calcium pantothenate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2055 79-83-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • calcium pantothenate
  • pantothenic acid
  • (+)-Pantothenic acid
  • D-Pantothenic acid
  • Vitamin B5
A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.
  • Molecular weight: 219.24
  • Formula: C9H17NO5
  • CLOGP: -1.49
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 4
  • TPSA: 106.86
  • ALOGS: -0.56
  • ROTB: 6

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 29, 1993 FDA HOSPIRA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Contraindicated product administered 129.79 11.27 3 42053 217645 63229321
Treatment failure 96.24 11.27 10 42046 199033 63247933
Synovitis 94.06 11.27 8 42048 186910 63260056
Systemic lupus erythematosus 88.05 11.27 16 42040 208902 63238064
Product use issue 86.50 11.27 20 42036 220500 63226466
Glossodynia 81.48 11.27 11 42045 178865 63268101
Product dose omission issue 80.66 11.27 338 41718 233975 63212991
Diarrhoea 78.73 11.27 770 41286 714596 62732370
Infusion related reaction 74.07 11.27 35 42021 245486 63201480
Maternal exposure during pregnancy 71.74 11.27 28 42028 220034 63226932
Pericarditis 70.92 11.27 4 42052 131575 63315391
Muscle spasms 70.81 11.27 246 41810 155904 63291062
Toxicity to various agents 69.00 11.27 39 42017 247211 63199755
Wound 61.67 11.27 16 42040 163247 63283719
Drug ineffective 60.21 11.27 426 41630 1044339 62402627
Drug intolerance 59.65 11.27 70 41986 308591 63138375
Device expulsion 58.20 11.27 92 41964 34830 63412136
Product use in unapproved indication 58.00 11.27 23 42033 179057 63267909
Unevaluable event 55.50 11.27 112 41944 51274 63395692
Off label use 55.07 11.27 245 41811 674217 62772749
Arthropathy 54.87 11.27 45 42011 234747 63212219
Fall 53.55 11.27 443 41613 391891 63055075
Full blood count decreased 48.20 11.27 72 41984 25952 63421014
Psoriasis 47.48 11.27 146 41910 86811 63360155
Helicobacter infection 46.57 11.27 4 42052 92781 63354185
Intentional product use issue 45.57 11.27 14 42042 127878 63319088
Device dislocation 44.61 11.27 69 41987 25636 63421330
Fatigue 43.32 11.27 826 41230 887202 62559764
Hepatic enzyme increased 41.11 11.27 44 42012 202284 63244682
Therapy cessation 41.09 11.27 73 41983 30384 63416582
Drug hypersensitivity 40.70 11.27 91 41965 310596 63136370
Flatulence 39.11 11.27 77 41979 34625 63412341
Lower respiratory tract infection 38.15 11.27 20 42036 132287 63314679
Dizziness 36.49 11.27 440 41616 429485 63017481
Deep vein thrombosis 36.20 11.27 130 41926 83670 63363296
Neuropathy peripheral 35.23 11.27 159 41897 113508 63333458
Asthenia 33.15 11.27 394 41662 383210 63063756
Therapeutic product effect incomplete 33.06 11.27 21 42035 125035 63321931
Folliculitis 32.78 11.27 4 42052 70313 63376653
Intentional overdose 32.72 11.27 5 42051 74147 63372819
Therapeutic product effect decreased 32.01 11.27 49 42007 193138 63253828
Nausea 31.95 11.27 765 41291 853706 62593260
Feeling abnormal 31.01 11.27 186 41870 148206 63298760
C-reactive protein increased 30.92 11.27 12 42044 94695 63352271
Memory impairment 30.21 11.27 143 41913 104115 63342851
General physical health deterioration 29.75 11.27 55 42001 201347 63245619
