celecoxib Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
selective cyclo-oxygenase inhibitors 568 169590-42-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • celecoxib
  • celebrex
  • celecox
  • celocoxib
  • onsenal
A pyrazole derivative and selective CYCLOOXYGENASE 2 INHIBITOR that is used to treat symptoms associated with RHEUMATOID ARTHRITIS; OSTEOARTHRITIS and JUVENILE ARTHRITIS, as well as the management of ACUTE PAIN.
  • Molecular weight: 381.37
  • Formula: C17H14F3N3O2S
  • CLOGP: 4.37
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 77.98
  • ALOGS: -4.88
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.20 g O

Approvals:

DateAgencyCompanyOrphan
Dec. 31, 1998 FDA GD SEARLE

FDA Adverse Event Reporting System

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug hypersensitivity 8902.58 22.52 2606 12525 65794 4558067
Drug ineffective 3151.69 22.52 1620 13511 184441 4439420
Rheumatoid arthritis 1727.40 22.52 598 14533 24401 4599460
Pain 1236.02 22.52 696 14435 92174 4531687
Rash 1049.34 22.52 662 14469 107726 4516135
Gastrointestinal haemorrhage 994.80 22.52 423 14708 30112 4593749
Condition aggravated 992.43 22.52 515 14616 57656 4566205
Arthralgia 962.27 22.52 567 14564 81427 4542434
Drug intolerance 862.66 22.52 347 14784 21399 4602462
Nausea 802.24 22.52 684 14447 176649 4447212
Myocardial infarction 758.42 22.52 408 14723 48968 4574893
Therapeutic product effect decreased 660.57 22.52 275 14856 18478 4605383
Loss of personal independence in daily activities 616.48 22.52 209 14922 7896 4615965
Therapeutic product effect incomplete 611.57 22.52 254 14877 16954 4606907
Pain in extremity 568.63 22.52 371 14760 63368 4560493
Hypersensitivity 551.79 22.52 304 14827 38117 4585744
Arthropathy 519.82 22.52 198 14933 10500 4613361
Pruritus 510.97 22.52 365 14766 72207 4551654
Contraindicated product administered 496.83 22.52 159 14972 4992 4618869
Abdominal discomfort 481.24 22.52 251 14880 28157 4595704
Joint swelling 475.53 22.52 236 14895 23842 4600019
Vomiting 469.11 22.52 427 14704 119272 4504589
Anaphylactic reaction 468.31 22.52 213 14918 17697 4606164
Urticaria 465.64 22.52 275 14856 39298 4584563
Osteoarthritis 453.07 22.52 174 14957 9430 4614431
Diarrhoea 433.49 22.52 453 14678 149732 4474129
Dyspnoea 420.39 22.52 430 14701 138555 4485306
Infection 414.21 22.52 247 14884 35895 4587966
Arthritis 413.41 22.52 184 14947 14516 4609345
Swelling 407.89 22.52 214 14917 24268 4599593
Chest pain 398.32 22.52 273 14858 50427 4573434
Acute kidney injury 396.57 22.52 310 14821 70121 4553740
Malaise 381.06 22.52 336 14795 89821 4534040
Renal impairment 367.47 22.52 202 14929 25136 4598725
Drug interaction 356.67 22.52 281 14850 64227 4559634
Cerebrovascular accident 350.83 22.52 235 14896 41765 4582096
Atrial fibrillation 343.70 22.52 208 14923 31007 4592854
Abdominal pain upper 343.56 22.52 217 14914 34898 4588963
Dizziness 340.16 22.52 330 14801 99541 4524320
Erythema 334.36 22.52 228 14903 41712 4582149
Presbyacusis 334.03 22.52 56 15075 48 4623813
Gait disturbance 330.18 22.52 215 14916 36425 4587436
Hypertension 323.95 22.52 241 14890 50557 4573304
Gastric ulcer 321.43 22.52 120 15011 6003 4617858
Renal failure 320.55 22.52 221 14910 41148 4582713
Asthenia 320.46 22.52 299 14832 85864 4537997
Drug eruption 309.04 22.52 119 15012 6484 4617377
Musculoskeletal stiffness 308.36 22.52 163 14968 18739 4605122
International normalised ratio fluctuation 291.79 22.52 67 15064 558 4623303
Gastrointestinal disorder 283.38 22.52 146 14985 15915 4607946
Ankylosing spondylitis 282.69 22.52 79 15052 1533 4622328
Oedema peripheral 280.70 22.52 205 14926 41767 4582094
Gastric disorder 271.66 22.52 105 15026 5777 4618084
Treatment failure 268.19 22.52 135 14996 14012 4609849
Mobility decreased 268.03 22.52 132 14999 13073 4610788
Back pain 259.32 22.52 211 14920 50388 4573473
Pleural thickening 257.16 22.52 47 15084 96 4623765
Headache 256.21 22.52 313 14818 122060 4501801
Fatigue 253.97 22.52 340 14791 145226 4478635
Anaemia 253.71 22.52 242 14889 71318 4552543
Hypoaesthesia 251.85 22.52 172 14959 31493 4592368
Fall 250.65 22.52 250 14881 77796 4546065
Pleural fibrosis 248.81 22.52 56 15075 422 4623439
Pneumonia 239.85 22.52 278 14853 102537 4521324
Osteopenia 235.14 22.52 77 15054 2597 4621264
Blood creatinine increased 230.35 22.52 153 14978 26747 4597114
Insomnia 225.78 22.52 186 14945 45159 4578702
Gastrooesophageal reflux disease 224.76 22.52 122 15009 14771 4609090
Osteoporosis 224.07 22.52 94 15037 6401 4617460
Abdominal pain 220.29 22.52 207 14924 59817 4564044
Blood pressure increased 217.73 22.52 153 14978 29307 4594554
Blood magnesium increased 214.80 22.52 47 15084 306 4623555
Stevens-Johnson syndrome 213.81 22.52 99 15032 8540 4615321
Gastric ulcer haemorrhage 211.42 22.52 66 15065 1902 4621959
