69883714
Cerebral haematoma 80.05 13.85 5 961623 7373 69959443
Swollen tongue 79.99 13.85 247 961381 36799 69930017
Injection site hypoaesthesia 79.77 13.85 58 961570 383 69966433
Weight increased 79.68 13.85 2590 959038 239741 69727075
Graft versus host disease 79.34 13.85 53 961575 14970 69951846
Apathy 79.30 13.85 31 961597 11877 69954939
Elbow operation 79.17 13.85 51 961577 268 69966548
Drug tolerance decreased 79.10 13.85 303 961325 9530 69957286
Pneumonia fungal 78.70 13.85 19 961609 9934 69956882
Hepatitis 78.45 13.85 379 961249 49601 69917215
Lung consolidation 78.40 13.85 10 961618 8296 69958520
Enteritis 78.16 13.85 38 961590 12793 69954023
Coronary artery stenosis 78.06 13.85 30 961598 11614 69955202
Lip swelling 77.91 13.85 221 961407 33833 69932983
Iron deficiency anaemia 77.85 13.85 120 961508 22952 69943864
Bronchitis chronic 77.76 13.85 172 961456 3932 69962884
Muscle injury 77.50 13.85 831 960797 37663 69929153
Vision blurred 77.46 13.85 868 960760 94116 69872700
Vertigo 77.23 13.85 514 961114 62129 69904687
Aplasia pure red cell 77.10 13.85 6 961622 7368 69959448
Elbow deformity 77.07 13.85 97 961531 1361 69965455
Skin ulcer 76.84 13.85 994 960634 47151 69919665
Guttate psoriasis 76.82 13.85 57 961571 390 69966426
General symptom 75.98 13.85 124 961504 2236 69964580
Dental operation 75.95 13.85 82 961546 966 69965850
Muscular weakness 75.69 13.85 1369 960259 136967 69829849
Hypotonia 75.60 13.85 33 961595 11832 69954984
Cholangitis 75.38 13.85 31 961597 11518 69955298
Eye operation 75.27 13.85 110 961518 1794 69965022
Hyperreflexia 75.22 13.85 7 961621 7435 69959381
International normalised ratio decreased 75.07 13.85 8 961620 7630 69959186
Blood pressure diastolic increased 75.02 13.85 37 961591 12354 69954462
Fatigue 74.86 13.85 12486 949142 811833 69154983
Surgical failure 74.83 13.85 73 961555 756 69966060
Protein urine present 74.68 13.85 18 961610 9422 69957394
Scab 73.88 13.85 290 961338 9228 69957588
Memory impairment 73.75 13.85 1710 959918 90931 69875885
Concomitant disease aggravated 73.61 13.85 36 961592 12078 69954738
Injury 73.28 13.85 550 961078 64695 69902121
Hallucinations, mixed 73.18 13.85 3 961625 6359 69960457
Dyspnoea at rest 72.87 13.85 5 961623 6814 69960002
Hypoventilation 72.82 13.85 4 961624 6578 69960238
Blood chloride decreased 72.78 13.85 10 961618 7840 69958976
Device dispensing error 72.67 13.85 35 961593 90 69966726
Deformity 72.02 13.85 262 961366 8035 69958781
Eye infection 71.94 13.85 300 961328 9818 69956998
Oral mucosal exfoliation 71.47 13.85 92 961536 1322 69965494
Nephropathy 71.46 13.85 16 961612 8809 69958007
Embolism 71.08 13.85 44 961584 12944 69953872
Dyspepsia 71.07 13.85 818 960810 88259 69878557
Ischaemic cardiomyopathy 70.97 13.85 7 961621 7097 69959719
Splenomegaly 70.78 13.85 91 961537 18779 69948037
Cardiac tamponade 70.78 13.85 15 961613 8580 69958236
Folliculitis 70.52 13.85 885 960743 41685 69925131
Acute graft versus host disease 70.42 13.85 21 961607 9541 69957275
Hospice care 70.34 13.85 13 961615 8192 69958624
Tachyarrhythmia 70.23 13.85 4 961624 6378 69960438
Brain injury 70.11 13.85 28 961600 10589 69956227
Erectile dysfunction 70.08 13.85 49 961579 13513 69953303
Hepatitis fulminant 69.82 13.85 5 961623 6576 69960240
Vulvovaginal mycotic infection 69.66 13.85 162 961466 3833 69962983
Cytomegalovirus infection reactivation 69.56 13.85 6 961622 6775 69960041
Physical disability 69.48 13.85 133 961495 2734 69964082
Injection site exfoliation 69.48 13.85 37 961591 126 69966690
Blood phosphorus increased 69.42 13.85 6 961622 6764 69960052
Carpal tunnel syndrome 69.24 13.85 432 961196 16625 69950191
Burning sensation 69.23 13.85 1054 960574 51816 69915000
Pneumonia bacterial 69.13 13.85 74 961554 16567 69950249
Clonus 68.76 13.85 4 961624 6264 69960552
Endophthalmitis 68.59 13.85 4 961624 6251 69960565
Wrist deformity 68.49 13.85 104 961524 1758 69965058
Systemic infection 67.99 13.85 6 961622 6651 69960165
Diplopia 67.89 13.85 178 961450 27969 69938847
BK virus infection 67.76 13.85 13 961615 7976 69958840
Synovial cyst 67.57 13.85 266 961362 8476 69958340
Injection site dryness 67.33 13.85 43 961585 222 69966594
Blood culture positive 67.01 13.85 13 961615 7913 69958903
Helicobacter infection 67.00 13.85 1094 960534 54562 69912254
Pneumatosis intestinalis 66.97 13.85 3 961625 5884 69960932
Ischaemia 66.94 13.85 11 961617 7548 69959268
Injection site coldness 66.79 13.85 32 961596 81 69966735
Hiccups 66.45 13.85 20 961608 9032 69957784
Tenderness 66.40 13.85 504 961124 20706 69946110
Hypertonia 65.98 13.85 6 961622 6492 69960324
Wrong product administered 65.92 13.85 16 961612 8335 69958481
Post procedural haemorrhage 65.81 13.85 47 961581 12819 69953997
Brain natriuretic peptide increased 65.79 13.85 15 961613 8156 69958660
Insurance issue 65.53 13.85 150 961478 3511 69963305
Bone swelling 65.32 13.85 92 961536 1448 69965368
Orthopnoea 65.16 13.85 23 961605 9385 69957431
Enthesopathy 64.97 13.85 306 961322 10563 69956253
Intestinal perforation 64.83 13.85 73 961555 15971 69950845
Product substitution issue 64.69 13.85 94 961534 18419 69948397
Nystagmus 64.57 13.85 23 961605 9332 69957484
Paranasal sinus discomfort 64.57 13.85 146 961482 3389 69963427
Incorrect product administration duration 64.51 13.85 33 961595 10791 69956025
Ventricular hypertrophy 64.45 13.85 7 961621 6577 69960239
Metabolic disorder 64.26 13.85 15 961613 8025 69958791
Panniculitis 64.13 13.85 301 961327 10375 69956441
Latent tuberculosis 63.94 13.85 135 961493 2986 69963830
Muscle haemorrhage 63.81 13.85 4 961624 5880 69960936
Renal tubular disorder 63.80 13.85 5 961623 6105 69960711
Duodenal ulcer haemorrhage 63.63 13.85 8 961620 6710 69960106
Benign prostatic hyperplasia 63.50 13.85 31 961597 10412 69956404
Injection site oedema 63.48 13.85 79 961549 1095 69965721
Dental implantation 63.39 13.85 51 961577 399 69966417
Blood phosphorus decreased 63.28 13.85 5 961623 6064 69960752
Aplasia 63.22 13.85 11 961617 7240 69959576
Peripheral ischaemia 63.12 13.85 20 961608 8738 69958078
SLE arthritis 63.06 13.85 55 961573 487 69966329
Cardiovascular disorder 62.94 13.85 80 961548 16590 69950226
Left ventricular failure 62.78 13.85 20 961608 8708 69958108
Liver injury 62.77 13.85 314 961314 40721 69926095
Wheelchair user 62.72 13.85 184 961444 5030 69961786
Non-cardiac chest pain 62.50 13.85 22 961606 8993 69957823
Arthropod sting 62.38 13.85 74 961554 973 69965843
Skin disorder 62.35 13.85 658 960970 29699 69937117
Infusion site swelling 62.20 13.85 6 961622 6192 69960624
Odynophagia 62.19 13.85 30 961598 10145 69956671
Sickle cell anaemia with crisis 62.12 13.85 5 961623 5973 69960843
Device power source issue 62.08 13.85 66 961562 763 69966053
Glycosylated haemoglobin increased 62.06 13.85 87 961541 17304 69949512
Skin exfoliation 61.98 13.85 965 960663 47661 69919155
Gastrointestinal disorder 61.69 13.85 1869 959759 103558 69863258
Systemic candida 61.56 13.85 5 961623 5929 69960887
Blood parathyroid hormone decreased 61.40 13.85 264 961364 8760 69958056
Joint surgery 61.28 13.85 42 961586 249 69966567
Aortic valve incompetence 61.27 13.85 22 961606 8882 69957934
Middle insomnia 61.21 13.85 60 961568 13993 69952823
Granuloma skin 61.21 13.85 236 961392 7446 69959370
Progressive multifocal leukoencephalopathy 61.02 13.85 104 961524 19110 69947706
Sciatica 60.95 13.85 555 961073 24072 69942744
Normal newborn 60.91 13.85 7 961621 6293 69960523
Escherichia bacteraemia 60.74 13.85 5 961623 5864 69960952
Foetal exposure during pregnancy 60.73 13.85 4 961624 5641 69961175
Lymphoma 60.52 13.85 388 961240 15074 69951742
Upper-airway cough syndrome 60.40 13.85 277 961351 9454 69957362
Candida infection 60.36 13.85 251 961377 34222 69932594
Dermatitis exfoliative 60.20 13.85 34 961594 10517 69956299
Occult blood positive 59.86 13.85 8 961620 6405 69960411
Red cell distribution width increased 59.84 13.85 58 961570 13599 69953217
Ammonia increased 59.73 13.85 12 961616 7126 69959690
Embolic stroke 59.46 13.85 13 961615 7276 69959540
Fistula 59.36 13.85 37 961591 10844 69955972
