72 kDa type IV collagenase

Description:

Description
  • Accession: P08253
  • Swissprot: MMP2_HUMAN
  • Organism: Homo sapiens
  • Gene: MMP2
  • Target class: Enzyme

Drug Relations:

aclarubicin
An anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity. Bioactivity details MOA
cefotetan
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms. Bioactivity details MOA
cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS. Bioactivity details MOA
chlorhexidine
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. Bioactivity details MOA
daunorubicin
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS. Bioactivity details MOA
doxorubicin
Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN. Bioactivity details MOA
doxycycline
A synthetic tetracycline derivative with similar antimicrobial activity. Bioactivity details MOA
oxyquinoline
An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics. Bioactivity details MOA
quercetin
A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin. Bioactivity details MOA
sulindac
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects. Bioactivity details MOA
tiludronic acid
a bone resorption inhibitor; an antihypercalcemic agent; used in the tratment of Paget's disease; used in the treatment and prevention of osteoporosis; structure given in first source Bioactivity details MOA
ubenimex
growth inhibitor; RN given refers to ((L-Leu)-(S-(R*,S*)))-isomer; structure Bioactivity details MOA
zoledronic acid
a potent inhibitor of bone resorption; structure given in first source Bioactivity details MOA