dexamethasone indications/contra

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 824 50-02-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dexamethasone
  • dexasone
  • dexmethsone
An anti-inflammatory 9-fluoro-glucocorticoid.
  • Molecular weight: 392.47
  • Formula: C22H29FO5
  • CLOGP: 1.79
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 94.83
  • ALOGS: -3.89
  • ROTB: 2

Drug dosage:

DoseUnitRoute
1.50 mg O
1.50 mg P

Approvals:

DateAgencyCompanyOrphan
Oct. 30, 1958 FDA

FDA Adverse Event Reporting System

scroll-->
MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pneumonia 3400.64 24.52 1635 24699 68508 3291017
Plasma cell myeloma 3147.85 24.52 1008 25326 13592 3345933
Thrombocytopenia 3001.49 24.52 1223 25111 34045 3325480
Neutropenia 2899.49 24.52 1175 25159 32211 3327314
Febrile neutropenia 2670.03 24.52 951 25383 18024 3341501
Neuropathy peripheral 2308.90 24.52 828 25506 15979 3343546
Sepsis 2239.27 24.52 970 25364 31403 3328122
Pyrexia 1929.95 24.52 1183 25151 79932 3279593
Anaemia 1750.49 24.52 966 25368 53367 3306158
Diarrhoea 1723.17 24.52 1211 25123 103137 3256388
Fatigue 1423.64 24.52 1092 25242 106148 3253377
Hyperglycaemia 1259.49 24.52 446 25888 8222 3351303
Septic shock 1252.19 24.52 486 25848 11698 3347827
Disease progression 1213.55 24.52 637 25697 31622 3327903
Infection 1211.21 24.52 589 25745 24813 3334712
Deep vein thrombosis 1132.12 24.52 533 25801 20856 3338669
Pancytopenia 1123.95 24.52 510 25824 18310 3341215
Acute kidney injury 1083.96 24.52 688 25646 48995 3310530
Constipation 1033.57 24.52 564 25770 30248 3329277
Pulmonary embolism 1009.39 24.52 537 25797 27351 3332174
Death 963.10 24.52 1022 25312 151302 3208223
Asthenia 914.61 24.52 690 25644 64975 3294550
Vomiting 889.76 24.52 772 25562 88759 3270766
Platelet count decreased 869.04 24.52 484 25850 26984 3332541
Off label use 854.49 24.52 613 25721 53364 3306161
Hypotension 845.46 24.52 589 25745 48925 3310600
Dyspnoea 839.17 24.52 794 25540 102140 3257385
Nausea 827.16 24.52 875 25459 128770 3230755
Renal failure 792.47 24.52 486 25848 32454 3327071
Posterior reversible encephalopathy syndrome 778.33 24.52 244 26090 3010 3356515

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC A01AC02 ALIMENTARY TRACT AND METABOLISM
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
Corticosteroids for local oral treatment
ATC C05AA09 CARDIOVASCULAR SYSTEM
VASOPROTECTIVES
AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Corticosteroids
ATC D07AB19 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, PLAIN
Corticosteroids, moderately potent (group II)
ATC D07XB05 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, OTHER COMBINATIONS
Corticosteroids, moderately potent, other combinations
ATC D10AA03 DERMATOLOGICALS
ANTI-ACNE PREPARATIONS
ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Corticosteroids, combinations for treatment of acne
ATC H02AB02 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
CORTICOSTEROIDS FOR SYSTEMIC USE
CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Glucocorticoids
ATC R01AD03 RESPIRATORY SYSTEM
NASAL PREPARATIONS
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
Corticosteroids
ATC S01BA01 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS
Corticosteroids, plain
ATC S01CB01 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids/antiinfectives/mydriatics in combination
ATC S02BA06 SENSORY ORGANS
OTOLOGICALS
CORTICOSTEROIDS
Corticosteroids
ATC S03BA01 SENSORY ORGANS
OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
CORTICOSTEROIDS
Corticosteroids
ATC D07CB04 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
Corticosteroids, moderately potent, combinations with antibiotics
ATC R01AD53 RESPIRATORY SYSTEM
NASAL PREPARATIONS
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
Corticosteroids
ATC S01CA01 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
ATC S02CA06 SENSORY ORGANS
OTOLOGICALS
CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
ATC S03CA01 SENSORY ORGANS
OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
FDA EPC N0000175576 Corticosteroid
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
MeSH PA D000305 Adrenal Cortex Hormones
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000932 Antiemetics
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018931 Antineoplastic Agents, Hormonal
MeSH PA D001337 Autonomic Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
MeSH PA D006730 Hormones, Hormone Substitutes, and Hormone Antagonists
MeSH PA D018373 Peripheral Nervous System Agents
CHEBI has role CHEBI:50919 antiemetic
CHEBI has role CHEBI:37962 adrenergic agent
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:35705 immunosuppressive agent
CHEBI has role CHEBI:35472 anti-inflammatory drug

