chlorozotocin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
612 54749-90-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chlorozotocin
  • chlorozotocine
2-chloroethyl analog of streptozotocin with superior activity against leukemia L1210 and reduced bone marrow toxicity; RN given refers to (D)-isomer; structure
  • Molecular weight: 313.69
  • Formula: C9H16ClN3O7
  • CLOGP: -0.82
  • LIPINSKI: 0
  • HAC: 10
  • HDO: 5
  • TPSA: 151.92
  • ALOGS: -1.05
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000970 Antineoplastic Agents
MeSH PA D002273 Carcinogens
MeSH PA D009676 Noxae

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.1 acidic
pKa2 12.31 acidic
pKa3 12.95 acidic
pKa4 13.57 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
1362886 RXNORM
C0055465 UMLSCUI
CHEBI:82277 CHEBI
CHEMBL2094020 ChEMBL_ID
C007028 MESH_SUPPLEMENTAL_RECORD_UI
3053LTY75Z UNII

Pharmaceutical products:

None