ripazepam Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diazepam derivatives 2386 26308-28-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • CI-683
  • CI 683
  • ripazepam
  • pyrazapon
  • Molecular weight: 268.32
  • Formula: C15H16N4O
  • CLOGP: 1.31
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 59.28
  • ALOGS: -3.02
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.91 acidic
pKa2 4.68 Basic
pKa3 1.22 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
GABA-A receptor; anion channel Ion channel IC50 6.17 CHEMBL

External reference:

IDSource
D05733 KEGG_DRUG
C0109718 UMLSCUI
CHEBI:82529 CHEBI
CHEMBL159298 ChEMBL_ID
C009116 MESH_SUPPLEMENTAL_RECORD_UI
33474 PUBCHEM_CID
3751 INN_ID
92000WH9C9 UNII

Pharmaceutical products:

None