Drug Use (View source of the data)

scroll-->
DiseaseRelationSNOMED_IDDOID
Disorder of musculoskeletal system indication 928000 DOID:17
Cerebral edema indication 2032001 DOID:4724
Otitis externa indication 3135009 DOID:9463
Keratitis indication 5888003 DOID:4677
Berylliosis indication 8247009 DOID:10322
Psoriasis indication 9014002 DOID:8893
Ankylosing spondylitis indication 9631008 DOID:7147
Cyclitis indication 17657000
Rheumatic heart disease indication 23685000
Atopic dermatitis indication 24079001 DOID:3310
Inflammatory bowel disease indication 24526004 DOID:0050589
Multiple sclerosis indication 24700007 DOID:2377
Severe adrenal insufficiency indication 24867002
Sarcoidosis indication 31541009 DOID:13404
Idiopathic thrombocytopenic purpura indication 32273002 DOID:8924
Psoriasis with arthropathy indication 33339001 DOID:9008
Keloid scar indication 33659008
Crohn's disease indication 34000006
Erythema multiforme indication 36715001
Contact dermatitis indication 40275004 DOID:2773
Angioedema indication 41291007 DOID:1558
Punctate keratitis indication 42513006 DOID:12197
Miliary tuberculosis indication 47604008 DOID:9861
Humoral hypercalcemia of malignancy indication 47709007
Articular gout indication 48440001 DOID:13189
Seborrheic dermatitis indication 50563003 DOID:8741
Edema of larynx indication 51599000
Nephrotic syndrome indication 52254009 DOID:1184
Lichen simplex chronicus indication 53891004
Systemic lupus erythematosus indication 55464009 DOID:9074
Allergic rhinitis indication 61582004
Löffler's syndrome indication 64936001 DOID:9503
Iritis indication 65074000 DOID:1406
Pemphigus indication 65172003 DOID:9182
Granuloma annulare indication 65508009 DOID:3777
Tenosynovitis indication 67801009 DOID:970
Blepharoconjunctivitis indication 68659002 DOID:2456
Rheumatoid arthritis indication 69896004 DOID:7148
Transfusion reaction due to serum protein reaction indication 72284000
Epicondylitis indication 73583000 DOID:14087
Acquired thrombocytopenia indication 74576004 DOID:11126
Perforation of cornea indication 74895004
Iridocyclitis indication 77971008 DOID:1407
Thyroiditis indication 82119001 DOID:7166
Bursitis indication 84017003 DOID:2965
Corneal abrasion indication 85848002
Infection by larvae of Trichinella spiralis indication 88264003 DOID:9784
Congenital hypoplastic anemia indication 88854002 DOID:1342
Pruritus ani indication 90446007
Corneal ulcer indication 91514001 DOID:8463
Acute lymphoid leukemia indication 91857003 DOID:9952
Disorder of skin indication 95320005 DOID:37
Diffuse non-Hodgkin's lymphoma, large cell indication 109969005
Multiple myeloma indication 109989006 DOID:9538
Dermatitis herpetiformis indication 111196000 DOID:8505
Hodgkin's disease indication 118599009 DOID:8651
Non-Hodgkin's lymphoma indication 118601006 DOID:8675
Burkitt's lymphoma indication 118617000 DOID:8584
Mycosis fungoides indication 118618005 DOID:8691
Uveitis indication 128473001 DOID:13141
Asthma indication 195967001 DOID:2841
Discoid lupus erythematosus indication 200938002
