oxiglutatione 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5130 | 27025-41-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:76971 | Escherichia coli metabolites |
| CHEBI has role | CHEBI:75772 | S. cerevisiae metabolites |
| CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 1.67 | acidic |
| pKa2 | 2.27 | acidic |
| pKa3 | 3.26 | acidic |
| pKa4 | 3.86 | acidic |
| pKa5 | 11.86 | acidic |
| pKa6 | 12.46 | acidic |
| pKa7 | 13.72 | acidic |
| pKa8 | 9.96 | Basic |
| pKa9 | 9.36 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEBI:17858 | CHEBI |
| D00031 | KEGG_DRUG |
| CHEMBL1372 | ChEMBL_ID |
| 6835 | IUPHAR_LIGAND_ID |
| DB03310 | DRUGBANK_ID |
| 25953 | RXNORM |
| 4789 | MMSL |
| 005967 | NDDF |
| C0061516 | UMLSCUI |
| GDS | PDB_CHEM_ID |
| 6698 | INN_ID |
| 65359 | PUBCHEM_CID |
| D019803 | MESH_DESCRIPTOR_UI |
| ULW86O013H | UNII |
Pharmaceutical products:
None