Nerve compression 59.34 13.85 244 961384 7934 69958882
Large intestine perforation 59.03 13.85 55 961573 13140 69953676
Protein total decreased 59.02 13.85 19 961609 8217 69958599
Dementia 58.99 13.85 135 961493 22230 69944586
Proctalgia 58.91 13.85 20 961608 8363 69958453
Dyslipidaemia 58.86 13.85 30 961598 9830 69956986
Joint dislocation 58.34 13.85 367 961261 14164 69952652
Mucormycosis 58.30 13.85 18 961610 7996 69958820
Intracranial pressure increased 58.25 13.85 14 961614 7342 69959474
Paraesthesia oral 58.19 13.85 74 961554 15343 69951473
Venous thrombosis 58.16 13.85 10 961618 6639 69960177
Induration 58.11 13.85 94 961534 1682 69965134
Blister 57.98 13.85 1779 959849 98747 69868069
Catheter site infection 57.92 13.85 7 961621 6053 69960763
Respiratory syncytial virus infection 57.87 13.85 16 961612 7639 69959177
Hiatus hernia 57.85 13.85 125 961503 21009 69945807
Ear congestion 57.69 13.85 109 961519 2218 69964598
Product administration error 57.45 13.85 206 961422 29317 69937499
Serum ferritin increased 57.45 13.85 25 961603 8980 69957836
Hydrocephalus 57.32 13.85 19 961609 8066 69958750
Nail pitting 57.30 13.85 43 961585 300 69966516
Gastric ulcer haemorrhage 57.01 13.85 22 961606 8496 69958320
Dry eye 56.89 13.85 679 960949 31603 69935213
Aortic arteriosclerosis 56.66 13.85 18 961610 7851 69958965
Cerebral atrophy 56.64 13.85 16 961612 7531 69959285
Orthosis user 56.55 13.85 24 961604 40 69966776
Pseudomonal sepsis 56.53 13.85 5 961623 5532 69961284
Prescribed underdose 56.48 13.85 129 961499 21256 69945560
Hyperlactacidaemia 56.37 13.85 3 961625 5069 69961747
Oral herpes 56.31 13.85 538 961090 23648 69943168
Nerve injury 56.24 13.85 243 961385 8081 69958735
Infection susceptibility increased 56.11 13.85 124 961504 2833 69963983
Sinus node dysfunction 56.07 13.85 14 961614 7155 69959661
Necrosis 56.06 13.85 23 961605 8558 69958258
Escherichia infection 56.01 13.85 84 961544 16247 69950569
Gynaecomastia 56 13.85 12 961616 6811 69960005
Major depression 55.98 13.85 23 961605 8551 69958265
Tendon operation 55.90 13.85 39 961589 239 69966577
Electrocardiogram T wave inversion 55.84 13.85 3 961625 5028 69961788
Post procedural infection 55.82 13.85 283 961345 10070 69956746
Duodenal ulcer perforation 55.81 13.85 989 960639 50123 69916693
Pulmonary function test decreased 55.74 13.85 12 961616 6789 69960027
Chronic graft versus host disease 55.37 13.85 12 961616 6758 69960058
Injection site scar 55.23 13.85 59 961569 686 69966130
Catheter site pain 55.02 13.85 3 961625 4965 69961851
Pulmonary fibrosis 55.01 13.85 709 960919 33601 69933215
Supraventricular extrasystoles 54.93 13.85 9 961619 6189 69960627
Genital haemorrhage 54.89 13.85 7 961621 5808 69961008
Retinal haemorrhage 54.87 13.85 18 961610 7692 69959124
Blood chloride increased 54.83 13.85 3 961625 4950 69961866
Immune reconstitution inflammatory syndrome 54.82 13.85 57 961571 12933 69953883
Euphoric mood 54.77 13.85 13 961615 6876 69959940
Neutrophilia 54.77 13.85 15 961613 7206 69959610
Staphylococcal bacteraemia 54.72 13.85 42 961586 11040 69955776
Thrombosis in device 54.71 13.85 4 961624 5171 69961645
Platelet count increased 54.59 13.85 121 961507 20152 69946664
Lip oedema 54.49 13.85 6 961622 5577 69961239
Tenosynovitis 54.27 13.85 350 961278 13626 69953190
Mental impairment 54.24 13.85 94 961534 17161 69949655
Personality disorder 54.05 13.85 6 961622 5542 69961274
Bunion operation 54.03 13.85 62 961566 785 69966031
Alcohol abuse 53.84 13.85 4 961624 5103 69961713
Knee deformity 53.72 13.85 67 961561 931 69965885
Abortion induced 53.67 13.85 12 961616 6613 69960203
Eye movement disorder 53.60 13.85 17 961611 7423 69959393
Stridor 53.44 13.85 4 961624 5072 69961744
Blood thyroid stimulating hormone increased 53.36 13.85 24 961604 8455 69958361
Colorectal cancer 53.27 13.85 24 961604 8446 69958370
Foetal death 53.24 13.85 10 961618 6229 69960587
Dental care 53.17 13.85 60 961568 745 69966071
Electroencephalogram abnormal 53.00 13.85 5 961623 5253 69961563
Coordination abnormal 52.84 13.85 85 961543 15981 69950835
Methaemoglobinaemia 52.67 13.85 3 961625 4783 69962033
Multiple-drug resistance 52.65 13.85 17 961611 7338 69959478
Laryngeal oedema 52.46 13.85 18 961610 7477 69959339
Portal hypertension 52.11 13.85 12 961616 6480 69960336
Depressive symptom 52.03 13.85 5 961623 5176 69961640
Affect lability 51.98 13.85 37 961591 10109 69956707
Papule 51.84 13.85 204 961424 6499 69960317
Obsessive-compulsive disorder 51.83 13.85 6 961622 5364 69961452
Anaemia macrocytic 51.71 13.85 5 961623 5150 69961666
Rhinitis allergic 51.55 13.85 31 961597 9264 69957552
Onychomadesis 51.53 13.85 147 961481 3954 69962862
Renal disorder 51.43 13.85 303 961325 37706 69929110
Nocardiosis 51.38 13.85 5 961623 5124 69961692
Eosinophilic pneumonia 51.26 13.85 4 961624 4901 69961915
Cytomegalovirus test positive 51.11 13.85 7 961621 5501 69961315
Central nervous system lesion 51.04 13.85 56 961572 12397 69954419
Thyroid neoplasm 50.94 13.85 119 961509 2824 69963992
Cytomegalovirus chorioretinitis 50.94 13.85 6 961622 5292 69961524
Gastrointestinal perforation 50.91 13.85 8 961620 5673 69961143
Sensitivity to weather change 50.66 13.85 217 961411 7188 69959628
Bone cyst 50.61 13.85 117 961511 2757 69964059
Drug screen positive 50.61 13.85 9 961619 5831 69960985
Ligament rupture 50.55 13.85 118 961510 2799 69964017
Breath sounds abnormal 50.47 13.85 63 961565 13168 69953648
Clostridium test positive 50.38 13.85 4 961624 4832 69961984
Iron deficiency 50.33 13.85 21 961607 7735 69959081
Oesophageal ulcer 50.18 13.85 13 961615 6481 69960335
Weight fluctuation 49.93 13.85 34 961594 9507 69957309
Fibrin D dimer increased 49.53 13.85 19 961609 7364 69959452
Neutrophil percentage increased 49.52 13.85 3 961625 4539 69962277
Blood glucose decreased 49.42 13.85 165 961463 23994 69942822
C-reactive protein increased 49.19 13.85 1898 959730 108619 69858197
Incoherent 48.68 13.85 19 961609 7287 69959529
Thrombotic thrombocytopenic purpura 48.43 13.85 12 961616 6165 69960651
Neoplasm malignant 48.43 13.85 600 961028 28174 69938642
Oxygen consumption increased 48.40 13.85 4 961624 4676 69962140
Lower limb fracture 48.34 13.85 391 961237 16381 69950435
Congestive cardiomyopathy 48.34 13.85 46 961582 10880 69955936
Diabetes insipidus 48.28 13.85 4 961624 4667 69962149
Tuberculosis 48.28 13.85 356 961272 14492 69952324
Escherichia urinary tract infection 48.12 13.85 60 961568 12547 69954269
Musculoskeletal deformity 48.08 13.85 69 961559 1106 69965710
Abdominal wall haematoma 48.07 13.85 3 961625 4427 69962389
Injection site pustule 48.06 13.85 23 961605 58 69966758
Petit mal epilepsy 48.03 13.85 8 961620 5436 69961380
Depressed mood 47.97 13.85 372 961256 43448 69923368
Drooling 47.94 13.85 8 961620 5428 69961388
Femoral neck fracture 47.93 13.85 32 961596 9041 69957775
Ventricular dysfunction 47.78 13.85 9 961619 5595 69961221
Carotid artery stenosis 47.77 13.85 26 961602 8210 69958606
Joint laxity 47.72 13.85 101 961527 2238 69964578
Device defective 47.54 13.85 79 961549 1447 69965369
Blood creatine increased 47.53 13.85 30 961598 8734 69958082
Rhinovirus infection 47.43 13.85 16 961612 6717 69960099
Periorbital oedema 47.40 13.85 23 961605 7752 69959064
Alcohol poisoning 47.24 13.85 3 961625 4362 69962454
Normochromic normocytic anaemia 47.24 13.85 18 961610 7005 69959811
Diverticulum intestinal 47.21 13.85 25 961603 8016 69958800
Hyperpyrexia 47.19 13.85 8 961620 5366 69961450
Hangnail 47.02 13.85 15 961613 3 69966813
Injection site discharge 46.91 13.85 43 961585 409 69966407
Bone graft 46.86 13.85 52 961576 633 69966183
Stress at work 46.85 13.85 65 961563 1008 69965808
Acute graft versus host disease in skin 46.84 13.85 19 961609 7118 69959698
Application site erythema 46.76 13.85 5 961623 4756 69962060
Arteriospasm coronary 46.66 13.85 12 961616 6012 69960804
Exercise tolerance decreased 46.46 13.85 27 961601 8221 69958595
Renal cyst 46.39 13.85 68 961560 13277 69953539
Product administered at inappropriate site 46.36 13.85 125 961503 3251 69963565
