gluconolactone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5144 | 90-80-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Oct. 2, 1990 | FDA | UNITED GUARDIAN |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| FDA MoA | N0000175534 | Irrigation |
| FDA EPC | N0000175835 | Calculi Dissolution Agent |
| CHEBI has role | CHEBI:75767 | animal metabolites |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Urinary bladder stone | indication | 70650003 | DOID:11355 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.96 | acidic |
| pKa2 | 12.58 | acidic |
| pKa3 | 13.31 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Glucosylceramidase | Enzyme | Ki | 4.52 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| WQ29KQ9POT | UNII |
| 4019568 | VANDF |
| C0061387 | UMLSCUI |
| CHEBI:16217 | CHEBI |
| LGC | PDB_CHEM_ID |
| CHEMBL1200829 | ChEMBL_ID |
| D04332 | KEGG_DRUG |
| 7027 | PUBCHEM_CID |
| DB04564 | DRUGBANK_ID |
| 25842 | RXNORM |
| NOCODE | MMSL |
| d03715 | MMSL |
| 005159 | NDDF |
| 427638006 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Renacidin | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0327-0012 | SOLUTION | 0.20 g | IRRIGATION | NDA | 14 sections |
| DR.PLINUS ZERO TROUBLE | HUMAN OTC DRUG LABEL | 3 | 72630-030 | PATCH | 0.03 mg | TOPICAL | unapproved drug other | 10 sections |
| DR.PLINUS ZERO TROUBLE | HUMAN OTC DRUG LABEL | 3 | 72630-030 | PATCH | 0.03 mg | TOPICAL | unapproved drug other | 10 sections |