Hypoaesthesia 29.60 11.27 202 41854 168191 63278775
Constipation 29.55 11.27 252 41804 224691 63222275
Plasma cell myeloma 29.37 11.27 70 41986 35835 63411131
Discomfort 29.14 11.27 41 42015 167333 63279633
Joint swelling 28.49 11.27 116 41940 327550 63119416
Pneumonia 28.32 11.27 442 41614 456325 62990641
Drug interaction 26.92 11.27 71 41985 229060 63217906
Laboratory test abnormal 25.94 11.27 56 42000 26856 63420110
Headache 24.84 11.27 571 41485 632670 62814296
Depression 24.17 11.27 217 41839 196275 63250691
Haemoglobin decreased 24.08 11.27 172 41884 145313 63301653
Injection site pain 22.97 11.27 156 41900 129644 63317322
Dry skin 22.67 11.27 86 41970 56801 63390165
Exposure during pregnancy 21.64 11.27 44 42012 155503 63291463
Alopecia 21.60 11.27 133 41923 337403 63109563
Suicide attempt 21.10 11.27 7 42049 60911 63386055
Blister 20.48 11.27 34 42022 129780 63317186
Pelvic pain 20.32 11.27 34 42022 13485 63433481
Irritable bowel syndrome 20.23 11.27 15 42041 82397 63364569
Overdose 20.21 11.27 28 42028 115050 63331916
Paraesthesia 20.15 11.27 175 41881 156791 63290175
Hot flush 20.11 11.27 77 41979 51082 63395884
Dehydration 20.07 11.27 189 41867 173165 63273801
Eye swelling 19.96 11.27 47 42009 23871 63423095
Injection site haemorrhage 19.45 11.27 47 42009 24267 63422699
COVID-19 19.39 11.27 28 42028 113075 63333891
Liver injury 19.21 11.27 8 42048 60512 63386454
Hypersensitivity 18.89 11.27 115 41941 292570 63154396
Fluid retention 18.86 11.27 84 41972 59602 63387364
Back pain 18.84 11.27 262 41794 263883 63183083
Blepharospasm 17.95 11.27 21 42035 5975 63440991
Type 2 diabetes mellitus 17.90 11.27 10 42046 63858 63383108
Dyspnoea 17.81 11.27 568 41488 660745 62786221
Ill-defined disorder 17.48 11.27 17 42039 81738 63365228
Taste disorder 17.47 11.27 32 42024 13630 63433336
Injection site erythema 17.20 11.27 104 41952 83070 63363896
Influenza like illness 16.76 11.27 88 41968 66736 63380230
Pulmonary embolism 16.52 11.27 133 41923 116551 63330415
Condition aggravated 16.33 11.27 179 41877 402038 63044928
Nasal congestion 16.14 11.27 86 41970 65574 63381392
Urinary tract infection 15.93 11.27 255 41801 264429 63182537
Abdominal distension 15.86 11.27 105 41951 86510 63360456
Hip fracture 15.62 11.27 49 42007 29425 63417541
Infection 15.33 11.27 89 41967 229084 63217882
Pulmonary arterial hypertension 15.31 11.27 41 42015 22536 63424430
Rheumatoid arthritis 15.21 11.27 102 41954 253717 63193249
Skin discolouration 14.92 11.27 57 41999 37771 63409195
Vaginal haemorrhage 14.85 11.27 46 42010 27441 63419525
Hypervolaemia 14.84 11.27 47 42009 28366 63418600
Blood potassium decreased 14.70 11.27 61 41995 41965 63405001
Mucous stools 14.62 11.27 16 42040 4232 63442734
Impaired healing 14.26 11.27 29 42027 102513 63344453
Weight decreased 14.23 11.27 260 41796 276538 63170428
Injection site reaction 13.94 11.27 76 41980 58448 63388518
Swelling 13.51 11.27 117 41939 275261 63171705
Illness 13.29 11.27 8 42048 49051 63397915
Tremor 13.28 11.27 140 41916 132099 63314867
Depressed level of consciousness 13.16 11.27 13 42043 62065 63384901
Gastrooesophageal reflux disease 12.99 11.27 108 41948 95531 63351435
Administration site swelling 12.94 11.27 9 42047 1298 63445668