Plaque psoriasis indication 200965009
Transplanted organ rejection indication 213148006
Central retinal vein occlusion with macular edema indication 232039004
Branch retinal vein occlusion with macular edema indication 232048009
Malignant otitis externa due to Pseudomonas aeruginosa indication 232230009
Scalp psoriasis indication 238608008
Punctate keratopathy indication 246936005
Adrenogenital disorder indication 267395000 DOID:0050811
Pruritus of genital organs indication 267802000
Eruption of skin indication 271807003 DOID:0050486
Exacerbation of asthma indication 281239006
Follicular non-Hodgkin's lymphoma indication 308121000
Infective otitis media indication 312218008
Infective blepharitis indication 312219000
Bacterial keratitis indication 314557000
Disorder of eye indication 371405004 DOID:5614
Primary adrenocortical insufficiency indication 373662000 DOID:13774
Adrenal cortical hypofunction indication 386584007 DOID:10493
Herpes zoster keratitis indication 397573005
Rosacea indication 398909004 DOID:8881
Erythroderma indication 399992009
Primary cutaneous T-cell lymphoma indication 400122007
Allergic otitis externa indication 405821001
Anterior uveitis indication 410692006 DOID:1407
Autoimmune hemolytic anemia indication 413603009 DOID:718
Allergic conjunctivitis indication 473460002 DOID:11204
Otitis Externa Eczema indication
Post-Op Ocular Inflammation indication
Synovitis due to Osteoarthritis indication
Tuberculosis Meningitis Treatment Adjunct indication
Transfusion Reaction Urticaria indication
Systemic Dermatomyositis indication
Staphylococcus Aureus Otitis Externa indication
Non-infectious Posterior Uveitis indication
Diagnostic Test for Cushing's Syndrome indication
Progressive Diffuse Large B-Cell Lymphoma indication
Otitis Externa Seborrhea indication
Erythroblastic Anemia indication
Infection by Strongyloides contraindication 1214006 DOID:10955
Endophthalmitis contraindication 1847009 DOID:4692
Mycosis contraindication 3218000 DOID:1564
Ocular hypertension contraindication 4210003 DOID:9282
Gastritis contraindication 4556007 DOID:4029
Herpes simplex keratitis contraindication 9389005
Inactive tuberculosis contraindication 11999007
Peptic ulcer contraindication 13200003 DOID:750
Hypercholesterolemia contraindication 13644009
Measles contraindication 14189004 DOID:8622
Cirrhosis of liver contraindication 19943007 DOID:5082
Arginase deficiency contraindication 23501004 DOID:9278
Glaucoma contraindication 23986001 DOID:1686
Herpes simplex dendritic keratitis contraindication 29943008
Fungal infection of eye contraindication 31194008
Severe myopia contraindication 34187009
Immunosuppression contraindication 38013005
Hypertensive disorder contraindication 38341003 DOID:10763
Infectious disease contraindication 40733004
Hypothyroidism contraindication 40930008 DOID:1459
Retinal detachment contraindication 42059000 DOID:5327
Hypokalemia contraindication 43339004
Chronic heart failure contraindication 48447003
Tuberculosis of eye contraindication 49107007
