pyrvinium Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2335 3546-41-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pyrvinium pamoate
  • pyrvinium embonate
  • viprynium embonate
  • viprynium
  • pyrvinium
  • Molecular weight: 382.53
  • Formula: C26H28N3
  • CLOGP: 2.79
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 12.05
  • ALOGS: -6.16
  • ROTB: 4

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
0.35 g O

ADMET properties:

PropertyValueReference
BA (Bioavailability) 5 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

DateAgencyCompanyOrphan
None FDA PARKE DAVIS

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC P02CX01 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTHELMINTICS
ANTINEMATODAL AGENTS
Other antinematodals
MeSH PA D000871 Anthelmintics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000977 Antiparasitic Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.97 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0139597 UMLSCUI
D00489 KEGG_DRUG
310X6S84LW UNII
35163 RXNORM
007377 NDDF
707543009 SNOMEDCT_US
DB06816 DRUGBANK_ID
CHEBI:8688 CHEBI
CHEMBL1201303 ChEMBL_ID
D011774 MESH_DESCRIPTOR_UI
CHEMBL1908377 ChEMBL_ID
5281035 PUBCHEM_CID
C024631 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None