Bedridden 208.03 22.52 67 15064 2141 4621720
Deafness neurosensory 202.83 22.52 58 15073 1226 4622635
Anaphylactic shock 200.57 22.52 92 15039 7765 4616096
Loss of consciousness 198.00 22.52 156 14975 35526 4588335
Haemorrhage 196.45 22.52 136 14995 25426 4598435
Muscle spasms 194.44 22.52 154 14977 35336 4588525
Renal disorder 193.82 22.52 95 15036 9301 4614560
Epigastric discomfort 192.21 22.52 53 15078 976 4622885
Haematemesis 191.24 22.52 93 15038 8950 4614911
Pyrexia 189.15 22.52 252 14879 106892 4516969
Swelling face 186.98 22.52 108 15023 14732 4609129
Stress 185.75 22.52 94 15037 9854 4614007
Dyspepsia 184.30 22.52 110 15021 15944 4607917
Peripheral swelling 181.95 22.52 132 14999 26560 4597301
Weight decreased 181.18 22.52 178 14953 54286 4569575
Dry eye 181.03 22.52 77 15054 5424 4618437
Sleep disorder 180.37 22.52 96 15035 11167 4612694
Blood potassium increased 179.97 22.52 75 15056 5020 4618841
Depression 179.62 22.52 167 14964 47566 4576295
Palpitations 178.82 22.52 127 15004 24719 4599142
Melaena 176.93 22.52 91 15040 9867 4613994
Feeling abnormal 176.27 22.52 147 14984 36258 4587603
Arrhythmia 173.85 22.52 100 15031 13532 4610329
Cardiac disorder 170.25 22.52 107 15024 17002 4606859
Blood cholesterol increased 167.62 22.52 84 15047 8622 4615239
Fibromyalgia 165.38 22.52 65 15066 3736 4620125
Interstitial lung disease 163.35 22.52 109 15022 19176 4604685
Cyst 162.38 22.52 57 15074 2381 4621480
Gait inability 162.01 22.52 85 15046 9600 4614261
Deformity 158.78 22.52 42 15089 656 4623205
Nephrolithiasis 153.10 22.52 80 15051 8959 4614902
Intentional product misuse 152.96 22.52 103 15028 18390 4605471
Paraesthesia 151.96 22.52 133 14998 35000 4588861
Erythema multiforme 151.96 22.52 63 15068 4160 4619701
Hypermobility syndrome 151.34 22.52 28 15103 63 4623798
Cough 151.06 22.52 163 14968 55424 4568437
Hypotension 149.78 22.52 178 14953 67222 4556639
Nasopharyngitis 147.21 22.52 128 15003 33389 4590472
Impaired work ability 146.87 22.52 56 15075 2964 4620897
Weight increased 145.36 22.52 132 14999 36449 4587412
Oedema 144.56 22.52 100 15031 18651 4605210
Skin lesion 143.01 22.52 72 15059 7461 4616400
Immobile 142.36 22.52 42 15089 994 4622867
Pharyngeal oedema 142.35 22.52 65 15066 5424 4618437
Fracture 141.59 22.52 61 15070 4432 4619429
Disease recurrence 137.98 22.52 70 15061 7371 4616490
Gastritis 137.35 22.52 72 15059 8114 4615747
Swollen tongue 132.84 22.52 72 15059 8678 4615183
Migraine 132.02 22.52 84 15047 13625 4610236
Face oedema 130.10 22.52 65 15066 6625 4617236
Nerve injury 129.81 22.52 44 15087 1652 4622209
Lower limb fracture 129.27 22.52 51 15080 2960 4620901
Upper gastrointestinal haemorrhage 129.00 22.52 61 15070 5512 4618349
Confusional state 128.80 22.52 141 14990 48693 4575168
Back disorder 128.19 22.52 49 15082 2611 4621250
Exostosis 127.81 22.52 45 15086 1896 4621965
Musculoskeletal pain 126.77 22.52 88 15043 16500 4607361
Haemoglobin decreased 124.98 22.52 123 15008 37534 4586327
Rectal haemorrhage 122.54 22.52 77 15054 12219 4611642
Urinary retention 122.24 22.52 71 15060 9776 4614085
Contusion 121.63 22.52 91 15040 19167 4604694
Transient ischaemic attack 121.43 22.52 75 15056 11547 4612314
Bone cyst 119.97 22.52 28 15103 252 4623609
Haematochezia 117.12 22.52 72 15059 10992 4612869
Body height decreased 116.52 22.52 41 15090 1724 4622137
Disease progression 116.18 22.52 123 15008 40888 4582973
Foot fracture 116.12 22.52 50 15081 3627 4620234
Knee arthroplasty 115.42 22.52 51 15080 3938 4619923
Drug-induced liver injury 114.81 22.52 65 15066 8526 4615335
Constipation 113.38 22.52 123 15008 42031 4581830
Diverticulitis 112.53 22.52 60 15071 6997 4616864
Asthma 111.73 22.52 83 15048 17291 4606570
Cardiac failure 111.37 22.52 100 15031 27188 4596673
Toxic skin eruption 110.85 22.52 51 15080 4329 4619532
Angina pectoris 110.82 22.52 66 15065 9515 4614346
Crohn's disease 110.28 22.52 71 15060 11748 4612113
Dehydration 109.57 22.52 121 15010 42169 4581692
Osteosclerosis 108.16 22.52 29 15102 478 4623383
Rash erythematous 107.72 22.52 67 15064 10442 4613419
Anxiety 105.24 22.52 126 15005 47885 4575976
Ulcer 104.53 22.52 45 15086 3262 4620599
Foot deformity 104.47 22.52 42 15089 2561 4621300
Neck pain 104.35 22.52 68 15063 11484 4612377
C-reactive protein increased 102.67 22.52 70 15061 12742 4611119
Joint range of motion decreased 102.47 22.52 42 15089 2692 4621169
Inflammation 102.11 22.52 64 15067 10107 4613754
Product use in unapproved indication 101.91 22.52 92 15039 25181 4598680
Cataract 100.13 22.52 62 15069 9584 4614277
Off label use 100.09 22.52 210 14921 128903 4494958
Aspartate aminotransferase increased 99.03 22.52 90 15041 24848 4599013
Epicondylitis 98.40 22.52 26 15105 404 4623457
Acute myocardial infarction 97.30 22.52 71 15060 14388 4609473
