High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

Description:

Description
  • Accession: O95263
  • Swissprot: PDE8B_HUMAN
  • Organism: Homo sapiens
  • Gene: PDE8B
  • Target class: Enzyme

Drug Relations:

dipyridamole
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752) Bioactivity details MOA
flavoxate
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. Bioactivity details MOA