clevudine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
uridine derivatives used as antiviral agents and as antineoplastics 4394 163252-36-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • clevudine
  • levovir
  • Molecular weight: 260.22
  • Formula: C10H13FN2O5
  • CLOGP: -0.94
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 99.10
  • ALOGS: -0.47
  • ROTB: 2

Drug dosage:

DoseUnitRoute
30 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J05AF12 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIVIRALS FOR SYSTEMIC USE
DIRECT ACTING ANTIVIRALS
Nucleoside and nucleotide reverse transcriptase inhibitors
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000998 Antiviral Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Chronic type B viral hepatitis indication 61977001




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.46 acidic
pKa2 11.79 acidic
pKa3 13.23 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03537 KEGG_DRUG
C0045212 UMLSCUI
CHEBI:135964 CHEBI
CHEMBL458875 ChEMBL_ID
DB06683 DRUGBANK_ID
C034935 MESH_SUPPLEMENTAL_RECORD_UI
7684 INN_ID
IN51MVP5F1 UNII
73115 PUBCHEM_CID

Pharmaceutical products:

None