cyclandelate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
spasmolytics with a papaverine-like action 747 456-59-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cyclandelate
  • cyclergine
  • cyclobral
  • cyclolyt
  • cyclomandol
A direct-acting SMOOTH MUSCLE relaxant used to dilate BLOOD VESSELS.
  • Molecular weight: 276.38
  • Formula: C17H24O3
  • CLOGP: 4.64
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 46.53
  • ALOGS: -3.44
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.60 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C04AX01 CARDIOVASCULAR SYSTEM
PERIPHERAL VASODILATORS
PERIPHERAL VASODILATORS
Other peripheral vasodilators
CHEBI has role CHEBI:35620 vasodilator agents
MeSH PA D002317 Cardiovascular Agents
MeSH PA D014665 Vasodilator Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.82 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018058 VUID
N0000146399 NUI
D00286 KEGG_DRUG
2970 RXNORM
4018058 VANDF
C0010525 UMLSCUI
CHEBI:3988 CHEBI
CHEMBL1480987 ChEMBL_ID
DB04838 DRUGBANK_ID
D003495 MESH_DESCRIPTOR_UI
2893 PUBCHEM_CID
821 INN_ID
4139O1OAY2 UNII
212 MMSL
4515 MMSL
d00692 MMSL
000696 NDDF
387405003 SNOMEDCT_US
72312007 SNOMEDCT_US

Pharmaceutical products:

None