Voltage-dependent T-type calcium channel subunit alpha-1H


  • Accession: Q9EQ60
  • Swissprot: CAC1H_RAT
  • Organism: Rattus norvegicus
  • Gene: Cacna1h
  • Target class: Ion channel

Drug Relations:

A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403) Bioactivity details MOA