Intestinal dilatation 12.85 11.27 10 42046 1712 63445254
Dyspnoea exertional 12.85 11.27 76 41980 60226 63386740
Product complaint 12.74 11.27 27 42029 12782 63434184
Fibromyalgia 12.74 11.27 21 42035 80399 63366567
Plasma cell myeloma recurrent 12.66 11.27 13 42043 3200 63443766
Asthma 12.47 11.27 43 42013 127518 63319448
Balance disorder 12.37 11.27 97 41959 84325 63362641
Adverse event 12.31 11.27 16 42040 67543 63379423
Pulmonary hypertension 12.30 11.27 53 42003 37070 63409896
Body height decreased 12.13 11.27 23 42033 10055 63436911
White blood cell count decreased 12.02 11.27 143 41913 138961 63308005
Hospice care 11.99 11.27 20 42036 7912 63439054
Hypoxia 11.88 11.27 74 41982 59718 63387248
Chest discomfort 11.79 11.27 118 41938 109851 63337115
Prescribed overdose 11.70 11.27 4 42052 34149 63412817
Hepatic function abnormal 11.64 11.27 5 42051 37137 63409829
Multiple sclerosis relapse 11.58 11.27 63 41993 48415 63398551
Intentional product misuse 11.54 11.27 14 42042 60903 63386063
Chest pain 11.50 11.27 204 41852 215755 63231211
Atrial fibrillation 11.48 11.27 123 41933 116513 63330453
Abdominal discomfort 11.40 11.27 147 41909 320738 63126228
Dysgeusia 11.36 11.27 61 41995 46649 63400317

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 74.05 12.21 113 24442 419411 34512965
Fractional exhaled nitric oxide increased 63.10 12.21 25 24530 1057 34931319
Product use in unapproved indication 55.98 12.21 8 24547 117491 34814885
Fatigue 53.51 12.21 443 24112 370210 34562166
Plasma cell myeloma 49.19 12.21 98 24457 41939 34890437
Completed suicide 48.39 12.21 6 24549 98162 34834214
Sensation of foreign body 45.86 12.21 27 24528 2756 34929620
Product dose omission issue 44.38 12.21 184 24371 119527 34812849
Plantar fasciitis 44.26 12.21 24 24531 2092 34930284
Myoglobin blood increased 43.79 12.21 27 24528 2996 34929380
Drug interaction 41.53 12.21 59 24496 225887 34706489
Full blood count decreased 39.81 12.21 56 24499 18032 34914344
Cardiac disorder 37.28 12.21 89 24466 43037 34889339
Diarrhoea 35.65 12.21 424 24131 389488 34542888
Toxicity to various agents 35.17 12.21 54 24501 200308 34732068
Laboratory test abnormal 34.71 12.21 56 24499 20335 34912041
Brain natriuretic peptide increased 34.62 12.21 30 24525 5629 34926747
Fall 34.40 12.21 252 24303 202633 34729743
Muscle spasms 34.07 12.21 123 24432 74878 34857498
Asthenia 30.50 12.21 284 24271 244967 34687409
Secretion discharge 29.63 12.21 28 24527 5877 34926499
White blood cell count decreased 29.50 12.21 139 24416 95306 34837070
Adverse drug reaction 29.17 12.21 64 24491 29278 34903098
Exostosis 28.82 12.21 25 24530 4698 34927678
Dysphonia 26.72 12.21 54 24501 23329 34909047
Viral infection 25.48 12.21 45 24510 17578 34914798
Intentional product use issue 24.37 12.21 6 24549 59810 34872566
General physical health deterioration 22.07 12.21 35 24520 128234 34804142
Psoriasis 21.45 12.21 68 24487 38744 34893632
Dizziness 20.92 12.21 240 24315 218281 34714095
Intentional product misuse 19.73 12.21 4 24551 45607 34886769
Overdose 19.61 12.21 21 24534 91038 34841338
Multiple sclerosis relapse 19.59 12.21 34 24521 13099 34919277
Gait spastic 19.03 12.21 11 24544 1085 34931291
