rosoxacin indications/contra

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 83 40034-42-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acrosoxacin
  • eradacil
  • rosoxacin
  • eradacin
  • Molecular weight: 294.31
  • Formula: C17H14N2O3
  • CLOGP: 2.17
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 70.50
  • ALOGS: -3.46
  • ROTB: 3

Drug dosage:

DoseUnitRoute
0.30 g O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC J01MB01 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Other quinolones
CHEBI has role CHEBI:36047 antibacterial drug
CHEBI has role CHEBI:35441 antiinfective agent
MeSH PA D000890 Anti-Infective Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.11 acidic
pKa2 5.45 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0073591 UMLSCUI
D02305 KEGG_DRUG
3Y1OT3J4NW UNII
3903 INN_ID
DB00817 DRUGBANK_ID
CHEMBL291157 ChEMBL_ID
287180 PUBCHEM_CID
387556005 SNOMEDCT_US
35797 RXNORM
96093003 SNOMEDCT_US
004035 NDDF
CHEBI:131715 CHEBI
C021083 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None