Proto-oncogene tyrosine-protein kinase Src

Description:

Description
  • Accession: P00523
  • Swissprot: SRC_CHICK
  • Organism: Gallus gallus
  • Gene: SRC
  • Target class: Kinase

Drug Relations:

dasatinib
A pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB. Bioactivity details MOA
imatinib
A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors. Bioactivity details MOA
ponatinib
a pan-Bcr-Abl protein kinase Inhibitor Bioactivity details MOA
sunitinib
inhibits VEGF-R2 and PDGF-Rbeta tyrosine kinase; has antineoplastic activity Bioactivity details MOA