Results: 1

dupilumab Dupilumab is a human monoclonal IgG4 antibody that inhibits interleukin-4 (IL-4) and interleukin-13 (IL-13) signaling by specifically binding to the IL-4Rα subunit shared by the IL-4 and IL-13 receptor complexes. Dupilumab inhibits IL-4 signaling via the Type I receptor and both IL-4 and IL-13 signaling through the Type II receptor. Blocking IL-4Rα with dupilumab inhibits IL-4 and IL-13 cytokine-induced responses, including the release of proinflammatory cytokines, chemokines and IgE.

Drugs in the News


Dexamethasone Baloxavir ChloroquinePhosphate Favipiravir Lopinavir Atazanavir Darunavir Nelfinavir Hydroxychloroquine Oseltamivir Remdesivir Umifenovir Azithromycin


DrugCentral Search Overview