adinazolam Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
diazepam derivatives 93 37115-32-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • adinazolam
  • adinazolam mesylate
  • adinazolam mesilate
  • deracyn
  • Molecular weight: 351.84
  • Formula: C19H18ClN5
  • CLOGP: 2.12
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 46.31
  • ALOGS: -3.72
  • ROTB: 3

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

SourceCodeDescription
ATC N05BA07 NERVOUS SYSTEM
PSYCHOLEPTICS
ANXIOLYTICS
Benzodiazepine derivatives
MeSH PA D000928 Antidepressive Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D011619 Psychotropic Drugs
CHEBI has role CHEBI:35469 antidepressant
CHEBI has role CHEBI:35717 sedative
CHEBI has role CHEBI:35474 anxiolytic drug
CHEBI has role CHEBI:35623 anticonvulsant

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.71 Basic
pKa2 5.26 Basic
pKa3 3.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
GABA-A receptor Ion channel POSITIVE ALLOSTERIC MODULATOR SCIENTIFIC LITERATURE KEGG DRUG
Translocator protein Transporter IC50 7.10 WOMBAT-PK

External reference:

IDSource
D02770 KEGG_DRUG
CHEMBL328250 ChEMBL_ID
C074080 MESH_SUPPLEMENTAL_RECORD_UI
DB00546 DRUGBANK_ID
KN08449444 UNII
4996 INN_ID
57938-82-6 SECONDARY_CAS_RN
CHEBI:251412 CHEBI
C039668 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2106672 ChEMBL_ID
37632 PUBCHEM_CID

Pharmaceutical products:

None