Alanine aminotransferase increased 96.57 22.52 94 15037 28279 4595582
Coronary artery occlusion 96.50 22.52 43 15088 3386 4620475
Pulmonary fibrosis 95.81 22.52 50 15081 5580 4618281
General physical health deterioration 95.45 22.52 94 15037 28684 4595177
Upper limb fracture 93.71 22.52 43 15088 3627 4620234
Product use issue 92.90 22.52 87 15044 24949 4598912
Somnolence 91.46 22.52 112 15019 43548 4580313
Cardiac arrest 91.01 22.52 99 15032 33908 4589953
Bloody discharge 90.10 22.52 22 15109 244 4623617
Cardiovascular disorder 89.26 22.52 48 15083 5692 4618169
Completed suicide 89.10 22.52 109 15022 42336 4581525
Cerebral infarction 88.73 22.52 60 15071 10772 4613089
Vertigo 88.52 22.52 68 15063 14888 4608973
Synovitis 88.18 22.52 41 15090 3564 4620297
Post procedural haemorrhage 87.97 22.52 39 15092 3034 4620827
Duodenal ulcer 87.28 22.52 39 15092 3091 4620770
Peptic ulcer 87.21 22.52 30 15101 1178 4622683
Faeces discoloured 85.64 22.52 45 15086 5092 4618769
Pulmonary embolism 83.16 22.52 95 15036 34331 4589530
Blister 83.12 22.52 59 15072 11450 4612411
Chest discomfort 82.95 22.52 79 15052 23131 4600730
Liver disorder 82.92 22.52 62 15069 13036 4610825
Fine motor skill dysfunction 82.67 22.52 23 15108 438 4623423
Dysphagia 82.07 22.52 82 15049 25449 4598412
Bone erosion 81.88 22.52 26 15105 792 4623069
Gastric haemorrhage 81.36 22.52 41 15090 4253 4619608
Syncope 80.40 22.52 92 15039 33303 4590558
Angioedema 79.77 22.52 72 15059 19693 4604168
Hyperkalaemia 78.73 22.52 65 15066 15772 4608089
Blood pressure decreased 77.79 22.52 68 15063 17832 4606029
Blood urea increased 77.78 22.52 51 15080 8699 4615162
Movement disorder 77.22 22.52 41 15090 4738 4619123
Burning sensation 76.95 22.52 57 15074 11815 4612046
Thyroid neoplasm 76.76 22.52 25 15106 827 4623034
Rash maculo-papular 76.51 22.52 50 15081 8479 4615382
Neuralgia 76.33 22.52 40 15091 4500 4619361
Diabetes mellitus 75.77 22.52 63 15068 15438 4608423
Chronic obstructive pulmonary disease 75.74 22.52 60 15071 13734 4610127
Product substitution issue 74.86 22.52 51 15080 9267 4614594
Muscular weakness 74.02 22.52 79 15052 26471 4597390
Colitis 73.93 22.52 53 15078 10446 4613415
Tinnitus 73.40 22.52 50 15081 9083 4614778
Deep vein thrombosis 73.10 22.52 77 15054 25417 4598444
International normalised ratio increased 72.75 22.52 64 15067 16924 4606937
Pancreatitis 72.13 22.52 64 15067 17114 4606747
Cardiac failure congestive 71.44 22.52 86 15045 32836 4591025
Eye disorder 71.43 22.52 40 15091 5134 4618727
Therapeutic response decreased 71.19 22.52 59 15072 14392 4609469
Dermatitis 70.83 22.52 38 15093 4483 4619378
Toxicity to various agents 70.04 22.52 129 15002 71911 4551950
Shock 69.73 22.52 48 15083 8868 4614993
Lyme disease 69.63 22.52 22 15109 659 4623202
Hepatic enzyme increased 69.59 22.52 64 15067 17927 4605934
Intervertebral disc protrusion 69.28 22.52 38 15093 4684 4619177
Coma 69.08 22.52 63 15068 17456 4606405
Thrombosis 68.34 22.52 64 15067 18340 4605521
Purpura 68.32 22.52 35 15096 3757 4620104
Musculoskeletal disorder 68.30 22.52 35 15096 3760 4620101
Colitis ischaemic 66.56 22.52 31 15100 2704 4621157
Hyperhidrosis 66.30 22.52 79 15052 29838 4594023
Coronary artery stenosis 65.95 22.52 30 15101 2479 4621382
Jaundice 65.79 22.52 53 15078 12421 4611440
Tachycardia 65.36 22.52 80 15051 31065 4592796
Rotator cuff syndrome 65.32 22.52 31 15100 2821 4621040
Coronary artery disease 65.17 22.52 59 15072 16193 4607668
Thrombocytopenia 64.51 22.52 99 15032 47574 4576287
Urinary tract infection 64.48 22.52 93 15038 42297 4581564
Herpes zoster 64.42 22.52 58 15073 15805 4608056
Influenza 63.74 22.52 65 15066 20658 4603203
Sepsis 63.73 22.52 93 15038 42746 4581115
Blood alkaline phosphatase increased 63.56 22.52 52 15079 12455 4611406
Duodenal ulcer haemorrhage 63.49 22.52 24 15107 1239 4622622
Red blood cell sedimentation rate increased 63.48 22.52 32 15099 3321 4620540
Diverticulum 63.45 22.52 30 15101 2707 4621154
Hepatic function abnormal 63.04 22.52 55 15076 14381 4609480
Myalgia 62.14 22.52 91 15040 41957 4581904
Drug ineffective for unapproved indication 61.95 22.52 38 15093 5773 4618088
Abdominal distension 61.94 22.52 60 15071 17929 4605932
Photosensitivity reaction 61.79 22.52 35 15096 4591 4619270
Tremor 61.77 22.52 84 15047 36175 4587686
Product prescribing error 61.72 22.52 41 15090 7145 4616716
Eczema 61.29 22.52 38 15093 5883 4617978
Respiratory tract congestion 61.24 22.52 32 15099 3579 4620282
Road traffic accident 60.46 22.52 43 15088 8366 4615495
Flushing 60.06 22.52 61 15070 19291 4604570
Dermatitis allergic 59.98 22.52 31 15100 3389 4620472
Lung disorder 59.87 22.52 50 15081 12321 4611540
Toxic epidermal necrolysis 59.73 22.52 38 15093 6154 4617707
C-reactive protein abnormal 59.30 22.52 22 15109 1078 4622783
