diloxanide furoate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiparasitics, salicylanilides and analogues 896 3736-81-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • diloxanide furoate
  • amebiazol
  • dichlofurazol
  • diclofurazol
  • diloxanid furoate
  • entamide furoate
  • furamide
  • furentomin
  • Molecular weight: 328.15
  • Formula: C14H11Cl2NO4
  • CLOGP: 3.09
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 59.75
  • ALOGS: -3.93
  • ROTB: 5

Drug dosage:

None

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 2 Benet LZ, Broccatelli F, Oprea TI
EoM (Fraction excreted unchanged in urine) 1 % Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose) 65.30 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000563 Amebicides
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000981 Antiprotozoal Agents
CHEBI has role CHEBI:50266 Prodrugs
CHEBI has role CHEBI:171664 antiamoebic drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Amebic infection indication 111910009 DOID:9181




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02480 KEGG_DRUG
23203 RXNORM
C0058181 UMLSCUI
CHEBI:4601 CHEBI
CHEMBL1334860 ChEMBL_ID
DB14638 DRUGBANK_ID
C004932 MESH_SUPPLEMENTAL_RECORD_UI
19529 PUBCHEM_CID
YP4N72IW34 UNII
002955 NDDF
396029009 SNOMEDCT_US
579-38-4 SECONDARY_CAS_RN

Pharmaceutical products:

None