COVID-19 18.90 12.21 16 24539 77534 34854842
Influenza 18.88 12.21 77 24478 49589 34882787
Memory impairment 18.78 12.21 70 24485 43248 34889128
Neuropathy peripheral 18.66 12.21 111 24444 83152 34849224
Needle fatigue 18.45 12.21 10 24545 871 34931505
Rash 18.43 12.21 238 24317 222514 34709862
Pneumonia 17.77 12.21 355 24200 362272 34570104
Drug ineffective 17.66 12.21 221 24334 456530 34475846
Hepatic function abnormal 17.03 12.21 5 24550 44358 34888018
Relapsing-remitting multiple sclerosis 16.81 12.21 10 24545 1040 34931336
Treatment failure 16.62 12.21 6 24549 46691 34885685
Interstitial lung disease 16.49 12.21 13 24542 65269 34867107
Hypoaesthesia 15.80 12.21 85 24470 61359 34871017
Muscle spasticity 15.66 12.21 20 24535 5868 34926508
Dyspnoea exertional 15.59 12.21 66 24489 43213 34889163
Sinusitis 15.59 12.21 64 24491 41338 34891038
Thrombosis 15.22 12.21 73 24482 50385 34881991
Coma 14.44 12.21 7 24548 45671 34886705
Constipation 14.25 12.21 153 24402 136829 34795547
Multiple organ dysfunction syndrome 14.02 12.21 20 24535 76546 34855830
Peripheral swelling 13.46 12.21 96 24459 76445 34855931
Small intestinal obstruction 13.18 12.21 31 24524 14835 34917541
Balance disorder 13.12 12.21 60 24495 40594 34891782
Micturition urgency 12.61 12.21 19 24536 6506 34925870
Flatulence 12.50 12.21 38 24517 21160 34911216
Suicide attempt 12.36 12.21 6 24549 39110 34893266
Influenza like illness 12.26 12.21 45 24510 27589 34904787

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Completed suicide 132.69 10.55 7 52373 245760 79446248
Toxicity to various agents 100.45 10.55 78 52302 421462 79270546
Off label use 97.95 10.55 290 52090 906925 78785083
Product dose omission issue 91.52 10.55 363 52017 247174 79444834
Product use in unapproved indication 87.06 10.55 28 52352 250331 79441677
Treatment failure 85.68 10.55 7 52373 170479 79521529
Synovitis 73.55 10.55 7 52373 150727 79541281
Device expulsion 70.52 10.55 86 52294 25775 79666233
Fall 69.27 10.55 552 51828 487077 79204931
Drug interaction 68.73 10.55 104 52276 415079 79276929
Product use issue 66.93 10.55 27 52353 209795 79482213
Drug ineffective 62.12 10.55 436 51944 1080477 78611531
Diarrhoea 60.73 10.55 861 51519 879628 78812380
Plasma cell myeloma 58.10 10.55 116 52264 53143 79638865
Dizziness 56.70 10.55 561 51819 525880 79166128
Fatigue 55.89 10.55 888 51492 928839 78763169
Asthenia 53.99 10.55 543 51837 511146 79180862
Muscle spasms 52.71 10.55 241 52139 174489 79517519
Infusion related reaction 51.79 10.55 45 52335 230192 79461816
Intentional product use issue 51.13 10.55 18 52362 152094 79539914
Systemic lupus erythematosus 48.88 10.55 10 52370 121139 79570869
Intentional overdose 46.56 10.55 7 52373 105953 79586055
Therapy cessation 46.09 10.55 86 52294 37476 79654532
Drug intolerance 45.78 10.55 64 52316 264055 79427953
Deep vein thrombosis 43.55 10.55 176 52204 120743 79571265
General physical health deterioration 41.70 10.55 73 52307 275165 79416843
Full blood count decreased 41.49 10.55 68 52312 26751 79665257
Device dislocation 39.03 10.55 65 52315 25905 79666103
COVID-19 39.00 10.55 28 52352 157646 79534362
Intentional product misuse 38.09 10.55 8 52372 95157 79596851
