Neuronal acetylcholine receptor subunit beta-2

Description:

Description
  • Accession: P12390
  • Swissprot: ACHB2_RAT
  • Organism: Rattus norvegicus
  • Gene: Chrnb2
  • Target class: Ion channel

Drug Relations:

acetylcholine
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. Bioactivity details MOA
carbachol
A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS. Bioactivity details MOA
choline
A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. Bioactivity details MOA
decamethonium
Bioactivity details MOA
hexamethonium
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool. Bioactivity details MOA
nicotine
Devices or delivery systems used to aid in ending a TOBACCO habit. Bioactivity details MOA
tubocurarine
A neuromuscular blocker and active ingredient in CURARE; plant based alkaloid of Menispermaceae. Bioactivity details MOA
varenicline
A benzazepine derivative that functions as an ALPHA4-BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION. Bioactivity details MOA