Persecutory delusion 46.33 13.85 4 961624 4513 69962303
Hyperphosphataemia 46.09 13.85 3 961625 4273 69962543
Osteoporosis 46.05 13.85 925 960703 47982 69918834
Rebound effect 46.05 13.85 12 961616 5959 69960857
Atlantoaxial instability 46.04 13.85 36 961592 269 69966547
Fungal infection 46.03 13.85 739 960889 36728 69930088
Hysterectomy 46.02 13.85 174 961454 5438 69961378
Rash macular 45.77 13.85 539 961089 25005 69941811
Fluid intake reduced 45.74 13.85 10 961618 5597 69961219
Lupus-like syndrome 45.72 13.85 290 961338 11225 69955591
Nephrotic syndrome 45.68 13.85 46 961582 10594 69956222
Performance status decreased 45.67 13.85 10 961618 5591 69961225
International normalised ratio abnormal 45.66 13.85 8 961620 5239 69961577
Disease recurrence 45.62 13.85 310 961318 37293 69929523
Blood pressure inadequately controlled 45.56 13.85 10 961618 5582 69961234
Respiration abnormal 45.49 13.85 18 961610 6846 69959970
Atypical femur fracture 45.31 13.85 6 961622 4837 69961979
Intervertebral disc operation 45.18 13.85 58 961570 831 69965985
Laryngeal pain 45.16 13.85 11 961617 5717 69961099
Bedridden 44.99 13.85 281 961347 10817 69955999
Nasal discharge discolouration 44.96 13.85 92 961536 1989 69964827
Human antichimeric antibody positive 44.90 13.85 76 961552 1414 69965402
Blood uric acid increased 44.57 13.85 35 961593 9094 69957722
Lymphocyte percentage decreased 44.52 13.85 6 961622 4773 69962043
Tinnitus 44.50 13.85 297 961331 35879 69930937
Malignant melanoma 44.47 13.85 332 961296 13568 69953248
Hypoglycaemic coma 44.35 13.85 4 961624 4357 69962459
Pneumonia cytomegaloviral 44.26 13.85 5 961623 4556 69962260
Bacterial test positive 44.10 13.85 20 961608 7011 69959805
Prostatic specific antigen increased 44.09 13.85 38 961590 9428 69957388
Autonomic nervous system imbalance 44.08 13.85 4 961624 4335 69962481
Logorrhoea 44.01 13.85 3 961625 4111 69962705
Pathological fracture 44.00 13.85 39 961589 9544 69957272
Rash morbilliform 43.95 13.85 10 961618 5445 69961371
Systemic lupus erythematosus rash 43.85 13.85 79 961549 1548 69965268
Duodenitis 43.79 13.85 20 961608 6982 69959834
Nervousness 43.72 13.85 628 961000 30492 69936324
Red blood cells urine positive 43.66 13.85 6 961622 4703 69962113
Haemothorax 43.62 13.85 8 961620 5069 69961747
Urinary tract infection 43.60 13.85 2846 958782 245923 69720893
Breast cancer metastatic 43.41 13.85 44 961584 10102 69956714
Subileus 43.30 13.85 9 961619 5218 69961598
Thirst 43.20 13.85 83 961545 14566 69952250
Lacunar infarction 42.89 13.85 12 961616 5684 69961132
Portal vein thrombosis 42.86 13.85 10 961618 5352 69961464
Self-medication 42.79 13.85 5 961623 4438 69962378
Culture urine positive 42.79 13.85 4 961624 4233 69962583
Scleritis 42.79 13.85 127 961501 3495 69963321
Bilirubin conjugated increased 42.75 13.85 9 961619 5172 69961644
Spider vein 42.73 13.85 30 961598 186 69966630
Encephalitis 42.71 13.85 74 961554 13511 69953305
Transplant rejection 42.70 13.85 405 961223 17766 69949050
Body temperature abnormal 42.53 13.85 86 961542 1843 69964973
Lipodystrophy acquired 42.52 13.85 4 961624 4212 69962604
Mineral metabolism disorder 42.51 13.85 35 961593 284 69966532
Spinal stenosis 42.45 13.85 342 961286 14311 69952505
Leukoencephalopathy 42.35 13.85 23 961605 7271 69959545
Intraventricular haemorrhage 42.27 13.85 5 961623 4396 69962420
Eczema 42.23 13.85 276 961352 33505 69933311
Staphylococcus test positive 42.20 13.85 14 961614 5940 69960876
Personality change 42.06 13.85 35 961593 8835 69957981
Conjunctival haemorrhage 42.02 13.85 10 961618 5280 69961536
Gastrointestinal necrosis 42.01 13.85 9 961619 5109 69961707
Hepatorenal syndrome 42.00 13.85 3 961625 3954 69962862
Hernia repair 41.98 13.85 84 961544 1786 69965030
Refusal of treatment by patient 41.95 13.85 32 961596 8438 69958378
Neurological decompensation 41.94 13.85 7 961621 4749 69962067
Pseudomembranous colitis 41.93 13.85 9 961619 5102 69961714
Dislocation of vertebra 41.91 13.85 154 961474 4746 69962070
Skin injury 41.89 13.85 107 961521 2691 69964125
Exposure to communicable disease 41.87 13.85 43 961585 476 69966340
Cardiac operation 41.82 13.85 144 961484 4295 69962521
Blood immunoglobulin E increased 41.79 13.85 7 961621 4737 69962079
Colonoscopy 41.70 13.85 81 961547 1684 69965132
Somnambulism 41.67 13.85 10 961618 5250 69961566
Rheumatoid lung 41.54 13.85 122 961506 3337 69963479
Polyarthritis 41.54 13.85 269 961359 10487 69956329
Haemolytic uraemic syndrome 41.44 13.85 4 961624 4126 69962690
Staphylococcal sepsis 41.43 13.85 74 961554 13353 69953463
Inadequate analgesia 41.34 13.85 4 961624 4118 69962698
Sudden cardiac death 41.32 13.85 8 961620 4877 69961939
Exposure via skin contact 41.25 13.85 32 961596 236 69966580
Sleep disorder 40.95 13.85 1239 960389 68633 69898183
Compartment syndrome 40.93 13.85 6 961622 4480 69962336
Glaucoma 40.91 13.85 400 961228 17692 69949124
Retching 40.91 13.85 98 961530 15881 69950935
Breast cancer stage II 40.74 13.85 11 961617 5335 69961481
Faecal calprotectin increased 40.67 13.85 6 961622 4459 69962357
Hepatocellular carcinoma 40.64 13.85 47 961581 10161 69956655
Spinal instability 40.60 13.85 37 961591 349 69966467
Phlebitis 40.53 13.85 31 961597 8163 69958653
Mean cell volume increased 40.48 13.85 13 961615 5631 69961185
Post transplant lymphoproliferative disorder 40.44 13.85 50 961578 10495 69956321
Dermatitis acneiform 40.35 13.85 37 961591 8908 69957908
Skin swelling 40.09 13.85 113 961515 3018 69963798
Spinal laminectomy 39.82 13.85 44 961584 533 69966283
Scar 39.79 13.85 325 961303 13656 69953160
Animal scratch 39.75 13.85 63 961565 1107 69965709
Night sweats 39.74 13.85 822 960806 42862 69923954
Cardiac murmur 39.58 13.85 65 961563 12121 69954695
Paralysis 39.58 13.85 64 961564 12008 69954808
Burn infection 39.49 13.85 16 961612 22 69966794
Injection site anaesthesia 39.49 13.85 16 961612 22 69966794
Cerebellar syndrome 39.42 13.85 11 961617 5220 69961596
Skin hyperpigmentation 39.24 13.85 21 961607 6694 69960122
Bradyarrhythmia 39.21 13.85 4 961624 3949 69962867
Gangrene 39.14 13.85 33 961595 8276 69958540
Neoplasm recurrence 39.06 13.85 4 961624 3937 69962879
Bacterial sepsis 39.03 13.85 28 961600 7619 69959197
Flank pain 39.00 13.85 115 961513 17387 69949429
Tumour haemorrhage 39.00 13.85 3 961625 3719 69963097
Atrial tachycardia 38.97 13.85 3 961625 3717 69963099
Body height below normal 38.86 13.85 82 961546 1813 69965003
Pulmonary arterial pressure increased 38.77 13.85 6 961622 4303 69962513
Prescribed overdose 38.76 13.85 213 961415 26968 69939848
Epstein-Barr virus infection 38.73 13.85 75 961553 13123 69953693
Eyelid ptosis 38.64 13.85 48 961580 10054 69956762
Mass excision 38.64 13.85 34 961594 305 69966511
Lung transplant 38.54 13.85 6 961622 4284 69962532
Foot fracture 38.47 13.85 421 961207 19179 69947637
Hyperventilation 38.42 13.85 25 961603 7161 69959655
Fungaemia 38.32 13.85 5 961623 4077 69962739
Vaginal haemorrhage 38.29 13.85 144 961484 20208 69946608
Blood sodium increased 38.28 13.85 7 961621 4445 69962371
Haemarthrosis 38.18 13.85 13 961615 5426 69961390
Areflexia 38.18 13.85 11 961617 5111 69961705
Microcytic anaemia 38.15 13.85 9 961619 4780 69962036
Gout 38.14 13.85 171 961457 22835 69943981
Disturbance in social behaviour 38.14 13.85 5 961623 4062 69962754
Ocular icterus 38.12 13.85 12 961616 5265 69961551
Throat tightness 37.96 13.85 192 961436 24830 69941986
Hospitalisation 37.96 13.85 841 960787 81727 69885089
Product distribution issue 37.92 13.85 58 961570 987 69965829
Blood calcium increased 37.35 13.85 40 961588 8953 69957863
Pyelonephritis acute 37.34 13.85 14 961614 5503 69961313
Ovarian neoplasm 37.26 13.85 43 961585 548 69966268
Spinal disorder 37.10 13.85 233 961395 8987 69957829
Spinal compression fracture 37.02 13.85 99 961529 15454 69951362
Menopause 36.95 13.85 78 961550 1725 69965091
Loose body in joint 36.84 13.85 64 961564 1217 69965599
Thrombophlebitis 36.84 13.85 17 961611 5899 69960917
Generalised oedema 36.81 13.85 160 961468 21548 69945268
Aortic stenosis 36.78 13.85 22 961606 6594 69960222
