moroctocog alfa 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
blood factor VIII 5166 284036-24-4

Description:

MoleculeDescription

Synonyms:

  • moroctocog alfa
  • ReFacto AF
Human coagulation factor VIII produced by recombinant DNA technology in Chinese hamster ovary (CHO) cells. Moroctocog alfa is a glycoprotein with 1438 amino acids with a sequence that is comparable to the 90 + 80 kDa form of factor VIII (i.e. B-domain deleted) and similar post-translational modifications to those of the plasma-derived molecule
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
April 13, 1999 EMA Pfizer Ltd

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hereditary factor VIII deficiency disease indication 28293008 DOID:12134




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
113E3Z3CJJ UNII
4019616 VANDF
4029702 VANDF
C0966500 UMLSCUI
CHEMBL2109137 ChEMBL_ID
DB13999 DRUGBANK_ID
7044 INN_ID
1300485 RXNORM
d00525 MMSL
d05974 MMSL
002035 NDDF
003830 NDDF
278910002 SNOMEDCT_US
416523005 SNOMEDCT_US
441764007 SNOMEDCT_US
441943001 SNOMEDCT_US
C0015506 UMLSCUI

Pharmaceutical products:

None