Melatonin receptor type 1B


  • Accession: P51050
  • Swissprot: MTR1B_CHICK
  • Organism: Gallus gallus
  • Target class: GPCR

Drug Relations:

an antidepressant, it works by stimulating the MT1 and MT2 receptors, which are normally activated by melatonin, and also by blocking the 5-HT2C receptors, which are normally activated by the neurotransmitter 5-hydroxytryptamine Bioactivity details MOA
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. Bioactivity details MOA