homosalate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3279 118-56-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • homosalate
  • homomenthyl salicylate
  • kemester
cpd not photoallergenic
  • Molecular weight: 262.35
  • Formula: C16H22O3
  • CLOGP: 5.92
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 46.53
  • ALOGS: -3.85
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Macular degeneration 504.14 21.44 114 1722 14274 50589014
Drug ineffective 95.92 21.44 131 1705 819202 49784086
Chronic sinusitis 28.28 21.44 10 1826 6135 50597153
Paraesthesia oral 28.06 21.44 12 1824 12209 50591079
Jarisch-Herxheimer reaction 25.75 21.44 5 1831 290 50602998
Dermatophytosis 22.15 21.44 4 1832 156 50603132

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Macular degeneration 31.69 18.15 11 2612 5699 64490410
Pyrexia 25.33 18.15 64 2559 558580 63937529
Chronic sinusitis 23.31 18.15 9 2614 6283 64489826
Paraesthesia oral 22.83 18.15 11 2612 13120 64482989
Jarisch-Herxheimer reaction 20.97 18.15 5 2618 682 64495427

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D003358 Cosmetics
MeSH PA D003879 Dermatologic Agents
MeSH PA D020011 Protective Agents
MeSH PA D011837 Radiation-Protective Agents
MeSH PA D013473 Sunscreening Agents

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.91 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4021147 VUID
N0000179485 NUI
D04450 KEGG_DRUG
4021147 VANDF
C0304631 UMLSCUI
CHEBI:91642 CHEBI
CHEMBL1377575 ChEMBL_ID
DB11064 DRUGBANK_ID
C060446 MESH_SUPPLEMENTAL_RECORD_UI
8362 PUBCHEM_CID
3183 INN_ID
V06SV4M95S UNII
91326 RXNORM
001969 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 50 Sunscreen HUMAN OTC DRUG LABEL 4 0023-5501 LOTION 60 mg TOPICAL OTC monograph not final 8 sections
Solbar Thirty SPF 30 HUMAN OTC DRUG LABEL 5 0096-0685 CREAM 0.12 g TOPICAL OTC monograph final 8 sections
Solbar Avo SPF35 HUMAN OTC DRUG LABEL 4 0096-0687 CREAM 0.08 g TOPICAL OTC monograph final 8 sections
Solbar Zinc SPF38 HUMAN OTC DRUG LABEL 3 0096-0688 CREAM 0.10 1 TOPICAL OTC monograph final 8 sections
Daily Facial MoisturizerSPF 25 HUMAN OTC DRUG LABEL 4 0096-0721 CREAM 0.06 g TOPICAL OTC monograph final 11 sections
Cetaphil Daily Facial Moisturizer with suncreen SPF 35 HUMAN OTC DRUG LABEL 4 0299-4113 LOTION 95 mg TOPICAL OTC monograph final 12 sections
Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 HUMAN OTC DRUG LABEL 4 0299-4118 LOTION 125 mg TOPICAL OTC monograph final 12 sections
Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 HUMAN OTC DRUG LABEL 4 0299-4118 LOTION 125 mg TOPICAL OTC monograph final 12 sections
Almay Anti Aging Lip Care SPF 20 HUMAN OTC DRUG LABEL 5 0311-0709 LIPSTICK 5 mg TOPICAL OTC monograph final 8 sections
Almay Best Blend Forever Makeup HUMAN OTC DRUG LABEL 4 0311-0719 LOTION 3.50 mg TOPICAL OTC monograph final 5 sections
Almay Healthy Biome Makeup HUMAN OTC DRUG LABEL 5 0311-0723 EMULSION 5 mg TOPICAL OTC monograph final 7 sections
Hydrating Antioxidant Moiturizer HUMAN OTC DRUG LABEL 4 0363-0540 CREAM 4.72 g TOPICAL OTC monograph not final 11 sections
WALGREEN SPORT SPF 70 SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0900 LOTION 100 mg TOPICAL OTC monograph not final 12 sections
WALGREENS SPORT SPF 50 SUNSCREEN HUMAN OTC DRUG LABEL 4 0363-0924 AEROSOL, SPRAY 100 mg TOPICAL OTC monograph not final 13 sections
WALGREENS BROAD SPECTRUM SPF 110 AGE PROTECTION SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0933 LOTION 150 mg TOPICAL OTC monograph not final 12 sections
WALGREENS BROAD SPECTRUM SPF 70 SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0936 STICK 150 mg TOPICAL OTC monograph not final 11 sections
WALGREENS SPORT BROAD SPECTRUM SPF 50 FACES SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0937 LOTION 130 mg TOPICAL OTC monograph not final 13 sections
WALGREENS BROAD SPECTRUM SPF 30 DRY TOUCH SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0940 LOTION 70 mg TOPICAL OTC monograph not final 13 sections
WALGREENS BROAD SPECTRUM SPORT SPF 50 SUNSCREEN HUMAN OTC DRUG LABEL 4 0363-0943 LOTION 100 mg TOPICAL OTC monograph not final 12 sections
Walgreens Sport SPF 50 HUMAN OTC DRUG LABEL 5 0363-0956 SPRAY 100 mg TOPICAL OTC monograph not final 12 sections
Walgreens SPF55 Sunscreen HUMAN OTC DRUG LABEL 4 0363-0961 STICK 150 mg TOPICAL OTC monograph not final 12 sections
Walgreens SPF 55 Dry Touch HUMAN OTC DRUG LABEL 5 0363-0963 LOTION 100 mg TOPICAL OTC monograph not final 12 sections
Walgreens Dry Touch Broad Spectrum SPF 55 HUMAN OTC DRUG LABEL 4 0363-0965 LOTION 100 mg TOPICAL OTC monograph not final 11 sections
Walgreens SPF 30 Hydrating Continuous HUMAN OTC DRUG LABEL 3 0363-0970 AEROSOL, SPRAY 70 mg TOPICAL OTC monograph not final 11 sections
Walgreens SPF55 Sunscreen Reef-Conscious Formula HUMAN OTC DRUG LABEL 4 0363-0976 STICK 150 mg TOPICAL OTC monograph not final 12 sections
Walgreens SPF 50 Clear Complexion For Face HUMAN OTC DRUG LABEL 5 0363-0981 LOTION 40 mg TOPICAL OTC monograph not final 11 sections
Walgreens Sport SPF 30 HUMAN OTC DRUG LABEL 5 0363-0991 SPRAY 100 mg TOPICAL OTC monograph not final 13 sections
Well at Walgreens Kids Sunscreen Broad Spectrum SPF 50 HUMAN OTC DRUG LABEL 5 0363-0992 SPRAY 100 mg TOPICAL OTC monograph not final 12 sections
Well at Walgreens Mist Sheer Broad Spectrum Broad Spectrum SPF 30 HUMAN OTC DRUG LABEL 5 0363-0996 SPRAY 800 mg TOPICAL OTC monograph not final 13 sections
Hydrating SPF 50 HUMAN OTC DRUG LABEL 4 0363-1120 SPRAY 15 g TOPICAL OTC monograph not final 7 sections