carpipramine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
substances of the imipramine group	517	5942-95-0

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

carpipramine maleate
carpipramine hydrochloride
defekton
carpipramine dihydrochloride
carpipramine
carbadipimidine
prazinil
carpipramine HCl

Molecular weight: 446.64
Formula: C28H38N4O
CLOGP: 4.96
LIPINSKI: 0
HAC: 5
HDO: 1
TPSA: 52.81
ALOGS: -4.60
ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D014151	Anti-Anxiety Agents
MeSH PA	D002491	Central Nervous System Agents
MeSH PA	D002492	Central Nervous System Depressants
MeSH PA	D011619	Psychotropic Drugs
MeSH PA	D014149	Tranquilizing Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	8.96	Basic
pKa2	6.19	Basic
pKa3	5.01	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
D(2) dopamine receptor	GPCR	P14416	DRD2_HUMAN		Ki	8.06		PDSP
D(3) dopamine receptor	GPCR	P35462	DRD3_HUMAN		Ki	7.82		PDSP

External reference:

ID	Source
D01449	KEGG_DRUG
100482-23-3	SECONDARY_CAS_RN
60452-13-3	SECONDARY_CAS_RN
20342	RXNORM
C0054826	UMLSCUI
CHEBI:31361	CHEBI
CHEMBL2110775	ChEMBL_ID
CHEMBL3989549	ChEMBL_ID
C006922	MESH_SUPPLEMENTAL_RECORD_UI
1989	INN_ID
8AFK6F91EQ	UNII
2580	PUBCHEM_CID
005388	NDDF
005389	NDDF

Pharmaceutical products:

None