Glossodynia 35.11 10.55 12 52368 103325 79588683
Drug hypersensitivity 34.70 10.55 92 52288 298824 79393184
Overdose 34.62 10.55 42 52338 184164 79507844
Therapeutic product effect incomplete 33.93 10.55 26 52354 141619 79550389
Maternal exposure during pregnancy 32.79 10.55 25 52355 136513 79555495
Pericarditis 32.27 10.55 14 52366 104222 79587786
Dehydration 31.41 10.55 274 52106 247913 79444095
Pneumonia 30.72 10.55 606 51774 659640 79032368
Lower respiratory tract infection 30.60 10.55 24 52356 129196 79562812
C-reactive protein increased 30.51 10.55 24 52356 129003 79563005
Unevaluable event 30.50 10.55 93 52287 55492 79636516
Duodenal ulcer perforation 29.96 10.55 4 52376 66207 79625801
Helicobacter infection 29.73 10.55 5 52375 69699 79622309
Haemoglobin decreased 29.57 10.55 248 52132 221871 79470137
Fluid retention 29.56 10.55 107 52273 69702 79622306
Hypoaesthesia 29.28 10.55 210 52170 179142 79512866
Arthropathy 28.64 10.55 45 52335 177066 79514942
Memory impairment 28.55 10.55 147 52233 111587 79580421
Nausea 27.15 10.55 821 51559 956375 78735633
Hepatic enzyme increased 27.13 10.55 49 52331 182561 79509447
Joint swelling 27.00 10.55 98 52282 288548 79403460
Dyspnoea 26.74 10.55 744 51636 856281 78835727
Multiple sclerosis relapse 26.61 10.55 79 52301 46454 79645554
Hypervolaemia 25.87 10.55 74 52306 42616 79649392
Depression 25.21 10.55 235 52145 216555 79475453
Feeling abnormal 25.18 10.55 185 52195 159014 79532994
Flatulence 24.87 10.55 73 52307 42651 79649357
Hospice care 24.44 10.55 32 52348 10292 79681716
Suicide attempt 24.34 10.55 12 52368 82920 79609088
Depressed level of consciousness 24.11 10.55 17 52363 96635 79595373
Injection site pain 23.54 10.55 156 52224 129682 79562326
Hepatic function abnormal 22.34 10.55 10 52370 73097 79618911
Needle fatigue 21.73 10.55 11 52369 891 79691117
Gait spastic 21.49 10.55 12 52368 1185 79690823
Mental status changes 21.40 10.55 94 52286 66865 79625143
Relapsing-remitting multiple sclerosis 21.37 10.55 13 52367 1506 79690502
Influenza like illness 20.93 10.55 98 52282 71609 79620399
Pelvic pain 20.79 10.55 34 52346 13347 79678661
Headache 20.75 10.55 569 51811 653203 79038805
Weight decreased 20.33 10.55 337 52043 354861 79337147
Hip fracture 20.29 10.55 55 52325 30706 79661302
Eye swelling 20.22 10.55 50 52330 26418 79665590
Viral infection 19.99 10.55 68 52312 42948 79649060
Eosinophilia 19.91 10.55 3 52377 45342 79646666
Folliculitis 19.57 10.55 6 52374 55374 79636634
Small intestinal obstruction 19.25 10.55 50 52330 27222 79664786
Dyspnoea exertional 18.51 10.55 109 52271 86964 79605044
Illness 18.43 10.55 4 52376 46507 79645501
Wound 18.32 10.55 30 52350 116149 79575859
Pulmonary arterial hypertension 18.00 10.55 50 52330 28316 79663692
Cholestasis 17.79 10.55 6 52374 52103 79639905
Psoriasis 17.06 10.55 109 52271 89478 79602530
Nasal congestion 17.04 10.55 97 52283 76455 79615553
Blood potassium decreased 16.97 10.55 68 52312 46444 79645564
Interstitial lung disease 16.91 10.55 30 52350 112570 79579438
Blepharospasm 16.83 10.55 20 52360 5831 79686177
Coma 16.82 10.55 25 52355 100624 79591384
Constipation 16.73 10.55 270 52110 282780 79409228
Injection site erythema 16.70 10.55 98 52282 78099 79613909
