rubidium Rb-82 chloride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5184 132486-03-4

Description:

MoleculeDescription

Synonyms:

  • rubidium chloride Rb-82
  • rubidium Rb-82 chloride
  • RUBY-FILL
  • Rubidium Chloride Rb 82
  • rubidium (82Rb) chloride
  • CARDIOGEN-82
Rb-82 is analogous to potassium ion (K+) in its biochemical behavior and is rapidly extracted by the myocardium proportional to the blood flow. Rb+ participates in the sodium-potassium (Na+/K+) ion exchange pumps that are present in cell membranes. The intracellular uptake of Rb-82 requires maintenance of ionic gradient across cell membranes. Rb-82 radioactivity is increased in viable myocardium reflecting intracellular retention, while the tracer is cleared rapidly from necrotic or infarcted tissue.
  • Molecular weight: 117.37
  • Formula: ClRb
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 29, 1989 FDA BRACCO

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Product preparation error 199.76 184.02 25 31 5768 79738564

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V09GX04 VARIOUS
DIAGNOSTIC RADIOPHARMACEUTICALS
CARDIOVASCULAR SYSTEM
Other cardiovascular system diagnostic radiopharmaceuticals

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Positron emission tomography indication 82918005




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEMBL1200727 ChEMBL_ID
D05773 KEGG_DRUG
71357 PUBCHEM_CID
1367086 RXNORM
213493 MMSL
30242 MMSL
d08248 MMSL
C1268555 UMLSCUI
F0Z746KRKQ UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CardioGen-82 HUMAN PRESCRIPTION DRUG LABEL 1 0270-0091 INJECTION, SOLUTION 150 mCi INTRAVENOUS NDA 25 sections
CardioGen-82 HUMAN PRESCRIPTION DRUG LABEL 1 0270-0091 INJECTION, SOLUTION 150 mCi INTRAVENOUS NDA 25 sections
RUBY-FILL Human Prescription Drug Label 1 65174-021 INJECTION, SOLUTION 100 mCi INTRAVENOUS NDA 24 sections