phloroglucinol Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2153 | 108-73-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A03AX12 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Other drugs for functional gastrointestinal disorders |
| MeSH PA | D007202 | Indicators and Reagents |
Drug Use (View source of the data)
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.35 | acidic |
| pKa2 | 10.35 | acidic |
| pKa3 | 12.36 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Beta-secretase 1 | Enzyme | IC50 | 4.44 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000166595 | NUI |
| C0031566 | UMLSCUI |
| D00152 | KEGG_DRUG |
| 8196 | RXNORM |
| 005931 | NDDF |
| 19341000122103 | SNOMEDCT_US |
| DHD7FFG6YS | UNII |
| 359 | PUBCHEM_CID |
| CHEBI:16204 | CHEBI |
| CHEMBL473159 | ChEMBL_ID |
| 13X | PDB_CHEM_ID |
| D010696 | MESH_DESCRIPTOR_UI |
| DB12944 | DRUGBANK_ID |
Pharmaceutical products:
None