Cerebral malaria contraindication 53622003 DOID:14069
Tuberculosis contraindication 56717001
Congenital hyperammonemia, type I contraindication 62522004 DOID:9280
Osteoporosis contraindication 64859006 DOID:11476
Psychotic disorder contraindication 69322001
Diabetes mellitus contraindication 73211009 DOID:9351
Hypopituitarism contraindication 74728003 DOID:9406
Hyperglycemia contraindication 80394007 DOID:4195
Open-angle glaucoma contraindication 84494001 DOID:1067
Krukenberg spindle contraindication 85430004
Muscle atrophy contraindication 88092000 DOID:767
Herpes simplex contraindication 88594005 DOID:8566
Bilateral cataracts contraindication 95722004
Eye infection contraindication 128351009
Seizure disorder contraindication 128613002 DOID:1826
Bacterial infection of eye contraindication 128984004
Disorder of muscle contraindication 129565002 DOID:423
Ophthalmic herpes simplex contraindication 186542001
Anastomosis of intestine contraindication 235407009
Telangiectasia disorder contraindication 247479008 DOID:1272
Edema contraindication 267038008
Pathological fracture contraindication 268029009
Diverticulitis of gastrointestinal tract contraindication 271366000
Cerebral trauma contraindication 275382005
Injury of eye region contraindication 282752000
Varicella-zoster virus infection contraindication 309465005
Viral eye infection contraindication 312132001
Viral ear infection contraindication 312137007
Osteopenia contraindication 312894000
Vaccinia keratitis contraindication 397552005
Avascular necrosis of bone contraindication 397758007 DOID:10159
Citrullinemia contraindication 398680004 DOID:9273
Atrophoderma contraindication 399979006 DOID:2733
Peripheral vascular disease contraindication 400047006
Traumatic rupture of tendon contraindication 415749005
Exposure to varicella contraindication 444453009
Ornithine Carbamyltransferase Deficiency contraindication
Arginosuccinate Lyase Deficiency contraindication
Pericarditis off-label use 3238004 DOID:1787
West syndrome off-label use 28055006 DOID:2481
Vasculitis off-label use 31996006 DOID:865
Tendinitis off-label use 34840004 DOID:971
Eczema off-label use 43116000 DOID:2723
Respiratory distress syndrome in the newborn off-label use 46775006 DOID:12716
Nasal polyp off-label use 52756005
Rheumatic fever off-label use 58718002 DOID:1586
Pseudogout off-label use 60782007 DOID:1156
Polymyalgia rheumatica off-label use 65323003 DOID:853
Croup off-label use 71186008 DOID:9395
Pemphigoid off-label use 86142006 DOID:8506
Myasthenia gravis off-label use 91637004 DOID:437
Polyarteritis nodosa off-label use 155441006 DOID:9810
Chemotherapy-induced nausea and vomiting off-label use 236084000
Celiac disease off-label use 396331005 DOID:10608
Carditis off-label use 399617002
Giant cell arteritis off-label use 414341000 DOID:13375
Prevention of Post-Operative Nausea and Vomiting off-label use
Metastatic Prostate Carcinoma off-label use
Hypercalcemia associated with Sarcoidosis off-label use
Prevention of Radiation-Induced Nausea and Vomiting off-label use

