All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

cefcapene pivoxil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
antibiotics, cefalosporanic acid derivatives	532	105889-45-0

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: cefcapene pivoxil cefcamate pivoxil cefcapene pivoxil hydrochloride cefcapene pivoxil HCl	Molecular weight: 567.63 Formula: C23H29N5O8S2 CLOGP: 1.01 LIPINSKI: 2 HAC: 13 HDO: 3 TPSA: 193.24 ALOGS: -4.79 ROTB: 13

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

Property	Description	Value	Unit	Confidence	Similarity
kinase-safety-class	ACVR2A,ACVR2B,AKT2,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK2,MAP3K1,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MARK4,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIM2,PLK1,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1	49
kinase-selectivity-class	AXL,BRAF,CDK9,DDR1,EPHB4,GRK2,MAPK7,STK33,TEK	9
pfas-class	PFAS structural alert (1 = True, 0 = False)	0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Nerve degeneration	74.98	43.60	11	917	194	42620213
Renal neoplasm	53.30	43.60	11	917	1464	42618943
Abdominal rigidity	52.65	43.60	11	917	1554	42618853
Renal mass	49.95	43.60	11	917	1991	42618416
Bone density decreased	48.89	43.60	11	917	2195	42618212

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Nerve degeneration	77.81	36.62	11	1321	275	110587692
Renal neoplasm	54.40	36.62	11	1321	2395	110585572
Renal mass	49.88	36.62	11	1321	3624	110584343
Abdominal rigidity	49.75	36.62	11	1321	3669	110584298
Metastasis	40.90	36.62	11	1321	8256	110579711

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
CHEBI has role	CHEBI:36047	antibacterial drug

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	3.58	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
C3273882	UMLSCUI
147816-23-7	SECONDARY_CAS_RN
8I8MJ56XFQ	UNII
5282438	PUBCHEM_CID
C2699134	UMLSCUI
CHEBI:42709	CHEBI
DB13461	DRUGBANK_ID
6436055	PUBCHEM_CID
7006	INN_ID
C425944	MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:131729	CHEBI
8I8MJ56XFQ	INXIGHT DRUGS

Pharmaceutical products:

None