Neprilysin

Description:

Description
  • Accession: P08473
  • Swissprot: NEP_HUMAN
  • Organism: Homo sapiens
  • Gene: MME
  • Target class: Enzyme

Drug Relations:

racecadotril
A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms. Bioactivity details MOA
sacubitril
inhibits neprilysin (neutral endopeptidase; NEP) via LBQ657, the active metabolite and leads to increased levels of peptides that are degraded by neprilysin such as natriuretic peptides Bioactivity details MOA
omapatrilat
Bioactivity details MOA