dibrompropamidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3137 496-00-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dibrompropamidine
  • dibromopropamidine
  • dibrompropamidine hydrochloride
  • dibrompropamidine HCl
  • dibromopropamidine isethionate
  • dibromopropamidine isetionate
  • dibropropamidine isethionate
  • dibrompropamidine isetionate
  • dibrompropamidine isethionate
  • dibrompropamidine diisetionate
  • Molecular weight: 470.17
  • Formula: C17H18Br2N4O2
  • CLOGP: 2.96
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 4
  • TPSA: 118.20
  • ALOGS: -4.55
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D08AC01 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Biguanides and amidines
ATC S01AX14 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Other antiinfectives
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.38 Basic
pKa2 10.78 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Urokinase-type plasminogen activator Enzyme Ki 5.80 CHEMBL
Prothrombin Enzyme Ki 6.02 CHEMBL
Suppressor of tumorigenicity 14 protein Enzyme Ki 6.27 CHEMBL
Acrosin Enzyme Ki 5.77 CHEMBL

External reference:

IDSource
D07204 KEGG_DRUG
C0057799 UMLSCUI
CHEBI:135760 CHEBI
CHEMBL30044 ChEMBL_ID
DB13548 DRUGBANK_ID
C053597 MESH_SUPPLEMENTAL_RECORD_UI
450 INN_ID
614-87-9 SECONDARY_CAS_RN
269M3QL74S UNII
11974 PUBCHEM_CID
22862 RXNORM
005171 NDDF
005172 NDDF
396021007 SNOMEDCT_US
398837005 SNOMEDCT_US
422170002 SNOMEDCT_US

Pharmaceutical products:

None