acitazanolast 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiasthmatics or antiallergics, not acting primarily as antihistaminics anti-allergic or anti-inflammatory, not acting as anti-histaminics 77 114607-46-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acitazanolast hydrate
  • WP-871
  • zepelin
  • acitazanolast
a leukotriene D4 antagonist
  • Molecular weight: 233.19
  • Formula: C9H7N5O3
  • CLOGP: -0.59
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 120.86
  • ALOGS: -3.27
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Allergic conjunctivitis indication 473460002 DOID:11204




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.6 acidic
pKa2 4.3 acidic
pKa3 11.63 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03233 KEGG_DRUG
C0642373 UMLSCUI
CHEBI:134948 CHEBI
CHEMBL2104654 ChEMBL_ID
2006 PUBCHEM_CID
C065288 MESH_SUPPLEMENTAL_RECORD_UI
7216 INN_ID
99Y8VJ356G UNII
D011298 MESH_DESCRIPTOR_UI
010983 NDDF

Pharmaceutical products:

None