Stem definition | Drug id | CAS RN |
---|---|---|
846 | 51-49-0 |
Dose | Unit | Route |
---|---|---|
4 | mg | O |
None
Date | Agency | Company | Orphan |
---|---|---|---|
April 14, 1967 | FDA | ABBVIE |
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | C10AX01 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, PLAIN Other lipid modifying agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Hyperlipidemia | indication | 55822004 | DOID:1168 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 2.08 | acidic |
pKa2 | 6.63 | acidic |
pKa3 | 8.6 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Thyroid hormone receptor | Nuclear hormone receptor | AGONIST | CHEMBL | CHEMBL | |||||
Thyroid hormone receptor beta | Transcription factor | IC50 | 7.46 | CHEMBL | |||||
Glutamate NMDA receptor | Ion channel | IC50 | 6.48 | CHEMBL |
ID | Source |
---|---|
4022400 | VUID |
N0000020406 | NUI |
D03750 | KEGG_DRUG |
227544 | RXNORM |
4018501 | VANDF |
4022400 | VANDF |
C0011824 | UMLSCUI |
CHEBI:30659 | CHEBI |
CHEMBL559 | ChEMBL_ID |
CHEMBL3545058 | ChEMBL_ID |
D003918 | MESH_DESCRIPTOR_UI |
DB00509 | DRUGBANK_ID |
6951 | IUPHAR_LIGAND_ID |
7054-08-2 | SECONDARY_CAS_RN |
4W9K63FION | UNII |
8730 | PUBCHEM_CID |
308 | MMSL |
4569 | MMSL |
d00747 | MMSL |
002055 | NDDF |
004779 | NDDF |
59170000 | SNOMEDCT_US |
61899008 | SNOMEDCT_US |
847003 | SNOMEDCT_US |
CHEMBL1200777 | ChEMBL_ID |
None