oxomemazine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2025 3689-50-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxomemazine
  • doxergan
  • dysedon
  • oxomemazin
selective for M1 muscarinic receptors
  • Molecular weight: 330.45
  • Formula: C18H22N2O2S
  • CLOGP: 2.52
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 40.62
  • ALOGS: -3.59
  • ROTB: 4

Drug dosage:

DoseUnitRoute
30 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Victim of chemical submission 89.57 77.54 11 221 252 50604640

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Victim of chemical submission 79.68 67.65 10 269 290 64498163

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R06AD08 RESPIRATORY SYSTEM
ANTIHISTAMINES FOR SYSTEMIC USE
ANTIHISTAMINES FOR SYSTEMIC USE
Phenothiazine derivatives

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.92 Basic
pKa2 3.55 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07401 KEGG_DRUG
C0768401 UMLSCUI
CHEBI:135408 CHEBI
CHEMBL2104734 ChEMBL_ID
DB13820 DRUGBANK_ID
C119593 MESH_SUPPLEMENTAL_RECORD_UI
19396 PUBCHEM_CID
1412 INN_ID
305MB38V1C UNII
005705 NDDF

Pharmaceutical products:

None