Visual field defect 36.78 13.85 36 961592 8402 69958414
Cyst removal 36.77 13.85 37 961591 399 69966417
Anal fistula 36.73 13.85 18 961610 6032 69960784
Head discomfort 36.67 13.85 302 961326 12721 69954095
Blood thyroid stimulating hormone decreased 36.65 13.85 14 961614 5440 69961376
Extrasystoles 36.64 13.85 24 961604 6850 69959966
Bursitis 36.57 13.85 536 961092 26137 69940679
High density lipoprotein decreased 36.46 13.85 6 961622 4113 69962703
Peripheral arterial occlusive disease 36.39 13.85 29 961599 7480 69959336
Troponin I increased 36.33 13.85 6 961622 4102 69962714
Urine analysis abnormal 36.32 13.85 19 961609 6135 69960681
Sacroiliitis 36.07 13.85 112 961516 3161 69963655
Prostate infection 35.94 13.85 42 961586 543 69966273
Diffuse large B-cell lymphoma recurrent 35.87 13.85 3 961625 3473 69963343
Craniocerebral injury 35.84 13.85 9 961619 4582 69962234
Ligament operation 35.81 13.85 13 961615 10 69966806
Contrast media allergy 35.78 13.85 89 961539 2201 69964615
Hepatosplenomegaly 35.76 13.85 16 961612 5654 69961162
Dysaesthesia 35.70 13.85 14 961614 5354 69961462
Low density lipoprotein increased 35.63 13.85 34 961594 8031 69958785
Autoimmune hepatitis 35.54 13.85 57 961571 10729 69956087
Cystitis 35.37 13.85 860 960768 46081 69920735
Urine leukocyte esterase positive 35.36 13.85 4 961624 3641 69963175
Nephrolithiasis 35.36 13.85 866 960762 46457 69920359
Obstruction 35.31 13.85 4 961624 3637 69963179
Cell death 35.27 13.85 7 961621 4193 69962623
Tenoplasty 35.20 13.85 18 961610 55 69966761
Intervertebral disc space narrowing 35.18 13.85 70 961558 1482 69965334
Urinary bladder suspension 35.17 13.85 21 961607 94 69966722
Limb injury 35.11 13.85 517 961111 25235 69941581
Vitreous haemorrhage 35.05 13.85 3 961625 3409 69963407
Nephrogenic anaemia 35.03 13.85 4 961624 3614 69963202
Accident 34.99 13.85 193 961435 7098 69959718
Injection site hyperaesthesia 34.96 13.85 17 961611 45 69966771
Lyme disease 34.80 13.85 102 961526 2787 69964029
Communication disorder 34.78 13.85 5 961623 3789 69963027
Ulcer 34.71 13.85 516 961112 25238 69941578
Faeces soft 34.36 13.85 26 961602 6884 69959932
Sputum culture positive 34.32 13.85 3 961625 3351 69963465
Escherichia sepsis 34.27 13.85 31 961597 7512 69959304
Stenotrophomonas infection 34.26 13.85 3 961625 3346 69963470
Product dose omission in error 34.25 13.85 10 961618 4606 69962210
Dilatation ventricular 34.19 13.85 6 961622 3925 69962891
Alcoholism 34.15 13.85 9 961619 4436 69962380
Non-small cell lung cancer 34.05 13.85 22 961606 6325 69960491
Abnormal dreams 34.03 13.85 57 961571 10546 69956270
Adrenal insufficiency 34.01 13.85 201 961427 24994 69941822
Premature labour 33.88 13.85 35 961593 7965 69958851
Lung opacity 33.79 13.85 5 961623 3708 69963108
Mouth haemorrhage 33.77 13.85 54 961574 10177 69956639
Haemoperitoneum 33.74 13.85 7 961621 4064 69962752
Oral candidiasis 33.71 13.85 199 961429 24753 69942063
Dilatation atrial 33.71 13.85 4 961624 3508 69963308
Scar excision 33.71 13.85 17 961611 50 69966766
Neck mass 33.68 13.85 129 961499 4057 69962759
Skin papilloma 33.64 13.85 154 961474 5252 69961564
Restless legs syndrome 33.63 13.85 132 961496 18296 69948520
Enterobacter infection 33.61 13.85 7 961621 4053 69962763
Pulmonary sarcoidosis 33.61 13.85 60 961568 1167 69965649
Pollakiuria 33.46 13.85 291 961337 33170 69933646
Hyperaesthesia teeth 33.43 13.85 71 961557 1577 69965239
Diarrhoea haemorrhagic 33.26 13.85 68 961560 11662 69955154
Nasal ulcer 33.25 13.85 75 961553 1738 69965078
Bicytopenia 33.23 13.85 7 961621 4021 69962795
Lack of injection site rotation 33.15 13.85 33 961595 351 69966465
Therapy partial responder 33.14 13.85 75 961553 12399 69954417
Malabsorption 33.06 13.85 11 961617 4659 69962157
Anal haemorrhage 33.05 13.85 6 961622 3830 69962986
Jugular vein thrombosis 33.02 13.85 7 961621 4003 69962813
Laryngospasm 32.94 13.85 5 961623 3638 69963178
Breast cancer stage I 32.94 13.85 21 961607 6081 69960735
Social avoidant behaviour 32.91 13.85 11 961617 4645 69962171
Adenovirus infection 32.88 13.85 34 961594 7734 69959082
Herpes simplex 32.81 13.85 64 961564 11168 69955648
Paraparesis 32.77 13.85 5 961623 3624 69963192
Pain of skin 32.73 13.85 245 961383 10021 69956795
Diverticulum 32.71 13.85 87 961541 13606 69953210
Oesophageal varices haemorrhage 32.66 13.85 6 961622 3797 69963019
Wound dehiscence 32.65 13.85 22 961606 6186 69960630
Device breakage 32.56 13.85 48 961580 9350 69957466
Focal dyscognitive seizures 32.53 13.85 4 961624 3413 69963403
Anger 32.44 13.85 111 961517 16021 69950795
Deafness transitory 32.15 13.85 51 961577 897 69965919
Sexual dysfunction 32.13 13.85 26 961602 6655 69960161
Clostridial infection 32.13 13.85 16 961612 5313 69961503
Liver transplant 32.10 13.85 9 961619 4257 69962559
Cardiopulmonary failure 32.03 13.85 24 961604 6386 69960430
Conjunctival hyperaemia 32.00 13.85 8 961620 4085 69962731
Eating disorder 31.99 13.85 136 961492 18429 69948387
Acute psychosis 31.91 13.85 7 961621 3909 69962907
Thrombocytosis 31.91 13.85 35 961593 7749 69959067
Trigger finger 31.77 13.85 117 961511 3610 69963206
Panic attack 31.72 13.85 173 961455 21946 69944870
Meniscus operation 31.62 13.85 23 961605 152 69966664
Endocarditis 31.50 13.85 54 961574 9900 69956916
Skin reaction 31.47 13.85 310 961318 13739 69953077
Spinal column injury 31.35 13.85 78 961550 1929 69964887
Neurological symptom 31.30 13.85 33 961595 7440 69959376
Injection site plaque 31.30 13.85 18 961610 74 69966742
Pneumonia klebsiella 31.21 13.85 11 961617 4493 69962323
Facial paralysis 31.20 13.85 150 961478 19658 69947158
Infected bite 31.19 13.85 68 961560 1539 69965277
Pharyngeal swelling 31.17 13.85 25 961603 6428 69960388
Frustration tolerance decreased 31.09 13.85 177 961451 6588 69960228
Epicondylitis 31.09 13.85 77 961551 1899 69964917
White blood cells urine positive 31.01 13.85 19 961609 5621 69961195
Hypercalcaemia 30.95 13.85 307 961321 34078 69932738
Urinary tract infection bacterial 30.89 13.85 18 961610 5473 69961343
Arthritis infective 30.88 13.85 189 961439 7223 69959593
Visual impairment 30.85 13.85 1357 960271 78893 69887923
Gastrointestinal sounds abnormal 30.81 13.85 15 961613 5046 69961770
Mammoplasty 30.79 13.85 27 961601 241 69966575
Rib fracture 30.77 13.85 209 961419 25147 69941669
Ingrown hair 30.75 13.85 41 961587 611 69966205
Neurogenic bladder 30.70 13.85 7 961621 3806 69963010
Blood iron abnormal 30.47 13.85 57 961571 1151 69965665
Macular oedema 30.38 13.85 16 961612 5146 69961670
Sunburn 30.35 13.85 112 961516 3459 69963357
Injection site infection 30.34 13.85 76 961552 1888 69964928
Pulmonary function test abnormal 30.29 13.85 5 961623 3420 69963396
Artificial crown procedure 30.27 13.85 26 961602 225 69966591
Swelling of eyelid 30.26 13.85 3 961625 3029 69963787
Abdominal tenderness 30.25 13.85 54 961574 9746 69957070
Lymph node pain 30.24 13.85 63 961565 1380 69965436
Anaphylactoid reaction 30.24 13.85 15 961613 4992 69961824
Upper limb fracture 30.16 13.85 343 961285 15776 69951040
Hearing aid user 30.01 13.85 15 961613 43 69966773
Extravasation 29.95 13.85 5 961623 3392 69963424
Reaction to preservatives 29.93 13.85 23 961605 167 69966649
Sputum increased 29.88 13.85 9 961619 4063 69962753
Venous injury 29.87 13.85 42 961586 660 69966156
Mesenteritis 29.85 13.85 27 961601 252 69966564
Epidural injection 29.83 13.85 9 961619 0 69966816
False positive tuberculosis test 29.82 13.85 12 961616 16 69966800
Rocky mountain spotted fever 29.82 13.85 13 961615 24 69966792
Psychiatric decompensation 29.69 13.85 3 961625 2984 69963832
Exposed bone in jaw 29.63 13.85 6 961622 3543 69963273
Diffuse alveolar damage 29.54 13.85 5 961623 3358 69963458
Product physical issue 29.54 13.85 7 961621 3707 69963109
Disability assessment scale score increased 29.49 13.85 3 961625 2968 69963848
Cast application 29.48 13.85 11 961617 10 69966806
Oesophageal carcinoma 29.46 13.85 51 961577 9315 69957501
Type IV hypersensitivity reaction 29.46 13.85 6 961622 3529 69963287
Psychiatric symptom 29.36 13.85 28 961600 6616 69960200
