difebarbamate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
hypnotics, barbituric acid derivatives 876 15687-09-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • difebarbamate
  • Molecular weight: 578.66
  • Formula: C28H42N4O9
  • CLOGP: 4.43
  • LIPINSKI: 2
  • HAC: 13
  • HDO: 2
  • TPSA: 180.79
  • ALOGS: -4.84
  • ROTB: 20

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PRKDC,TEK 21
kinase-selectivity-class AXL,GRK2,TEK 3
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
23020 RXNORM
C0057977 UMLSCUI
CHEBI:135839 CHEBI
CHEMBL2105563 ChEMBL_ID
C007383 MESH_SUPPLEMENTAL_RECORD_UI
1240 INN_ID
7EE4K616KK UNII
71880 PUBCHEM_CID
005324 NDDF

Pharmaceutical products:

None