Complication associated with device 16.60 10.55 36 52344 17460 79674548
Injection site haemorrhage 16.58 10.55 48 52332 27822 79664186
Drug reaction with eosinophilia and systemic symptoms 16.42 10.55 11 52369 64233 79627775
Therapeutic response decreased 16.36 10.55 12 52368 66841 79625167
Multiple organ dysfunction syndrome 16.35 10.55 34 52346 120212 79571796
Cytomegalovirus infection 16.23 10.55 4 52376 42640 79649368
Dysgeusia 15.85 10.55 77 52303 57100 79634908
Pulmonary hypertension 15.75 10.55 68 52312 48012 79643996
White blood cell count decreased 15.73 10.55 191 52189 188097 79503911
Agranulocytosis 15.70 10.55 5 52375 45025 79646983
Micturition urgency 15.58 10.55 29 52351 12612 79679396
Irritable bowel syndrome 15.45 10.55 11 52369 62230 79629778
Abdominal pain 15.28 10.55 349 52031 389220 79302788
Haematocrit decreased 15.20 10.55 80 52300 61232 79630776
Hospitalisation 15.17 10.55 110 52270 94126 79597882
Neuropathy peripheral 14.85 10.55 150 52230 141155 79550853
Condition aggravated 14.72 10.55 236 52144 500888 79191120
Pulmonary embolism 14.72 10.55 175 52205 171479 79520529
Pleural effusion 14.69 10.55 153 52227 145109 79546899
Abdominal distension 14.55 10.55 131 52249 119519 79572489
Product complaint 14.46 10.55 29 52351 13320 79678688
Cytokine release syndrome 14.46 10.55 3 52377 35995 79656013
Taste disorder 14.38 10.55 32 52348 15791 79676217
Hypoxia 14.11 10.55 116 52264 103127 79588881
Back pain 14.02 10.55 279 52101 303901 79388107
Pollakiuria 13.97 10.55 55 52325 37262 79654746
Anxiety 13.92 10.55 235 52145 248277 79443731
Therapeutic product effect decreased 13.80 10.55 58 52322 163805 79528203
Cellulitis 13.57 10.55 120 52260 108940 79583068
Oedema peripheral 13.56 10.55 237 52143 252051 79439957
Cardiac failure congestive 13.48 10.55 148 52232 142254 79549754
Urinary tract infection 13.40 10.55 254 52126 274258 79417750
Vaginal haemorrhage 13.39 10.55 38 52342 21779 79670229
Rhabdomyolysis 13.32 10.55 30 52350 103101 79588907
Paraesthesia 13.09 10.55 175 52205 176148 79515860
Flushing 13.06 10.55 101 52279 88167 79603841
Transfusion 12.95 10.55 37 52343 21293 79670715
Migraine 12.88 10.55 100 52280 87393 79604615
Rectal fissure 12.84 10.55 8 52372 967 79691041
Fibromyalgia 12.80 10.55 14 52366 64326 79627682
Laboratory test abnormal 12.74 10.55 44 52336 28004 79664004
Drug resistance 12.55 10.55 6 52374 42207 79649801
Ill-defined disorder 12.39 10.55 15 52365 65860 79626148
Chest pain 12.36 10.55 257 52123 282047 79409961
Heavy menstrual bleeding 12.36 10.55 28 52352 13983 79678025
Tremor 12.29 10.55 168 52212 169915 79522093
Rotator cuff syndrome 12.25 10.55 28 52352 14067 79677941
Discomfort 12.17 10.55 42 52338 125575 79566433
Cardio-respiratory arrest 12.12 10.55 34 52346 108476 79583532
International normalised ratio increased 12.01 10.55 96 52284 84625 79607383
Gamma-glutamyltransferase increased 11.91 10.55 11 52369 54669 79637339
Cardiac disorder 11.90 10.55 79 52301 65678 79626330
Altered state of consciousness 11.89 10.55 7 52373 43815 79648193
Chills 11.88 10.55 159 52221 160075 79531933
Prescribed overdose 11.86 10.55 5 52375 37878 79654130
Neoplasm progression 11.73 10.55 10 52370 51672 79640336
