cefaloglycin indications/contra

Stem definitionDrug idCAS RN
antibiotics, cefalosporanic acid derivatives 572 3577-01-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cephaloglycin
  • cefaloglycin
  • cefaloglycine
  • cephaloglycine
  • kefglycin
  • kafocin
A cephalorsporin antibiotic.
  • Molecular weight: 405.43
  • Formula: C18H19N3O6S
  • CLOGP: -2.56
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 3
  • TPSA: 139.03
  • ALOGS: -3.44
  • ROTB: 7

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
June 12, 1970 FDA LILLY

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.39 acidic
pKa2 13.53 acidic
pKa3 7.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Bacterial penicillin-binding protein Enzyme INHIBITOR CHEMBL CHEMBL

External reference:

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IDSource
D01949 KEGG_DRUG
DB00689 DRUGBANK_ID
N0000166879 NDFRT
002714 NDDF
39123009 SNOMEDCT_US
19150 PUBCHEM_CID
CHEMBL1200971 ChEMBL_ID
D002507 MESH_DESCRIPTOR_UI
NE7R11LA95 UNII
22202-75-1 SECONDARY_CAS_RN
CHEBI:34613 CHEBI

Pharmaceutical products:

None