Nuclear receptor subfamily 1 group I member 2


  • Accession: O54915
  • Swissprot: NR1I2_MOUSE
  • Organism: Mus musculus
  • Gene: Nr1i2
  • Target class: Nuclear hormone receptor

Drug Relations:

An anti-inflammatory 9-fluoro-glucocorticoid. Bioactivity details MOA
A complex structure that includes isoquinolines joined by a cyclic ester; it is a DNA-binding agent and guanine N2 alkylator derived from the marine tunicate, Ecteinascidia turbinata. Trabectedin is used for the treatment of advanced soft-tissue SARCOMA, after failure of ANTHRACYCLINES or IFOSFAMIDE drug therapy. Bioactivity details MOA