Megacolon 29.31 13.85 4 961624 3152 69963664
Periodontitis 29.26 13.85 11 961617 4317 69962499
Adjustment disorder 29.16 13.85 4 961624 3140 69963676
Prothrombin time shortened 29.13 13.85 3 961625 2939 69963877
Meningitis cryptococcal 29.12 13.85 5 961623 3323 69963493
Pharyngitis 29.11 13.85 412 961216 19939 69946877
Tonsillectomy 28.87 13.85 36 961592 500 69966316
Rhonchi 28.85 13.85 7 961621 3648 69963168
Acute graft versus host disease in intestine 28.80 13.85 8 961620 3808 69963008
Kidney fibrosis 28.78 13.85 5 961623 3295 69963521
Rheumatic fever 28.76 13.85 366 961262 17294 69949522
Body height decreased 28.71 13.85 38 961590 7745 69959071
Multiple allergies 28.71 13.85 192 961436 7568 69959248
Gastric disorder 28.68 13.85 622 961006 32700 69934116
Coronary artery occlusion 28.64 13.85 99 961529 14246 69952570
Intestinal sepsis 28.59 13.85 44 961584 753 69966063
Product administered to patient of inappropriate age 28.52 13.85 15 961613 4828 69961988
Secondary immunodeficiency 28.46 13.85 3 961625 2886 69963930
Application site pain 28.43 13.85 12 961616 4390 69962426
Upper respiratory tract inflammation 28.41 13.85 9 961619 3933 69962883
Arterial occlusive disease 28.36 13.85 38 961590 7704 69959112
Hepatic enzyme abnormal 28.32 13.85 164 961464 6143 69960673
Arthroscopic surgery 28.29 13.85 14 961614 39 69966777
Multiple injuries 28.23 13.85 6 961622 3425 69963391
Injection site scab 28.17 13.85 29 961599 322 69966494
Ear discomfort 28.09 13.85 189 961439 7465 69959351
Myoglobin blood increased 27.97 13.85 4 961624 3043 69963773
Viral infection 27.92 13.85 700 960928 37691 69929125
Amnesia 27.92 13.85 518 961110 51637 69915179
Hereditary angioedema 27.88 13.85 17 961611 5042 69961774
Monocyte count decreased 27.87 13.85 4 961624 3035 69963781
Drug effective for unapproved indication 27.82 13.85 14 961614 4621 69962195
Movement disorder 27.76 13.85 202 961426 23927 69942889
Injection site erosion 27.68 13.85 19 961609 113 69966703
JC virus infection 27.65 13.85 7 961621 3544 69963272
Focal segmental glomerulosclerosis 27.63 13.85 5 961623 3199 69963617
Internal haemorrhage 27.59 13.85 42 961586 8074 69958742
Procedural haemorrhage 27.56 13.85 13 961615 4454 69962362
Bone lesion 27.56 13.85 20 961608 5410 69961406
Cardiac dysfunction 27.48 13.85 7 961621 3530 69963286
Urinary hesitation 27.47 13.85 8 961620 3691 69963125
Hepatitis toxic 27.44 13.85 14 961614 4585 69962231
Acute lymphocytic leukaemia 27.40 13.85 21 961607 5524 69961292
Spondylitis 27.38 13.85 106 961522 3351 69963465
Prescription drug used without a prescription 27.36 13.85 4 961624 2993 69963823
Urinary tract obstruction 27.30 13.85 12 961616 4285 69962531
Self-injurious ideation 27.13 13.85 6 961622 3332 69963484
Enteritis infectious 27.13 13.85 5 961623 3157 69963659
Brain abscess 27.09 13.85 14 961614 4552 69962264
Seronegative arthritis 27.08 13.85 104 961524 3275 69963541
Dizziness postural 27.07 13.85 62 961566 10206 69956610
Pneumonia pseudomonal 27.05 13.85 19 961609 5227 69961589
Diabetic nephropathy 27.01 13.85 3 961625 2770 69964046
Muscle swelling 26.99 13.85 43 961585 759 69966057
Stillbirth 26.87 13.85 9 961619 3796 69963020
Malignant pleural effusion 26.85 13.85 5 961623 3134 69963682
Metastases to meninges 26.82 13.85 5 961623 3131 69963685
Blood immunoglobulin G decreased 26.81 13.85 4 961624 2948 69963868
Peripheral motor neuropathy 26.77 13.85 5 961623 3127 69963689
Calciphylaxis 26.74 13.85 7 961621 3466 69963350
Vascular pseudoaneurysm 26.70 13.85 6 961622 3295 69963521
Tonsillar ulcer 26.69 13.85 31 961597 398 69966418
Conduction disorder 26.60 13.85 5 961623 3113 69963703
Nasal polyps 26.57 13.85 14 961614 4502 69962314
Intracardiac thrombus 26.52 13.85 10 961618 3917 69962899
Abdominal abscess 26.50 13.85 30 961598 6548 69960268
Linear IgA disease 26.47 13.85 4 961624 2920 69963896
Ear disorder 26.36 13.85 105 961523 3364 69963452
Tendonitis 26.30 13.85 434 961194 21688 69945128
Fibrosis 26.20 13.85 17 961611 4877 69961939
Cold sweat 26.14 13.85 130 961498 16886 69949930
Acute abdomen 26.10 13.85 4 961624 2890 69963926
Pneumonia staphylococcal 25.97 13.85 15 961613 4583 69962233
Blood parathyroid hormone increased 25.95 13.85 6 961622 3231 69963585
Injection related reaction 25.94 13.85 42 961586 752 69966064
Paradoxical drug reaction 25.94 13.85 31 961597 6605 69960211
Haemorrhoidal haemorrhage 25.87 13.85 26 961602 5993 69960823
Proctitis 25.87 13.85 8 961620 3550 69963266
Miliaria 25.86 13.85 57 961571 1300 69965516
Idiopathic pulmonary fibrosis 25.77 13.85 17 961611 4834 69961982
Hypokinesia 25.75 13.85 135 961493 17297 69949519
Hyperthermia malignant 25.62 13.85 3 961625 2658 69964158
Ligament disorder 25.60 13.85 27 961601 309 69966507
Pneumomediastinum 25.56 13.85 7 961621 3363 69963453
Fracture 25.41 13.85 162 961466 19782 69947034
Metastases to peritoneum 25.33 13.85 10 961618 3809 69963007
Weight bearing difficulty 25.31 13.85 92 961536 2820 69963996
Gastric perforation 25.29 13.85 10 961618 3805 69963011
Prosthesis user 25.14 13.85 15 961613 67 69966749
PO2 decreased 25.13 13.85 4 961624 2810 69964006
Anticipatory anxiety 25.06 13.85 47 961581 951 69965865
Local reaction 25.04 13.85 34 961594 516 69966300
Cytomegalovirus colitis 25.01 13.85 13 961615 4213 69962603
Escherichia test positive 24.99 13.85 5 961623 2978 69963838
Ependymoma malignant 24.99 13.85 10 961618 13 69966803
Streptococcal bacteraemia 24.97 13.85 6 961622 3147 69963669
Pulmonary sepsis 24.84 13.85 7 961621 3300 69963516
Tendon disorder 24.79 13.85 163 961465 6388 69960428
Hypertensive heart disease 24.78 13.85 11 961617 3905 69962911
Angle closure glaucoma 24.71 13.85 4 961624 2775 69964041
Intentional dose omission 24.65 13.85 170 961458 6771 69960045
Subcutaneous haematoma 24.60 13.85 3 961625 2576 69964240
Autoimmune haemolytic anaemia 24.53 13.85 42 961586 7704 69959112
Thyroiditis 24.51 13.85 12 961616 4024 69962792
Alanine aminotransferase abnormal 24.39 13.85 190 961438 7869 69958947
Hyperparathyroidism secondary 24.34 13.85 3 961625 2555 69964261
Plantar fasciitis 24.33 13.85 96 961532 3062 69963754
Device related sepsis 24.32 13.85 25 961603 5703 69961113
Vascular purpura 24.31 13.85 4 961624 2742 69964074
Paresis 24.28 13.85 11 961617 3859 69962957
Hypopnoea 24.26 13.85 8 961620 3407 69963409
Injection site cellulitis 24.21 13.85 61 961567 1521 69965295
Lichenoid keratosis 24.18 13.85 9 961619 3554 69963262
Eye pruritus 24.04 13.85 304 961324 14343 69952473
Sensory disturbance 24.03 13.85 101 961527 13731 69953085
Eyelid oedema 23.97 13.85 90 961538 12637 69954179
Diabetic retinopathy 23.97 13.85 5 961623 2892 69963924
Wisdom teeth removal 23.96 13.85 29 961599 390 69966426
Biliary colic 23.93 13.85 10 961618 3680 69963136
Spinal cord compression 23.92 13.85 27 961601 5901 69960915
Arthroscopy 23.89 13.85 32 961596 479 69966337
Squamous cell carcinoma of skin 23.88 13.85 90 961538 12622 69954194
Pancreatic carcinoma 23.82 13.85 92 961536 12812 69954004
Dissociation 23.82 13.85 8 961620 3368 69963448
Middle ear effusion 23.80 13.85 75 961553 2134 69964682
Anion gap increased 23.80 13.85 7 961621 3209 69963607
Basal cell carcinoma 23.79 13.85 612 961016 33086 69933730
Varices oesophageal 23.74 13.85 23 961605 5394 69961422
Blood creatine phosphokinase MB increased 23.72 13.85 4 961624 2693 69964123
Enterocolitis infectious 23.68 13.85 4 961624 2690 69964126
Blindness 23.67 13.85 201 961427 23026 69943790
Optic ischaemic neuropathy 23.65 13.85 4 961624 2688 69964128
Mucosal disorder 23.59 13.85 7 961621 3191 69963625
Fixed eruption 23.57 13.85 3 961625 2493 69964323
Folate deficiency 23.54 13.85 6 961622 3024 69963792
Livedo reticularis 23.51 13.85 11 961617 3787 69963029
Thinking abnormal 23.50 13.85 84 961544 11967 69954849
Tumour marker increased 23.47 13.85 11 961617 3783 69963033
Urine abnormality 23.47 13.85 44 961584 7794 69959022
Gastric bypass 23.44 13.85 50 961578 1114 69965702
Venous thrombosis limb 23.44 13.85 13 961615 4062 69962754
Bipolar disorder 23.41 13.85 42 961586 7566 69959250