Acid dissociation constants calculated using MoKa v3.0.0

scroll-->
Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.06 acidic
pKa2 12.45 acidic

Orange Book patent data (new drug applications)

scroll-->
Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 6726918 Oct. 20, 2020 TREATMENT OF MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 6726918 Oct. 20, 2020 TREATMENT OF UVEITIS
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 8043628 Oct. 20, 2020 TREATMENT OF MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 8088407 Oct. 20, 2020 TREATMENT OF MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 9012437 Oct. 20, 2020 TREATMENT OF MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 9283178 Oct. 20, 2020 TREATMENT OF MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 9592242 Oct. 20, 2020 INTRAVITREAL TREATMENT OF DIABETIC MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 9592242 Oct. 20, 2020 INTRAVITREAL TREATMENT OF MACULAR EDEMA FOLLOWING BRANCH RETINAL VEIN OCCLUSION (BRVO) OR CENTRAL RETINAL VEIN OCCLUSION (CRVO)
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 9775849 Oct. 20, 2020 INTRAVITREAL TREATMENT OF DIABETIC MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 9775849 Oct. 20, 2020 INTRAVITREAL TREATMENT OF MACULAR EDEMA FOLLOWING BRANCH RETINAL VEIN OCCLUSION (BRVO) OR CENTRAL RETINAL VEIN OCCLUSION (CRVO)
0.1% CIPRODEX NOVARTIS PHARMS CORP N021537 July 18, 2003 RX SUSPENSION/DROPS OTIC 9149486 Sept. 13, 2022 TREATMENT OF ACUTE OTITIS MEDIA
0.1% CIPRODEX NOVARTIS PHARMS CORP N021537 July 18, 2003 RX SUSPENSION/DROPS OTIC 9345714 Sept. 13, 2022 TREATMENT OF ACUTE OTITIS MEDIA
0.1% CIPRODEX NOVARTIS PHARMS CORP N021537 July 18, 2003 RX SUSPENSION/DROPS OTIC 9402805 Sept. 13, 2022 TREATMENT OF ACUTE OTITIS EXTERNA
0.1% CIPRODEX NOVARTIS PHARMS CORP N021537 July 18, 2003 RX SUSPENSION/DROPS OTIC 9402805 Sept. 13, 2022 TREATMENT OF ACUTE OTITIS MEDIA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 8034366 Jan. 9, 2023 TREATMENT OF MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 8034366 Jan. 9, 2023 TREATMENT OF UVEITIS
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 8506987 Jan. 9, 2023 TREATMENT OF MACULAR EDEMA
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 8506987 Jan. 9, 2023 TREATMENT OF UVEITIS
0.7MG OZURDEX ALLERGAN N022315 June 17, 2009 RX IMPLANT INTRAVITREAL 6899717 Nov. 1, 2023 DELIVERING AN OCULAR IMPLANT AS DESCRIBED IN THE DOSAGE AND ADMINISTRATION SECTION OF THE APPROVED LABELING OF OZURDEX
0.1% CIPRODEX NOVARTIS PHARMS CORP N021537 July 18, 2003 RX SUSPENSION/DROPS OTIC 8846650 June 4, 2025 TREATMENT OF ACUTE OTITIS MEDIA
0.05% TOBRADEX ST NOVARTIS PHARMS CORP N050818 Feb. 13, 2009 RX SUSPENSION/DROPS OPHTHALMIC 8101582 Dec. 19, 2027 USE OF A COMBINATION OF TOBRAMYCIN AND DEXAMETHASONE TO TREAT OCULAR INFLAMMATION WHERE AN INFECTION OR RISK OF INFECTION EXISTS
0.05% TOBRADEX ST NOVARTIS PHARMS CORP N050818 Feb. 13, 2009 RX SUSPENSION/DROPS OPHTHALMIC 7795316 Aug. 3, 2028 USE OF A COMBINATION OF TOBRAMYCIN AND DEXAMETHASONE TO TREAT OCULAR INFLAMMATION WHERE AN INFECTION OR RISK OF INFECTION EXISTS

Orange Book exclusivity data (new drug applications)

scroll-->
Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
9% DEXYCU KIT ICON BIOSCIENCE N208912 Feb. 9, 2018 RX SUSPENSION INTRAOCULAR Feb. 9, 2021 NEW PRODUCT

Bioactivity Summary:

scroll-->
TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST EC50 8.88 WOMBAT-PK CHEMBL
Interleukin-5 Cytokine IC50 8.46 WOMBAT-PK
Mineralocorticoid receptor Nuclear hormone receptor EC50 9 WOMBAT-PK
Annexin A1 Cytosolic other WOMBAT-PK
Progesterone receptor Nuclear hormone receptor Ki 6.25 CHEMBL
Androgen receptor Nuclear hormone receptor Ki 5.85 CHEMBL
Prostaglandin G/H synthase 2 Enzyme Ki 6.89 PDSP
Interleukin-4 Cytokine IC50 8.33 WOMBAT-PK
Androgen receptor Transcription factor Ki 4.79 DRUG MATRIX
Progesterone receptor Transcription factor Ki 5.52 DRUG MATRIX
Fatty acid-binding protein, liver Unclassified Ki 4.66 CHEMBL
Glucocorticoid receptor Transcription factor IC50 7.66 CHEMBL
Nuclear receptor subfamily 1 group I member 2 Nuclear hormone receptor AGONIST EC50 6.10 IUPHAR

