adamexine indications/contra

Stem definitionDrug idCAS RN
mucolytic, bromhexine derivatives 86 54785-02-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • broncostyl
  • adamexina
  • adamexine
mucolytic molecule in which cyclohexyl ring of bromhexine is replaced with adamantane
  • Molecular weight: 470.25
  • Formula: C20H26Br2N2O
  • CLOGP: 4.20
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 32.34
  • ALOGS: -6.22
  • ROTB: 4

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.02 acidic
pKa2 7.58 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
6LPU49W75V UNII
4002 INN_ID
64387 PUBCHEM_CID
C025184 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2105546 ChEMBL_ID
CHEBI:135761 CHEBI

Pharmaceutical products:

None