Haemoglobin increased 23.29 13.85 25 961603 5590 69961226
Investigation abnormal 23.23 13.85 66 961562 1771 69965045
Mycobacterium tuberculosis complex test 23.20 13.85 7 961621 0 69966816
Hepatitis B reactivation 23.17 13.85 23 961605 5332 69961484
Hypertensive emergency 23.16 13.85 3 961625 2460 69964356
Liver abscess 23.14 13.85 25 961603 5574 69961242
Concomitant disease progression 23.14 13.85 8 961620 3307 69963509
Precancerous cells present 23.11 13.85 48 961580 1049 69965767
Cryptococcosis 23.08 13.85 8 961620 3302 69963514
Needle issue 23.08 13.85 238 961390 10677 69956139
Peptic ulcer 23.08 13.85 26 961602 5687 69961129
Initial insomnia 23.07 13.85 31 961597 6278 69960538
Mole excision 22.94 13.85 16 961612 98 69966718
Cartilage injury 22.89 13.85 56 961572 1370 69965446
Psychotic symptom 22.86 13.85 3 961625 2435 69964381
Epstein-Barr virus associated lymphoproliferative disorder 22.85 13.85 8 961620 3281 69963535
Type I hypersensitivity 22.81 13.85 11 961617 3721 69963095
Tonsillitis 22.77 13.85 152 961476 5988 69960828
Procalcitonin increased 22.74 13.85 4 961624 2612 69964204
Oesophageal candidiasis 22.72 13.85 51 961577 8456 69958360
Large intestinal ulcer 22.72 13.85 16 961612 4396 69962420
Ankle arthroplasty 22.69 13.85 50 961578 1140 69965676
Mallory-Weiss syndrome 22.68 13.85 4 961624 2607 69964209
Pneumonia influenzal 22.67 13.85 4 961624 2606 69964210
Acinetobacter infection 22.59 13.85 4 961624 2600 69964216
Electric shock 22.55 13.85 50 961578 1145 69965671
Aortic dissection 22.53 13.85 12 961616 3835 69962981
Eyelid exfoliation 22.50 13.85 17 961611 120 69966696
Bronchiectasis 22.49 13.85 127 961501 15970 69950846
Hepatic lesion 22.43 13.85 30 961598 6087 69960729
Biliary dyskinesia 22.38 13.85 3 961625 2396 69964420
Hepatitis B virus test positive 22.35 13.85 30 961598 450 69966366
Polydipsia 22.33 13.85 29 961599 5959 69960857
Mean cell haemoglobin concentration decreased 22.31 13.85 14 961614 4089 69962727
Eye inflammation 22.29 13.85 139 961489 5348 69961468
Nail discolouration 22.27 13.85 84 961544 2622 69964194
Alcohol use 22.26 13.85 18 961610 4609 69962207
Extremity necrosis 22.20 13.85 6 961622 2908 69963908
Joint injection 22.12 13.85 8 961620 6 69966810
Large intestinal stenosis 22.10 13.85 4 961624 2559 69964257
Oesophageal pain 22.06 13.85 12 961616 3790 69963026
Meningitis aseptic 22.03 13.85 33 961595 6386 69960430
Manufacturing product shipping issue 22.01 13.85 15 961613 88 69966728
CD4 lymphocytes decreased 21.96 13.85 4 961624 2547 69964269
Right ventricular dysfunction 21.95 13.85 3 961625 2361 69964455
Infected cyst 21.94 13.85 48 961580 1089 69965727
Accident at work 21.90 13.85 45 961583 976 69965840
Ischaemic cerebral infarction 21.86 13.85 3 961625 2354 69964462
Abdominal operation 21.85 13.85 32 961596 523 69966293
Hyporeflexia 21.82 13.85 9 961619 3338 69963478
Migraine 21.79 13.85 1193 960435 71045 69895771
Synovial disorder 21.78 13.85 47 961581 1056 69965760
Central venous catheterisation 21.73 13.85 7 961621 3026 69963790
Hypoproteinaemia 21.69 13.85 11 961617 3615 69963201
Choking 21.63 13.85 77 961551 10983 69955833
Pre-eclampsia 21.62 13.85 34 961594 6451 69960365
Resuscitation 21.61 13.85 3 961625 2334 69964482
Idiopathic intracranial hypertension 21.59 13.85 6 961622 2855 69963961
X-ray abnormal 21.51 13.85 80 961548 2480 69964336
Lymphadenopathy 21.48 13.85 837 960791 47954 69918862
Muscle twitching 21.38 13.85 169 961459 19658 69947158
Angiopathy 21.36 13.85 35 961593 6532 69960284
Micturition urgency 21.32 13.85 80 961548 11234 69955582
Thyroid cancer 21.32 13.85 131 961497 5014 69961802
Insomnia 21.17 13.85 2607 959021 215199 69751617
Motor dysfunction 21.16 13.85 98 961530 12972 69953844
Mean cell haemoglobin increased 21.14 13.85 11 961617 3562 69963254
Quadriparesis 21.12 13.85 8 961620 3125 69963691
Musculoskeletal injury 21.12 13.85 18 961610 154 69966662
Metastases to lymph nodes 21.09 13.85 60 961568 9178 69957638
Pulmonary infarction 21.06 13.85 10 961618 3413 69963403
Essential hypertension 21.03 13.85 26 961602 5458 69961358
Bladder operation 21.00 13.85 39 961589 783 69966033
Bursa removal 20.85 13.85 9 961619 16 69966800
Haematocrit increased 20.81 13.85 12 961616 3670 69963146
Metabolic surgery 20.77 13.85 45 961583 1014 69965802
Trismus 20.75 13.85 23 961605 5068 69961748
Syringe issue 20.71 13.85 25 961603 5303 69961513
Ototoxicity 20.70 13.85 7 961621 2934 69963882
Amenorrhoea 20.67 13.85 39 961589 6891 69959925
Oligohydramnios 20.66 13.85 9 961619 3231 69963585
Hypoaesthesia oral 20.65 13.85 91 961537 12209 69954607
Bursa disorder 20.62 13.85 21 961607 230 69966586
Hostility 20.61 13.85 3 961625 2252 69964564
Galactorrhoea 20.58 13.85 10 961618 3368 69963448
Spinal nerve stimulator implantation 20.56 13.85 14 961614 82 69966734
Abnormal faeces 20.49 13.85 36 961592 6537 69960279
Subacute cutaneous lupus erythematosus 20.37 13.85 9 961619 3204 69963612
Periorbital swelling 20.30 13.85 3 961625 2227 69964589
Suicidal behaviour 20.28 13.85 8 961620 3048 69963768
Infiltration anaesthesia 20.26 13.85 17 961611 142 69966674
Swollen joint count increased 20.26 13.85 279 961349 13421 69953395
SARS-CoV-2 test positive 20.25 13.85 56 961572 8645 69958171
Exposure to toxic agent 20.16 13.85 33 961595 6161 69960655
Tic 20.13 13.85 6 961622 2727 69964089
Dermatitis exfoliative generalised 20.11 13.85 35 961593 6379 69960437
Cerebrovascular disorder 20.11 13.85 12 961616 3601 69963215
Gastrointestinal oedema 20.04 13.85 4 961624 2386 69964430
Hyperleukocytosis 19.95 13.85 3 961625 2198 69964618
Myelopathy 19.88 13.85 17 961611 4234 69962582
Eosinophil count decreased 19.86 13.85 7 961621 2859 69963957
Varicella zoster virus infection 19.86 13.85 16 961612 4104 69962712
Dysphoria 19.83 13.85 19 961609 4479 69962337
Blood glucose fluctuation 19.83 13.85 34 961594 6233 69960583
Amyotrophic lateral sclerosis 19.82 13.85 61 961567 1713 69965103
Human herpesvirus 6 infection 19.75 13.85 22 961606 4837 69961979
Oesophageal operation 19.74 13.85 8 961620 11 69966805
Hyperaemia 19.69 13.85 7 961621 2844 69963972
Butterfly rash 19.69 13.85 53 961575 1377 69965439
Bronchial obstruction 19.67 13.85 5 961623 2525 69964291
Gastric infection 19.64 13.85 95 961533 3316 69963500
Hypochromic anaemia 19.64 13.85 5 961623 2522 69964294
Reversible cerebral vasoconstriction syndrome 19.59 13.85 6 961622 2679 69964137
Post procedural haematoma 19.54 13.85 4 961624 2344 69964472
Wrong technique in device usage process 19.53 13.85 94 961534 3274 69963542
Urinary sediment present 19.53 13.85 4 961624 2343 69964473
Klebsiella sepsis 19.47 13.85 7 961621 2824 69963992
Limb crushing injury 19.46 13.85 19 961609 197 69966619
Superinfection 19.45 13.85 17 961611 4189 69962627
Peripheral coldness 19.40 13.85 116 961512 14384 69952432
Peripheral vascular disorder 19.38 13.85 47 961581 7585 69959231
Procedural complication 19.30 13.85 46 961582 7468 69959348
Seasonal allergy 19.29 13.85 273 961355 13211 69953605
Loss of libido 19.29 13.85 5 961623 2492 69964324
Bile duct stone 19.29 13.85 25 961603 5141 69961675
Viraemia 19.23 13.85 5 961623 2487 69964329
Gastric operation 19.22 13.85 21 961607 251 69966565
Gastrointestinal stoma complication 19.21 13.85 4 961624 2316 69964500
Scarlet fever 19.19 13.85 14 961614 93 69966723
Bone deformity 19.19 13.85 23 961605 306 69966510
Nail operation 19.18 13.85 30 961598 521 69966295
Glycosuria 19.15 13.85 3 961625 2132 69964684
Multiple fractures 19.11 13.85 157 961471 6608 69960208
Red blood cell sedimentation rate 19.09 13.85 123 961505 4787 69962029
Optic neuropathy 19.06 13.85 10 961618 3223 69963593
Immobile 19.05 13.85 152 961476 6342 69960474
Ankle fracture 18.98 13.85 303 961325 15041 69951775
Dactylitis 18.95 13.85 70 961558 2163 69964653
Dyschezia 18.93 13.85 6 961622 2621 69964195
Organ failure 18.85 13.85 14 961614 3742 69963074
Bladder repair 18.81 13.85 11 961617 47 69966769
Malignant neoplasm of conjunctiva 18.81 13.85 11 961617 47 69966769
Coronavirus infection 18.81 13.85 35 961593 6217 69960599
Enuresis 18.76 13.85 8 961620 2909 69963907