Kounis syndrome 58.89 22.52 20 15111 755 4623106
Neoplasm malignant 58.49 22.52 47 15084 10974 4612887
Dermatitis bullous 58.36 22.52 29 15102 2918 4620943
Intervertebral disc degeneration 58.25 22.52 27 15104 2329 4621532
Hiatus hernia 57.42 22.52 30 15101 3354 4620507
Pulmonary oedema 57.35 22.52 53 15078 14933 4608928
Transposition of the great vessels 56.95 22.52 16 15115 316 4623545
Bunion operation 56.33 22.52 14 15117 168 4623693
Haemorrhage subcutaneous 56.27 22.52 22 15109 1245 4622616
Visual impairment 56.17 22.52 59 15072 19401 4604460
Glaucoma 56.11 22.52 30 15101 3514 4620347
White blood cell count abnormal 55.90 22.52 22 15109 1267 4622594
Dry mouth 55.37 22.52 49 15082 13052 4610809
Mouth ulceration 55.03 22.52 36 15095 6114 4617747
Generalised oedema 54.97 22.52 32 15099 4419 4619442
Red blood cell sedimentation rate abnormal 54.41 22.52 18 15113 626 4623235
Hypoacusis 54.19 22.52 36 15095 6273 4617588
Spinal stenosis 54.00 22.52 25 15106 2151 4621710
Rheumatoid nodule 53.85 22.52 19 15112 805 4623056
Hepatic cirrhosis 53.65 22.52 34 15097 5468 4618393
Bone swelling 53.50 22.52 15 15116 294 4623567
Blood pressure fluctuation 53.49 22.52 30 15101 3860 4620001
Joint stiffness 53.33 22.52 35 15096 5976 4617885
Purpura senile 53.30 22.52 10 15121 25 4623836
Inflammatory bowel disease 53.30 22.52 21 15110 1213 4622648
Duodenal ulcer perforation 53.29 22.52 18 15113 668 4623193
Peritonitis 52.86 22.52 34 15097 5611 4618250
Stomatitis 52.64 22.52 53 15078 16586 4607275
Embolism 52.63 22.52 28 15103 3247 4620614
Ependymoma 52.56 22.52 11 15120 56 4623805
Delirium 52.52 22.52 47 15084 12705 4611156
Speech disorder 52.40 22.52 45 15086 11517 4612344
Alopecia 52.35 22.52 68 15063 28012 4595849
Ulcer haemorrhage 52.05 22.52 20 15111 1080 4622781
Acute generalised exanthematous pustulosis 51.80 22.52 27 15104 3003 4620858
Impaired healing 51.14 22.52 39 15092 8440 4615421
Urine output decreased 50.92 22.52 27 15104 3110 4620751
Neuropathy peripheral 49.97 22.52 61 15070 23608 4600253
Candida infection 49.92 22.52 32 15099 5249 4618612
Dysstasia 49.90 22.52 31 15100 4816 4619045
Decreased appetite 49.83 22.52 97 15034 56300 4567561
Enthesopathy 49.67 22.52 14 15117 280 4623581
Malignant polyp 49.36 22.52 9 15122 18 4623843
Cystitis 49.09 22.52 36 15095 7344 4616517
Procedural haemorrhage 48.96 22.52 19 15112 1054 4622807
Liver function test abnormal 48.70 22.52 48 15083 14644 4609217
Small intestine ulcer 48.16 22.52 13 15118 220 4623641
Tubulointerstitial nephritis 47.98 22.52 33 15098 6086 4617775
Vision blurred 47.70 22.52 61 15070 24742 4599119
Gastrointestinal ulcer 47.65 22.52 17 15114 744 4623117
Hepatotoxicity 47.49 22.52 37 15094 8262 4615599
Leukopenia 47.49 22.52 57 15074 21679 4602182
Rash pruritic 47.47 22.52 44 15087 12439 4611422
Gallbladder disorder 47.08 22.52 28 15103 4022 4619839
Memory impairment 47.05 22.52 55 15076 20348 4603513
Treatment noncompliance 46.92 22.52 43 15088 11984 4611877
Heart rate irregular 46.74 22.52 29 15102 4495 4619366
Heart rate decreased 46.40 22.52 34 15097 6926 4616935
Heart rate increased 46.15 22.52 52 15079 18490 4605371
Discomfort 45.52 22.52 36 15095 8214 4615647
Respiratory failure 45.32 22.52 66 15065 30260 4593601
Post procedural complication 44.96 22.52 31 15100 5740 4618121
Bone marrow failure 44.81 22.52 43 15088 12695 4611166
Sudden death 44.65 22.52 30 15101 5325 4618536
Hepatitis 44.45 22.52 42 15089 12163 4611698
Spinal fracture 44.43 22.52 27 15104 4033 4619828
Limb injury 44.30 22.52 27 15104 4054 4619807
Scar 44.25 22.52 24 15107 2892 4620969
Dysarthria 44.08 22.52 42 15089 12290 4611571
Ventricular extrasystoles 44.03 22.52 27 15104 4099 4619762
Hepatitis cholestatic 43.65 22.52 23 15108 2615 4621246
Spinal osteoarthritis 43.59 22.52 23 15108 2623 4621238
Death 43.58 22.52 208 14923 197955 4425906
Lower respiratory tract infection 43.44 22.52 38 15093 9965 4613896
Nervousness 42.99 22.52 34 15097 7758 4616103
Tarsal tunnel syndrome 42.97 22.52 9 15122 46 4623815
Fluid retention 42.93 22.52 40 15091 11381 4612480
Metabolic surgery 42.71 22.52 12 15119 237 4623624
Hepatocellular injury 42.58 22.52 34 15097 7866 4615995
Cholestasis 42.50 22.52 34 15097 7886 4615975
Hip arthroplasty 42.48 22.52 23 15108 2762 4621099
Emphysema 42.46 22.52 22 15109 2417 4621444
Pulmonary congestion 42.44 22.52 26 15105 3940 4619921
Sinusitis 42.32 22.52 55 15076 22657 4601204
Throat tightness 41.87 22.52 31 15100 6415 4617446
Musculoskeletal discomfort 41.57 22.52 24 15107 3262 4620599
Groin pain 41.54 22.52 21 15110 2192 4621669
Back injury 41.30 22.52 19 15112 1611 4622250
Balance disorder 41.16 22.52 46 15085 16210 4607651
Scoliosis 41.14 22.52 18 15113 1356 4622505
Dermatitis exfoliative 40.70 22.52 23 15108 3003 4620858
