Interleukin-1 receptor accessory protein


  • Accession: Q9NPH3
  • Swissprot: IL1AP_HUMAN
  • Organism: Homo sapiens
  • Gene: IL1RAP
  • Target class: Membrane receptor

Drug Relations:

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA. Bioactivity details MOA