mitobronitol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antineoplastics, nucleotoxic agents 858 488-41-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dibromomannitol
  • dibromannit
  • dibromannitol
  • mielobromol
  • myelobromol
  • mitobronitol
Brominated analog of MANNITOL which is an antineoplastic agent appearing to act as an alkylating agent.
  • Molecular weight: 307.97
  • Formula: C6H12Br2O4
  • CLOGP: -0.38
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 4
  • TPSA: 80.92
  • ALOGS: -0.89
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01AX01 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
ALKYLATING AGENTS
Other alkylating agents
MeSH PA D000477 Alkylating Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018906 Antineoplastic Agents, Alkylating
MeSH PA D009676 Noxae

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.56 acidic
pKa2 13.21 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000168408 NUI
D02020 KEGG_DRUG
203009 RXNORM
CHEBI:34853 CHEBI
CHEMBL447629 ChEMBL_ID
2454 INN_ID
DB13543 DRUGBANK_ID
5UP30YED7N UNII
004464 NDDF
29089004 SNOMEDCT_US
387156002 SNOMEDCT_US
C0026236 UMLSCUI
D008927 MESH_DESCRIPTOR_UI
656655 PUBCHEM_CID

Pharmaceutical products:

None