magnesium citrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4281 3344-18-1

Description:

MoleculeDescription

Synonyms:

  • magnesium citrate
  • citric acid magnesium salt
  • trimagnesium dicitrate
  • Molecular weight: 451.11
  • Formula: C12H10Mg3O14
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 140.62
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Rhonchi 44.86 18.78 13 3361 2294 50599456
Tetany 39.98 18.78 11 3363 1610 50600140
Focal segmental glomerulosclerosis 37.28 18.78 10 3364 1331 50600419
Constipation 28.26 18.78 47 3327 185661 50416089
Gastrooesophageal reflux disease 26.61 18.78 29 3345 76399 50525351
Hyperaesthesia 22.62 18.78 11 3363 8162 50593588

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Constipation 28.58 21.01 30 1287 114130 29459080
Burkholderia test positive 23.48 21.01 6 1311 993 29572217
Device related infection 22.91 21.01 12 1305 15624 29557586

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Constipation 43.76 17.21 60 3699 229277 64265696
Rhonchi 41.37 17.21 13 3746 3450 64491523
Tetany 38.25 17.21 11 3748 2161 64492812
Focal segmental glomerulosclerosis 22.92 17.21 8 3751 2936 64492037
Gastrooesophageal reflux disease 19.29 17.21 24 3735 83119 64411854
Device related infection 18.74 17.21 15 3744 30611 64464362

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A06AD19 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Osmotically acting laxatives
ATC A12CC04 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
OTHER MINERAL SUPPLEMENTS
Magnesium
ATC B05CB03 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
IRRIGATING SOLUTIONS
Salt solutions
MeSH PA D002400 Cathartics
MeSH PA D005765 Gastrointestinal Agents
CHEBI has role CHEBI:50503 laxante

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Constipation indication 14760008 DOID:2089
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Incomplete passage of stool indication 249515001
Peptic ulcer contraindication 13200003 DOID:750
Hyperkalemia contraindication 14140009
Hyperphosphatemia contraindication 20165001 DOID:0050459
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Chronic heart failure contraindication 48447003
Metabolic acidosis contraindication 59455009
Diarrhea contraindication 62315008
Hypercalcemia contraindication 66931009 DOID:12678
Hypermagnesemia contraindication 66978005
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Appendicitis contraindication 74400008 DOID:8337
Gastrointestinal hemorrhage contraindication 74474003
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Gastrointestinal obstruction contraindication 126765001
Impaired renal function disorder contraindication 197663003
Gastroparesis contraindication 235675006
Rhabdomyolysis contraindication 240131006
Esophageal dysmotility contraindication 266434009 DOID:9192
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Primary adrenocortical insufficiency contraindication 373662000
Ketoacidosis in diabetes mellitus contraindication 420422005 DOID:1837
Esophageal Compression contraindication
Genitourinary Tract Infections contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019514 VUID
N0000147634 NUI
D03265 KEGG_DRUG
4019514 VANDF
C0126774 UMLSCUI
CHEBI:131391 CHEBI
CHEMBL3989480 ChEMBL_ID
DB11110 DRUGBANK_ID
C110422 MESH_SUPPLEMENTAL_RECORD_UI
RHO26O1T9V UNII
6099959 PUBCHEM_CID
52356 RXNORM
28364 MMSL
5011 MMSL
5563 MMSL
d01008 MMSL
001185 NDDF
006958 NDDF
008279 NDDF
12495006 SNOMEDCT_US
387052002 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0015 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citratesaline laxative HUMAN OTC DRUG LABEL 1 0363-0328 LIQUID 1.75 g ORAL OTC MONOGRAPH NOT FINAL 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0629 LIQUID 1.75 g ORAL OTC MONOGRAPH NOT FINAL 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0667 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0667 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
citroma HUMAN OTC DRUG LABEL 1 0363-0693 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-7162 LIQUID 1.75 g ORAL OTC monograph not final 13 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-7162 LIQUID 1.75 g ORAL OTC monograph not final 13 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8162 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8166 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8166 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0166 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0166 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma HUMAN OTC DRUG LABEL 1 0869-0525 LIQUID 1.75 g ORAL OTC monograph not final 12 sections
Citroma HUMAN OTC DRUG LABEL 1 0869-0667 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma HUMAN OTC DRUG LABEL 1 0869-0667 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma Magnesium Citrate HUMAN OTC DRUG LABEL 1 0869-0686 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma Magnesium Citrate HUMAN OTC DRUG LABEL 1 0869-0686 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0693 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0904-6304 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
citroma HUMAN OTC DRUG LABEL 1 0904-6304 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
Saline Laxative HUMAN OTC DRUG LABEL 1 0904-6787 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 11673-164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 11673-164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 11673-179 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Magnesium CitrateLemon HUMAN OTC DRUG LABEL 1 11673-329 LIQUID 1.75 g ORAL OTC MONOGRAPH NOT FINAL 16 sections