Cannabinoid receptor 1

Description:

Description
  • Accession: P20272
  • Swissprot: CNR1_RAT
  • Organism: Rattus norvegicus
  • Gene: Cnr1
  • Target class: GPCR

Drug Relations:

dronabinol
A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. Bioactivity details MOA
nabilone
cannabinol deriv; RN given refers to cpd without isomeric designation; structure Bioactivity details MOA
rimonabant
A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY. Bioactivity details MOA