crotamiton 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
744 483-63-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • crotamiton
  • crotalgin
  • crotamitex
  • crotamitone
  • veteusan
  • N-Crotonyl-N-ethyl-o-toluidine
antiscabies, antipruritic drug; active ingredient in Eurax Cream & Lotion (Geigy); request from searcher 3/76; structure
  • Molecular weight: 203.29
  • Formula: C13H17NO
  • CLOGP: 3.43
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 0
  • TPSA: 20.31
  • ALOGS: -2.76
  • ROTB: 3

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 6, 1949 FDA RANBAXY

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D010575 Pesticides
CHEBI has role CHEBI:59683 antipruritic drugs
CHEBI has role CHEBI:73333 scabicides

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Infestation by Sarcoptes scabiei var hominis indication 128869009 DOID:8295
Itching of skin indication 418363000
Denuded skin contraindication 418242004
Inflammatory dermatosis contraindication 703938007




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018661 VUID
N0000146972 NUI
D01381 KEGG_DRUG
21766 RXNORM
4018661 VANDF
C0056519 UMLSCUI
CHEBI:31439 CHEBI
CHEMBL1200709 ChEMBL_ID
DB00265 DRUGBANK_ID
688020 PUBCHEM_CID
C005553 MESH_SUPPLEMENTAL_RECORD_UI
11165 IUPHAR_LIGAND_ID
673 INN_ID
D6S4O4XD0H UNII
4511 MMSL
002993 NDDF
387515007 SNOMEDCT_US
89692007 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Crotan HUMAN PRESCRIPTION DRUG LABEL 1 0682-0051 LOTION 100 mg TOPICAL ANDA 19 sections
Crotan HUMAN PRESCRIPTION DRUG LABEL 1 0682-0051 LOTION 100 mg TOPICAL ANDA 19 sections