Increased appetite 18.75 13.85 77 961551 10536 69956280
Toxoplasmosis 18.74 13.85 6 961622 2604 69964212
Gastrointestinal motility disorder 18.73 13.85 29 961599 5537 69961279
Serum sickness 18.73 13.85 11 961617 3330 69963486
Hypercoagulation 18.68 13.85 7 961621 2752 69964064
Anal fissure 18.66 13.85 35 961593 6198 69960618
Nail psoriasis 18.62 13.85 28 961600 469 69966347
Hyperparathyroidism 18.60 13.85 9 961619 3038 69963778
Pancreatitis necrotising 18.60 13.85 11 961617 3317 69963499
Bruxism 18.58 13.85 14 961614 3715 69963101
Metastatic renal cell carcinoma 18.58 13.85 8 961620 2892 69963924
Tendon injury 18.53 13.85 61 961567 1777 69965039
Mucous stools 18.50 13.85 16 961612 3963 69962853
Limb mass 18.47 13.85 92 961536 3250 69963566
Prostatic operation 18.45 13.85 19 961609 211 69966605
Mechanical ventilation 18.41 13.85 6 961622 2575 69964241
Oral pain 18.39 13.85 280 961348 28786 69938030
Tendon sheath incision 18.37 13.85 10 961618 36 69966780
Differentiation syndrome 18.34 13.85 4 961624 2243 69964573
Premature baby 18.34 13.85 12 961616 3427 69963389
Urinary bladder haemorrhage 18.34 13.85 5 961623 2409 69964407
Diabetic neuropathy 18.33 13.85 32 961596 5826 69960990
Cytology abnormal 18.31 13.85 23 961605 322 69966494
Intra-abdominal fluid collection 18.31 13.85 8 961620 2867 69963949
Hepatitis B 18.31 13.85 53 961575 8061 69958755
Precancerous skin lesion 18.31 13.85 46 961582 1145 69965671
Neutrophil count abnormal 18.30 13.85 10 961618 3151 69963665
Peripheral sensorimotor neuropathy 18.27 13.85 7 961621 2715 69964101
Affective disorder 18.26 13.85 47 961581 7432 69959384
Tonic convulsion 18.26 13.85 3 961625 2059 69964757
Uterine dilation and curettage 18.24 13.85 28 961600 478 69966338
Pruritus allergic 18.15 13.85 44 961584 1070 69965746
Red blood cell sedimentation rate decreased 18.05 13.85 19 961609 217 69966599
Cataract 17.99 13.85 925 960703 54720 69912096
Actinic keratosis 17.99 13.85 30 961598 5560 69961256
Skin sensitisation 17.90 13.85 37 961591 806 69966010
Skin atrophy 17.89 13.85 126 961502 5053 69961763
Apraxia 17.84 13.85 7 961621 2676 69964140
Hepatic cyst 17.83 13.85 30 961598 5541 69961275
Bite 17.76 13.85 27 961601 457 69966359
Staphylococcal infection 17.73 13.85 890 960738 52514 69914302
Product use issue 17.70 13.85 2152 959476 177785 69789031
Coronary artery thrombosis 17.62 13.85 9 961619 2946 69963870
Application site rash 17.62 13.85 3 961625 2006 69964810
Intervertebral disc compression 17.60 13.85 42 961586 1011 69965805
Pancreatitis chronic 17.57 13.85 15 961613 3739 69963077
Swelling face 17.55 13.85 689 960939 62475 69904341
Bone density abnormal 17.55 13.85 82 961546 2821 69963995
Paraplegia 17.55 13.85 23 961605 4707 69962109
Discontinued product administered 17.49 13.85 11 961617 55 69966761
Pharyngeal operation 17.49 13.85 6 961622 3 69966813
Road traffic accident 17.46 13.85 604 961024 34078 69932738
Oropharyngeal discomfort 17.44 13.85 35 961593 6044 69960772
Retinal toxicity 17.42 13.85 49 961579 1307 69965509
Aphonia 17.37 13.85 197 961431 9054 69957762
Laryngeal disorder 17.37 13.85 40 961588 940 69965876
Chest X-ray abnormal 17.36 13.85 45 961583 7099 69959717
Neck deformity 17.36 13.85 58 961570 1703 69965113
Mononucleosis syndrome 17.36 13.85 14 961614 110 69966706
Lacrimation increased 17.30 13.85 372 961256 19527 69947289
Skin irritation 17.27 13.85 208 961420 9701 69957115
Hepatic cancer 17.26 13.85 70 961558 9613 69957203
Injection site streaking 17.23 13.85 10 961618 42 69966774
Haemoglobin abnormal 17.22 13.85 38 961590 6339 69960477
Neuroma 17.20 13.85 19 961609 230 69966586
Continuous haemodiafiltration 17.20 13.85 3 961625 1971 69964845
Infusion site bruising 17.16 13.85 3 961625 1968 69964848
Tinea pedis 17.12 13.85 67 961561 2129 69964687
Large intestinal haemorrhage 17.11 13.85 7 961621 2609 69964207
Cerebellar infarction 17.05 13.85 13 961615 3429 69963387
Whipple's disease 17.04 13.85 8 961620 19 69966797
Cardiovascular insufficiency 17.00 13.85 8 961620 2745 69964071
Peritoneal dialysis complication 16.99 13.85 5 961623 2291 69964525
Carbon dioxide decreased 16.95 13.85 11 961617 3155 69963661
Rebound psoriasis 16.92 13.85 17 961611 183 69966633
Nervous system disorder 16.90 13.85 228 961400 23918 69942898
Vaginal operation 16.88 13.85 6 961622 4 69966812
Hypersensitivity pneumonitis 16.86 13.85 13 961615 3409 69963407
Body tinea 16.82 13.85 49 961579 1334 69965482
Drug eruption 16.79 13.85 675 960953 38821 69927995
Product container seal issue 16.77 13.85 12 961616 77 69966739
Polycystic ovaries 16.76 13.85 9 961619 2863 69963953
Pneumoperitoneum 16.72 13.85 9 961619 2860 69963956
Unintended pregnancy 16.68 13.85 12 961616 3261 69963555
Rheumatoid factor 16.68 13.85 14 961614 117 69966699
Device alarm issue 16.67 13.85 3 961625 1927 69964889
Hypertonic bladder 16.65 13.85 16 961612 3767 69963049
Respiratory symptom 16.63 13.85 16 961612 3765 69963051
Vitamin B12 deficiency 16.61 13.85 35 961593 5937 69960879
Troponin T increased 16.61 13.85 7 961621 2563 69964253
Tumour pain 16.60 13.85 4 961624 2094 69964722
Single functional kidney 16.59 13.85 14 961614 118 69966698
Flat affect 16.59 13.85 3 961625 1920 69964896
Rheumatoid nodule removal 16.57 13.85 5 961623 0 69966816
Neurectomy 16.57 13.85 5 961623 0 69966816
Regurgitation 16.53 13.85 5 961623 2251 69964565
Contrast media reaction 16.50 13.85 3 961625 1913 69964903
Intervertebral disc injury 16.50 13.85 15 961613 141 69966675
Laser therapy 16.50 13.85 8 961620 21 69966795
Cholecystectomy 16.44 13.85 182 961446 8315 69958501
Spondyloarthropathy 16.40 13.85 38 961590 897 69965919
Guillain-Barre syndrome 16.38 13.85 55 961573 7985 69958831
Device use issue 16.37 13.85 5 961623 2237 69964579
Facial paresis 16.37 13.85 27 961601 5026 69961790
Erosive oesophagitis 16.35 13.85 8 961620 2683 69964133
In vitro fertilisation 16.34 13.85 11 961617 63 69966753
Body temperature increased 16.29 13.85 413 961215 39421 69927395
Ureteric obstruction 16.27 13.85 7 961621 2532 69964284
Allergic sinusitis 16.27 13.85 27 961601 494 69966322
Hot flush 16.25 13.85 530 961098 49054 69917762
Monoparesis 16.20 13.85 12 961616 3212 69963604
Chorioretinopathy 16.18 13.85 5 961623 2220 69964596
Libido decreased 16.18 13.85 26 961602 4890 69961926
Intervertebral disc disorder 16.10 13.85 112 961516 4473 69962343
Prostate cancer metastatic 16.10 13.85 18 961610 3951 69962865
Adrenocortical insufficiency acute 16.08 13.85 8 961620 2658 69964158
Accidental exposure to product by child 16.07 13.85 9 961619 2797 69964019
Limb reconstructive surgery 16.06 13.85 10 961618 49 69966767
Muscle atrophy 16.06 13.85 79 961549 10291 69956525
Cold-stimulus headache 16.03 13.85 7 961621 13 69966803
Sensory loss 16 13.85 90 961538 11329 69955487
Gingival injury 15.99 13.85 8 961620 23 69966793
Stem cell transplant 15.97 13.85 15 961613 3570 69963246
Coagulation time prolonged 15.94 13.85 5 961623 2199 69964617
Transaminases abnormal 15.93 13.85 34 961594 758 69966058
Oral infection 15.92 13.85 124 961504 5135 69961681
Episcleritis 15.92 13.85 39 961589 955 69965861
Blood creatinine abnormal 15.87 13.85 22 961606 4397 69962419
Retinal detachment 15.87 13.85 60 961568 8407 69958409
Allergic oedema 15.87 13.85 33 961595 722 69966094
Blood creatinine decreased 15.86 13.85 49 961579 7300 69959516
Septic embolus 15.83 13.85 3 961625 1857 69964959
Anal abscess 15.81 13.85 59 961569 8299 69958517
Myasthenia gravis 15.79 13.85 49 961579 7290 69959526
Anaesthetic complication 15.76 13.85 8 961620 2628 69964188
Joint ankylosis 15.75 13.85 52 961576 1517 69965299
Pelvic venous thrombosis 15.74 13.85 3 961625 1849 69964967
Disease complication 15.72 13.85 23 961605 4494 69962322
Melkersson-Rosenthal syndrome 15.70 13.85 7 961621 14 69966802
Unmasking of previously unidentified disease 15.68 13.85 3 961625 1844 69964972
Overwork 15.60 13.85 10 961618 52 69966764
Sensitisation 15.56 13.85 7 961621 2466 69964350
Synovial rupture 15.55 13.85 21 961607 317 69966499
Biliary obstruction 15.54 13.85 19 961609 4008 69962808
