adenine indications/contra

Stem definitionDrug idCAS RN
89 73-24-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • adenine
  • 9H-Purin-6-amine
  • vitamin B4
  • adeninimine
A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
  • Molecular weight: 135.13
  • Formula: C5H5N5
  • CLOGP: -0.15
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 80.48
  • ALOGS: -1.07
  • ROTB: 0

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.64 acidic
pKa2 5.16 Basic
pKa3 0.18 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Phosphatidylinositol 4-kinase, PI4K Kinase Ki 4.07 CHEMBL
Xanthine dehydrogenase/oxidase Enzyme IC50 4.96 CHEMBL

External reference:

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IDSource
CHEBI:16708 CHEBI
DB00173 DRUGBANK_ID
4788 IUPHAR_LIGAND_ID
4018883 VUID
N0000147177 NUI
C0001407 UMLSCUI
D00034 KEGG_DRUG
4018883 VANDF
70203000 SNOMEDCT_US
N0000007309 NDFRT
N0000147177 NDFRT
005667 NDDF
290 RXNORM
CHEMBL226345 ChEMBL_ID
CHEMBL1797130 ChEMBL_ID
JAC85A2161 UNII
D000225 MESH_DESCRIPTOR_UI
190 PUBCHEM_CID

Pharmaceutical products:

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ProductCategoryIngredientsNDCFormQuantityRoute MarketingLabel
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6301 SOLUTION 19.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6305 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6307 SOLUTION 19.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6308 SOLUTION 19.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6309 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6312 SOLUTION 19.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6316 SOLUTION 19.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6317 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6319 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6320 SOLUTION 19.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6321 SOLUTION 9.60 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6322 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6326 SOLUTION 19.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6327 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6328 SOLUTION 13.50 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6329 SOLUTION 13.50 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6330 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6331 SOLUTION 13.50 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6332 SOLUTION 13.50 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6336 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6343 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
CPDA-1 HUMAN PRESCRIPTION DRUG LABEL 5 0942-6344 SOLUTION 17.30 mg INTRAVENOUS NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6430 KIT 27 mg None NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6431 KIT 30 mg None NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6436 KIT 27 mg None NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6439 KIT 30 mg None NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6444 KIT 30 mg None NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6445 KIT 30 mg None NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6449 KIT 27 mg None NDA 2 sections
ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) HUMAN PRESCRIPTION DRUG LABEL 8 0942-6453 KIT 30 mg None NDA 2 sections