Skin ulcer 40.67 22.52 32 15099 7246 4616615
Mitral valve incompetence 40.65 22.52 27 15104 4701 4619160
Hepatic steatosis 40.57 22.52 30 15101 6198 4617663
Tenderness 40.43 22.52 23 15108 3040 4620821
Disseminated intravascular coagulation 39.93 22.52 32 15099 7441 4616420
Gastrointestinal ulcer haemorrhage 39.59 22.52 12 15119 312 4623549
Platelet count decreased 39.55 22.52 67 15064 34935 4588926
Frequent bowel movements 39.28 22.52 24 15107 3619 4620242
Surgery 39.25 22.52 35 15096 9412 4614449
Joint injury 39.23 22.52 24 15107 3628 4620233
Nerve compression 39.17 22.52 18 15113 1522 4622339
Substance-induced psychotic disorder 39.00 22.52 14 15117 624 4623237
Carpal tunnel syndrome 38.86 22.52 22 15109 2882 4620979
Haematocrit decreased 38.76 22.52 34 15097 8948 4614913
Antinuclear antibody positive 38.56 22.52 18 15113 1578 4622283
Pancytopenia 38.46 22.52 55 15076 24798 4599063
Influenza like illness 38.24 22.52 48 15083 19105 4604756
Neutropenia 38.19 22.52 79 15052 47871 4575990
Blood pressure systolic increased 38.01 22.52 25 15106 4283 4619578
Iron deficiency anaemia 38.01 22.52 23 15108 3409 4620452
Large intestine polyp 37.98 22.52 20 15111 2271 4621590
Gastritis erosive 37.92 22.52 19 15112 1946 4621915
Agranulocytosis 37.65 22.52 31 15100 7486 4616375
Chronic kidney disease 37.56 22.52 36 15095 10609 4613252
Ischaemic stroke 37.52 22.52 31 15100 7523 4616338
Oliguria 37.13 22.52 21 15110 2746 4621115
Quality of life decreased 37.09 22.52 17 15114 1429 4622432
Peripheral vascular disorder 36.87 22.52 18 15113 1743 4622118
Seizure 36.81 22.52 80 15051 50157 4573704
Transaminases increased 36.80 22.52 34 15097 9572 4614289
Gastroenteritis 36.72 22.52 27 15104 5528 4618333
Wrist fracture 36.47 22.52 19 15112 2111 4621750
Benign abdominal neoplasm 36.43 22.52 6 15125 4 4623857
Cyanosis 36.16 22.52 28 15103 6194 4617667
Adverse drug reaction 36.11 22.52 41 15090 14698 4609163
Malignant neoplasm progression 36.06 22.52 58 15073 28978 4594883
Acute coronary syndrome 35.89 22.52 24 15107 4226 4619635
Facial paralysis 35.89 22.52 25 15106 4705 4619156
Chromaturia 35.85 22.52 27 15104 5734 4618127
Respiratory arrest 35.75 22.52 39 15092 13381 4610480
Epistaxis 35.71 22.52 47 15084 19596 4604265
No adverse event 35.70 22.52 50 15081 22113 4601748
Internal haemorrhage 35.64 22.52 16 15115 1281 4622580
Cholelithiasis 35.48 22.52 33 15098 9369 4614492
Cardio-respiratory arrest 35.38 22.52 47 15084 19775 4604086
Ankle fracture 35.37 22.52 21 15110 3006 4620855
Hernia 35.36 22.52 20 15111 2615 4621246
Cardiac murmur 35.19 22.52 21 15110 3034 4620827
Chills 34.98 22.52 57 15074 28782 4595079
Erosive oesophagitis 34.90 22.52 13 15118 644 4623217
Aphthous ulcer 34.89 22.52 19 15112 2308 4621553
Hand deformity 34.78 22.52 16 15115 1356 4622505
Bursitis 34.78 22.52 20 15111 2698 4621163
Metabolic acidosis 34.62 22.52 37 15094 12403 4611458
Sacroiliitis 34.62 22.52 12 15119 482 4623379
Chest expansion decreased 34.43 22.52 7 15124 30 4623831
Nephrotic syndrome 34.08 22.52 20 15111 2803 4621058
Large intestinal ulcer 34.03 22.52 14 15117 905 4622956
Disturbance in attention 34.01 22.52 34 15097 10547 4613314
Hyperlipidaemia 34.00 22.52 25 15106 5120 4618741
Pleural effusion 33.44 22.52 51 15080 24347 4599514
Type 2 diabetes mellitus 33.42 22.52 23 15108 4244 4619617
Lip swelling 33.38 22.52 30 15101 8149 4615712
Atrial flutter 33.33 22.52 21 15110 3342 4620519
Haemorrhagic stroke 33.21 22.52 19 15112 2538 4621323
Meniscus injury 32.93 22.52 16 15115 1533 4622328
Hepatic failure 32.93 22.52 37 15094 13112 4610749
Disorientation 32.82 22.52 36 15095 12423 4611438
Respiratory distress 32.60 22.52 34 15097 11082 4612779
Oral candidiasis 32.58 22.52 21 15110 3476 4620385
Loss of employment 32.29 22.52 10 15121 280 4623581
Limb discomfort 32.21 22.52 24 15107 5014 4618847
Rib fracture 32.13 22.52 23 15108 4519 4619342
Gastric perforation 32.04 22.52 13 15118 811 4623050
Blood urine present 31.87 22.52 22 15109 4079 4619782
Dysuria 31.64 22.52 29 15102 8081 4615780
Obesity 31.56 22.52 19 15112 2789 4621072
Angina unstable 31.54 22.52 21 15110 3671 4620190
Eyelid oedema 31.40 22.52 22 15109 4177 4619684
Hysterectomy 31.40 22.52 16 15115 1698 4622163
Vasculitis 30.97 22.52 22 15109 4269 4619592
Myocardial ischaemia 30.95 22.52 25 15106 5877 4617984
Joint destruction 30.93 22.52 11 15120 477 4623384
Colitis microscopic 30.91 22.52 15 15116 1433 4622428
Erythema nodosum 30.88 22.52 14 15117 1147 4622714
Oculomucocutaneous syndrome 30.66 22.52 9 15122 209 4623652
Depressed level of consciousness 30.28 22.52 38 15093 15116 4608745
Plantar fasciitis 30.23 22.52 12 15119 707 4623154
Sciatica 30.23 22.52 19 15112 3012 4620849
Liver injury 30.21 22.52 23 15108 4962 4618899
Spinal disorder 30.19 22.52 16 15115 1840 4622021