Infective pulmonary exacerbation of cystic fibrosis 11.69 10.55 26 52354 12825 79679183
Infection 11.67 10.55 102 52278 241610 79450398
Diabetes mellitus 11.67 10.55 21 52359 78369 79613639
Laryngeal pain 11.55 10.55 17 52363 6097 79685911
Gait disturbance 11.53 10.55 196 52184 207310 79484698
Febrile neutropenia 11.36 10.55 97 52283 230902 79461106
Insomnia 11.33 10.55 225 52155 244945 79447063
Leukopenia 11.25 10.55 39 52341 116474 79575534
Thrombosis 11.23 10.55 94 52286 84006 79608002
Application site discolouration 11.16 10.55 7 52373 857 79691151
Exposure during pregnancy 11.07 10.55 32 52348 101100 79590908
Injection site nodule 11.01 10.55 13 52367 3767 79688241
Rheumatoid arthritis 10.96 10.55 86 52294 208384 79483624
Disease progression 10.93 10.55 176 52204 184186 79507822
Balance disorder 10.90 10.55 106 52274 98751 79593257
Blister 10.87 10.55 41 52339 119435 79572573
Renal impairment 10.86 10.55 60 52320 157723 79534285
Intestinal dilatation 10.85 10.55 11 52369 2689 79689319
Application site erythema 10.82 10.55 15 52365 5095 79686913
Dry skin 10.73 10.55 79 52301 67916 79624092
Neurotoxicity 10.66 10.55 4 52376 32514 79659494
Rash pruritic 10.61 10.55 82 52298 71547 79620461
Drug eruption 10.60 10.55 8 52372 43927 79648081
Intestinal mucosal hypertrophy 10.59 10.55 5 52375 348 79691660

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A11HA31 ALIMENTARY TRACT AND METABOLISM
VITAMINS
OTHER PLAIN VITAMIN PREPARATIONS
Other plain vitamin preparations
ATC D03AX04 DERMATOLOGICALS
PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS
CICATRIZANTS
Other cicatrizants
MeSH PA D018977 Micronutrients
MeSH PA D014803 Vitamin B Complex
MeSH PA D014815 Vitamins
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:74530 curare poisoning antidote
CHEBI has role CHEBI:85234 human blood serum metabolites
CHEBI has role CHEBI:176497 geroprotectors

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Ascorbic acid deficiency indication 76169001
Pantothenic acid deficiency indication 238128006
Methemoglobinemia off-label use 38959009 DOID:10783
Primary hyperoxaluria contraindication 17901006 DOID:2977
Kidney disease contraindication 90708001 DOID:557
Anemia due to enzyme deficiency contraindication 111577008
Hb SS disease contraindication 127040003 DOID:10923
Hemochromatosis contraindication 399187006 DOID:2352




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.62 acidic
pKa2 12.98 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
568ET80C3D UNII
4020312 VUID
N0000178898 NUI
D01082 KEGG_DRUG
4017627 VANDF
4017672 VANDF
4020312 VANDF
4021034 VANDF
4021902 VANDF
C0006710 UMLSCUI
CHEBI:31345 CHEBI
PAU PDB_CHEM_ID
CHEMBL1901349 ChEMBL_ID
443753 PUBCHEM_CID
CHEMBL1594 ChEMBL_ID
D010205 MESH_DESCRIPTOR_UI
1260 INN_ID
4668 IUPHAR_LIGAND_ID
DB01783 DRUGBANK_ID
1918 RXNORM
5685 MMSL
7440 MMSL
NOCODE MMSL
001056 NDDF
001057 NDDF
126225001 SNOMEDCT_US
66441000 SNOMEDCT_US
86431009 SNOMEDCT_US
137-08-6 SECONDARY_CAS_RN

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Strovite Forte Caplet HUMAN PRESCRIPTION DRUG LABEL 19 0642-0204 TABLET, COATED 25 mg ORAL UNAPPROVED DRUG OTHER 15 sections
Strovite One Caplets HUMAN PRESCRIPTION DRUG LABEL 20 0642-0207 TABLET 7.50 mg ORAL UNAPPROVED DRUG OTHER 14 sections
