isoxepac 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-inflammatory agents, ibufenac derivatives 3310 55453-87-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • isoxepac
  • artil
Non-steroidal arylacetic acid derivative anti-inflammatory with analgesic and antipyretic activity
  • Molecular weight: 268.27
  • Formula: C16H12O4
  • CLOGP: 2.97
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 63.60
  • ALOGS: -3.94
  • ROTB: 2

Drug dosage:

None

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 2 Hosey CM, Chan R, Benet LZ

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Disease of liver contraindication 235856003 DOID:409




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.43 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04638 KEGG_DRUG
C0064103 UMLSCUI
CHEBI:135102 CHEBI
CHEMBL33211 ChEMBL_ID
C014904 MESH_SUPPLEMENTAL_RECORD_UI
41448 PUBCHEM_CID
4246 INN_ID
2KH283Q0Z5 UNII

Pharmaceutical products:

None