Glutathione S-transferase P


  • Accession: P09211
  • Swissprot: GSTP1_HUMAN
  • Organism: Homo sapiens
  • Gene: GSTP1
  • Target class: Enzyme

Drug Relations:

A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine. Bioactivity details MOA
ethacrynic acid
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic. Bioactivity details MOA