Economic problem 30.18 22.52 12 15119 710 4623151
Ventricular hypertrophy 30.14 22.52 15 15116 1514 4622347
Amnesia 30.06 22.52 35 15096 12886 4610975
Haematuria 29.95 22.52 35 15096 12935 4610926
Adrenal suppression 29.95 22.52 10 15121 358 4623503
Acute pulmonary oedema 29.85 22.52 18 15113 2651 4621210
Hypokalaemia 29.73 22.52 42 15089 18718 4605143
Tongue oedema 29.59 22.52 15 15116 1574 4622287
Failure to anastomose 29.51 22.52 7 15124 68 4623793
Arteriosclerosis coronary artery 29.48 22.52 19 15112 3145 4620716
Laryngeal oedema 29.17 22.52 17 15114 2351 4621510
Rhinitis 29.15 22.52 16 15115 1973 4621888
Ventricular septal defect 29.13 22.52 17 15114 2358 4621503
Diverticulum intestinal haemorrhagic 28.93 22.52 11 15120 577 4623284
Blood triglycerides increased 28.87 22.52 23 15108 5302 4618559
Ulcerative keratitis 28.80 22.52 13 15118 1054 4622807
Stab wound 28.55 22.52 7 15124 79 4623782
Haematoma 28.49 22.52 30 15101 9886 4613975
Throat irritation 28.46 22.52 26 15105 7212 4616649
Lymphopenia 28.41 22.52 23 15108 5424 4618437
Staphylococcal infection 28.36 22.52 31 15100 10657 4613204
Livedo reticularis 28.26 22.52 12 15119 840 4623021
Joint noise 28.23 22.52 12 15119 842 4623019
Vestibular disorder 28.06 22.52 10 15121 436 4623425
Subdural haematoma 27.87 22.52 24 15107 6162 4617699
Viral infection 27.84 22.52 27 15104 8071 4615790
Occult blood positive 27.82 22.52 13 15118 1142 4622719
Resorption bone increased 27.80 22.52 9 15122 292 4623569
Sleep apnoea syndrome 27.75 22.52 21 15110 4490 4619371
Thirst decreased 27.65 22.52 7 15124 91 4623770
Aphasia 27.56 22.52 28 15103 8852 4615009
Gastric ulcer perforation 27.53 22.52 10 15121 461 4623400
Therapeutic response unexpected 27.48 22.52 25 15106 6897 4616964
Rash papular 27.34 22.52 21 15110 4590 4619271
Hallucination 27.18 22.52 39 15092 17629 4606232
Post procedural infection 27.15 22.52 15 15116 1874 4621987
Extrasystoles 26.83 22.52 15 15116 1917 4621944
Intentional product use issue 26.83 22.52 25 15106 7110 4616751
Prescription drug used without a prescription 26.72 22.52 10 15121 502 4623359
Psoriatic arthropathy 26.66 22.52 24 15107 6534 4617327
Paraesthesia oral 26.56 22.52 18 15113 3240 4620621
Meniere's disease 26.49 22.52 9 15122 340 4623521
Altered state of consciousness 26.33 22.52 26 15105 7945 4615916
Skin exfoliation 26.18 22.52 30 15101 10857 4613004
Pain in jaw 26.13 22.52 27 15104 8705 4615156
Pruritus allergic 26.07 22.52 8 15123 217 4623644
Perforated ulcer 26.07 22.52 8 15123 217 4623644
Hypertensive crisis 25.93 22.52 20 15111 4399 4619462
Kidney infection 25.85 22.52 18 15113 3384 4620477
Forced expiratory volume decreased 25.84 22.52 12 15119 1039 4622822
Flatulence 25.80 22.52 26 15105 8138 4615723
Intermittent claudication 25.80 22.52 11 15120 778 4623083
Therapy non-responder 25.66 22.52 36 15095 15941 4607920
White blood cell count increased 25.42 22.52 35 15096 15232 4608629
Haemoptysis 25.41 22.52 27 15104 8987 4614874
Blood sodium decreased 25.37 22.52 22 15109 5700 4618161
Vascular purpura 25.34 22.52 10 15121 580 4623281
Rash macular 25.34 22.52 22 15109 5710 4618151
Soft tissue disorder 25.33 22.52 9 15122 389 4623472
Cardiac valve disease 25.23 22.52 13 15118 1411 4622450
Essential hypertension 25.20 22.52 11 15120 824 4623037
Dementia 25.15 22.52 21 15110 5171 4618690
Large intestinal haemorrhage 25.14 22.52 10 15121 592 4623269
Diplopia 25.03 22.52 23 15108 6428 4617433
Circulatory collapse 24.99 22.52 25 15106 7760 4616101
Ascites 24.97 22.52 31 15100 12194 4611667
Hemiparesis 24.93 22.52 23 15108 6461 4617400
Irritable bowel syndrome 24.87 22.52 16 15115 2640 4621221
Oesophageal ulcer 24.71 22.52 13 15118 1473 4622388
Dysgeusia 24.71 22.52 34 15097 14785 4609076
Vitreous detachment 24.54 22.52 10 15121 631 4623230
Helicobacter test positive 24.49 22.52 8 15123 267 4623594
Systemic lupus erythematosus 24.44 22.52 21 15110 5375 4618486
Sensitivity to weather change 24.36 22.52 10 15121 643 4623218
Product dispensing error 24.35 22.52 22 15109 6015 4617846
Blood creatine phosphokinase increased 24.22 22.52 34 15097 15065 4608796
Small intestinal obstruction 24.20 22.52 19 15112 4289 4619572
Dialysis 24.11 22.52 20 15111 4879 4618982
Lower gastrointestinal haemorrhage 24.10 22.52 15 15116 2336 4621525
Medication error 23.92 22.52 33 15098 14383 4609478
Cardiomegaly 23.83 22.52 20 15111 4957 4618904
Poor quality sleep 23.75 22.52 17 15114 3338 4620523
Dysphonia 23.75 22.52 28 15103 10446 4613415
Bronchospasm 23.74 22.52 21 15110 5585 4618276
Shock haemorrhagic 23.73 22.52 16 15115 2856 4621005
Lung neoplasm malignant 23.69 22.52 23 15108 6883 4616978
Amaurosis fugax 23.68 22.52 8 15123 297 4623564
Decreased activity 23.61 22.52 13 15118 1613 4622248
Carotid artery disease 23.58 22.52 9 15122 477 4623384