External reference:

scroll-->
IDSource
2768 IUPHAR_LIGAND_ID
4017922 VUID
N0000146273 NUI
C0011777 UMLSCUI
D00292 KEGG_DRUG
7S5I7G3JQL UNII
816 INN_ID
4017922 VANDF
N0000146273 NDFRT
N0000006127 NDFRT
002174 NDDF
7561000 SNOMEDCT_US
6848 MMSL
3264 RXNORM
372584003 SNOMEDCT_US
4552 MMSL
d00206 MMSL
CHEMBL384467 ChEMBL_ID
5743 PUBCHEM_CID
CHEMBL1200637 ChEMBL_ID
D003907 MESH_DESCRIPTOR_UI
DB01234 DRUGBANK_ID
CHEBI:41879 CHEBI
DEX PDB_CHEM_ID

Pharmaceutical products:

scroll-->
ProductCategoryIngredientsNDCFormQuantityRoute MarketingLabel
OZURDEX HUMAN PRESCRIPTION DRUG LABEL 1 0023-3348 IMPLANT 0.70 mg INTRAVITREAL NDA 15 sections
Dexamethasone Intensol HUMAN PRESCRIPTION DRUG LABEL 1 0054-3176 SOLUTION, CONCENTRATE 1 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-3177 SOLUTION 0.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-4179 TABLET 0.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-4180 TABLET 0.75 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-4181 TABLET 1 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-4182 TABLET 1.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-4183 TABLET 2 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-4184 TABLET 4 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-4186 TABLET 6 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-8174 TABLET 1 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-8175 TABLET 4 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-8176 TABLET 2 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-8179 TABLET 0.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-8180 TABLET 0.75 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-8181 TABLET 1.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0054-8183 TABLET 6 mg ORAL ANDA 11 sections
MAXITROL HUMAN PRESCRIPTION DRUG LABEL 3 0065-0631 OINTMENT 1 mg OPHTHALMIC NDA 11 sections
TobraDex HUMAN PRESCRIPTION DRUG LABEL 2 0065-0647 SUSPENSION/ DROPS 1 mg OPHTHALMIC NDA 12 sections
TobraDex HUMAN PRESCRIPTION DRUG LABEL 2 0065-0648 OINTMENT 1 mg OPHTHALMIC NDA 13 sections
TOBRADEX ST HUMAN PRESCRIPTION DRUG LABEL 2 0065-0652 SUSPENSION/ DROPS 0.50 mg OPHTHALMIC NDA 14 sections
CIPRODEX HUMAN PRESCRIPTION DRUG LABEL 2 0065-8533 SUSPENSION/ DROPS 1 mg AURICULAR (OTIC) NDA 16 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0095-0087 TABLET 1.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0095-0088 TABLET 1.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 0095-0089 TABLET 1.50 mg ORAL ANDA 11 sections
Neomycin and Polymyxin B Sulfates and Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 3 0574-4160 OINTMENT 1 mg OPHTHALMIC ANDA 14 sections
Maxidex HUMAN PRESCRIPTION DRUG LABEL 1 0998-0615 SUSPENSION 1 mg OPHTHALMIC NDA 11 sections
Maxitrol HUMAN PRESCRIPTION DRUG LABEL 3 0998-0630 SUSPENSION 1 mg OPHTHALMIC NDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 10544-211 TABLET 1.50 mg ORAL ANDA 11 sections
Dexamethasone HUMAN PRESCRIPTION DRUG LABEL 1 10544-212 TABLET 4 mg ORAL ANDA 11 sections