Strovite One Caplets HUMAN PRESCRIPTION DRUG LABEL 20 0642-0207 TABLET 7.50 mg ORAL UNAPPROVED DRUG OTHER 14 sections
Strovite One Caplets HUMAN PRESCRIPTION DRUG LABEL 20 0642-0207 TABLET 7.50 mg ORAL UNAPPROVED DRUG OTHER 14 sections
Strovite One Caplets HUMAN PRESCRIPTION DRUG LABEL 20 0642-0207 TABLET 7.50 mg ORAL UNAPPROVED DRUG OTHER 14 sections
BACMIN HUMAN PRESCRIPTION DRUG LABEL 19 0682-3001 TABLET, COATED 25 mg ORAL UNAPPROVED DRUG OTHER 10 sections
Dialyvite Supreme D HUMAN PRESCRIPTION DRUG LABEL 13 10542-009 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite Supreme D HUMAN PRESCRIPTION DRUG LABEL 13 10542-009 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite HUMAN PRESCRIPTION DRUG LABEL 9 10542-010 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite HUMAN PRESCRIPTION DRUG LABEL 9 10542-010 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite 5000 HUMAN PRESCRIPTION DRUG LABEL 12 10542-011 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite 5000 HUMAN PRESCRIPTION DRUG LABEL 12 10542-011 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite with Zinc HUMAN PRESCRIPTION DRUG LABEL 10 10542-012 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite with Zinc HUMAN PRESCRIPTION DRUG LABEL 10 10542-012 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite 3000 HUMAN PRESCRIPTION DRUG LABEL 12 10542-014 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Dialyvite 3000 HUMAN PRESCRIPTION DRUG LABEL 12 10542-014 TABLET, COATED 10 mg ORAL Unapproved drug other 7 sections
Se-Natal 19 HUMAN PRESCRIPTION DRUG LABEL 15 13925-116 TABLET 7 mg ORAL unapproved drug other 15 sections
Se-Natal 19 HUMAN PRESCRIPTION DRUG LABEL 15 13925-116 TABLET 7 mg ORAL unapproved drug other 15 sections
Se-Natal 19 Chewable HUMAN PRESCRIPTION DRUG LABEL 14 13925-117 TABLET, CHEWABLE 7 mg ORAL unapproved drug other 16 sections
Se-Tan PLUS HUMAN PRESCRIPTION DRUG LABEL 13 13925-118 CAPSULE, GELATIN COATED 10 mg ORAL unapproved drug other 19 sections
Se-Tan PLUS HUMAN PRESCRIPTION DRUG LABEL 13 13925-118 CAPSULE, GELATIN COATED 10 mg ORAL unapproved drug other 19 sections
Quflora FE Pediatric Drops HUMAN PRESCRIPTION DRUG LABEL 14 15370-102 LIQUID 1 mg ORAL UNAPPROVED DRUG OTHER 11 sections
Dialyvite HUMAN PRESCRIPTION DRUG LABEL 9 17856-0010 TABLET, COATED 10 mg ORAL Unapproved drug other 8 sections
Centratex HUMAN PRESCRIPTION DRUG LABEL 13 23359-100 CAPSULE 10 mg ORAL unapproved drug other 13 sections
PNV-Select HUMAN PRESCRIPTION DRUG LABEL 18 42192-320 TABLET, FILM COATED 6 mg ORAL unapproved drug other 10 sections
Multi Vitamin and Mineralvitamin HUMAN OTC DRUG LABEL 11 51220-2001 TABLET, CHEWABLE 1.50 mg ORAL unapproved drug other 16 sections
Concept OB HUMAN PRESCRIPTION DRUG LABEL 15 52747-620 CAPSULE 7 mg ORAL unapproved drug other 13 sections
Concept OB HUMAN PRESCRIPTION DRUG LABEL 15 52747-620 CAPSULE 7 mg ORAL unapproved drug other 13 sections
Concept DHA HUMAN PRESCRIPTION DRUG LABEL 15 52747-621 CAPSULE, LIQUID FILLED 5 mg ORAL unapproved drug other 7 sections
Concept DHA HUMAN PRESCRIPTION DRUG LABEL 15 52747-621 CAPSULE, LIQUID FILLED 5 mg ORAL unapproved drug other 7 sections