Hemiplegia 23.57 22.52 16 15115 2887 4620974
Axial spondyloarthritis 23.49 22.52 5 15126 28 4623833
Bronchitis 23.48 22.52 39 15092 20001 4603860
Coronary artery thrombosis 23.47 22.52 11 15120 973 4622888
Rash pustular 23.34 22.52 16 15115 2933 4620928
Coronary artery surgery 23.29 22.52 6 15125 84 4623777
Iron deficiency 23.23 22.52 11 15120 995 4622866
Arteriosclerosis 23.22 22.52 17 15114 3457 4620404
Miliaria 23.21 22.52 8 15123 316 4623545
Prothrombin time prolonged 23.19 22.52 17 15114 3464 4620397
Infusion related reaction 23.17 22.52 37 15094 18365 4605496
Visual acuity reduced 23.05 22.52 27 15104 10003 4613858
Deafness 23.01 22.52 20 15111 5199 4618662
Blood loss anaemia 22.71 22.52 14 15117 2144 4621717
Cardiac flutter 22.65 22.52 11 15120 1053 4622808
Vertigo positional 22.58 22.52 9 15122 536 4623325
Compression fracture 22.57 22.52 12 15119 1389 4622472
Dyspnoea exertional 22.53 22.52 27 15104 10245 4613616

Pharmacologic Action:

SourceCodeDescription
ATC C08CA51 CARDIOVASCULAR SYSTEM
CALCIUM CHANNEL BLOCKERS
SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Dihydropyridine derivatives
ATC L01XX33 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
OTHER ANTINEOPLASTIC AGENTS
Other antineoplastic agents
ATC M01AH01 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Coxibs
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D052246 Cyclooxygenase 2 Inhibitors
MeSH PA D016861 Cyclooxygenase Inhibitors
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents
CHEBI has role CHEBI:35481 non-narcotic analgesic
FDA EPC N0000175722 Nonsteroidal Anti-inflammatory Drug
FDA Chemical/Ingredient N0000175721 Nonsteroidal Anti-inflammatory Compounds

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Ankylosing spondylitis indication 9631008 DOID:7147
Rheumatoid arthritis indication 69896004 DOID:7148
Dysmenorrhea indication 266599000
Osteoarthritis indication 396275006
Juvenile rheumatoid arthritis indication 410795001
Acute postoperative pain indication 107401000119105
Alcoholism contraindication 7200002
Peptic ulcer contraindication 13200003 DOID:750
Myocardial infarction contraindication 22298006 DOID:5844
Dehydration contraindication 34095006
Hypertensive disorder contraindication 38341003 DOID:10763
Gastrointestinal ulcer contraindication 40845000
Body fluid retention contraindication 43498006
Chronic heart failure contraindication 48447003
Disorder of cardiovascular system contraindication 49601007 DOID:1287
Gastrointestinal perforation contraindication 51875005
Acute nephropathy contraindication 58574008
Gastrointestinal hemorrhage contraindication 74474003
Kidney disease contraindication 90708001 DOID:557
Liver function tests abnormal contraindication 166603001
Asthma contraindication 195967001 DOID:2841
Cerebrovascular accident contraindication 230690007
Coronary artery bypass graft contraindication 232717009
Disease of liver contraindication 235856003 DOID:409
Edema contraindication 267038008
Anemia contraindication 271737000 DOID:2355
Pregnancy, function contraindication 289908002
Thromboembolic disorder contraindication 371039008
Cardiovascular event risk contraindication 395112001
Smokes tobacco daily contraindication 449868002

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.79 acidic

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
200MG CONSENSI COEPTIS N210045 May 31, 2018 RX TABLET ORAL 9662315 May 22, 2029 TREATMENT OF ADULT PATIENTS FOR WHOM TREATMENT WITH BOTH AMLODIPINE FOR HYPERTENSION AND CELECOXIB FOR OSTEOARTHRITIS ARE APPROPRIATE

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
200MG CONSENSI COEPTIS N210045 May 31, 2018 RX TABLET ORAL May 31, 2021 NEW COMBINATION

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Prostaglandin G/H synthase 2 Enzyme INHIBITOR IC50 7.24 WOMBAT-PK CHEMBL
Sodium-dependent serotonin transporter Transporter Ki 5.48 DRUG MATRIX
Sodium-dependent noradrenaline transporter Transporter Ki 5.14 DRUG MATRIX
Alpha-2B adrenergic receptor GPCR Ki 6.16 DRUG MATRIX
Beta-3 adrenergic receptor GPCR Ki 4.92 DRUG MATRIX
Cytochrome P450 2D6 Enzyme IC50 6 DRUG MATRIX
Adenosine receptor A3 GPCR Ki 4.86 DRUG MATRIX
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Enzyme IC50 5.03 DRUG MATRIX
Carbonic anhydrase 2 Enzyme IC50 7.68 WOMBAT-PK
Sodium-dependent dopamine transporter Transporter Ki 6.18 WOMBAT-PK
Carbonic anhydrase 12 Enzyme Ki 7.74 CHEMBL
Carbonic anhydrase 4 Enzyme Ki 6.06 CHEMBL
Carbonic anhydrase 13 Enzyme Ki 7.01 CHEMBL
Prostaglandin G/H synthase 1 Enzyme IC50 7.30 CHEMBL
Carbonic anhydrase 3 Enzyme Ki 5.13 CHEMBL
3-phosphoinositide-dependent protein kinase 1 Kinase IC50 4.32 CHEMBL
Carbonic anhydrase 5A, mitochondrial Enzyme Ki 6.10 CHEMBL
Carbonic anhydrase 14 Enzyme Ki 6.16 CHEMBL
Carbonic anhydrase 7 Enzyme Ki 5.66 CHEMBL
