DNA (cytosine-5)-methyltransferase 1

Description:

Description
  • Accession: P26358
  • Swissprot: DNMT1_HUMAN
  • Organism: Homo sapiens
  • Gene: DNMT1
  • Target class: Enzyme

Drug Relations:

azacitidine
A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent. Bioactivity details MOA
decitabine
Bioactivity details MOA
hydralazine
A direct-acting vasodilator that is used as an antihypertensive agent. Bioactivity details MOA
procainamide
A class Ia antiarrhythmic drug that is structurally-related to PROCAINE. Bioactivity details MOA