Vestibular disorder 15.51 13.85 6 961622 2314 69964502
Nail bed disorder 15.50 13.85 18 961610 231 69966585
Viral haemorrhagic cystitis 15.49 13.85 3 961625 1828 69964988
Cellulitis 15.45 13.85 1143 960485 97785 69869031
Gingival bleeding 15.44 13.85 132 961496 15100 69951716
Defaecation urgency 15.42 13.85 24 961604 4573 69962243
Small intestinal perforation 15.38 13.85 11 961617 2998 69963818
Acute sinusitis 15.35 13.85 21 961607 4220 69962596
Oesophageal stenosis 15.34 13.85 19 961609 3985 69962831
Thrombocytopenic purpura 15.34 13.85 6 961622 2298 69964518
Intentional underdose 15.32 13.85 5 961623 2144 69964672
Steroid diabetes 15.26 13.85 11 961617 2986 69963830
Traumatic haematoma 15.25 13.85 4 961624 1978 69964838
Large intestine polyp 15.25 13.85 92 961536 11384 69955432
Normocytic anaemia 15.24 13.85 16 961612 3614 69963202
Abdominal pain upper 15.18 13.85 2348 959280 191254 69775562
Product taste abnormal 15.18 13.85 5 961623 2131 69964685
Labile blood pressure 15.13 13.85 5 961623 2127 69964689
Thyroid operation 15.11 13.85 15 961613 159 69966657
Splenic infarction 15.09 13.85 14 961614 3352 69963464
Papilloedema 15.09 13.85 36 961592 5842 69960974
Prolonged labour 15.05 13.85 24 961604 424 69966392
Disease susceptibility 15.05 13.85 20 961608 297 69966519
Streptococcal infection 14.96 13.85 168 961460 7703 69959113
Polychondritis 14.95 13.85 27 961601 530 69966286
Skin candida 14.94 13.85 3 961625 1782 69965034
Spinal meningioma benign 14.90 13.85 12 961616 94 69966722
Ingrowing nail 14.87 13.85 70 961558 2416 69964400
Presbyacusis 14.86 13.85 73 961555 2564 69964252
Intervertebral discitis 14.83 13.85 102 961526 4059 69962757
Terminal state 14.82 13.85 111 961517 4541 69962275
Staphylococcal skin infection 14.80 13.85 47 961581 1343 69965473
Large intestinal obstruction 14.76 13.85 11 961617 2935 69963881
Genital abscess 14.75 13.85 15 961613 164 69966652
Organising pneumonia 14.75 13.85 78 961550 9972 69956844
Hair disorder 14.75 13.85 38 961590 961 69965855
Synovectomy 14.71 13.85 17 961611 217 69966599
Foaming at mouth 14.69 13.85 3 961625 1761 69965055
Fallopian tube cancer 14.66 13.85 8 961620 29 69966787
Mucosal erosion 14.65 13.85 5 961623 2084 69964732
Dysphonia 14.64 13.85 825 960803 49275 69917541
Hair colour changes 14.63 13.85 19 961609 3904 69962912
Needle track marks 14.63 13.85 10 961618 59 69966757
Immunosuppression 14.62 13.85 228 961400 11264 69955552
Inflammatory marker increased 14.59 13.85 191 961437 9083 69957733
Body temperature fluctuation 14.59 13.85 16 961612 3543 69963273
Chorea 14.53 13.85 5 961623 2073 69964743
Cerebral venous thrombosis 14.50 13.85 8 961620 2507 69964309
HLA marker study positive 14.48 13.85 13 961615 120 69966696
Sciatic nerve neuropathy 14.48 13.85 21 961607 340 69966476
Vitreous detachment 14.47 13.85 5 961623 2068 69964748
Dry skin 14.45 13.85 911 960717 55020 69911796
Enterocolitis haemorrhagic 14.42 13.85 5 961623 2063 69964753
Strabismus 14.40 13.85 7 961621 2357 69964459
Gastrointestinal inflammation 14.39 13.85 45 961583 6678 69960138
Infarction 14.37 13.85 22 961606 4220 69962596
Polymyalgia rheumatica 14.31 13.85 19 961609 3867 69962949
Blood alkaline phosphatase decreased 14.27 13.85 3 961625 1726 69965090
Papilloma excision 14.26 13.85 5 961623 3 69966813
Substance-induced psychotic disorder 14.25 13.85 12 961616 3011 69963805
Abdominoplasty 14.24 13.85 10 961618 62 69966754
Labour complication 14.24 13.85 10 961618 62 69966754
Bronchial hyperreactivity 14.23 13.85 9 961619 2617 69964199
Maculopathy 14.23 13.85 9 961619 2617 69964199
Invasive breast carcinoma 14.20 13.85 26 961602 516 69966300
Eructation 14.18 13.85 76 961552 9684 69957132
Pre-existing condition improved 14.18 13.85 29 961599 4973 69961843
Monocyte percentage increased 14.16 13.85 5 961623 2040 69964776
Temperature regulation disorder 14.16 13.85 24 961604 4420 69962396
Labelled drug-disease interaction medication error 14.16 13.85 19 961609 285 69966531
Vocal cord paralysis 14.16 13.85 7 961621 2334 69964482
Breast mass 14.12 13.85 130 961498 5655 69961161
Retinopathy 14.11 13.85 16 961612 3490 69963326
Lymphoedema 14.09 13.85 91 961537 11078 69955738
Blood urea decreased 14.08 13.85 11 961617 2866 69963950
Oral mucosal roughening 14.02 13.85 7 961621 20 69966796
Corneal infection 14.00 13.85 10 961618 64 69966752
Opportunistic infection 13.99 13.85 10 961618 2726 69964090
Tumour necrosis factor receptor-associated periodic syndrome 13.98 13.85 11 961617 83 69966733
General physical condition abnormal 13.96 13.85 38 961590 5898 69960918
Libido increased 13.96 13.85 4 961624 1865 69964951
Pulse abnormal 13.95 13.85 11 961617 2852 69963964
Breast operation 13.91 13.85 18 961610 260 69966556
Compression fracture 13.90 13.85 39 961589 5992 69960824

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L04AB01 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
IMMUNOSUPPRESSANTS
IMMUNOSUPPRESSANTS
Tumor necrosis factor alpha (TNF-alpha) inhibitors
FDA MoA N0000175451 Tumor Necrosis Factor Receptor Blocking Activity
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D007155 Immunologic Factors
MeSH PA D007166 Immunosuppressive Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents
FDA EPC N0000175610 Tumor Necrosis Factor Blocker

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Ankylosing spondylitis indication 9631008 DOID:7147
Psoriasis with arthropathy indication 33339001
Rheumatoid arthritis indication 69896004 DOID:7148
Plaque psoriasis indication 200965009
Juvenile idiopathic arthritis indication 410502007
Sepsis contraindication 91302008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Tumor necrosis factor Cytokine INHIBITOR DRUG LABEL DRUG LABEL

External reference:

IDSource
OP401G7OJC UNII
D00742 KEGG_DRUG
4021136 VUID
N0000148590 NUI
C0717758 UMLSCUI
CHEBI:4875 CHEBI
CHEMBL1201572 ChEMBL_ID
DB00005 DRUGBANK_ID
D000068800 MESH_DESCRIPTOR_UI
7783 INN_ID
6789 IUPHAR_LIGAND_ID
2103480 RXNORM
13915 MMSL
33391 MMSL
7788 MMSL
d04365 MMSL
007673 NDDF
016975 NDDF
118259007 SNOMEDCT_US
387045004 SNOMEDCT_US
4021136 VANDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 50090-3531 SOLUTION 50 mg SUBCUTANEOUS BLA 32 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 50090-4490 SOLUTION 50 mg SUBCUTANEOUS BLA 29 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 50090-4590 SOLUTION 50 mg SUBCUTANEOUS BLA 32 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-010 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-010 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-010 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-021 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-021 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-021 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-032 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-032 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-032 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-044 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-044 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-044 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-055 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-055 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-055 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-435 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-435 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-435 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-445 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-445 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-445 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-446 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-446 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-446 SOLUTION 50 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-455 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-455 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections
ENBREL HUMAN PRESCRIPTION DRUG LABEL 1 58406-455 SOLUTION 25 mg SUBCUTANEOUS BLA 33 sections