acetylleucine indications/contra

Stem definitionDrug idCAS RN
71 99-15-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acetylleucine
  • (S)-2-Acetamido-4-methylpentanoic acid
  • Acetyl-L-leucine
  • N-Acetylleucine
used for treating vestibular-related imbalance and vertigo
  • Molecular weight: 173.21
  • Formula: C8H15NO3
  • CLOGP: 0.86
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 66.40
  • ALOGS: -1.20
  • ROTB: 4

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC N07CA04 NERVOUS SYSTEM
OTHER NERVOUS SYSTEM DRUGS
ANTIVERTIGO PREPARATIONS
Antivertigo preparations

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.9 acidic
pKa2 13.57 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
CHEBI:17786 CHEBI
D07350 KEGG_DRUG
CHEMBL56021 ChEMBL_ID
005881 NDDF
CHEMBL1875805 ChEMBL_ID
K76S41V71X UNII
5209 INN_ID
C088117 MESH_SUPPLEMENTAL_RECORD_UI
1995 PUBCHEM_CID
LAY PDB_CHEM_ID

Pharmaceutical products:

None