acitazanolast indications/contra

Stem definitionDrug idCAS RN
antiasthmatics or antiallergics, not acting primarily as antihistaminics 77 114607-46-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acitazanolast hydrate
  • WP-871
  • zepelin
  • acitazanolast
a leukotriene D4 antagonist
  • Molecular weight: 233.19
  • Formula: C9H7N5O3
  • CLOGP: -0.59
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 120.86
  • ALOGS: -3.27
  • ROTB: 3

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Allergic conjunctivitis indication 473460002 DOID:11204

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.6 acidic
pKa2 4.3 acidic
pKa3 11.63 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D03233 KEGG_DRUG
2006 PUBCHEM_CID
010983 NDDF
99Y8VJ356G UNII
7216 INN_ID
CHEBI:134948 CHEBI
C065288 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2104654 ChEMBL_ID

Pharmaceutical products:

None