dopexamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| dopaminergic agents dopamine derivatives used as cardiac stimulant/antihypertensives/diuretics | 948 | 86197-47-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.50 | g | P |
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Jan. 1, 1989 | YEAR INTRODUCED |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | C01CA14 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES Adrenergic and dopaminergic agents |
| MeSH PA | D018663 | Adrenergic Agents |
| MeSH PA | D000322 | Adrenergic Agonists |
| MeSH PA | D000318 | Adrenergic beta-Agonists |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D015259 | Dopamine Agents |
| MeSH PA | D018491 | Dopamine Agonists |
| MeSH PA | D018377 | Neurotransmitter Agents |
| MeSH PA | D014665 | Vasodilator Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 10.35 | acidic |
| pKa2 | 13.49 | acidic |
| pKa3 | 9.93 | Basic |
| pKa4 | 9.24 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Beta-2 adrenergic receptor | GPCR | WOMBAT-PK | |||||||
| D(1A) dopamine receptor | GPCR | WOMBAT-PK |
External reference:
| ID | Source |
|---|---|
| D03891 | KEGG_DRUG |
| C0058702 | UMLSCUI |
| CHEMBL77622 | ChEMBL_ID |
| DB12313 | DRUGBANK_ID |
| C046318 | MESH_SUPPLEMENTAL_RECORD_UI |
| 55483 | PUBCHEM_CID |
| 5455 | INN_ID |
| 398E7Z7JB5 | UNII |
| 23638 | RXNORM |
| 003701 | NDDF |
| 349922000 | SNOMEDCT_US |
| 419490003 | SNOMEDCT_US |
Pharmaceutical products:
None