Solute carrier organic anion transporter family member 1B1

Description:

Description
  • Accession: Q9Y6L6
  • Swissprot: SO1B1_HUMAN
  • Organism: Homo sapiens
  • Gene: SLCO1B1
  • Target class: Transporter

Drug Relations:

ciclosporin
A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed). Bioactivity details MOA
lapatinib
an EGFR-ErbB-2 inhibitor Bioactivity details MOA
repaglinide
Bioactivity details MOA
rifampicin
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160) Bioactivity details MOA
rifamycin
Bioactivity details MOA