Carbonic anhydrase 9 Enzyme Ki 4.80 CHEMBL
Carbonic anhydrase 1 Enzyme Ki 4.30 CHEMBL
Carbonic anhydrase 5B, mitochondrial Enzyme Ki 7.03 CHEMBL
Carbonic anhydrase 6 Enzyme Ki 7.03 CHEMBL
Mitogen-activated protein kinase 14 Kinase IC50 6.09 CHEMBL
D(1A) dopamine receptor GPCR Ki 4.85 DRUG MATRIX
Progesterone receptor Transcription factor Ki 5.63 DRUG MATRIX
Cytochrome c oxidase subunit 2 Enzyme IC50 7.22 CHEMBL
Prostaglandin G/H synthase 1 Enzyme IC50 8.43 CHEMBL
Carbonic anhydrase Enzyme Ki 4.41 CHEMBL
Alpha carbonic anhydrase Unclassified Ki 7.47 CHEMBL
Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase Enzyme Ki 5.11 CHEMBL
Prostaglandin G/H synthase 2 Enzyme IC50 7.40 CHEMBL
Prostaglandin G/H synthase 2 Enzyme IC50 7.24 CHEMBL
Prostaglandin G/H synthase 2 Enzyme IC50 9.29 CHEMBL
Prostaglandin G/H synthase 1 Enzyme IC50 9.15 CHEMBL
Astrosclerin-3 Unclassified Ki 6.14 CHEMBL
Prostaglandin G/H synthase 2 Enzyme IC50 5.96 CHEMBL
Beta-carbonic anhydrase 1 Enzyme Ki 4.99 CHEMBL
Carbonic anhydrase Unclassified Ki 6.16 CHEMBL
Delta carbonic anhydrase Unclassified Ki 6.58 CHEMBL
Carbonic anhydrase Enzyme Ki 6.97 CHEMBL
Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein Enzyme IC50 6.05 CHEMBL
Prostaglandin G/H synthase 1 Enzyme IC50 5.25 CHEMBL
Prostaglandin G/H synthase 1 Enzyme IC50 4.85 CHEMBL
Carbonic anhydrase 15 Enzyme Ki 7.35 CHEMBL
Prostaglandin G/H synthase 1 Enzyme IC50 5.11 CHEMBL
Cytochrome c oxidase subunit 1 Unclassified IC50 4.61 CHEMBL
Carbonic anhydrase Enzyme Ki 7.68 CHEMBL
Carbonic anhydrase Enzyme Ki 6.85 CHEMBL
Carbonic anhydrase 2 Enzyme Ki 6.15 CHEMBL
Carbonic anhydrase 4 Enzyme Ki 6.54 CHEMBL
Carbonic anhydrase Unclassified Ki 6.76 CHEMBL
Carbonic anhydrase Enzyme Ki 6.94 CHEMBL

External reference:

IDSource
D000068579 MESH_DESCRIPTOR_UI
4021143 VUID
N0000148596 NUI
C0538927 UMLSCUI
D00567 KEGG_DRUG
370187009 SNOMEDCT_US
4021143 VANDF
007731 NDDF
174627 MMSL
d04380 MMSL
7872 MMSL
140587 RXNORM
116081000 SNOMEDCT_US
CHEMBL118 ChEMBL_ID
DB00482 DRUGBANK_ID
JCX84Q7J1L UNII
7767 INN_ID
CEL PDB_CHEM_ID
CHEBI:41423 CHEBI
2892 IUPHAR_LIGAND_ID
2662 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CELEBREX HUMAN PRESCRIPTION DRUG LABEL 1 0025-1515 CAPSULE 50 mg ORAL NDA 20 sections
CELEBREX HUMAN PRESCRIPTION DRUG LABEL 1 0025-1520 CAPSULE 100 mg ORAL NDA 20 sections
CELEBREX HUMAN PRESCRIPTION DRUG LABEL 1 0025-1525 CAPSULE 200 mg ORAL NDA 20 sections
CELEBREX HUMAN PRESCRIPTION DRUG LABEL 1 0025-1530 CAPSULE 400 mg ORAL NDA 20 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0093-7165 CAPSULE 100 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0093-7166 CAPSULE 200 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0093-7170 CAPSULE 400 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0093-7306 CAPSULE 50 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0378-7150 CAPSULE 200 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0378-7160 CAPSULE 100 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0378-7165 CAPSULE 50 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0378-7170 CAPSULE 400 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0591-3982 CAPSULE 50 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0591-3983 CAPSULE 100 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0591-3984 CAPSULE 200 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0591-3985 CAPSULE 400 mg ORAL ANDA 19 sections
celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0615-8297 CAPSULE 200 mg ORAL ANDA 19 sections
celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0615-8338 CAPSULE 200 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0904-6502 CAPSULE 100 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 0904-6503 CAPSULE 200 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 10544-917 CAPSULE 200 mg ORAL NDA authorized generic 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 10544-918 CAPSULE 200 mg ORAL NDA authorized generic 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 10544-929 CAPSULE 200 mg ORAL NDA authorized generic 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 10544-953 CAPSULE 200 mg ORAL ANDA 19 sections
Celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 10544-967 CAPSULE 200 mg ORAL NDA authorized generic 19 sections
celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 13668-307 CAPSULE 50 mg ORAL ANDA 19 sections
celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 13668-310 CAPSULE 400 mg ORAL ANDA 19 sections
celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 13668-441 CAPSULE 100 mg ORAL ANDA 19 sections
celecoxib HUMAN PRESCRIPTION DRUG LABEL 1 13668-442 CAPSULE 200 mg ORAL ANDA 19 sections
CELEBREX HUMAN PRESCRIPTION DRUG LABEL 1 16590-045 CAPSULE 100 mg ORAL NDA 19 sections