DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
dioxyline 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
911
147-27-3
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
dioxyline phosphate
dimoxyline
dioxyline
paveril
Molecular weight: 367.45
Formula: C22H25NO4
CLOGP: 4.61
LIPINSKI: 0
HAC: 5
HDO: 0
TPSA: 49.81
ALOGS: -4.65
ROTB: 7
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
6.0
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Methionine aminopeptidase 2
Enzyme
P50579
MAP2_HUMAN
IC50
4.46
CHEMBL
Methionine aminopeptidase 1
Enzyme
P53582
MAP11_HUMAN
IC50
4.37
CHEMBL
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External reference:
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entries
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ID
Source
000695
NDDF
208
INN_ID
21877
PUBCHEM_CID
28464005
SNOMEDCT_US
412174005
SNOMEDCT_US
46X4C9TILS
UNII
C004856
MESH_SUPPLEMENTAL_RECORD_UI
C0602100
UMLSCUI
CHEBI:135548
CHEBI
CHEMBL1170610
ChEMBL_ID
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Pharmaceutical products:
None
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dioxyline