iguratimod Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
immunomodulators, both stimulant/suppressive and stimulant 4894 123663-49-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • kolbet
  • iguratimod
  • careram
  • T-614
a methanesulfonanilide disease-modifying antirheumatic drug that has been developed exclusively in Japan and China
  • Molecular weight: 374.37
  • Formula: C17H14N2O6S
  • CLOGP: 1.93
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 2
  • TPSA: 110.80
  • ALOGS: -3.75
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
June 29, 2012 PMDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Rheumatoid arthritis indication 69896004 DOID:7148

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.64 acidic
pKa2 9.55 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01146 KEGG_DRUG
4IHY34Y2NV UNII
8176 INN_ID
C519076 MESH_SUPPLEMENTAL_RECORD_UI
DB12233 DRUGBANK_ID
CHEBI:31689 CHEBI
CHEMBL2107455 ChEMBL_ID
124246 PUBCHEM_CID
9736 IUPHAR_LIGAND_ID

Pharmaceutical products:

None